Area at risk and viability after myocardial ischemia and reperfusion can be determined by contrast-enhanced cardiac magnetic resonance imaging

European Surgical Research

Volumn 43, Issue 1, 2009, Pages 13-23

  Vosseler, M ^a   Abegunewardene, N ^a   Hoffmann, N ^a   Petersen, S E ^c   Becker, D ^a   Cleppien, D ^a   Kunz, P ^a   Kreitner, K F ^a   Lauterbach, M ^a   Bierbach, B ^b   Duber C ^a   Gori, T ^a   Munzel T ^a   Schreiber, L M ^a   Horstick, G ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Ischemia and reperfusion; Magnetic resonance imaging; Microcirculation; Myocardial infarction; Reperfusion injury

Indexed keywords

EVANS BLUE; GADOLINIUM PENTETATE; TRIPHENYLTETRAZOLIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTRAST ENHANCEMENT; CONTROLLED STUDY; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; LEFT ANTERIOR DESCENDING CORONARY ARTERY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; RECANALIZATION; REPERFUSION INJURY; STAINING; SWINE;

ANIMALS; CELL SURVIVAL; CORONARY ANGIOGRAPHY; FEMALE; GADOLINIUM DTPA; MAGNETIC RESONANCE IMAGING; MALE; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; NECROSIS; SWINE; TISSUE SURVIVAL;

EID: 64149103084     PISSN: 0014312X     EISSN: None     Source Type: Journal    
DOI: 10.1159/000211716     Document Type: Article

References (61)

