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Volumn 7, Issue 2, 2009, Pages 165-181

Posaconazole's impact on prophylaxis and treatment of invasive fungal infections: An update

Author keywords

Antifungal prophylaxis; Azole; Fungal infection; Posaconazole; Triazole

Indexed keywords

AMPHOTERICIN B; ANTINEOPLASTIC AGENT; CALCINEURIN INHIBITOR; CASPOFUNGIN; CYCLOSPORIN; ECHINOCANDIN; FLUCONAZOLE; ITRACONAZOLE; PHENYTOIN; POSACONAZOLE; PROTON PUMP INHIBITOR; RAPAMYCIN; RIFABUTIN; TACROLIMUS; VORICONAZOLE; ANTIFUNGAL AGENT; TRIAZOLE DERIVATIVE;

EID: 64049088064     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/14787210.7.2.165     Document Type: Article
Times cited : (19)

References (115)
  • 1
    • 0031882396 scopus 로고    scopus 로고
    • Oropharyngeal and esophageal candidiasis in immunocompromised patients: Treatment issues
    • Darouiche RO. Oropharyngeal and esophageal candidiasis in immunocompromised patients: treatment issues. Clin. Infect. Dis. 26(2), 259-272 (1998).
    • (1998) Clin. Infect. Dis , vol.26 , Issue.2 , pp. 259-272
    • Darouiche, R.O.1
  • 2
    • 33746070016 scopus 로고    scopus 로고
    • Attributable mortality of candidemia: A systematic review of matched cohort and case - control studies
    • Falagas ME, Apostolou KE, Pappas VD. Attributable mortality of candidemia: a systematic review of matched cohort and case - control studies. Eur. J. Clin. Microbiol. Infect. Dis. 25(7), 419-425 (2006).
    • (2006) Eur. J. Clin. Microbiol. Infect. Dis , vol.25 , Issue.7 , pp. 419-425
    • Falagas, M.E.1    Apostolou, K.E.2    Pappas, V.D.3
  • 3
    • 0035109799 scopus 로고    scopus 로고
    • Aspergillosis case - fatality rate: Systematic review of the literature
    • Lin SJ, Schranz J, Teutsch SM. Aspergillosis case - fatality rate: systematic review of the literature. Clin. Infect. Dis. 32(3), 358-366 (2001).
    • (2001) Clin. Infect. Dis , vol.32 , Issue.3 , pp. 358-366
    • Lin, S.J.1    Schranz, J.2    Teutsch, S.M.3
  • 4
    • 23844464106 scopus 로고    scopus 로고
    • Epidemiology and outcome of zygomycosis: A review of 929 reported cases
    • Roden MM, Zaoutis TE, Buchanan WL et al. Epidemiology and outcome of zygomycosis: a review of 929 reported cases. Clin. Infect. Dis. 41(5), 634-653 (2005).
    • (2005) Clin. Infect. Dis , vol.41 , Issue.5 , pp. 634-653
    • Roden, M.M.1    Zaoutis, T.E.2    Buchanan, W.L.3
  • 5
    • 0036532203 scopus 로고    scopus 로고
    • Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients
    • Marr KA, Carter RA, Crippa F, Wald A, Corey L. Epidemiology and outcome of mould infections in hematopoietic stem cell transplant recipients. Clin. Infect. Dis. 34(7), 909-917 (2002).
    • (2002) Clin. Infect. Dis , vol.34 , Issue.7 , pp. 909-917
    • Marr, K.A.1    Carter, R.A.2    Crippa, F.3    Wald, A.4    Corey, L.5
  • 6
    • 2342455726 scopus 로고    scopus 로고
    • Fusarium infection in hematopoietic stem cell transplant recipients
    • Nucci M, Marr KA, Queiroz-Telles F et al. Fusarium infection in hematopoietic stem cell transplant recipients. Clin. Infect. Dis. 38(9), 1237-1242 (2004).
    • (2004) Clin. Infect. Dis , vol.38 , Issue.9 , pp. 1237-1242
    • Nucci, M.1    Marr, K.A.2    Queiroz-Telles, F.3
  • 8
    • 4644262187 scopus 로고    scopus 로고
    • Newer systemic antifungal agents: Pharmacokinetics, safety and efficacy
    • Boucher HW, Groll AH, Chiou CC, Walsh TJ. Newer systemic antifungal agents: pharmacokinetics, safety and efficacy. Drugs 64(18), 1997-2020 (2004).
    • (2004) Drugs , vol.64 , Issue.18 , pp. 1997-2020
    • Boucher, H.W.1    Groll, A.H.2    Chiou, C.C.3    Walsh, T.J.4
  • 9
    • 24044445791 scopus 로고    scopus 로고
    • Posaconazole: Clinical pharmacology and potential for management of fungal infections
    • Groll AH, Walsh TJ. Posaconazole: Clinical pharmacology and potential for management of fungal infections. Expert Rev. Anti Infect. Ther. 3(4), 467-487 (2005).
    • (2005) Expert Rev. Anti Infect. Ther , vol.3 , Issue.4 , pp. 467-487
    • Groll, A.H.1    Walsh, T.J.2
  • 10
    • 3242881817 scopus 로고    scopus 로고
    • Posaconazole: A potent, extended-spectrum triazole anti-fungal for the treatment of serious fungal infections
    • Herbrecht R. Posaconazole: a potent, extended-spectrum triazole anti-fungal for the treatment of serious fungal infections. Int. J. Clin. Pract. 58(6), 612-624 (2004).
    • (2004) Int. J. Clin. Pract , vol.58 , Issue.6 , pp. 612-624
    • Herbrecht, R.1
  • 12
    • 23744481877 scopus 로고    scopus 로고
    • Keating GM. Posaconazole. Drugs 65(11), 1553-1567 (2005).
    • (2005) Drugs , vol.65 , Issue.11 , pp. 1553-1567
    • Posaconazole, K.G.M.1
  • 14
    • 0346784897 scopus 로고    scopus 로고
    • Three-dimensional models of wild-type and mutated forms of cytochrome P450 14α-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding
    • Xiao L, Madison V, Chau AS, Loebenberg D, Palermo RE, McNicholas PM. Three-dimensional models of wild-type and mutated forms of cytochrome P450 14α-sterol demethylases from Aspergillus fumigatus and Candida albicans provide insights into posaconazole binding. Antimicrob. Agents Chemother. 48(2), 568-574 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , Issue.2 , pp. 568-574
    • Xiao, L.1    Madison, V.2    Chau, A.S.3    Loebenberg, D.4    Palermo, R.E.5    McNicholas, P.M.6
  • 15
    • 42049114435 scopus 로고    scopus 로고
    • Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048)
    • Nomeir AA, Pramanik BN, Heimark L et al. Posaconazole (Noxafil, SCH 56592), a new azole antifungal drug, was a discovery based on the isolation and mass spectral characterization of a circulating metabolite of an earlier lead (SCH 51048). J. Mass Spectrom. 43(4), 509-517 (2008).
