The Edpm5 locus prevents the 'angiogenic switch' in an estrogen-induced rat putuitary tumor

Carcinogenesis

Volumn 25, Issue 10, 2004, Pages 1829-1838

  Pandey, Jyotsna ^a   Bannout, Anas ^a   Wendell, Douglas L ^a  

^a OAKLAND UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; PROLACTIN; RETICULIN; VASCULOTROPIN;

ALLELE; ANGIOGENESIS; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE LOCUS; HISTOPATHOLOGY; HOMOZYGOSITY; HYPOPHYSIS TUMOR; IMMUNOHISTOCHEMISTRY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RAT; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TUMOR GROWTH; TUMOR VASCULARIZATION; WESTERN BLOTTING;

ADENOMA; ANIMALS; ANIMALS, CONGENIC; ESTROGENS; FEMALE; NEOPLASMS, HORMONE-DEPENDENT; NEOVASCULARIZATION, PATHOLOGIC; PITUITARY NEOPLASMS; QUANTITATIVE TRAIT LOCI; RATS; RATS, INBRED BN; RATS, INBRED F344; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 6444234767     PISSN: 01433334     EISSN: None     Source Type: Journal    
DOI: 10.1093/carcin/bgh192     Document Type: Article

References (65)

1. Wiklund,J., Rutledge,J. and Gorski,J. (1981) A genetic model for the inheritance of pituitary tumor susceptibility in F344 rats. Endocrinology, 109, 1708-1714.
2. Schechter,J., Ahmad,N., Elias,K.A. and Weiner,R. (1987) Estrogen-induced tumors: changes in the vasculature in two strains of rat. Am. J. Anat., 179, 315-323.
3. De Nicola,A.F., van Lawzewitsch,I., Kaplan,S.E. and Libertun,C. (1978) Biochemical and ultrastructural studies on estrogen-induced pituitary tumors in F344 rats. J. Natl Cancer Inst. 61, 753-763.
4. Wiklund,J. and Gorski,J. (1982) Genetic differences in estrogen-induced deoxyribonucleic acid synthesis in the rat pituitary: correlations with pituitary tumor susceptability. Endocrinology, 111, 1140-1149.
5. Wendell,D.L,, Herman,A. and Gorski,J. (1996) Genetic separation of tumor growth and hemorrhagic phenotypes in an estrogen-induced tumor. Proc. Natl Acad. Sci. USA, 93, 8112-8116.
6. Holtzman,S., Stone,J.P. and Shellabarger,C.J. (1979) Influence of diethylstilbestrol treatment on prolactin cells in female ACI and Sprague-Dawley rats. Cancer Res., 39, 779-784.
7. Phelps,C. and Hymer,W.C. (1983) Characterization of estrogen-induced adenohypophyseal tumors in the Fischer 344 rat. Neuroendocrinology, 37, 23-31.
8. Lloyd,R.V. (1983) Estrogen-induced hyperplasia and neoplasia in the rat anterior pituitary gland: an immunohistochemical study. Am. J. Pathol., 113, 198-206.
9. Elias,K.A. and Weiner,R.I. (1984) Direct arterial vascularization of estrogen-induced prolactin-secreting anterior pituitary tumors. Proc. Natl Acad. Sci. USA, 81, 4549-4553.
10. Banerjee,S.K., Sarkar,D.K., Weston,A.P., De,A. and Campbell,D.R. (1997) Over expression of vascular endothelial growth factor and its receptor during the development of estrogen-induced rat pituitary tumors may mediate estrogen-initiated tumor angiogenesis. Carcinogenesis, 18, 1155-1161.
11. Pandey,J., Cracchiolo,D., Hansen,F.M. and Wendell,D.L. (2002) Strain differences and inheritance of angiogenic versus angiostatic activity in oestrogen-induced rat pituitary tumours. Angiogenesis, 5, 53-66.
12. Satoh,H., Kajimura,T., Chen,C.-D., Yamada,K., Furuhama,K. and Nomura,M. (1997) Invasive pituitary tumors in female F344 rats induced by estradiol dipropionate. Toxicologic. Pathol., 25, 462-469.
13. Carmeliet,P. and Jain,R. (2000) Angiogenesis in cancer and other diseases. Nature, 407, 249-257.
14. Takechi,A., Uozumi,T., Kawamoto,K., Ito,A., Kurisu,K. and Sudo,K. (1994) Inhibitory effect of TNP-470, a new anti-angiogenic agent, on the estrogen induced rat pituitary tumors. Anticancer Res., 14, 157-162.
15. Itoh,J., Kawai,K., Serizawa,A., Yamamoto,Y., Ogawa,K., Matsuno,A., Watanabe,K. and Osamura,Y. (2001) Three-dimensional imaging of hormone-secreting cells and their microvessel environment in estrogen-induced prolactinoma of the rat pituitary gland by confocal laser scanning microscopy. Appl. Immunohistochem. Mol. Morphol., 9, 364-370.
16. van Nesselrooij,J.H.J., Hendriksen,F.G.J., Feron,V.J. and Bosland,M.C. (1992) Pathogenesis of blood-filled cavities in estrogen-induced anterior pituitary tumors in male Sprague-Dawley rats. Toxicol. Pathol., 20, 71-80.