1. Selvanayagam JB, Petersen SE, Francis JM, Robson MD, Kardos A, Neubauer S, Taggart DP: Effects of off-pump versus on-pump coronary surgery on reversible and irreversible myocardial injury:a randomized trial using cardiovascular magnetic resonance imaging and biochemical markers. Circulation 2004;109:345-350.
2. Selvanayagam JB, Kardos A, Francis JM, Wiesmann F, Petersen SE, Taggart DP, Neu- bauer S: Value of delayed-enhancement cardiovascular magnetic resonance imaging in predicting myocardial viability after surgical revascularization. Circulation 2004;110:1535-1541.
3. Klein HH, Puschmann S, Schaper J, Schaper W: The mechanisms of the tetrazolium reaction in identifying experimental myocardial infarction. Virchows Arch 1981;393:287-297.
4. Hale SL, Vivaldi MT, Kloner RA: Fluorescent microspheres:a new tool for visualization of ischemic myocardium in rats. Am J Physiol 1986;251:H863-H868.
5. Horstick G, Berg O, Heimann A, Gotze O, Loos M, Hafner G, Bierbach B, Petersen S, Bhakdi S, Darius H, Horstick M, Meyer J, Kempski O:Application of C1-esterase inhibitor during reperfusion of ischemic myocardium:dose-related beneficial versus detrimental effects. Circulation 2001;104:3125-3131.
6. Junqueira LC, Bignolas G, Brentani RR: Pic- rosirius staining plus polarization microscopy, a specific method for collagen detection in tissue sections. Histochem J 1979;11:447-455.
7. Hale SL, Kloner RA:Left ventricular topographic alterations in the completely healed rat infarct caused by early and late coronary artery reperfusion. Am Heart J 1988;116:1508-1513.
8. Nawata J, Ohno I, Isoyama S, Suzuki J, Miu- ra S, Ikeda J, Shirato K: Differential expression of alpha 1, alpha 3 and alpha 5 integrin subunits in acute and chronic stages of myo- cardial infarction in rats. Cardiovasc Res 1999;43:371-381.
9. Kaul S, Ito H:Microvasculature in acute myocardial ischemia:part I: evolving concepts in pathophysiology, diagnosis, and treatment. Circulation 2004;109:146-149.
10. Kaul S, Ito H:Microvasculature in acute myocardial ischemia:part II: evolving concepts in pathophysiology, diagnosis, and treatment. Circulation 2004;109:310-315.
11. Hoffmann R, von Bardeleben S, Kasprzak JD, Borges AC, ten Cate F, Firschke C, Lafitte S, Al Saadi N, Kuntz Hehner S, Horstick G, Greis C, Engelhardt M, Vanoverschelde JL, Becher H:Analysis of regional left ventricular function by cineventriculography, cardiac magnetic resonance imaging, and unen- hanced and contrast-enhanced echocardio- graphy:a multicenter comparison of methods. J Am Coll Cardiol 2006;47:121-128.
12. Wei K, Jayaweera AR, Firoozan S, Linka A, Skyba DM, Kaul S: Quantification of myo- cardial blood flow with ultrasound-induced destruction of microbubbles administered as a constant venous infusion. Circulation 1998;97:473-483.
13. Coggins MP, Sklenar J, Le DE, Wei K, Lindner JR, Kaul S: Noninvasive prediction of ultimate infarct size at the time of acute coronary occlusion based on the extent and magnitude of collateral-derived myocardial blood flow. Circulation 2001;104:2471-2477.
14. Hansen A, Kumar A, Wolf D, Franken- bergerova K, Filusch A, Gross ML, Mueller S, Katus H, Kuecherer H:Evaluation of cardio- protective effects of recombinant soluble P- selectin glycoprotein ligand-immunoglob- ulin in myocardial ischemia-reperfusion injury by real-time myocardial contrast echocardiography. J Am Coll Cardiol 2004;44:887-891.
15. Villanueva FS, Glasheen WP, Sklenar J, Kaul S:Assessment of risk area during coronary occlusion and infarct size after reperfusion with myocardial contrast echocardiography using left and right atrial injections of contrast. Circulation 1993;88:596-604.
16. Ragosta M, Camarano G, Kaul S, Powers ER, Sarembock IJ, Gimple LW: Microvascular integrity indicates myocellular viability in patients with recent myocardial infarction. New insights using myocardial contrast echocardiography. Circulation 1994;89:2562-2569.
17. Lepper W, Hoffmann R, Kamp O, Franke A, de Cock CC, Kuhl HP, Sieswerda GT, Dahl J, Janssens U, Voci P, Visser CA, Hanrath P:Assessment of myocardial reperfusion by intravenous myocardial contrast echocardiog- raphy and coronary flow reserve after primary percutaneous transluminal coronary angioplasty in patients with acute myocar- dial infarction. Circulation 2000;101:2368-2374.
18. Judd RM, Lugo Olivieri CH, Arai M, Kondo T, Croisille P, Lima JA, Mohan V, Becker LC, Zerhouni EA: Physiological basis of myocar- dial contrast enhancement in fast magnetic resonance images of 2-day-old reperfused canine infarcts. Circulation 1995;92:1902-1910.
19. Kim RJ, Fieno DS, Parrish TB, Harris K, Chen EL, Simonetti O, Bundy J, Finn JP, Klocke FJ, Judd RM: Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation 1999;100:1992-2002.