    • (2008) J. Mass Spectrom , vol.43 , Issue.4 , pp. 509-517
    • Nomeir, A.A.1    Pramanik, B.N.2    Heimark, L.3
  • 16
    • 27744582591 scopus 로고    scopus 로고
    • Hydroxylated analogues of the orally active broad spectrum antifungal, SCH 51048 (1), and the discovery of posaconazole [SCH 56592; 2 or (S,S)-5]
    • Bennett F, Saksena AK, Lovey RG et al. Hydroxylated analogues of the orally active broad spectrum antifungal, SCH 51048 (1), and the discovery of posaconazole [SCH 56592; 2 or (S,S)-5]. Bioorg. Med. Chem. Lett. 16(1), 186-190 (2006).
    • (2006) Bioorg. Med. Chem. Lett , vol.16 , Issue.1 , pp. 186-190
    • Bennett, F.1    Saksena, A.K.2    Lovey, R.G.3
  • 17
    • 0032882718 scopus 로고    scopus 로고
    • Antifungal agents: Mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance
    • Ghannoum MA, Rice LB. Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance. Clin. Microbiol. Rev. 12(4), 501-517 (1999).
    • (1999) Clin. Microbiol. Rev , vol.12 , Issue.4 , pp. 501-517
    • Ghannoum, M.A.1    Rice, L.B.2
  • 18
    • 4644332720 scopus 로고    scopus 로고
    • Posaconazole is a potent inhibitor of sterol 14α-demethylation in yeasts and molds
    • Munayyer HK, Mann PA, Chau AS et al. Posaconazole is a potent inhibitor of sterol 14α-demethylation in yeasts and molds. Antimicrob. Agents Chemother. 48(10), 3690-3696 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , Issue.10 , pp. 3690-3696
    • Munayyer, H.K.1    Mann, P.A.2    Chau, A.S.3
  • 19
    • 39149087719 scopus 로고    scopus 로고
    • The evolution of fungal drug resistance: Modulating the trajectory from genotype to phenotype
    • Cowen LE. The evolution of fungal drug resistance: modulating the trajectory from genotype to phenotype. Nat. Rev. Microbiol. 6(3), 187-198 (2008).
    • (2008) Nat. Rev. Microbiol , vol.6 , Issue.3 , pp. 187-198
    • Cowen, L.E.1
  • 22
    • 40549124325 scopus 로고    scopus 로고
    • Subcommittee on Antifungal Susceptibility Testing of the European Committee for Antimicrobial Susceptibility Testing (AFST-EUCAST, EUCAST Definitive Document EDef 7.1: method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts. Clin. Microbiol. Infect. 14(4, 398-405 2002
    • Subcommittee on Antifungal Susceptibility Testing of the European Committee for Antimicrobial Susceptibility Testing (AFST-EUCAST). EUCAST Definitive Document EDef 7.1: method for the determination of broth dilution MICs of antifungal agents for fermentative yeasts. Clin. Microbiol. Infect. 14(4), 398-405 (2002).
  • 23
    • 23744453215 scopus 로고    scopus 로고
    • Espinel-Ingroff A, Barchiesi F, Cuenca-Estrella M et al. International and multicenter comparison of EUCAST and CLSI M27-A2 broth microdilution methods for testing susceptibilities of Candida spp. to fluconazole, itraconazole, posaconazole, and voriconazole. J. Clin. Microbiol. 43(8), 3884-3889 (2005).
    • Espinel-Ingroff A, Barchiesi F, Cuenca-Estrella M et al. International and multicenter comparison of EUCAST and CLSI M27-A2 broth microdilution methods for testing susceptibilities of Candida spp. to fluconazole, itraconazole, posaconazole, and voriconazole. J. Clin. Microbiol. 43(8), 3884-3889 (2005).
  • 24
    • 1542509561 scopus 로고    scopus 로고
    • In vitro activities of voricanazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program
    • Pfaller MA, Messer SA, Boyken L et al. In vitro activities of voricanazole, posaconazole, and fluconazole against 4,169 clinical isolates of Candida spp. and Cryptococcus neoformans collected during 2001 and 2002 in the ARTEMIS global antifungal surveillance program. Diagn. Microbiol. Infect. Dis. 48(3), 201-205 (2004).
    • (2004) Diagn. Microbiol. Infect. Dis , vol.48 , Issue.3 , pp. 201-205
    • Pfaller, M.A.1    Messer, S.A.2    Boyken, L.3
  • 25
    • 33744495089 scopus 로고    scopus 로고
    • Sabatelli F, Patel R, Mann PA et al. In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. Antimicrob. Agents Chemother. 50(6), 2009-2015 (2006).
    • Sabatelli F, Patel R, Mann PA et al. In vitro activities of posaconazole, fluconazole, itraconazole, voriconazole, and amphotericin B against a large collection of clinically important molds and yeasts. Antimicrob. Agents Chemother. 50(6), 2009-2015 (2006).
  • 26
    • 35948961071 scopus 로고    scopus 로고
    • In vitro susceptibility to posaconazole of 1,903 yeast isolates recovered in France from 2003 to 2006 and tested by the method of the European committee on antimicrobial susceptibility testing
    • Lortholary O, Dannaoui E, Raoux D et al. In vitro susceptibility to posaconazole of 1,903 yeast isolates recovered in France from 2003 to 2006 and tested by the method of the European committee on antimicrobial susceptibility testing. Antimicrob. Agents Chemother. 51(9), 3378-3380 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , Issue.9 , pp. 3378-3380
    • Lortholary, O.1    Dannaoui, E.2    Raoux, D.3
  • 27
    • 44449113148 scopus 로고    scopus 로고
    • Posaconazole against Candida glabrata isolates with various susceptibilities to fluconazole
    • Spreghini E, Maida CM, Tomassetti S et al. Posaconazole against Candida glabrata isolates with various susceptibilities to fluconazole. Antimicrob. Agents Chemother. 52(6), 1929-1933 (2008).
