Demonstration that CobG, the monooxygenase associated with the ring contraction process of the aerobic cobalamin (vitamin B12) biosynthetic pathway, contains an Fe-S center and a mononuclear non-heme iron center

Journal of Biological Chemistry

Volumn 284, Issue 8, 2009, Pages 4796-4805

  Schroeder, Susanne ^a   Lawrence, Andrew D ^a   Biedendieck, Rebekka ^a   Rose, Ruth Sarah ^a   Deery, Evelyne ^a   Graham, Ross M ^b   McLean, Kirsty J ^c   Munro, Andrew W ^c   Rigby, Stephen E J ^c   Warren, Martin J ^a  

^a UNIVERSITY OF KENT   (United Kingdom)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^c UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; BIOSYNTHESIS; ENZYMES; IRON; IRON COMPOUNDS; PORPHYRINS;

BIOSYNTHETIC PATHWAY; COBALAMIN (VITAMIN B12); CYSTEINE RESIDUES; PINACOL REARRANGEMENTS; PSEUDOMONAS DENITRIFICANS; RING CONTRACTION; SITE DIRECTED MUTAGENESIS; TERTIARY ALCOHOLS;

SULFUR COMPOUNDS;

CYANOCOBALAMIN; DITHIONITE; NONHEME IRON PROTEIN; PROTEIN COBG; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; BACTERIAL PROTEIN; COBAMAMIDE; COBG PROTEIN, PSEUDOMONAS DENITRIFICANS; IRON; MIXED FUNCTION OXIDASE; NITRIC OXIDE; OXYGENASE; SULFUR;

AEROBIC METABOLISM; ARTICLE; BACTERIAL CELL; BIOSYNTHESIS; BRUCELLA MELITENSIS; CONTROLLED STUDY; ENZYME ACTIVITY; IN VITRO STUDY; MOLECULAR CLONING; MONONUCLEAR CELL; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PSEUDOMONAS; PSEUDOMONAS DINITRIFICANS; SITE DIRECTED MUTAGENESIS; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; OXIDATION REDUCTION REACTION; PHYSIOLOGY;

BACTERIA (MICROORGANISMS); BRUCELLA MELITENSIS; PSEUDOMONAS DENITRIFICANS;

AEROBIOSIS; BACTERIAL PROTEINS; BRUCELLA MELITENSIS; CATALYTIC DOMAIN; COBAMIDES; IRON; MIXED FUNCTION OXYGENASES; MUTAGENESIS, SITE-DIRECTED; NITRIC OXIDE; OXIDATION-REDUCTION; OXYGENASES; PSEUDOMONAS; SULFUR;

EID: 64149105244     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M807184200     Document Type: Article

References (48)

