-
1
-
-
0003025745
-
Mutagenic principle(s) in tryptophan and phenylalanine pyrolysis products
-
Sugimura,T., Kawachi,T., Nagao,M. et al. (1977) Mutagenic principle(s) in tryptophan and phenylalanine pyrolysis products, Proc. Jpn. Acad., 53, 58-61.
-
(1977)
Proc. Jpn. Acad.
, vol.53
, pp. 58-61
-
-
Sugimura, T.1
Kawachi, T.2
Nagao, M.3
-
2
-
-
0019739001
-
Metabolic aspects of the comutagenic action of norharman
-
Snyder,R., Jollow,D.J., Parke,D.V., Gibson,C.G., Kocsis,J.J. and Witmer,C.M. (eds), Plenum Press, New York and London
-
Sugimura,T., Nagao,M. and Wakabayashi,K. (1982) Metabolic aspects of the comutagenic action of norharman. In Snyder,R., Jollow,D.J., Parke,D.V., Gibson,C.G., Kocsis,J.J. and Witmer,C.M. (eds), Biological Reactive Intermediates-II, Chemical Mechanisms and Biological Effects Part B. Plenum Press, New York and London, pp. 1011-1025.
-
(1982)
Biological Reactive Intermediates-II, Chemical Mechanisms and Biological Effects
, Issue.PART B
, pp. 1011-1025
-
-
Sugimura, T.1
Nagao, M.2
Wakabayashi, K.3
-
3
-
-
0032810214
-
Quantification of the co-mutagenic β-carbolines, norharman and harman, in cigarette smoke condensates and cooked foods
-
Totsuka,Y., Ushiyama,H., Ishihara,J., Sinha,R., Goto,S., Sugimura,T. and Wakabayashi,K. (1999) Quantification of the co-mutagenic β-carbolines, norharman and harman, in cigarette smoke condensates and cooked foods. Cancer Lett., 143, 139-143.
-
(1999)
Cancer Lett.
, vol.143
, pp. 139-143
-
-
Totsuka, Y.1
Ushiyama, H.2
Ishihara, J.3
Sinha, R.4
Goto, S.5
Sugimura, T.6
Wakabayashi, K.7
-
4
-
-
85008095774
-
Norharman and harman in human urine
-
Ushiyama,H., Oguri,A., Totsuka,Y., Itoh,H., Sugimura,T. and Wakabayashi,K. (1995) Norharman and harman in human urine. Proc. Jpn. Acad., 71B, 57-60.
-
(1995)
Proc. Jpn. Acad.
, vol.71 B
, pp. 57-60
-
-
Ushiyama, H.1
Oguri, A.2
Totsuka, Y.3
Itoh, H.4
Sugimura, T.5
Wakabayashi, K.6
-
5
-
-
84954917540
-
Demonstration of mutagenicity of aniline and o-toluidine by norharman
-
Nagao,M., Yahagi,T., Honda,M., Seino,Y., Matsushima,T. and Sugimura,T. (1977) Demonstration of mutagenicity of aniline and o toluidine by norharman. Proc. Japan Acad., 53B, 34-37.
-
(1977)
Proc. Japan Acad.
, vol.53 B
, pp. 34-37
-
-
Nagao, M.1
Yahagi, T.2
Honda, M.3
Seino, Y.4
Matsushima, T.5
Sugimura, T.6
-
6
-
-
0027246519
-
Primary aromatic amines from side-stream cigarette smoke are common contaminants of indoor air
-
Luceri,F., Giuseppe,P., Moneti,G. and Dolara,P. (1993) Primary aromatic amines from side-stream cigarette smoke are common contaminants of indoor air. Toxicol. Ind. Health, 9, 405-413.
-
(1993)
Toxicol. Ind. Health
, vol.9
, pp. 405-413
-
-
Luceri, F.1
Giuseppe, P.2
Moneti, G.3
Dolara, P.4
-
7
-
-
0020124165
-
Aniline and aniline hydrochloride
-
International Agency for Research on Cancer (IARC) IARC, IARC Scientific Publication, Lyon
-
International Agency for Research on Cancer (IARC) (1982). Aniline and aniline hydrochloride. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. IARC, IARC Scientific Publication, Lyon, 27, 39-61.