    • (2008) Antimicrob. Agents Chemother , vol.52 , Issue.6 , pp. 1929-1933
    • Spreghini, E.1    Maida, C.M.2    Tomassetti, S.3
  • 28
    • 15844411100 scopus 로고    scopus 로고
    • Antifungal activity of posaconazole compared with fluconazole and amphotericin B against yeasts from oropharyngeal candidiasis and other infections
    • Carrillo-Muñoz AJ, Quindos G, Ruesga M et al. Antifungal activity of posaconazole compared with fluconazole and amphotericin B against yeasts from oropharyngeal candidiasis and other infections. J. Antimicrob. Chemother. 55(3), 317-319 (2005).
    • (2005) J. Antimicrob. Chemother , vol.55 , Issue.3 , pp. 317-319
    • Carrillo-Muñoz, A.J.1    Quindos, G.2    Ruesga, M.3
  • 29
    • 45749154585 scopus 로고    scopus 로고
    • MICs and minimum fungicidal concentrations of posaconazole, voriconazole and fluconazole for Cryptococcus neoformans and Cryptococcus gattii
    • Torres-Rodríguez JM, Alvarado-Ramírez E, Murciano F, Sellart M. MICs and minimum fungicidal concentrations of posaconazole, voriconazole and fluconazole for Cryptococcus neoformans and Cryptococcus gattii. J. Antimicrob. Chemother. 62(1), 205-206 (2008).
    • (2008) J. Antimicrob. Chemother , vol.62 , Issue.1 , pp. 205-206
    • Torres-Rodríguez, J.M.1    Alvarado-Ramírez, E.2    Murciano, F.3    Sellart, M.4
  • 32
    • 33847619762 scopus 로고    scopus 로고
    • Torres-Narbona M, Guinea J, Martínez-Alarcón J, Peláez T, Bouza E. In vitro activities of amphotericin B, caspofungin, itraconazole, posaconazole, and voriconazole against 45 clinical isolates of zygomycetes: comparison of CLSI M38-A, Sensititre YeastOne, and the Etest. Antimicrob. Agents Chemother. 51(3), 1126-1129 (2007).
    • Torres-Narbona M, Guinea J, Martínez-Alarcón J, Peláez T, Bouza E. In vitro activities of amphotericin B, caspofungin, itraconazole, posaconazole, and voriconazole against 45 clinical isolates of zygomycetes: comparison of CLSI M38-A, Sensititre YeastOne, and the Etest. Antimicrob. Agents Chemother. 51(3), 1126-1129 (2007).
  • 33
    • 34447265453 scopus 로고    scopus 로고
    • In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents
    • Almyroudis NG, Sutton DA, Fothergill AW, Rinaldi MG, Kusne S. In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents. Antimicrob. Agents Chemother. 51(7), 2587-2590 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , Issue.7 , pp. 2587-2590
    • Almyroudis, N.G.1    Sutton, D.A.2    Fothergill, A.W.3    Rinaldi, M.G.4    Kusne, S.5
  • 34
    • 33749189082 scopus 로고    scopus 로고
    • Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole
    • Wheat LJ, Connolly P, Smedema M et al. Activity of newer triazoles against Histoplasma capsulatum from patients with AIDS who failed fluconazole. J. Antimicrob. Chemother. 57(6), 1235-1239 (2006).
    • (2006) J. Antimicrob. Chemother , vol.57 , Issue.6 , pp. 1235-1239
    • Wheat, L.J.1    Connolly, P.2    Smedema, M.3
  • 35
    • 0037310145 scopus 로고    scopus 로고
    • Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14α-demethylase
    • Mann PA, Parmegiani RM, Wei SQ et al. Mutations in Aspergillus fumigatus resulting in reduced susceptibility to posaconazole appear to be restricted to a single amino acid in the cytochrome P450 14α-demethylase. Antimicrob. Agents Chemother. 47(2), 577-581 (2003).
    • (2003) Antimicrob. Agents Chemother , vol.47 , Issue.2 , pp. 577-581
    • Mann, P.A.1    Parmegiani, R.M.2    Wei, S.Q.3
  • 36
    • 33750581779 scopus 로고    scopus 로고
    • Molecular basis for enhanced activity of posaconazole against Absidia corymbifera and Rhizopus oryzae
    • Chau AS, Chen G, McNicholas PM, Mann PA. Molecular basis for enhanced activity of posaconazole against Absidia corymbifera and Rhizopus oryzae. Antimicrob. Agents Chemother. 50(11), 3917-3919 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , Issue.11 , pp. 3917-3919
    • Chau, A.S.1    Chen, G.2    McNicholas, P.M.3    Mann, P.A.4
  • 37
    • 9144274977 scopus 로고    scopus 로고
    • Changes in susceptibility to posaconazole in clinical isolates of Candida albicans
    • Li X, Brown N, Chau AS et al. Changes in susceptibility to posaconazole in clinical isolates of Candida albicans. J. Antimicrob. Chemother. 53(1), 74-80 (2004).
    • (2004) J. Antimicrob. Chemother , vol.53 , Issue.1 , pp. 74-80
    • Li, X.1    Brown, N.2    Chau, A.S.3
  • 39
    • 38649104145 scopus 로고    scopus 로고
    • Posaconazole activity against Candida glabrata after exposure to caspofungin or amphotericin B
    • Spreghini E, Maida CM, Milici ME, Scalise G, Barchiesi F. Posaconazole activity against Candida glabrata after exposure to caspofungin or amphotericin B. Antimicrob. Agents Chemother. 52(2), 513-517 (2008).
    • (2008) Antimicrob. Agents Chemother , vol.52 , Issue.2 , pp. 513-517
    • Spreghini, E.1    Maida, C.M.2    Milici, M.E.3    Scalise, G.4    Barchiesi, F.5
  • 40
    • 33846585413 scopus 로고    scopus 로고
    • Posaconazole enhances the activity of amphotericin B against Aspergillus hyphae in vitro
    • Perkhofer S, Lugger H, Dierich MP, Lass-Florl C. Posaconazole enhances the activity of amphotericin B against Aspergillus hyphae in vitro. Antimicrob. Agents Chemother. 51(2), 791-793 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , Issue.2 , pp. 791-793
    • Perkhofer, S.1    Lugger, H.2    Dierich, M.P.3    Lass-Florl, C.4
  • 42
    • 40049106188 scopus 로고    scopus 로고
    • In vitro activities of combinations of amphotericin B, posaconazole and four other agents against Rhizopus
    • Ballester F, Pastor FJ, Guarro J. In vitro activities of combinations of amphotericin B, posaconazole and four other agents against Rhizopus. J. Antimicrob. Chemother. 61(3), 755-757 (2008).
