Regulatory effects of Codonopsis lanceolata on gene expression of GM-CSF in macrophage-like cells

Journal of Ethnopharmacology

Volumn 123, Issue 1, 2009, Pages 185-189

  Byeon, Se Eun ^a   Lee, Yong Gyu ^a   Cho, Jae Youl ^a  

^a Kangwon National University   (South Korea)

Author keywords

Codonopsis lanceolata; GM CSF; Hematopoietic cytokines; Signaling cascades; Transcription factors

Indexed keywords

CODONOPSIS LANCEOLATA EXTRACT; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG;

ARTICLE; BLEEDING; CELL PROLIFERATION; CODONOPSIS; CODONOPSIS LANCEOLATA; CYTOKINE PRODUCTION; GENE EXPRESSION REGULATION; KOREA; MACROPHAGE ACTIVATION; NONHUMAN; REPORTER GENE; SIGNAL TRANSDUCTION; SPLEEN CELL; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; BLOTTING, WESTERN; CELL LINE; CODONOPSIS; DNA PRIMERS; DRUG EVALUATION, PRECLINICAL; GENE EXPRESSION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; MACROPHAGES; MALE; MICE; MICE, INBRED C57BL; NF-KAPPA B; RNA, MESSENGER; TRANSCRIPTION FACTOR AP-1; UP-REGULATION;

CODONOPSIS LANCEOLATA;

EID: 64249124960     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.02.014     Document Type: Article

References (16)

1. Barreda D.R., Hanington P.C., and Belosevic M. Regulation of myeloid development and function by colony stimulating factors. Developmental and Comparative Immunology 28 (2004) 509-554
2. Bradford M.M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Analytical Biochemistry 72 (1976) 248-254
3. Campa V.M., Iglesias J.M., Carcedo M.T., Rodriguez R., Riera J., Ramos S., and Lazo P.S. Polyinosinic acid induces TNF and NO production as well as NF-kappaB and AP-1 transcriptional activation in the monocyte macrophage cell line RAW 264.7. Inflammation Research 54 (2005) 328-337
4. Caron R.W., Yacoub A., Li M., Zhu X., Mitchell C., Hong Y., Hawkins W., Sasazuki T., Shirasawa S., Kozikowski A.P., Dennis P.A., Hagan M.P., Grant S., and Dent P. Activated forms of H-RAS and K-RAS differentially regulate membrane association of PI3K, PDK-1, and AKT and the effect of therapeutic kinase inhibitors on cell survival. Molecular Cancer Therapeutics 4 (2005) 257-270
5. Cho J.Y. Non-specific anti-proliferative effect of FTY720, a derivative of fungal metabolite from Iscaria sinclarii. Archives of Pharmacal Research 31 (2008) 160-166
6. Dharmananda, S., 2007. Codonopsis: medicine and food. http://www.itmonline.org/art/codonopsis.htm.
7. Fratkin, J., 2001. Chinese Herbal Patent Medicine: The Clinical Desk Reference. Shya Publications, Colorado, p. 46.
8. Hu X. Proteolytic signaling by TNFalpha: caspase activation and IkappaB degradation. Cytokine 21 (2003) 286-294
9. Kinne R.W., Brauer R., Stuhlmuller B., Palombo-Kinne E., and Burmester G.R. Macrophages in rheumatoid arthritis. Arthritis Research 2 (2000) 189-202
10. Lee Y.G., Byeon S.E., Kim J.Y., Lee J.Y., Rhee M.H., Hong S., Wu J.C., Lee H.S., Kim M.J., Cho D.H., and Cho J.Y. Immunomodulatory effect of Hibiscus cannabinus extract on macrophage functions. Journal of Ethnopharmacology 113 (2007) 62-71
11. Lee J.Y., Rhee M.H., and Cho J.Y. Novel modulatory effects of SDZ 62-434 on inflammatory events in activated macrophage-like and monocytic cells. Naunyn Schmiedebergs Archives of Pharmacology 377 (2008) 111-124
12. Nimer S.D., and Uchida H. Regulation of granulocyte-macrophage colony-stimulating factor and interleukin 3 expression. Stem Cells 13 (1995) 324-335
13. O'Neill H.C., Wilson H.L., Quah B., Abbey J.L., Despars G., and Ni K. Dendritic cell development in long-term spleen stromal cultures. Stem Cells 22 (2004) 475-486
14. Pulla R.K., Kim Y.J., Kim M.K., Senthil K.S., In J.G., and Yang D.C. Isolation of a novel dehydrin gene from Codonopsis lanceolata and analysis of its response to abiotic stresses. Biochemistry and Molecular Biology Report 41 (2008) 338-343
15. Purev M., Kim M.K., Samdan N., and Yang D.C. Isolation of a novel fructose-1,6-bisphosphate aldolase gene from Codonopsis lanceolata and analysis of the response of this gene to abiotic stresses. Molecular Biology (Mosk) 42 (2008) 206-213
16. Xu C., Shen G., Yuan X., Kim J.H., Gopalkrishnan A., Keum Y.S., Nair S., and Kong A.N. ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells. Carcinogenesis 27 (2006) 437-445