-
(1982)
IARC Monographs on the Evaluation of Carcinogenic Risks to Humans
, vol.27
, pp. 39-61
-
-
-
8
-
-
0029591652
-
Biomonitoring of urinary aromatic amines and arylamine hemoglobin adducts in exposed workers and nonexposed control persons
-
Riffelmann,M., Muller,G., Schmieding,W., Popp,W. and Norpoth,K. (1995) Biomonitoring of urinary aromatic amines and arylamine hemoglobin adducts in exposed workers and nonexposed control persons. Int. Arch. Occup. Environ. Health, 68, 36-43.
-
(1995)
Int. Arch. Occup. Environ. Health
, vol.68
, pp. 36-43
-
-
Riffelmann, M.1
Muller, G.2
Schmieding, W.3
Popp, W.4
Norpoth, K.5
-
9
-
-
0032964930
-
Detection of monocyclic aromatic amines, possible mammary carcinogenesis, in human milk
-
DeBruin,L.S., Pawliszyn,J.B. and Josephy,P.D. (1999) Detection of monocyclic aromatic amines, possible mammary carcinogenesis, in human milk. Chem. Res. Toxicol., 12, 78-82.
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 78-82
-
-
DeBruin, L.S.1
Pawliszyn, J.B.2
Josephy, P.D.3
-
10
-
-
0022835774
-
Identification and quantitative determination of aniline and toluidines in human urine
-
Bayoumy,K.E., Donahue,J.M., Hecht,S.S. and Hoffmann,D. (1986) Identification and quantitative determination of aniline and toluidines in human urine. Cancer Res., 46, 6064-6067.
-
(1986)
Cancer Res.
, vol.46
, pp. 6064-6067
-
-
Bayoumy, K.E.1
Donahue, J.M.2
Hecht, S.S.3
Hoffmann, D.4
-
11
-
-
0031784056
-
Structural determination of a mutagenic aminophenylnorharman produced by the co-mutagen norharman with aniline
-
Totsuka,Y., Hada,N., Matsumoto,K., Kawahara,N., Murakami,Y., Yokoyama,Y., Sugimura,J. and Wakabayashi,K. (1998) Structural determination of a mutagenic aminophenylnorharman produced by the co-mutagen norharman with aniline. Carcinogenesis, 19, 1995-2000.
-
(1998)
Carcinogenesis
, vol.19
, pp. 1995-2000
-
-
Totsuka, Y.1
Hada, N.2
Matsumoto, K.3
Kawahara, N.4
Murakami, Y.5
Yokoyama, Y.6
Sugimura, J.7
Wakabayashi, K.8
-
12
-
-
0032444385
-
A new concept of co-mutagenicity from a phenomenon forgotten for the past two decades: Is it more important than previously expected?
-
Sugimura,T. (1998) A new concept of co-mutagenicity from a phenomenon forgotten for the past two decades: is it more important than previously expected? Environ. Health Perspect., 106, A522-A523.
-
(1998)
Environ. Health Perspect.
, vol.106
-
-
Sugimura, T.1
-
13
-
-
1242283918
-
Mutagens formed from β-carboline with aromatic amines
-
Totsuka,Y., Takamura-enya,T., Nishigaki,R., Sugimura,T. and Wakabayashi,K. (2004) Mutagens formed from β-carboline with aromatic amines. J. Chromatogr. B, 802, 135-141.
-
(2004)
J. Chromatogr. B
, vol.802
, pp. 135-141
-
-
Totsuka, Y.1
Takamura-Enya, T.2
Nishigaki, R.3
Sugimura, T.4
Wakabayashi, K.5
-
14
-
-
0036802093
-
Structure of DNA adduct formed with aminophenylnorharman, being responsible for the comutagenic action of norharman with aniline
-
Totsuka,Y., Takamura-Enya,T., Kawahara,N., Nishigaki,R., Sugimura,T. and Wakabayashi,K. (2002) Structure of DNA adduct formed with aminophenylnorharman, being responsible for the comutagenic action of norharman with aniline. Chem. Res. Toxicol., 15, 1288-1294.