17. Tiboldi,T., Nemessanyi,Z., Csernay,I. and Kovacs,K. (1967) Effect of estrogen on pituitary blood flow in rats. Endocrinol. Exp. 2, 73-77.
18. Liotta,L.A., Steeg,P.S. and Stetler-Stevenson,W.G. (1991) Cancer metastasis and angiogenesis: an imbalance of postive and negative regulation. Cell, 64, 327-336.
19. Folkman,J. (1985) Tumor angiogenesis. Adv. Cancer Res., 43, 175-203.
20. Hanahan,D. and Folkman,J. (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell, 86, 353-364.
21. Folkman,J., Watson,K., Ingber,D. and Hanahan,D. (1989) Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature, 339, 58-61.
22. Chodak,G., Haudenschild,C., Gittes,R. and Folkman,J. (1980) Angiogenic activity as a marker of neoplastic and preneoplastic lesions of the human bladder. Ann. Surg., 192, 762-71.
23. Jensen,H., Chen,I., DeVault,M. and Lewis,A. (1982) Angiogenesis induced by 'normal' human breast tissue: a probable marker for precancer. Science, 218, 293-295.
24. Vermeulen,P.B., Gasparini,G., Fox,S.B. et al. (2002) Second international consensus on the methodology and criteria of evaluation of angiogenesis quantification in solid human tumours. Eur. J. Cancer, 38, 1564-1579.
25. Weidner,N. (2000) Angiogenesis as a predictor of clinical outcome in cancer patients. Hum. Pathol., 31, 403-405.
26. Turner,H.E., Nagy,Z., Gatter,K.C., Esiri,M.M., Harris,A.L. and Wass,J.A. (2000) Angiogenesis in pituitary adenomas and the normal pituitary gland. J. Clin. Endocrinol. Metabol., 85, 1159-1162.
27. Folkman,J. (1994) Angiogenesis and breast cancer. J. Clin. Oncol., 12, 441-443.
28. Wendell,D.L. and Gorski,J. (1997) Quantitative trait loci for estrogen-dependent pituitary tumor growth in the rat. Mamm. Genome, 8, 823-829.
29. Wendell,D.L., Daun,S.B., Stratton,M.B. and Gorski,J. (2000) Different functions of QTL for estrogen-dependent tumor growth of the rat pituitary. Mamm. Genome, 11, 855-861.
30. Sclafani,R.V. and Wendell,D.L. (2001) Suppression of estrogen-dependent MMP-9 expression by Edpm5, a genetic locus for pituitary tumor growth in rat. Mol. Cell. Endocrinol., 176, 145-153.
31. Cracchiolo,D., Swick,J.W., McKiernan,L., Sloan,E., Raina,S., Sloan,C. and Wendell,D.L. (2002) Estrogen-dependent growth of a rat pituitary tumor involves, but does not require, a high level of vascular endothelial growth factor. Exp. Biol. Med., 227, 492-499.
32. Ferrara,N. and Davis-Smyth,T. (1997) The biology of vascular endothelial growth factor. Endocrine Rev., 18, 4-25.
33. Pluda,J.M. (1997) Tumor associated angiogenesis: mechanisms, clinical implications and therapeutic strategies. Semin. Oncol., 24, 203-218.
34. Kohn,E.C. and Liotta,L.A. (1995) Molecular insights into cancer invasion: strategies for prevention and intervention. Cancer Res., 55, 1856-1862.
35. Bergers,G., Brekken,R., McMahon,G. et al. (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nature Cell Biol., 2, 737-744.
36. Tanksley,S.D. (1993) Mapping polygenes. Annu. Rev. Genet. 27, 205-233.
37. Markel,P., Shu,P., Ebeling,C., Carlson,G.A., Nagle,D.L., Smutko,J.S. and Moore,K.J. (1997) Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains. Nature Genet., 17, 280-284.
38. Wiklund,J., Wertz,N. and Gorski,J. (1981) A comparison of estrogen effects on uterine and pituitary growth and prolactin synthesis in F344 and Holtzman rats. Endocrinology, 109, 1700-1707.
39. Suhardja,A., Kovacs,K. and Rutka,J. (1999) Molecular pathogenesis of pituitary adenoma: a review. Acta Neurochir. (Wein 141, 729-736.
40. Culling,C., Allison,R. and Barr,W. (1985) Connective tissue. In Culling,C., Allison,R. and Barr,W. (eds) Cellular Pathology Techniques. Butterworth and Co. Ltd, London, pp. 173-174.
41. Shull,J.D., Birt,D.F., McComb,R.D., Spady,T.J., Pennington,K.L. and Shaw-Bruha,C.M. (1998) Estrogen induction of prolactin-producing pituitary tumors in the Fischer 344 rat: modulation by dietary-energy but not protein consumption. Mol. Carcinogen., 23, 96-105.
