Novel formation of 1,3-oxazepine heterocycles via palladium-catalyzed intramolecular coupling reaction

Tetrahedron

Volumn 62, Issue 38, 2006, Pages 9002-9009

  Ma, Chen ^a   Liu, Shao Jie ^a   Xin, Liang ^a   Falck, J R ^b   Shin, Dong Soo ^c  

^a SHANDONG UNIVERSITY   (China)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c Changwon National University   (South Korea)

Author keywords

Intramolecular coupling; Oxazepine; Palladium catalyst; Synthesis

Indexed keywords

10 DIETHYLAMINO 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 10 DIETHYLAMINO 9 ETHYL 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 10 METHOXY 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 10 METHOXY 9 METHYL 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 10 METHOXY 9,11 DIMETHYL 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 3 (TETRAHYDROPYRAN 2 YL) 6,6A,10,11,14,15 HEXAHYDRO 3H 5,7,9,12 TETRAOXA 2,3,15A TRIAZACYCLOHEPTA[1,2 A;4,5 B']DINAPHTHALEN 4 ONE; 4 (2 BROMO 3,4,5 TRIMETHOXYPHENETHYL) 3,4 DIHYDRO 7 (TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 4 (2 BROMO 4 CHLORO 5 METHOXYPHENETHYL) 3,4 DIHYDRO 7 TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 4 (2 BROMO 4,5 DIMETHOXYPHENETHYL) 3,4 DIHYDRO 7 (TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 4 (2 BROMO 4,5 DIMETHOXYPHENETHYL) 7 (TETRAHYDRO 2H PYRAN 2 YL) 2H PYRIDAZINO[4,5 B][1,4]OXAZINE 3,8(4H,7H) DIONE; 4 (2 BROMO 5 METHOXY 4 METHYLPHENETHYL) 3,4 DIHYDRO 7 (TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 4 (2 BROMO 5 METHOXYPHENETHYL) 3,4 DIHYDRO 7 (TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 4 (3,4 DIMETHOXYPHENETHYL) 7 (TETRAHYDRO 2H PYRAN 2 YL) 2H PYRIDAZINO[4,5 B][1,4]OXAZINE 3,8(4H,7H) DIONE; 4 (6 BROMO 3 METHOXY 2,4 DIMETHYLPHENETHYL) 3,4 DIHYDRO 7 (TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]AXOZIN 8(7H) ONE; 4 [2 (5 BROMOBENZO[D][1,3]DIOXOL 6 YL)ETHYL] 3,4 DIHYDRO 7 (TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 4 [2 (6 BROMO 2,3 DIHYDROBENZO[B][1,4]DIOXIN 7 YL)ETHYL] 3,4 DIHYDRO 7 (TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 4 [2 BROMO 5 (DIETHYLAMINO) 4 ETHYLPHENETHYL] 3,4 DIHYDRO 7 TETRAHYDRO 2H PYRAN 2 YL) 3 HYDROXY 2H PYRIDAZINO[4,5 B][1,4]OXAZIN 8(7H) ONE; 8,9,10 TRIMETHOXY 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 9 CHLORO 10 METHOXY 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 9,10 DIMETHOXY 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13 TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; 9,10 METHYLENEDIOXY 3 (TETRAHYDROPYRAN 2 YL) 6,6A,12,13,TETRAHYDRO 3H 5,7 DIOXA 2,3,13A TRIAZABENZO[4,5]CYCLOHEPTA[1,2 A]NAPHTHALEN 4 ONE; FERROCENE DERIVATIVE; N (3,4 DIMETHOXYPHENETHYL) 2 CHLOROACETAMIDE; OXAZEPINE DERIVATIVE; PALLADIUM; POTASSIUM CARBONATE; PYRIDAZINONE DERIVATIVE; TOLUENE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CATALYST; CHEMICAL BOND; CHEMICAL REACTION KINETICS; DRUG SYNTHESIS; PRIORITY JOURNAL;

EID: 33746788517     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2006.07.009     Document Type: Article

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