Hierarchical starch-based fibrous scaffold for bone tissue engineering applications

Journal of Tissue Engineering and Regenerative Medicine

Volumn 3, Issue 1, 2009, Pages 37-42

  Martins, Albino ^a,b   Chung, Sangwon ^a,b   Pedro, Adriano J ^a,b   Sousa, Rui A ^a,b,c   Marques, Alexandra P ^a,b   Reis, Rui L ^a,b,c   Neves, Nuno M ^a,b  

^a UNIVERSITY OF MINHO   (Portugal)

^b Zona Industrial da Gandra   (Portugal)

^c Stemmatters Biotechnology and Regenerative Medicine Ltd   (Portugal)

Author keywords

Bioreactor; Electrospinning; Human osteoblastic cells; Micro nano multilayer scaffolds; Rapid prototyping; Starch based fibres

Indexed keywords

BONE; CELL PROLIFERATION; ELECTROSPINNING; MULTILAYERS; NANOFIBERS; PHOSPHATASES; RAPID PROTOTYPING; SCAFFOLDS (BIOLOGY);

BIOREACTOR; BONE TISSUE ENGINEERING; FIBROUS SCAFFOLDS; HUMAN OSTEOBLASTIC CELL; MICRO/NANO MULTILAYER SCAFFOLDS; OSTEOBLASTIC CELLS; RAPID-PROTOTYPING; STARCH BASED FIBERS; STARCH-BASED; TISSUE ENGINEERING APPLICATIONS;

SCANNING ELECTRON MICROSCOPY;

ALKALINE PHOSPHATASE; BIOMATERIAL; NANOFIBER; NANOMATERIAL; POLYCAPROLACTONE; STARCH; TISSUE SCAFFOLD; DNA;

ARTICLE; BONE TISSUE; CELL ACTIVITY; CELL ADHESION; CELL PROLIFERATION; CELL SPREADING; HUMAN; HUMAN CELL; OSTEOBLAST; PRIORITY JOURNAL; TISSUE ENGINEERING; TISSUE STRUCTURE; BONE; CELL LINE; CELL SURVIVAL; CYTOLOGY; METABOLISM; MICRO-COMPUTED TOMOGRAPHY; SCANNING ELECTRON MICROSCOPY; TRANSPLANTATION; ULTRASTRUCTURE;

ALKALINE PHOSPHATASE; BONE AND BONES; CELL ADHESION; CELL LINE; CELL SURVIVAL; DNA; HUMANS; MICROSCOPY, ELECTRON, SCANNING; OSTEOBLASTS; STARCH; TISSUE ENGINEERING; TISSUE SCAFFOLDS; X-RAY MICROTOMOGRAPHY;

EID: 64349104489     PISSN: 19326254     EISSN: 19327005     Source Type: Journal    
DOI: 10.1002/term.132     Document Type: Article

References (33)