    • (2008) J. Antimicrob. Chemother , vol.61 , Issue.3 , pp. 755-757
    • Ballester, F.1    Pastor, F.J.2    Guarro, J.3
  • 43
    • 46249119931 scopus 로고    scopus 로고
    • Posaconazole enhances the activity of amphotericin B against hyphae of zygomycetes in vitro
    • Perkhofer S, Locher M, Cuenca-Estrella M et al. Posaconazole enhances the activity of amphotericin B against hyphae of zygomycetes in vitro. Antimicrob. Agents Chemother. 52(7), 2636-2638 (2008).
    • (2008) Antimicrob. Agents Chemother , vol.52 , Issue.7 , pp. 2636-2638
    • Perkhofer, S.1    Locher, M.2    Cuenca-Estrella, M.3
  • 44
    • 1442349195 scopus 로고    scopus 로고
    • Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: Comparative studies in two laboratories
    • Najvar LK, Cacciapuoti A, Hernandez S et al. Activity of posaconazole combined with amphotericin B against Aspergillus flavus infection in mice: comparative studies in two laboratories. Antimicrob. Agents Chemother. 48(3), 758-764 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , Issue.3 , pp. 758-764
    • Najvar, L.K.1    Cacciapuoti, A.2    Hernandez, S.3
  • 45
    • 12944289675 scopus 로고    scopus 로고
    • Interaction between posaconazole and amphotericin B in concomitant treatment against Candida albicans in vivo
    • Cacciapuoti A, Gurnani M, Halpern J, Norris C, Patel R, Loebenberg D. Interaction between posaconazole and amphotericin B in concomitant treatment against Candida albicans in vivo. Antimicrob. Agents Chemother. 49(2), 638-642 (2005).
    • (2005) Antimicrob. Agents Chemother , vol.49 , Issue.2 , pp. 638-642
    • Cacciapuoti, A.1    Gurnani, M.2    Halpern, J.3    Norris, C.4    Patel, R.5    Loebenberg, D.6
  • 46
    • 33745623992 scopus 로고    scopus 로고
    • Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection
    • Cacciapuoti A, Halpern J, Mendrick C, Norris C, Patel R, Loebenberg D. Interaction between posaconazole and caspofungin in concomitant treatment of mice with systemic Aspergillus infection. Antimicrob, Agents Chemother. 50(7), 2587-2590 (2006).
    • (2006) Antimicrob, Agents Chemother , vol.50 , Issue.7 , pp. 2587-2590
    • Cacciapuoti, A.1    Halpern, J.2    Mendrick, C.3    Norris, C.4    Patel, R.5    Loebenberg, D.6
  • 48
    • 54049146733 scopus 로고    scopus 로고
    • Posaconazole combined with amphotericin B, an effective therapy for a murine disseminated infection caused by Rhizopus oryzae
    • Rodriguez MM, Serena C, Marine M, Pastor FJ, Guarro J. Posaconazole combined with amphotericin B, an effective therapy for a murine disseminated infection caused by Rhizopus oryzae. Antimicrob. Agents Chemother. 52(10), 3786-3788 (2008).
    • (2008) Antimicrob. Agents Chemother , vol.52 , Issue.10 , pp. 3786-3788
    • Rodriguez, M.M.1    Serena, C.2    Marine, M.3    Pastor, F.J.4    Guarro, J.5
  • 49
    • 34248146052 scopus 로고    scopus 로고
    • Therapeutic efficacy of posaconazole against isolates of Candida albicans with different susceptibilities to fluconazole in a vaginal model
    • Gonzalez GM, Robledo E, Saldivar D, Gonzalez G, Bosques F, Garza E. Therapeutic efficacy of posaconazole against isolates of Candida albicans with different susceptibilities to fluconazole in a vaginal model. Med. Mycol. 45(3), 221-224 (2007).
    • (2007) Med. Mycol , vol.45 , Issue.3 , pp. 221-224
    • Gonzalez, G.M.1    Robledo, E.2    Saldivar, D.3    Gonzalez, G.4    Bosques, F.5    Garza, E.6
  • 50
    • 35449003332 scopus 로고    scopus 로고
    • Efficacy of posaconazole and amphotericin B in experimental invasive pulmonary aspergillosis in dexamethasone immunosuppressed rats
    • Ullmann AJ, Krammes E, Sommer S et al. Efficacy of posaconazole and amphotericin B in experimental invasive pulmonary aspergillosis in dexamethasone immunosuppressed rats. J. Antimicrob. Chemother. 60(5), 1080-1084 (2007).
    • (2007) J. Antimicrob. Chemother , vol.60 , Issue.5 , pp. 1080-1084
    • Ullmann, A.J.1    Krammes, E.2    Sommer, S.3
  • 51
    • 4644342873 scopus 로고    scopus 로고
    • Efficacy of posaconazole in a murine model of central nervous system aspergillosis
    • Imai JK, Singh G, Clemons KV, Stevens DA. Efficacy of posaconazole in a murine model of central nervous system aspergillosis. Antimicrob. Agents Chemother. 48(10), 4063-4066 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , Issue.10 , pp. 4063-4066
    • Imai, J.K.1    Singh, G.2    Clemons, K.V.3    Stevens, D.A.4
  • 52
  • 55
    • 0041422239 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults
    • Courtney R, Pai S, Laughlin M, Lim J, Batra V. Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults. Antimicrob. Agents Chemother. 47(9), 2788-2795 (2003).
    • (2003) Antimicrob. Agents Chemother , vol.47 , Issue.9 , pp. 2788-2795
    • Courtney, R.1    Pai, S.2    Laughlin, M.3    Lim, J.4    Batra, V.5
  • 56
    • 1242351713 scopus 로고    scopus 로고
    • Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults
    • Courtney R, Wexler D, Radwanski E, Lim J, Laughlin M. Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults. Br. J. Clin. Pharmacol. 57(2), 218-222 (2004).
    • (2004) Br. J. Clin. Pharmacol , vol.57 , Issue.2 , pp. 218-222
    • Courtney, R.1    Wexler, D.2    Radwanski, E.3    Lim, J.4    Laughlin, M.5
  • 57
    • 13244268757 scopus 로고    scopus 로고
    • Oral bioavailability of posaconazole in fasted healthy subjects - comparison between three regimens and basis for clinical dosage recommendations
    • Ezzet F, Wexler D, Courtney R, Krishna G, Laughlin M et al. Oral bioavailability of posaconazole in fasted healthy subjects - comparison between three regimens and basis for clinical dosage recommendations. Clin. Pharmacokinet. 44(2), 211-220 (2005).