-
(2002)
Chem. Res. Toxicol.
, vol.15
, pp. 1288-1294
-
-
Totsuka, Y.1
Takamura-Enya, T.2
Kawahara, N.3
Nishigaki, R.4
Sugimura, T.5
Wakabayashi, K.6
-
15
-
-
0037170701
-
Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline
-
Ohe,T., Takata,T., Maeda,Y., Totsuka,Y., Hada,N., Matsuoka,A., Tanaka,N. and Wakabayashi,K. (2002) Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline. Mutat. Res. 515, 181-188.
-
(2002)
Mutat. Res.
, vol.515
, pp. 181-188
-
-
Ohe, T.1
Takata, T.2
Maeda, Y.3
Totsuka, Y.4
Hada, N.5
Matsuoka, A.6
Tanaka, N.7
Wakabayashi, K.8
-
16
-
-
0037201541
-
In vitro and in vivo formation of aminophenyl-norharman from norharman and aniline
-
Totsuka,Y., Kataoka,H., Takamura-Enya,T., Sugimura,T. and Wakabayashi,K. (2002) In vitro and in vivo formation of aminophenyl-norharman from norharman and aniline. Mutat. Res., 506-507, 49-54.
-
(2002)
Mutat. Res.
, vol.506-507
, pp. 49-54
-
-
Totsuka, Y.1
Kataoka, H.2
Takamura-Enya, T.3
Sugimura, T.4
Wakabayashi, K.5
-
17
-
-
0035952366
-
Induction of liver preneoplastic lesions by aminophenylnorharman, formed from norharman and aniline, in male F344 rats
-
Kawamori,T., Totsuka,Y., Ishihara,J., Uchiya,N., Sugimura,T. and Wakabayashi,K. (2001) Induction of liver preneoplastic lesions by aminophenylnorharman, formed from norharman and aniline, in male F344 rats. Cancer Lett., 163, 157-161.
-
(2001)
Cancer Lett.
, vol.163
, pp. 157-161
-
-
Kawamori, T.1
Totsuka, Y.2
Ishihara, J.3
Uchiya, N.4
Sugimura, T.5
Wakabayashi, K.6
-
18
-
-
6444238739
-
-
(eds) Academic Press, Inc., San Diego
-
Boorman,G. A., Eustis,S. L., Elwell,M. R., Montgomery,J. C.A. and MacKenzie,W. F. (eds) (1990) Pathology of the Fischer Rat. Academic Press, Inc., San Diego, pp. 1-553.
-
(1990)
Pathology of the Fischer Rat
, pp. 1-553
-
-
Boorman, G.A.1
Eustis, S.L.2
Elwell, M.R.3
Montgomery, J.C.A.4
MacKenzie, W.F.5
-
19
-
-
0025893907
-
Mutational activation of c-Ha-ras gene in squamous cell carcinomas of rat Zymbal gland induced by carcinogenic heterocyclic amines
-
Kudo,M., Ogura,T., Esumi,H. and Sugimura,T. (1991) Mutational activation of c-Ha-ras gene in squamous cell carcinomas of rat Zymbal gland induced by carcinogenic heterocyclic amines. Mol. Carcinogen. 4, 36-47.
-
(1991)
Mol. Carcinogen.
, vol.4
, pp. 36-47
-
-
Kudo, M.1
Ogura, T.2
Esumi, H.3
Sugimura, T.4
-
20
-
-
0027261126
-
High frequency and low specificity of ras gene mutations in rat Zymbal's gland tumors induced by 2-amino-3-methylimidazo[4,5-fquinoline
-
Takahashi,M., Minamoto,T., Sugimura,T. and Esumi,H. (1993) High frequency and low specificity of ras gene mutations in rat Zymbal's gland tumors induced by 2-amino-3-methylimidazo[4,5-fquinoline. Carcinogenesis, 14, 1355-1357.
-
(1993)
Carcinogenesis
, vol.14
, pp. 1355-1357
-
-
Takahashi, M.1
Minamoto, T.2
Sugimura, T.3
Esumi, H.4
-
21
-
-
0031984227
-
Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors
-
Takahashi,M., Fukuda,K., Sugimura,T. and Wakabayashi,K. (1998) Beta-catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Res., 58, 42-46.
