Facile synthesis of 4,5-disubstituted-3(2H)-pyridazinones

Tetrahedron Letters

Volumn 50, Issue 22, 2009, Pages 2682-2684

  Humphries, Paul S ^a   Oliver, Robert M ^a  

^a PFIZER INC   (United States)

Author keywords

Pyridazinone

Indexed keywords

3 (2H) PYRIDAZINONE DERIVATIVE; ALCOHOL DERIVATIVE; ALKOXIDE; BROMIDE; COPPER; IODIDE; PYRIDAZINONE DERIVATIVE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; CATALYSIS; CONTROLLED STUDY; SYNTHESIS;

EID: 64249126687     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.03.144     Document Type: Article

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11. 6) δ 12.94 (s, 1H), 8.38 (d, J = 4.7 Hz, 2H), 7.80 (s, 1H), 6.66 (t, J = 4.7 Hz, 1H), 3.86-3.83 (m, 4H), 3.43-3.41 (m, 4H). ESIMS (m/z): 338 (M+H).
12. 6) δ 8.38 (d, J = 4.8 Hz, 2H), 7.86 (s, 1H), 6.66 (t, J = 4.8 Hz, 1H), 3.90 (d, J = 7.05 Hz, 2H), 3.87-3.84 (m, 4H), 3.44-3.41 (m, 4H), 1.20 (m, 1H), 0.45 (m, 2H), 0.33 (m, 2H). ESIMS (m/z): 392 (M+H).
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