1. Minot, G. R., and Murphy, W. P. (1983) J. Am. Med. Assoc. 250, 3328-3335
2. Rickes, E. L., Brink, N. G., Koniuszy, F. R., Wood, T. R., and Folkers, K. (1948) Science 107, 396-397
3. Smith, E. L. (1948) Nature 161, 638-639
4. Hodgkin, D. C., Pickworth, J., Robertson, J. H., Trueblood, K. N., Prosen, R. J., and White, J. (1955) Nature 176, 325-328
5. Warren, M. J., Raux, E., Schubert, H. L., and Escalante-Semerena, J. C. (2002) Nat. Prod. Rep. 19, 390-412
6. Battersby, A. R. (1994) Science 264, 1551-1557
7. Blanche, F., Thibaut, D., Debussche, L., Hertle, R., Zipfel, F., and Müller, G. (1993) Angew. Chem. Int. Ed. Engl. 32, 1651-1653
8. Raux, E., Schubert, H. L., Roper, J. M., Wilson, S. W., and Warren, M. J. (1999) Bioorg. Chem. 27, 100-118
9. Roessner, C. A., Santander, P. J., and Scott, A. I. (2001) Vitam. Horm. 61, 267-297
10. Scott, A. I. (1994) Heterocycles 39, 471-476
11. Debussche, L., Thibaut, D., Cameron, B., Crouzet, J., and Blanche, F. (1993) J. Bacteriol. 175, 7430-7440
12. Scott, A. I., Roessner, C. A., Stolowich, N. J., Spencer, J. B., Min, C., and Ozaki, S. I. (1993) FEBS Lett. 331, 105-108
13. Debussche, L., Thibaut, D., Danzer, M., Debu, F., Frechet, D., Herman, F., Blanche, F., and Vuilhorgne, M. (1993) J. Chem. Soc. Chem. Commun. 1100-1103
14. Spencer, J. B., Stolowich, N. J., Roessner, C. A., Min, C. H., and Scott, A. I. (1993) J. Am. Chem. Soc. 115, 11610-11611
15. Spencer, J. B., Stolowich, N. J., Santander, P. J., Pichon, C., Kajiwara, M., Tokiwa, S., Takatori, K., and Scott, A. I. (1994) J. Am. Chem. Soc. 116, 4991-4992
16. Stolowich, N. J., Wang, J. J., Spencer, J. B., Santander, P. J., Roessner, C. A., and Scott, A. I. (1996) J. Am. Chem. Soc. 118, 1657-1662
17. Christner, J. A., Munck, E., Janick, P. A., and Siegel, L. M. (1981) J. Biol. Chem. 256, 2098-2101
18. Crane, B. R., Siegel, L. M., and Getzoff, E. D. (1995) Science 270, 59-67
19. Janick, P. A., and Siegel, L. M. (1982) Biochemistry 21, 3538-3547
20. Raux, E., Lanois, A., Levillayer, F., Warren, M. J., Brody, E., Rambach, A., and Thermes, C. (1996) J. Bacteriol. 178, 753-767
21. Dutton, P. L. (1978) Methods Enzymol. 54, 411-435
22. Munro, A. W., Noble, M. A., Robledo, L., Daff, S. N., and Chapman, S. K. (2001) Biochemistry 40, 1956-1963
23. Ost, T. W., Miles, C. S., Munro, A. W., Murdoch, J., Reid, G. A., and Chapman, S. K. (2001) Biochemistry 40, 13421-13429
24. Lovenberg, W. (1973) Iron-Sulphur Proteins, Vol II, pp. 195-237, Academic Press, New York
25. Bertini, I., Ciurli, S., and Luchinat, C. (1995) Structure and Bonding, pp. 1-53, Springer, Berlin/Heidelberg
26. Johnson, M. K., Duderstadt, R. E., and Duin, E. C. (1999) Adv. Inorg. Chem. 47, 1-82
27. Mouesca, J. M., and Lamotte, B. (1998) Coord. Chem. Rev. 180, 1573-1614
28. Bertrand, P., Gayda, J.-P., and Rao, K. K. (1982) J. Chem. Phys. 76, 4715-4719
29. Sweeney, W. V., and Rabinowitz, J. C. (1980) Annu. Rev. Biochem. 49, 139-161
30. Solomon, E. I., Brunold, T. C., Davis, M. I., Kemsley, J. N., Lee, S. K., Lehnert, N., Neese, F., Skulan, A. J., Yang, Y. S., and Zhou, J. (2000) Chem. Rev. 100, 235-350
31. Neidig, M. L., and Solomon, E. I. (2005) Chem. Comm. 5843-5863
32. Parsons, J. B., Dinesh, S. D., Deery, E., Leech, H. K., Brindley, A. A., Heldt, D., Frank, S., Smales, C. M., Lunsdorf, H., Rambach, A., Gass, M. H., Bleloch, A., McClean, K. J., Munro, A. W., Rigby, S. E., Warren, M. J., and Prentice, M. B. (2008) J. Biol. Chem. 283, 14366-14375
33. Leech, H. K., Raux, E., McLean, K. J., Munro, A. W., Robinson, N. J., Borrelly, G. P., Malten, M., Jahn, D., Rigby, S. E., Heathcote, P., and Warren, M. J. (2003) J. Biol. Chem. 278, 41900-41907
34. Girerd, J. J., Banse, F., and Simaan, A. J. (2000) Metal-Oxo and Metal-Peroxo Species in Catalytic Oxidations 97, 145-177
35. Simaan, A. J., Banse, F., Mialane, P., Boussac, A., Un, S., Kargar-Grisel, T., Bouchoux, G., and Girerd, J. J. (1999) Eur. J. of Inorg. Chem. 993-996
36. Burger, R. M., Peisach, J., and Horowitz, S. B. (1981) J. Biol. Chem. 256, 11636-11644
37. Simaan, A. J., Banse, F., Girerd, J. J., Wieghardt, K., and Bill, E. (2001) Inorg. Chem. 40, 6538-6540
38. Ryle, M. J., and Hausinger, R. P. (2002) Curr. Opin. Chem. Biol. 6, 193-201
39. Nelson, M. J. (1987) J. Biol. Chem. 262, 12137-12142
40. Arciero, D. M., Lipscomb, J. D., Huynh, B. H., Kent, T. A., and Münck, E. (1983) J. Biol. Chem. 258, 14981-14991
41. Chen, V. J., Orville, A. M., Harpe, M. R., Frolik, C. A., Surerus, K. K., Münck, E., and Lipscomb, J. D. (1989) J. Biol. Chem. 264, 21677-21681
42. Jackson, T. A., Yikilmaz, E., Miller, A.-F., and Brunold, T. C. (2003) J. Am. Chem. Soc. 125, 8348-8363
43. Bian, S. M., and Cowan, J. A. (1999) Coord. Chem. Rev. 192, 1049-1066
44. Gaffney, B. J. (1996) Annu. Rev. Biophys. Biomol. Struct. 25, 431-459
45. Costas, M., Mehn, M. P., Jensen, M. P., and Que, L., Jnr. (2004) Chem. Rev. 104, 939-986
46. Eschenmoser, A. (1988) Angew. Chem. 27, 5-39
47. Bartlett, G. J., Borkakoti, N., and Thornton, J. M. (2003) J. Mol. Biol. 331, 829-860
48. McGoldrick, H. M., Roessner, C. A., Raux, E., Lawrence, A. D., McLean, K. J., Munro, A. W., Santabarbara, S., Rigby, S. E., Heathcote, P., Scott, A. I., and Warren, M. J. (2005) J. Biol. Chem. 280, 1086-1094