20. Kim RJ, Wu E, Rafael A, Chen EL, Parker MA, Simonetti O, Klocke FJ, Bonow RO, Judd RM:The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. N Engl J Med 2000;343:1445-1453.
21. Garcia Dorado D, Oliveras J, Gili J, Sanz E, Perez Villa F, Barrabes J, Carreras MJ, So- lares J, Soler Soler J: Analysis of myocardial oedema by magnetic resonance imaging early after coronary artery occlusion with or without reperfusion. Cardiovasc Res 1993;27:1462-1469.
22. Schafer M, Schafer C, Ewald N, Piper HM, Noll T: Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia. Circ Res 2003;92:1010-1015.
23. Horstick G, Bierbach B, Schlindwein P, Abe- gunewardene N, Vosseler M, Bittinger F, Becker D, Lauterbach M, Lehr HA, Kempski O:Resistance of the internal mammary artery to restenosis:a histomorphologic study of various porcine arteries. J Vasc Res 2008;45:45-53.
24. Horstick G, Heimann A, Gotze O, Hafner G, Berg O, Boehmer P, Becker P, Darius H, Rup- precht HJ, Loos M, Bhakdi S, Meyer J, Kemp- ski O:Intracoronary application of C1 ester- ase inhibitor improves cardiac function and reduces myocardial necrosis in an experimental model of ischemia and reperfusion. Circulation 1997;95:701-708.
25. Schmitt M, Horstick G, Petersen SE, Karg A, Hoffmann N, Gumbrich T, Abegunewar- dene N, Schreiber WG: Quantification of resting myocardial blood flow in a pig model of acute ischemia based on first-pass MRI. Magn Reson Med 2005;53:1223-1227.
26. Petersen SE, Mohrs OK, Horstick G, Ober- holzer K, Abegunewardene N, Ruetzel K, Selvanayagam JB, Robson MD, Neubauer S, Thelen M, Meyer J, Kreitner KF:Influence of contrast agent dose and image acquisition timing on the quantitative determination of nonviable myocardial tissue using delayed contrast-enhanced magnetic resonance imaging. J Cardiovasc Magn Reson 2004;6:541-548.
27. Simonetti OP, Kim RJ, Fieno DS, Hillen brand HB, Wu E, Bundy JM, Finn JP, Judd RM: An improved MR imaging technique for the visualization of myocardial infarction. Radiology 2001;218:215-223.
28. Bland JM, Altman DG: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1986;i:307-310.
29. Kim RJ, Chen EL, Lima JA, Judd RM:Myo cardial Gd-DTPA kinetics determine MR contrast enhancement and reflect the exten and severity of myocardial injury after acut reperfused infarction. Circulation 1996;94:3318-3326.
30. Hillenbrand HB, Kim RJ, Parker MA, Fien DS, Judd RM: Early assessment of myocar dial salvage by contrast-enhanced magneti resonance imaging. Circulation 2000;102:1678-1683.
31. Rochitte CE, Lima JA, Bluemke DA, Reede SB, McVeigh ER, Furuta T, Becker LC, Meli JA: Magnitude and time course of microvas cular obstruction and tissue injury afte acute myocardial infarction. Circulatio 1998;98:1006-1014.
32. Maxwell MP, Hearse DJ, Yellon DM: Specie variation in the coronary collateral circula tion during regional myocardial ischaemia a critical determinant of the rate of evolutio and extent of myocardial infarction. Cardio vasc Res 1987;21:737-746.
33. Canty JM Jr, Fallavollita JA: Resting myocar dial flow in hibernating myocardium:vali dating animal models of human pathophysi ology. Am J Physiol 1999;277:H417-H422.
34. Hughes GC, Post MJ, Simons M, Annex BH Translational physiology:porcine models o human coronary artery disease: implication for preclinical trials of therapeutic angiogen esis. J Appl Physiol 2003;94:1689-1701.
35. Schaper W: Experimental infarcts and th microcirculation;in Hearse D, Yellon (eds): Therapeutic Approaches to Myocar dial Infarct Size Limitation. New York, Ra ven Press, 1984, pp 79-90.
36. Schaper W, Frenzel H, Hort W:Experimen tal coronary artery occlusion. I. Measure ment of infarct size. Basic Res Cardiol 1979;74:46-53.
37. Schaper W:Exerimental coronary artery oc clusion. III. The determinants of collatera blood flow in acute coronary occlusion. Ba sic Res Cardiol 1978;73:584-594.
38. Vatner SF: Correlation between acute reduc tions in myocardial blood flow and function in conscious dogs. Circ Res 1980;47:201-207.
39. Hearse DJ: Models and problems in the stud of myocardial ischemia and tissue protec tion. Eur Heart J 1983;4(suppl C):43-48.
40. Rehwald WG, Kim RJ, Simonetti OP, Laub G Judd RM: Theory of high-speed MR imagin of the human heart with the selective line ac quisition mode. Radiology 2001;220:540 547.
41. Ito WD, Schaarschmidt S, Klask R, Hanse S, Schafer HJ, Mathey D, Bhakdi S: Infarc size measurement by triphenyltetrazolium chloride staining versus in vivo injection o propidium iodide. J Mol Cell Cardiol 1997 29:2169-2175.
42. Matsumura K, Jeremy RW, Schaper J, Becke LC: Progression of myocardial necrosis dur ing reperfusion of ischemic myocardium Circulation 1998;97:795-804.