    • (2005) Clin. Pharmacokinet , vol.44 , Issue.2 , pp. 211-220
    • Ezzet, F.1    Wexler, D.2    Courtney, R.3    Krishna, G.4    Laughlin, M.5
  • 58
    • 62949244126 scopus 로고    scopus 로고
    • The pharmacokinetics and absorption of posaconazole oral suspension under various gastric conditions in healthy volunteers
    • DOI:10.1128/AAC.01034-01008
    • Krishna G, Moton A, Ma L, Medlock MM, McLeod J. The pharmacokinetics and absorption of posaconazole oral suspension under various gastric conditions in healthy volunteers. Antimicrob. Agents Chemother. DOI:10.1128/AAC.01034-01008. (2008).
    • (2008) Antimicrob. Agents Chemother
    • Krishna, G.1    Moton, A.2    Ma, L.3    Medlock, M.M.4    McLeod, J.5
  • 59
    • 1442349141 scopus 로고    scopus 로고
    • Pharmacokinetics of posaconazole coadministered with antacid in fasting or nonfasting healthy men
    • Courtney R, Radwanski E, Lim J, Laughlin M. Pharmacokinetics of posaconazole coadministered with antacid in fasting or nonfasting healthy men. Antimicrob. Agents Chemother. 48(3), 804-808 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , Issue.3 , pp. 804-808
    • Courtney, R.1    Radwanski, E.2    Lim, J.3    Laughlin, M.4
  • 60
    • 33646445591 scopus 로고    scopus 로고
    • Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers
    • Sansone-Parsons A, Krishna G, Calzetta A et al. Effect of a nutritional supplement on posaconazole pharmacokinetics following oral administration to healthy volunteers. Antimicrob. Agents Chemother. 50(5), 1881-1883 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , Issue.5 , pp. 1881-1883
    • Sansone-Parsons, A.1    Krishna, G.2    Calzetta, A.3
  • 62
    • 4344700227 scopus 로고    scopus 로고
    • Disposition of posaconazole following single-dose oral administration in healthy subjects
    • Krieter P, Flannery B, Musick T et al. Disposition of posaconazole following single-dose oral administration in healthy subjects. Antimicrob. Agents Chemother. 48(9), 3543-3551 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , Issue.9 , pp. 3543-3551
    • Krieter, P.1    Flannery, B.2    Musick, T.3
  • 63
    • 69449087663 scopus 로고    scopus 로고
    • The pharmacokinetics of posaconazole administered orally versus via a nasogastric tube in healthy subjects
    • Presented at:, Barcelona, Spain, 19-22 April
    • Varkey J, Krishna G, Vickery D et al. The pharmacokinetics of posaconazole administered orally versus via a nasogastric tube in healthy subjects. Presented at: 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Barcelona, Spain, 19-22 April 2008.
    • (2008) 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
    • Varkey, J.1    Krishna, G.2    Vickery, D.3
  • 64
    • 33744498620 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of oral posaconazole in neutropenic stem cell transplant recipients
    • Gubbins PO, Krishna G, Sansone-Parsons A et al. Pharmacokinetics and safety of oral posaconazole in neutropenic stem cell transplant recipients. Antimicrob. Agents Chemother. 50(6), 1993-1999 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , Issue.6 , pp. 1993-1999
    • Gubbins, P.O.1    Krishna, G.2    Sansone-Parsons, A.3
  • 65
    • 33846561513 scopus 로고    scopus 로고
    • Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers
    • Sansone-Parsons A, Krishna G, Simon J et al. Effects of age, gender, and race/ethnicity on the pharmacokinetics of posaconazole in healthy volunteers. Antimicrob. Agents Chemother. 51(2), 495-502 (2007).
    • (2007) Antimicrob. Agents Chemother , vol.51 , Issue.2 , pp. 495-502
    • Sansone-Parsons, A.1    Krishna, G.2    Simon, J.3
  • 66
    • 16844387466 scopus 로고    scopus 로고
    • Posaconazole pharmacokinetics, safety, and tolerability in subjects with varying degrees of chronic renal disease
    • Courtney R, Sansone A, Smith W et al. Posaconazole pharmacokinetics, safety, and tolerability in subjects with varying degrees of chronic renal disease. J. Clin. Pharmacol. 45(2), 185-192 (2005).
    • (2005) J. Clin. Pharmacol , vol.45 , Issue.2 , pp. 185-192
    • Courtney, R.1    Sansone, A.2    Smith, W.3
  • 68
    • 54749151049 scopus 로고    scopus 로고
    • Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome
    • Krishna G, AbuTarif M, Xuan F, Martinho M, Angulo D, Comely OA. Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome. Pharmacotherapy 28(10), 1223-1232 (2008).
    • (2008) Pharmacotherapy , vol.28 , Issue.10 , pp. 1223-1232
    • Krishna, G.1    AbuTarif, M.2    Xuan, F.3    Martinho, M.4    Angulo, D.5    Comely, O.A.6
  • 69
    • 36849064207 scopus 로고    scopus 로고
    • Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease
    • Krishna G, Martinho M, Chandrasekar P, Ullmann AJ, Patino H. Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease. Pharmacotherapy 27(12), 1627-1636 (2007).
    • (2007) Pharmacotherapy , vol.27 , Issue.12 , pp. 1627-1636
    • Krishna, G.1    Martinho, M.2    Chandrasekar, P.3    Ullmann, A.J.4    Patino, H.5
  • 70
    • 33846410666 scopus 로고    scopus 로고
    • Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease
    • Ullmann AJ, Lipton JH, Vesole DH et al. Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. N. Engl. J. Med. 356(4), 335-347 (2007).
    • (2007) N. Engl. J. Med , vol.356 , Issue.4 , pp. 335-347
    • Ullmann, A.J.1    Lipton, J.H.2    Vesole, D.H.3
  • 71
    • 31944443967 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection
    • Ullmann AJ, Cornely OA, Burchardt A et al. Pharmacokinetics, safety, and efficacy of posaconazole in patients with persistent febrile neutropenia or refractory invasive fungal infection. Antimicrob. Agents Chemother. 50(2), 658-666 (2006).
    • (2006) Antimicrob. Agents Chemother , vol.50 , Issue.2 , pp. 658-666
    • Ullmann, A.J.1    Cornely, O.A.2    Burchardt, A.3
  • 73
    • 2042454166 scopus 로고    scopus 로고
    • Determination of fungicidal activities against yeasts and molds: Lessons learned from bactericidal testing and the need for standardization
    • Pfaller MA, Sheehan DJ, Rex JH. Determination of fungicidal activities against yeasts and molds: lessons learned from bactericidal testing and the need for standardization. Clin. Microbiol. Rev. 17(2), 268-280 (2004).
