Efficient substitution reaction from cysteine to the serine residue of glycosylated polypeptide: Repetitive peptide segment ligation strategy and the synthesis of glycosylated tetracontapeptide having acid labile sialyl-T N antigens

Journal of Organic Chemistry

Volumn 74, Issue 6, 2009, Pages 2494-2501

  Okamoto, Ryo ^a   Souma, Shingo ^a   Kajihara, Yasuhiro ^a  

^a YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACID-LABILE; AMIDE BONDS; CN-BR ACTIVATIONS; CYSTEINE RESIDUES; ESTER LINKAGES; GLYCOPEPTIDE; GLYCOPEPTIDES; GLYCOSYLATED; N TERMINALS; NATIVE CHEMICAL LIGATIONS; SERINE RESIDUES; SOLID-PHASE GLYCOPEPTIDE SYNTHESIS; SUGAR MOIETIES; TANDEM REPEATS; THIOESTER; TRIFLUOROACETIC ACIDS;

ACIDS; AMIDES; AMINES; AMINO ACIDS; ESTERS; PEPTIDES; SUBSTITUTION REACTIONS; SUGAR (SUCROSE); SUGARS;

SYNTHESIS (CHEMICAL);

CYSTEINE; GLYCOPEPTIDE; PEPTIDE; SERINE; SIALIC ACID DERIVATIVE; THIOESTER; TN ANTIGEN; TRIFLUOROACETIC ACID;

AMINO TERMINAL SEQUENCE; ARTICLE; GLYCOSYLATION; METHYLATION; PEPTIDE SYNTHESIS; SOLID PHASE SYNTHESIS; SUBSTITUTION REACTION; TANDEM REPEAT;

ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CYSTEINE; GLYCOPEPTIDES; SERINE;

EID: 64149109414     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo8026164     Document Type: Article

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