-
(1998)
Cancer Res.
, vol.58
, pp. 42-46
-
-
Takahashi, M.1
Fukuda, K.2
Sugimura, T.3
Wakabayashi, K.4
-
22
-
-
0032915961
-
Rare mutations of p53, Ki-ras and beta-catenin genes and absence of K-sam and c-erbB-2 amplification in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach cancers
-
Hirayama,Y., Wakazono,K., Yamamoto,M., Kitano,M., Tatematsu,M., Nagao,M., Sugimura,T. and Ushijima,T. (1999) Rare mutations of p53, Ki-ras and beta-catenin genes and absence of K-sam and c-erbB-2 amplification in N-methyl-N'-nitro-N-nitrosoguanidine-induced rat stomach cancers. Mol. Carcinogenesis, 25, 42-47.
-
(1999)
Mol. Carcinogenesis
, vol.25
, pp. 42-47
-
-
Hirayama, Y.1
Wakazono, K.2
Yamamoto, M.3
Kitano, M.4
Tatematsu, M.5
Nagao, M.6
Sugimura, T.7
Ushijima, T.8
-
23
-
-
0028878974
-
Specific 5′-GGGA-3′- > 5′-GGA-3′ mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
-
Kakiuchi,H., Watanabe,M., Ushijima,T., Toyota,M., Imai,K., Weisburger,J. H., Sugimura,T. and Nagao,M. (1995) Specific 5′-GGGA-3′- > 5′-GGA-3′ mutation of the Apc gene in rat colon tumors induced by 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine. Proc. Natl Acad. Sci. USA, 92, 910-914.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 910-914
-
-
Kakiuchi, H.1
Watanabe, M.2
Ushijima, T.3
Toyota, M.4
Imai, K.5
Weisburger, J.H.6
Sugimura, T.7
Nagao, M.8
-
24
-
-
0036200869
-
Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in combination with a high fat diet
-
Ubagai,T., Ochiai,M., Kawamori,T., Imai,H., Sugimura,T., Nagao,M. and Nakagama,H. (2002) Efficient induction of rat large intestinal tumors with a new spectrum of mutations by intermittent administration of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in combination with a high fat diet. Carcinogenesis, 23, 197-200.
-
(2002)
Carcinogenesis
, vol.23
, pp. 197-200
-
-
Ubagai, T.1
Ochiai, M.2
Kawamori, T.3
Imai, H.4
Sugimura, T.5
Nagao, M.6
Nakagama, H.7
-
25
-
-
0032873901
-
β-Catenin (Ctnnb1) gene mutations in diethylnitrosamine (DEN)-induced liver tumors in male F344 rats
-
Yamashita,Y., Yoshimi,N., Sugie,S., Suzui,S., Matsunaga,K., Kawabata,K., Hara,A. and Mori,H. (1999) β-Catenin (Ctnnb1) gene mutations in diethylnitrosamine (DEN)-induced liver tumors in male F344 rats. Jpn. J. Cancer Res., 90, 824-828.
-
(1999)
Jpn. J. Cancer Res.
, vol.90
, pp. 824-828
-
-
Yamashita, Y.1
Yoshimi, N.2
Sugie, S.3
Suzui, S.4
Matsunaga, K.5
Kawabata, K.6
Hara, A.7
Mori, H.8
-
26
-
-
0033566982
-
Different frequencies and patterns of β-catenin mutations in hepatocellular carcinomas induced by N-nitrosodiethylamine and a choline-deficient 1-amino acid-deficient diet in rats
-
Tsujiuchi,T., Tsutsumi,M., Sasaki,Y., Takahama,M. and Konishi,Y. (1999) Different frequencies and patterns of β-catenin mutations in hepatocellular carcinomas induced by N nitrosodiethylamine and a choline-deficient 1-amino acid-deficient diet in rats. Cancer Res., 59, 3904-3907.
-
(1999)
Cancer Res.