    • (2004) Clin. Microbiol. Rev , vol.17 , Issue.2 , pp. 268-280
    • Pfaller, M.A.1    Sheehan, D.J.2    Rex, J.H.3
  • 74
    • 35448944908 scopus 로고    scopus 로고
    • Correlation of posaconazole minimum fungicidal-concentration and time - kill test against nine Candida species
    • Soczo G, Kardos G, McNicholas PM et al. Correlation of posaconazole minimum fungicidal-concentration and time - kill test against nine Candida species. J. Antimicrob. Chemother. 60(5), 1004-1009 (2007).
    • (2007) J. Antimicrob. Chemother , vol.60 , Issue.5 , pp. 1004-1009
    • Soczo, G.1    Kardos, G.2    McNicholas, P.M.3
  • 75
    • 0033871689 scopus 로고    scopus 로고
    • A comparative study of the in vitro susceptibilities of clinical and laboratory-selected resistant isolates of Aspergillus spp. to amphotericin B, itraconazole, voriconazole and posaconazole (SCH 56592)
    • Manavathu EK, Cutright JL, Loebenberg D, Chandrasekar PH. A comparative study of the in vitro susceptibilities of clinical and laboratory-selected resistant isolates of Aspergillus spp. to amphotericin B, itraconazole, voriconazole and posaconazole (SCH 56592). J. Antimicrob. Chemother. 46(2), 229-234 (2000).
    • (2000) J. Antimicrob. Chemother , vol.46 , Issue.2 , pp. 229-234
    • Manavathu, E.K.1    Cutright, J.L.2    Loebenberg, D.3    Chandrasekar, P.H.4
  • 76
    • 0347361711 scopus 로고    scopus 로고
    • Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis
    • Andes D, Marchillo K, Conklin R et al. Pharmacodynamics of a new triazole, posaconazole, in a murine model of disseminated candidiasis. Antimicrob. Agents Chemother. 48(1), 137-142 (2004).
    • (2004) Antimicrob. Agents Chemother , vol.48 , Issue.1 , pp. 137-142
    • Andes, D.1    Marchillo, K.2    Conklin, R.3
  • 77
    • 0028111473 scopus 로고
    • The postantibiotic effect of antifungat agents against common pathogenic yeasts
    • Turnidge JD, Gudmundsson S, Vogelman B, Craig WA. The postantibiotic effect of antifungat agents against common pathogenic yeasts. J. Antimicrob. Chemother. 34(1), 83-92 (1994).
    • (1994) J. Antimicrob. Chemother , vol.34 , Issue.1 , pp. 83-92
    • Turnidge, J.D.1    Gudmundsson, S.2    Vogelman, B.3    Craig, W.A.4
  • 78
    • 0034102140 scopus 로고    scopus 로고
    • Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans
    • Ernst EJ, Klepser ME, Pfaller MA. Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans. Antimicrob. Agents Chemother. 44(4), 1108-1111 (2000).
    • (2000) Antimicrob. Agents Chemother , vol.44 , Issue.4 , pp. 1108-1111
    • Ernst, E.J.1    Klepser, M.E.2    Pfaller, M.A.3
  • 79
    • 33846462456 scopus 로고    scopus 로고
    • Posaconazole versus fluconazole or itraconazole prophylaxis in patients with neutropenia
    • Cornely OA, Maertens J, Winston DJ et al. Posaconazole versus fluconazole or itraconazole prophylaxis in patients with neutropenia. N. Engl. J. Med. 356(4), 348-359 (2007).
    • (2007) N. Engl. J. Med , vol.356 , Issue.4 , pp. 348-359
    • Cornely, O.A.1    Maertens, J.2    Winston, D.J.3
  • 80
    • 33846439749 scopus 로고    scopus 로고
    • Prophylaxis and aspergillosis - has the principle been proven?
    • De Pauw BE, Donnelly JP. Prophylaxis and aspergillosis - has the principle been proven? N. Engl. J. Med. 356(4), 409-411 (2007).
    • (2007) N. Engl. J. Med , vol.356 , Issue.4 , pp. 409-411
    • De Pauw, B.E.1    Donnelly, J.P.2
  • 81
    • 39449095735 scopus 로고    scopus 로고
    • Treatment of aspergillosis: Clinical practice guidelines of the Infectious Diseases Society of America
    • Walsh TJ, Anaissie EJ, Denning DW et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin. Infect. Dis. 46(3), 327-360 (2008).
    • (2008) Clin. Infect. Dis , vol.46 , Issue.3 , pp. 327-360
    • Walsh, T.J.1    Anaissie, E.J.2    Denning, D.W.3
  • 82
    • 33645782259 scopus 로고    scopus 로고
    • A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS
    • Vazquez JA, Skiest DJ, Nieto L et al. A multicenter randomized trial evaluating posaconazole versus fluconazole for the treatment of oropharyngeal candidiasis in subjects with HIV/AIDS. Clin. Infect. Dis. 42(8), 1179-1186 (2006).
    • (2006) Clin. Infect. Dis , vol.42 , Issue.8 , pp. 1179-1186
    • Vazquez, J.A.1    Skiest, D.J.2    Nieto, L.3
  • 83
    • 33846902613 scopus 로고    scopus 로고
    • Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection
    • Skiest DJ, Vazquez JA, Anstead GM et al. Posaconazole for the treatment of azole-refractory oropharyngeal and esophageal candidiasis in subjects with HIV infection. Clin. Infect. Dis. 44(4), 607-614 (2007).
    • (2007) Clin. Infect. Dis , vol.44 , Issue.4 , pp. 607-614
    • Skiest, D.J.1    Vazquez, J.A.2    Anstead, G.M.3
  • 84
    • 34250731402 scopus 로고    scopus 로고
    • Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection
    • Vazquez JA, Skiest DJ, Tissot-Dupont H, Lennox JL, Boparai N, Isaacs R. Safety and efficacy of posaconazole in the long-term treatment of azole-refractory oropharyngeal and esophageal candidiasis in patients with HIV infection. HIV Clin. Trials 8(2), 86-97 (2007).