42. Weidner,N., Folkman,J. and Pozza,F. (1992) Tumor angiogenesis: a new significant and independent prognostic indicator in early stage breast carcinoma. J. Natl Cancer Inst., 84, 1875-1887.
43. Vermeulen,P.B., Gasparini,G., Fox,S.B. et al. (1996) Quantification of angiogenesis in solid human tumors: an international consensus on the methodology and criteria of evaluation. Eur. J. Cancer, 32A, 2474-2484.
44. Spady,T.J., Lemus-Wilson,A.M., Pennington,K.L., Blackwood,D.J., Paschall,T.M., Birt,D.F., McComb,R.D. and Shull,J.D. (1998) Dietary energy restriction abolishes development of prolactin-producing pituitary tumors in Fischer 344 rats treated with 17β-estradiol. Mol. Carcinogen., 23, 86-95.
45. Lloyd,R.V. and Mailloux,J. (1987) Effects of diethylstilbestrol and propylthiouracil on the rat pituitary. An immunohistochemical and ultrastructural study. J. Natl Cancer Inst. 79, 865-873.
46. Azad,N., Nayyar,R., Tentler,J., Cernius,M., Emanuele,N.V., Kirsteins,L. and Lawrence,A.M. (1989) Anatomical and functional effects of estrogen-induced prolactinomas on the rat hypothalamus. J. Exp. Pathol., 4, 237-249.
47. Schechter,J. (1972) Ultrastructural changes in the capillary bed of human pituitary tumors. Am. J. Pathol., 67, 109-126.
48. Kovacs,E. and Horvath,E. (1973) Vascular alterations in adenomas of human pituitary glands. Angiologica, 10, 299-309.
49. Sillman,F., Boyce,J. and Fruchter,R. (1981) The significance of atypical vessels and neovascularisation in cervical neoplasia. Am. J. Obstet. Gynecol., 139, 154-159.
50. Skinner,S.A., Frydman,G.M. and O'Brien,P.E. (1995) Microvascular structure of benign and malignant tumors of the colon in humans. Dig. Dis. Sci., 40, 373-384.
51. Huss,W., Hanrahan,C., Barrios,R., Simons,J. and Greenberg,N. (2001) Angiogenesis and prostate cancer: identification of a molecular progression switch. Cancer Res., 61, 2736-2743.
52. Daniel,P. and Prichard,M. (1975) Anatomy of the pituitary gland. Acta Endocrinol. (Copenhagen), 80 (suppl. 201), 27-65.
53. Hansen-Smith,F.M., Hudlicka,O. and Egginton,S. (1996) In vivo angiogenesis in adult rat skeletal muscle: early changes in capillary network architecture and ultrastructure. Cell. Tissue Res. 286, 123-136.
54. Zhou,A.L., Egginton,S., Brown,M.D. and Hudlicka,O. (1998) Capillary growth in overloaded, hypertrophic adult rat skeletal muscle: an ultrastructural study. Anatomic. Record., 252, 49-63.
55. Ausprunk,D.H. and Folkman,J. (1977) Migration and proliferation of endothelial cells in preformed and newly formed blood vessels during tumor angiogenesis. Microvasc. Res., 14, 53-65.
56. Diaz-Flores,L., Gutierrez,R. and Varela,H. (1994) Angiogenesis: an update. Histol. Histopathol., 9, 807-843.
57. Kalebic,R., Garbisa,S., Glaser,B. and Liotta,L. (1983) Basement membrane collagen: degradation by migrating endothelial cells. Science, 242, 1424-1427.
58. Wakui,S., Furusato,M., Ohshige,H. and Ushigome,S. (1993) Endothelial-pericyte interdigitations in rat subcutaneous disc implanted angiogenesis. Microvasc. Res., 46, 19-27.
59. Nehls,V., Denzer,K. and Drenckhahn,D. (1992) Pericyte involvement in capillary sprouting during angiogenesis in situ. Cell Tissue Res., 270, 469-474.
60. Diaz-Flores,L., Gutierrez,R., Varela,H., Rancel,N. and Valladares,F. (1991) Microvascular pericytes: a review of their morphological and functional characteristics. Histol. Histopathol., 6, 269-286.
61. RGSC (2003) Rat Genome Sequencing Consortium v3.1.
62. Watanabe,T.K., Bihoreau,M.-T., McCarthy,L.C. and Kiguwa,S.L. (1999) A radiation hybrid map of the rat genome containing 5,255 markers. Nature Genet., 22, 22-36.
63. Deng,A.Y., Jackson,C.M., Hoebee,B. and Rapp,J.P. (1997) Mapping of rat Chromosome 5 markers generated from chromosome-sorted DNA. Mamm. Genome, 8, 549-553.
64. Abdulmalek,K., Ashur,F., Ezer,N., Ye,F., Magder,S. and Hussain,S.N. (2001) Differential expression of Tie-2 receptors and angiopoietins in response to in vivo hypoxia in rats. Am. J. Physiol. Lung. Cell. Mol. Physiol., 281, L582-590.
65. Yamazaki,D., Suetsugu,S., Miki,H.,Y.,K., Nishikawa,S., Fujiwara,T., Yoshida,N. and Takenawa,T. (2003) WAVE2 is required for directed cell migration and cardiovascular development. Nature, 424, 452-456