, vol.59
, pp. 3904-3907
-
-
Tsujiuchi, T.1
Tsutsumi, M.2
Sasaki, Y.3
Takahama, M.4
Konishi, Y.5
-
27
-
-
0033387207
-
Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma
-
Kondo,Y., Kanai,Y., Sakamoto,M., Genda,T., Mizokami,M., Ueda,R. and Hirohashi,S. (1999) Beta-catenin accumulation and mutation of exon 3 of the beta-catenin gene in hepatocellular carcinoma. Jpn. J. Cancer Res., 90, 1301-1309.
-
(1999)
Jpn. J. Cancer Res.
, vol.90
, pp. 1301-1309
-
-
Kondo, Y.1
Kanai, Y.2
Sakamoto, M.3
Genda, T.4
Mizokami, M.5
Ueda, R.6
Hirohashi, S.7
-
28
-
-
0032521538
-
High frequency of β-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat
-
Dashwood,R.H., Suzui,M., Nakagama,H., Sugimura,T. and Nagao,M. (1998) High frequency of β-catenin (ctnnb1) mutations in the colon tumors induced by two heterocyclic amines in the F344 rat. Cancer Res., 58, 1127-1129.
-
(1998)
Cancer Res.
, vol.58
, pp. 1127-1129
-
-
Dashwood, R.H.1
Suzui, M.2
Nakagama, H.3
Sugimura, T.4
Nagao, M.5
-
29
-
-
0030054532
-
Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis and sporadic colon cancer
-
Konishi,M., Kikuchi-Yanoshita,R., Tanaka,K. et al. (1996) Molecular nature of colon tumors in hereditary nonpolyposis colon cancer, familial polyposis and sporadic colon cancer. Gastroenterology 111, 307-317.
-
(1996)
Gastroenterology
, vol.111
, pp. 307-317
-
-
Konishi, M.1
Kikuchi-Yanoshita, R.2
Tanaka, K.3
-
30
-
-
0346258289
-
Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse
-
Masumura,K., Totsuka,Y., Wakabayashi,K. and Nohmi,T. (2003) Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse. Carcinogenesis, 24, 1985-1993.
-
(2003)
Carcinogenesis
, vol.24
, pp. 1985-1993
-
-
Masumura, K.1
Totsuka, Y.2
Wakabayashi, K.3
Nohmi, T.4
-
31
-
-
0005263849
-
Carcinogenicity in rats of a mutagenic compound, 2-amino-3, 8-dimethylimidazo[4,5-fquinoxaline
-
Kato,T., Ohgaki,H., Hasegawa,H., Sato,S., Takayama,S. and Sugimura,T. (1988) Carcinogenicity in rats of a mutagenic compound, 2-amino-3, 8-dimethylimidazo[4,5-fquinoxaline. Carcinogenesis 9, 71-73.
-
(1988)
Carcinogenesis
, vol.9
, pp. 71-73
-
-
Kato, T.1
Ohgaki, H.2
Hasegawa, H.3
Sato, S.4
Takayama, S.5
Sugimura, T.6
-
32
-
-
0018104729
-
Differences in effects of norharman with various classes of chemical mutagens and amounts of S-9
-
Nagao,M., Yahagi,T. and Sugimura,T. (1978) Differences in effects of norharman with various classes of chemical mutagens and amounts of S-9. Biochem. Biophys. Res. Commun., 83, 373-378.
-
(1978)
Biochem. Biophys. Res. Commun.
, vol.83
, pp. 373-378
-
-
Nagao, M.1
Yahagi, T.2
Sugimura, T.3
-
33
-
-
0035958284
-
Structures of mutagens produced by the co-mutagen norharman with o- and m-toluidine isomers
-
Hada,N., Totsuka,Y., Enya,T., Tsurumaki,K., Nakazawa,M., Kawahara,N., Murakami,Y., Yokoyama,Y., Sugimura,T. and Wakabayashi,K. (2001) Structures of mutagens produced by the co-mutagen norharman with o- and m-toluidine isomers. Mutat. Res., 493, 115-126.
-
(2001)
Mutat. Res.
, vol.493
, pp. 115-126
-
-
Hada, N.1
Totsuka, Y.2
Enya, T.3
Tsurumaki, K.4
Nakazawa, M.5
Kawahara, N.6
Murakami, Y.7
Yokoyama, Y.8
Sugimura, T.9
Wakabayashi, K.10
|