43. Oshinski JN, Yang Z, Jones JR, Mata JF, French BA: lmaging time after Gd-DTPA injection is critical in using delayed enhancement to determine infarct size accurately with magnetic resonance imaging. Circulation 2001;104:2838-2842.
44. Zhu X, Zhang R, Campagna NF, Zhao M: Assessment of reperfused myocardial infarction in the hyper-acute phase with delayed enhancement magnetic resonance imaging. J Cardiovasc Magn Reson 2006;8:461-467.
45. lngkanisorn WP, Rhoads KL, Aletras AH, Kellman P, Arai AE:Gadolinium delayed enhancement cardiovascular magnetic resonance correlates with clinical measures of myocardial infarction. J Am Coll Cardiol 2004;43:2253-2259.
46. Weis S, Shintani S, Weber A, Kirchmair R, Wood M, Cravens A, McSharry H, lwakura A, Yoon YS, Himes N, Burstein D, Doukas J, Soll R, Losordo D, Cheresh D:Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocar- dial infarction. J Clin lnvest 2004;113:885-894.
47. Arheden H, Saeed M, Higgins CB, Gao DW, Ursell PC, Bremerich J, Wyttenbach R, Dae MW, Wendland MF:Reperfused rat myocardium subjected to various durations of ischemia:estimation of the distribution volume of contrast material with echo-planar MR imaging. Radiology 2000;215:520-528.
48. Friedrich MG, Abdel Aty H, Taylor A, Schulz Menger J, Messroghli D, Dietz R: The salvaged area at risk in reperfused acute myo- cardial infarction as visualized by cardiovascular magnetic resonance. J Am Coll Cardiol 2008;51:1581-1587.
49. Bindewald K, Gunduz D, Hartel F, Peters SC, Rodewald C, Nau S, Schafer M, Neumann J, Piper HM, Noll T: Opposite effect of cAMP signaling in endothelial barriers of different origin. Am J Physiol Cell Physiol 2004;287:C1246-C1255.
50. Saeed M, Lee RJ, Weber O, Do L, Martin A, Ursell P, Saloner D, Higgins CB:Scarred myocardium imposes additional burden on remote viable myocardium despite a reduction in the extent of area with late contrast MR enhancement. Eur Radiol 2006;16:827-836.
51. Wang Y, Sun W, Cao G, Meng L, Song L, Du X:Delayed hyperenhancement patterns in occlusive and reperfused myocardial in- farcts during different healing stages. J Magn Reson lmaging 2006;24:851-857.
52. Lima JA, Judd RM, Bazille A, Schulman SP, Atalar E, Zerhouni EA: Regional heterogeneity of human myocardial infarcts demonstrated by contrast-enhanced MRl. Potential mechanisms. Circulation 1995;92:1117-1125.
53. Wu KC, Zerhouni EA, Judd RM, Lugo-Oli- vieri CH, Barouch LA, Schulman SP, Blu- menthal RS, Lima JA: Prognostic significance of microvascular obstruction by magnetic resonance imaging in patients with acute myocardial infarction. Circulation 1998;97:765-772.
54. Wu KC, Kim RJ, Bluemke DA, Rochitte CE, Zerhouni EA, Becker LC, Lima JA:Quantification and time course of microvascular obstruction by contrast-enhanced echocar- diography and magnetic resonance imaging following acute myocardial infarction and reperfusion. J Am Coll Cardiol 1998;32:1756-1764.
55. Schmidt A, Azevedo CF, Cheng A, Gupta SN, Bluemke DA, Foo TK, Gerstenblith G, Weiss RG, Marban E, Tomaselli GF, Lima JA, Wu KC:lnfarct tissue heterogeneity by magnetic resonance imaging identifies enhanced cardiac arrhythmia susceptibility in patients with left ventricular dysfunction. Circulation 2007;115:2006-2014.
56. Amado LC, Gerber BL, Gupta SN, Rettmann DW, Szarf G, Schock R, Nasir K, Kraitchman DL, Lima JA: Accurate and objective infarct sizing by contrast-enhanced magnetic resonance imaging in a canine myocardial infarction model. J Am Coll Cardiol 2004;44:2383-2389.
57. Natanzon A, Aletras AH, Hsu LY, Arai AE: Determining canine myocardial area at risk with manganese-enhanced MR imaging. Radiology 2005;236:859-866.
58. 2-weighted cardiac magnetic resonance imaging:histopathological and displacement encoding with stimulated echoes (DENSE) functional validations. Circulation 2006;113:1865-1870.
59. Beek AM, Kuhl HP, Bondarenko O, Twisk JW, Hofman MB, van Dockum WG, Visser CA, van Rossum AC: Delayed contrast-enhanced magnetic resonance imaging for the prediction of regional functional improvement after acute myocardial infarction. J Am Coll Cardiol 2003;42:895-901.
60. lchikawa Y, Sakuma H, Suzawa N, Kitagawa K, Makino K, Hirano T, Takeda K: Late gadolinium-enhanced magnetic resonance imaging in acute and chronic myocardial infarction. lmproved prediction of regional myo- cardial contraction in the chronic state by measuring thickness of nonenhanced myocardium. J Am Coll Cardiol 2005;45:901-909.
61. Taylor AJ, Al Saadi N, Abdel Aty H, Schulz Menger J, Messroghli DR, Friedrich MG: Detection of acutely impaired microvascular reperfusion after infarct angioplasty with magnetic resonance imaging. Circulation 2004;109:2080-2085