Activation of the Hedgehog pathway in the mouse fetal ovary leads to ectopic appearance of fetal Leydig cells and female pseudohermaphroditism

Developmental Biology

Volumn 329, Issue 1, 2009, Pages 96-103

  Barsoum, Ivraym B ^a   Bingham, Nathan C ^b   Parker, Keith L ^b   Jorgensen, Joan S ^c   Yao, Humphrey H C ^d  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

Cell fate determination; Gonad; Hedgehog; Leydig cells

Indexed keywords

ANDROGEN; INSULIN LIKE GROWTH FACTOR 3; SOMATOMEDIN; SONIC HEDGEHOG PROTEIN; STEROIDOGENIC FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CONTROLLED STUDY; EMBRYO; FEMALE; FEMALE GENITAL SYSTEM; FEMALE PSEUDOHERMAPHRODITISM; FETUS; FETUS CELL; LEYDIG CELL; MOUSE; NONHUMAN; OVARY; OVARY DEVELOPMENT; PRECURSOR; PRIORITY JOURNAL; SOMATIC CELL; VIRILIZATION;

ERINACEIDAE; MAMMALIA;

EID: 64049103389     PISSN: 00121606     EISSN: 1095564X     Source Type: Journal    
DOI: 10.1016/j.ydbio.2009.02.025     Document Type: Article

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