Adequacy of cerebral vascular remodeling following three weeks of hypobaric hypoxia: Examined by an integrated composite analytical model

Advances in Experimental Medicine and Biology

Volumn 411, Issue , 1997, Pages 369-376

  Lauro, Karen L ^a   LaManna, Joseph C ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN MICROCIRCULATION; CONTROLLED STUDY; HYPOBARISM; HYPOXIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE OXYGENATION;

ANIMALIA;

EID: 0030833764     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-5865-1_47     Document Type: Article

References (17)

1. Harik N., Harik S.I., LaManna J.C. On the Increased Cerebral Vascularity in Hypobaric Hypoxia: Time Course and Reversibity in Adult Rats. JCBFM Vol 15, Suppl. 1:S276, 1995.
2. Baumann R., Bauer C., and Bartels H. Influence of chronic and acute hypoxia on oxygen affinity and red cell 2,3 diphosphoglycerate of rats and guinea pigs, Resp. Physiol., 11: 135-144, 1971.
3. Harik S.I., Lust W.D., Jones S.C., Lauro K.L., Pundik S., LaManna J.C., Brain glucose metabolism in hypobaric hypoxia, J. Appl. Physiol. 79:136-140, 1995.
4. LaManna, J.C., Vendel, L.M. and Farrell, R.M. Brain adaptation to chronic hypobaric hypoxia in rats. J.Appl.Physiol. 72:2238-2243, 1992.
5. Mironov, V., Hritz, M.A., LaManna, J.C., Hudetz, A.G. and Harik, S.I. Architectural alterations in rat cerebral microvessels after hypobaric hypoxia. Brain Res. 660:73-80, 1994.
6. Hudetz, A.G., Spaulding, J.G. and Kiani, M.F. Computer simulation of cerebral microhemodynamics. Adv.Exp.Med.Biol. 248:293-304, 1989.
7. Hawkins, R.A., Mans, A.M. and Davis, D.W. Regional ketone body utilization by rat brain in starvation and diabetes. Am.J.Physiol. 250:169-178, 1986.
8. Hudetz, A.G., Greene, A.S., Feher, G., Knuese, D.E. and Cowley, A.W.J. Imaging system for three-dimensional mapping of cerebrocortical capillary networks in vivo. Microvasc.Res. 46:293-309, 1993.
9. Lübbers, D.W. Oxygen Delivery and Microcirculation in the Brain. In: Microcirculation in Circulatory Disorders, edited by Manabe, Zweifach, and Messmer, Tokyo:Springer-Verlag, 1988,p. 33-50.
10. Haynes, R. Physical basis of the dependence of blood viscosity on tube radius. Am.J.Physiol. 198:1193-1200, 1960.
11. Whitmore, R. Atheory of blood flow in small vessels. J.Appl.Physiol. 22:767-771, 1967.
12. Blum, J.J., Concentration profiles in and around capillaries. Am.J.Physiol. 198:991-998, 1960.
13. Musch, T.I., Dempsey, J.A., Smith, C.A., Mitchell, G.S. and Bateman, N.T. Metabolic acids and [H+] regulation in brain tissue during acclimatization to chronic hypoxia. J.Appl.Physiol. 55:1486-1495, 1983.
14. Siesjo, B.K. and Messeter, K. Factors determining intracellular pH. In: Ion homeostasis of the brain, edited by Siesjo, B.K. and Sorensen, S.C.,New York:Academic Press, 1970,p. 244-269.
15. Johannsson, H. and Siesjo, B.K. CBF and CMRO2 in hypoxia. Acta Physiol.Scand. 93:269-276, 1975.
16. LaManna, J.C., Light, A.I., Peretsman, S.J. and Rosenthal, M. Oxygen insufficiency during hypoxic hypoxia in rat brain cortex. Brain Res. 293:313-318, 1984.
17. Connett, R.J., Honig, C.R., Gayeski, T.E.J. and Brooks, G.A. Defining hypoxia: a systems view of VO2, glycolysis, energetics, and intracellular PO2. J.Appl.Physiol. 68:833-842, 1990.