1. Agrawal CM, Ray RB. 2001; Biodegradable polymeric scaffolds for musculoskeletal tissue engineering. J Biomed Mater Res 55: 141-150.
2. Araújo JV, Martins A, Leonor IB, et al. 2008; Surface controlled biomimetic coating of polycaprolactone nanofibre meshes to be used as bone extracellular matrix analogues. J Biomater Sci Polym Ed 19: 1239-1256.
3. Capes JS, Ando HY, Cameron RE. 2005; Fabrication of polymeric scaffolds with a controlled distribution of pores. J Mater Sci Mater Med 16: 1069-1075.
4. Gomes ME, Azevedo HS, Moreira AR, et al. 2008; Starch-poly(ε-caprolactone) and starch-poly(lactic acid) fibre-mesh scaffolds for bone tissue engineering applications: structure, mechanical properties and degradation behaviour. J Tissue Eng Regen Med 2: 243-252.
5. Gomes ME, Holtorf HL, Reis RL, et al. 2006; Influence of the porosity of starch-based fibre mesh scaffolds on the proliferation and osteogenic differentiation of bone marrow stromal cells cultured in a flow perfusion bioreactor. Tissue Eng 12: 801-809.
6. Gomes ME, Reis RL, Cunha AM, et al. 2001; Cytocompatibility and response of osteoblastic-like cells to starch-based polymers: effect of several additives and processing conditions. Biomaterials 22: 1911-1917.
7. Gomes ME, Sikavitsas VI, Behravesh E, et al. 2003; Effect of flow perfusion on the osteogenic differentiation of bone marrow stromal cells cultured on starch-based three-dimensional scaffolds. J Biomed Mater Res A 67: 87-95.
8. Huang ZM, Zhang YZ, Kotaki M, et al. 2003; A review on polymer nanofibres by electrospinning and their applications in nanocomposites. Compos Sci Technol 63: 2223-2253.
9. Hutmacher DW, Schantz JT, Lam CX, et al. 2007; State of the art and future directions of scaffold-based bone engineering from a biomaterials perspective. J Tissue Eng Regen Med 1: 245-260.
10. Hutmacher DW, Sittinger M, Risbud MV. 2004; Scaffold-based tissue engineering: rationale for computer-aided design and solid freeform fabrication systems. Trends Biotechnol 22: 354-362.
11. Kwon IK, Kidoaki S, Matsuda T. 2005; Electrospun nano- to microfibre fabrics made of biodegradable copolyesters: structural characteristics, mechanical properties and cell adhesion potential. Biomaterials 26: 3929-3939.
12. Lam CXF, Mo XM, Teoh SH, et al. 2002; Scaffold development using 3D printing with a starch-based polymer. Mater Sci Eng C 20: 49-56.
13. Leong KF, Cheah CM, Chua CK. 2003; Solid freeform fabrication of three-dimensional scaffolds for engineering replacement tissues and organs. Biomaterials 24: 2363-2378.
14. Lutolf MP, Hubbell JA. 2005; Synthetic biomaterials as instructive extracellular microenvironments for morphogenesis in tissue engineering. Nature Biotechnol 23: 47-55.
15. Martins A, Araújo JV, Reis RL, et al. 2007; Electrospun nanostructured scaffolds for tissue engineering applications. Nanomedicine 2: 929-942.
16. Mironov V, Boland T, Trusk T, et al. 2003; Organ printing: computeraided jet-based 3D tissue engineering. Trends Biotechnol 21: 157-161.
17. Moroni L, de Wijn JR, van Blitterswijk CA. 2005; Three-dimensional fibre-deposited PEOT/PBT copolymer scaffolds for tissue engineering: influence of porosity, molecular network mesh size, and swelling in aqueous media on dynamic mechanical properties. J Biomed Mater Res A 75: 957-965.
18. Moroni L, de Wijn JR, van Blitterswijk CA. 2006; 3D fibre-deposited scaffolds for tissue engineering: influence of pores geometry and architecture on dynamic mechanical properties. Biomaterials 27: 974-985.
19. Moroni L, Schotel R, Hamann D, et al. 2008; 3D fibre-deposited electrospun integrated scaffolds enhance cartilage tissue formation. Adv Func Mater 18: 53-60.
20. Norman JJ, Desai TA. 2006; Methods for fabrication of nanoscale topography for tissue engineering scaffolds. Ann Biomed Eng 34: 89-101.
21. Oliveira JT, Crawford A, Mundy JM, et al. 2007; A cartilage tissue engineering approach combining starch-polycaprolactone fibre mesh scaffolds with bovine articular chondrocytes. J Mater Sci Mater Med 18: 295-302.
22. Peltola SM, Melchels FP, Grijpma DW, et al. 2008; A review of rapid prototyping techniques for tissue engineering purposes. Ann Med 40: 268-280.
23. Pfister A, Landers R, Laib A, et al. 2004; Biofunctional rapid prototyping for tissue-engineering applications: 3D bioplotting versus 3D printing. J Polym Sci Part A Polym Chem 42: 624-638.
24. Salgado AJ, Coutinho OP, Reis RL. 2004; Novel starch-based scaffolds for bone tissue engineering: cytotoxicity, cell culture, and protein expression. Tissue Eng 10: 465-474.
25. Salgado AJ, Coutinho OP, Reis RL, et al. 2007; In vivo response to starch-based scaffolds designed for bone tissue engineering applications. J Biomed Mater Res A 80: 983-989.
26. Salgado AJ, Figueiredo JE, Coutinho OP, et al. 2005; Biological response to pre-mineralized starch based scaffolds for bone tissue engineering. J Mater Sci Mater Med 16: 267-275.
27. Santos MI, Fuchs S, Gomes ME, et al. 2007; Response of micro- and macrovascular endothelial cells to starch-based fibre meshes for bone tissue engineering. Biomaterials 28: 240-248.
28. Schantz JT, Teoh SH, Lim TC, et al. 2003; Repair of calvarial defects with customized tissue-engineered bone grafts I. Evaluation of osteogenesis in a three-dimensional culture system. Tissue Eng 9: S113-126.
29. Tuzlakoglu K, Bolgen N, Salgado AJ, et al. 2005; Nano- and micro-fibre combined scaffolds: a new architecture for bone tissue engineering. J Mater Sci Mater Med 16: 1099-1104.
30. Yang F, Murugan R, Wang S, et al. 2005; Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibres and their potential in neural tissue engineering. Biomaterials 26: 2603-2610.
31. Yang S, Leong KF, Du Z, et al. 2002; The design of scaffolds for use in tissue engineering. Part II. Rapid prototyping techniques. Tissue Eng 8: 1-11.
32. Yeong WY, Chua CK, Leong KF, et al. 2004; Rapid prototyping in tissue engineering: challenges and potential. Trends Biotechnol 22: 643-652.
33. Zhang YZ, Lim CT, Ramakrishna S, et al. 2005; Recent development of polymer nanofibres for biomedical and biotechnological applications. J Mater Sci Mater Med 16: 933-946.