    • (2007) HIV Clin. Trials , vol.8 , Issue.2 , pp. 86-97
    • Vazquez, J.A.1    Skiest, D.J.2    Tissot-Dupont, H.3    Lennox, J.L.4    Boparai, N.5    Isaacs, R.6
  • 85
    • 33845710284 scopus 로고    scopus 로고
    • Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: An externally controlled trial
    • Walsh TJ, Raad I, Patterson TF et al. Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial. Clin. Infect. Dis. 44(1), 2-12 (2007).
    • (2007) Clin. Infect. Dis , vol.44 , Issue.1 , pp. 2-12
    • Walsh, T.J.1    Raad, I.2    Patterson, T.F.3
  • 86
    • 56649089881 scopus 로고    scopus 로고
    • Posaconazole as salvage treatment of invasive fungal infections in patients with underlying renal impairment
    • Hachem RY, Langston AA, Graybill JR et al. Posaconazole as salvage treatment of invasive fungal infections in patients with underlying renal impairment. J. Antimicrob. Chemother. 62(6), 1386-1391 (2008).
    • (2008) J. Antimicrob. Chemother , vol.62 , Issue.6 , pp. 1386-1391
    • Hachem, R.Y.1    Langston, A.A.2    Graybill, J.R.3
  • 87
    • 40849093036 scopus 로고    scopus 로고
    • Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: Posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin
    • Raad II, Hanna HA, Boktour M et al. Novel antifungal agents as salvage therapy for invasive aspergillosis in patients with hematologic malignancies: posaconazole compared with high-dose lipid formulations of amphotericin B alone or in combination with caspofungin. Leukemia 22(3), 496-503 (2008).
    • (2008) Leukemia , vol.22 , Issue.3 , pp. 496-503
    • Raad, I.I.1    Hanna, H.A.2    Boktour, M.3
  • 89
  • 90
    • 33646445731 scopus 로고    scopus 로고
    • Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions
    • Raad II, Hachem RY, Herbrecht R et al. Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions. Clin. Infect. Dis. 42(10), 1398-1403 (2006).
    • (2006) Clin. Infect. Dis , vol.42 , Issue.10 , pp. 1398-1403
    • Raad, I.I.1    Hachem, R.Y.2    Herbrecht, R.3
  • 91
    • 33947113790 scopus 로고    scopus 로고
    • Salvage treatment of histoplasmosis with posaconazole
    • Restrepo A, Tobon A, Clark B et al. Salvage treatment of histoplasmosis with posaconazole. J. Infect. 54(4), 319-327 (2007).
    • (2007) J. Infect , vol.54 , Issue.4 , pp. 319-327
    • Restrepo, A.1    Tobon, A.2    Clark, B.3
  • 92
  • 93
    • 34548222507 scopus 로고    scopus 로고
    • Safety, tolerance, and efficacy of posaconazole therapy in patients with nonmeningeal disseminated or chronic pulmonary coccidioidomycosis
    • Catanzaro A, Cloud GA, Stevens DA et al. Safety, tolerance, and efficacy of posaconazole therapy in patients with nonmeningeal disseminated or chronic pulmonary coccidioidomycosis. Clin. Infect. Dis. 45(5), 562-568 (2007).
    • (2007) Clin. Infect. Dis , vol.45 , Issue.5 , pp. 562-568
    • Catanzaro, A.1    Cloud, G.A.2    Stevens, D.A.3
  • 95
    • 10744221934 scopus 로고    scopus 로고
    • Case study: Posaconazole treatment of disseminated phaeohyphomycosis due to Exophiala spinifera
    • Negroni R, Helou SH, Petri N et al. Case study: posaconazole treatment of disseminated phaeohyphomycosis due to Exophiala spinifera. Clin. Infect. Dis. 38(3), e15-e20 (2004).
    • (2004) Clin. Infect. Dis , vol.38 , Issue.3
    • Negroni, R.1    Helou, S.H.2    Petri, N.3
  • 97
    • 13244253740 scopus 로고    scopus 로고
    • Successful therapy of cerebral phaeohyphomycosis due to Ramichloridium mackenziei with the new triazole posaconazole
    • Al-Abdely HM, Alkhunaizi AM, Al-Tawfiq JA, Hassounah M, Rinaldi MG, Sutton DA. Successful therapy of cerebral phaeohyphomycosis due to Ramichloridium mackenziei with the new triazole posaconazole. Med. Mycol. 43(1), 91-95 (2005).
    • (2005) Med. Mycol , vol.43 , Issue.1 , pp. 91-95
    • Al-Abdely, H.M.1    Alkhunaizi, A.M.2    Al-Tawfiq, J.A.3    Hassounah, M.4    Rinaldi, M.G.5    Sutton, D.A.6
  • 98
    • 27144459842 scopus 로고    scopus 로고
    • Activity of posaconazole in the treatment of central nervous system fungal infections
    • Pitisuttithum P, Negroni R, Graybill JR et al. Activity of posaconazole in the treatment of central nervous system fungal infections. J. Antimicrob. Chemother. 56(4), 745-755 (2005).
    • (2005) J. Antimicrob. Chemother , vol.56 , Issue.4 , pp. 745-755
    • Pitisuttithum, P.1    Negroni, R.2    Graybill, J.R.3
  • 99
    • 56049125289 scopus 로고    scopus 로고
    • Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant
    • Alexander BD, Perfect JR, Daly JS et al. Posaconazole as salvage therapy in patients with invasive fungal infections after solid organ transplant. Transplantation 86(6), 791-796 (2008).
    • (2008) Transplantation , vol.86 , Issue.6 , pp. 791-796
    • Alexander, B.D.1    Perfect, J.R.2    Daly, J.S.3
  • 100
    • 33744831964 scopus 로고    scopus 로고
    • Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections
    • Raad II, Graybill JR, Bustamante AB et al. Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections. Clin. Infect. Dis. 42(12), 1726-1734 (2006).
    • (2006) Clin. Infect. Dis , vol.42 , Issue.12 , pp. 1726-1734
    • Raad, I.I.1    Graybill, J.R.2    Bustamante, A.B.3
  • 101
    • 69449108031 scopus 로고    scopus 로고
    • Comparison of posaconazole adverse event profiles in healthy volunteers and in patients with invasive fungal infections
    • Presented at:, Copenhagen, Denmark, 2-5 April
    • Pedicone L, Ullmann A, Graybill J et al. Comparison of posaconazole adverse event profiles in healthy volunteers and in patients with invasive fungal infections. Presented at: 15th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Copenhagen, Denmark, 2-5 April 2005.
