ZAK induces MMP-2 activity via JNK/p38 signals and reduces MMP-9 activity by increasing TIMP-1/2 expression in H9c2 cardiomyoblast cells

Molecular and Cellular Biochemistry

Volumn 325, Issue 1-2, 2009, Pages 69-77

  Cheng, Yi Chang ^a   Kuo, Wei Wen ^b   Wu, Hsi Chin ^a   Lai, Tung Yuan ^b   Wu, Chun Hsien ^b   Hwang, Jin Ming ^c   Wang, Wen Hong ^d   Tsai, Fuu Jen ^b   Yang, Jaw Ji ^c   Huang, Chih Yang ^b,e   Chu, Chun Hsien ^b  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^d TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^e ASIA UNIVERSITY   (Taiwan)

Author keywords

MMP 2 9; TIMP 1 2 and cardiac fibrosis; ZAK (mixed lineage protein kinase, Leucine zipper, and sterile alpha motif kinase)

Indexed keywords

GELATINASE A; LEUCINE ZIPPER AND STERILE ALPHA MOTIF KINASE; MITOGEN ACTIVATED PROTEIN KINASE 9; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME REGULATION; EXTRACELLULAR MATRIX; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HUMAN; HUMAN TISSUE; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; RAT; SCAR FORMATION;

ANIMALS; CELL LINE; IMMUNOHISTOCHEMISTRY; MAP KINASE SIGNALING SYSTEM; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MYOCARDIUM; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN KINASES; RATS; SIGNAL TRANSDUCTION; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2;

EID: 64249088350     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-008-0021-1     Document Type: Article

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