    • (2005) 15th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
    • Pedicone, L.1    Ullmann, A.2    Graybill, J.3
  • 102
    • 34347211017 scopus 로고    scopus 로고
    • Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men
    • Krishna G, Sansone-Parsons A, Kantesaria B. Drug interaction assessment following concomitant administration of posaconazole and phenytoin in healthy men. Curr. Med. Res. Opin. 23(6), 1415-1422 (2007).
    • (2007) Curr. Med. Res. Opin , vol.23 , Issue.6 , pp. 1415-1422
    • Krishna, G.1    Sansone-Parsons, A.2    Kantesaria, B.3
  • 103
    • 33947354866 scopus 로고    scopus 로고
    • Evaluation of the pharmacokinetics of posaconazole and rifabutin following co-administration to healthy men
    • Krishna G, Parsons A, Kantesaria B, Mant T. Evaluation of the pharmacokinetics of posaconazole and rifabutin following co-administration to healthy men. Curr. Med. Res. Opin. 23(3), 545-552 (2007).
    • (2007) Curr. Med. Res. Opin , vol.23 , Issue.3 , pp. 545-552
    • Krishna, G.1    Parsons, A.2    Kantesaria, B.3    Mant, T.4
  • 104
    • 1842607473 scopus 로고    scopus 로고
    • Effect of posaconazole on cytochrome P450 enzymes: A randomized, open-label, two-way crossover study
    • Wexler D, Courtney R, Richards W, Banfield C, Lim J, Laughlin M. Effect of posaconazole on cytochrome P450 enzymes: a randomized, open-label, two-way crossover study. Eur. J. Pharm. Sci. 21(5), 645-653 (2004).
    • (2004) Eur. J. Pharm. Sci , vol.21 , Issue.5 , pp. 645-653
    • Wexler, D.1    Courtney, R.2    Richards, W.3    Banfield, C.4    Lim, J.5    Laughlin, M.6
  • 105
    • 69449099570 scopus 로고    scopus 로고
    • posaconazole), oral suspension product information. Schering-Plough
    • NJ, USA 2008
    • Noxafil® (posaconazole), oral suspension product information. Schering-Plough, NJ, USA (2008).
    • Noxafil®1
  • 106
    • 59749090419 scopus 로고    scopus 로고
    • Effect of gastric pH, dosing regimen and prandial state, food and meal timing relative to dose, and gastrointestinal motility on absorption and pharmacokinetics of the antifungal posaconazole
    • Presented at:, Barcelona, Spain, 19-22 April
    • Krishna G, Moton A, Ma L, Malavade D, Medlock M, McLeod J. Effect of gastric pH, dosing regimen and prandial state, food and meal timing relative to dose, and gastrointestinal motility on absorption and pharmacokinetics of the antifungal posaconazole. Presented at: 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Barcelona, Spain, 19-22 April 2008.
    • (2008) 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
    • Krishna, G.1    Moton, A.2    Ma, L.3    Malavade, D.4    Medlock, M.5    McLeod, J.6
  • 109
    • 37549028402 scopus 로고    scopus 로고
    • Antifungal serum concentration monitoring: An update
    • Goodwin ML, Drew RH. Antifungal serum concentration monitoring: an update. J. Antimicrob. Chemother. 61(1), 17-25 (2008).
    • (2008) J. Antimicrob. Chemother , vol.61 , Issue.1 , pp. 17-25
    • Goodwin, M.L.1    Drew, R.H.2
  • 110
    • 42049108830 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of antifungals: Pharmacokinetic and pharmacodynamic considerations
    • Smith J, Andes D. Therapeutic drug monitoring of antifungals: pharmacokinetic and pharmacodynamic considerations. Ther. Drug Monit. 30(2), 167-172 (2008).
    • (2008) Ther. Drug Monit , vol.30 , Issue.2 , pp. 167-172
    • Smith, J.1    Andes, D.2
  • 111
    • 57149096710 scopus 로고    scopus 로고
    • Comparative cost - effectiveness of posaconazole versus fluconazole or itraconazole prophylaxis in patients with prolonged neutropenia
    • Collins CD, Ellis JJ, Kaul DR. Comparative cost - effectiveness of posaconazole versus fluconazole or itraconazole prophylaxis in patients with prolonged neutropenia. Am. J. Health. Syst. Pharm. 65(23), 2237-2243 (2008).
    • (2008) Am. J. Health. Syst. Pharm , vol.65 , Issue.23 , pp. 2237-2243
    • Collins, C.D.1    Ellis, J.J.2    Kaul, D.R.3
  • 112
    • 56649109482 scopus 로고    scopus 로고
    • Economic evaluation of posaconazole vs. standard azole prophylaxis in high risk neutropenic patients in The Netherlands
    • Stam WB, O'Sullivan AK, Rijnders B et al. Economic evaluation of posaconazole vs. standard azole prophylaxis in high risk neutropenic patients in The Netherlands. Eur. J. Haematol. 81(6), 467-474 (2008).
    • (2008) Eur. J. Haematol , vol.81 , Issue.6 , pp. 467-474
    • Stam, W.B.1    O'Sullivan, A.K.2    Rijnders, B.3
  • 113
    • 69449101646 scopus 로고    scopus 로고
    • Posaconazole versus standard azole therapy in the prophylaxis against invasive fungal infeections among high-risk neutropenic patients in Canada: A cost - effectiveness anaylsis
    • Presented at:, Barcelona, Spain, 19-22 April
    • Tahami Monfared AA, O'Sullivan AK, Papadopoulos G. Posaconazole versus standard azole therapy in the prophylaxis against invasive fungal infeections among high-risk neutropenic patients in Canada: a cost - effectiveness anaylsis. Presented at: 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). Barcelona, Spain, 19-22 April 2008.
    • (2008) 18th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID)
    • Tahami Monfared, A.A.1    O'Sullivan, A.K.2    Papadopoulos, G.3
  • 114
    • 69449087114 scopus 로고    scopus 로고
    • Comparative posaconazole versus other antifungals all-cause mortality and cost analyses in patients with refractory invasive aspergillosis
    • Presented at:, Chicago, IL, USA, 17-20 September
    • Herbrecht R, Rajagopalan S, Danna R, Papadopoulos G. Comparative posaconazole versus other antifungals all-cause mortality and cost analyses in patients with refractory invasive aspergillosis. Presented at: 47th Interscience Conference on Antimicrobial Agents and Chemotherapy. Chicago, IL, USA, 17-20 September 2007.
    • (2007) 47th Interscience Conference on Antimicrobial Agents and Chemotherapy
    • Herbrecht, R.1    Rajagopalan, S.2    Danna, R.3    Papadopoulos, G.4


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