ZBP-89 and Sp3 down-regulate while NF-Y up-regulates SOX18 promoter activity in HeLa cells

Molecular Biology Reports

Volumn 36, Issue 5, 2009, Pages 993-1000

  Petrovic, Isidora ^a   Kovacevic Grujicic, Natasa ^a   Stevanovic, Milena ^a  

^a INSTITUTE OF MOLECULAR GENETICS AND GENETIC ENGINEERING   (Serbia)

Author keywords

NF Y; Promoter; SOX18 gene; Sp3; Transcription; ZBP 89

Indexed keywords

CYSTEINE; GUANINE; MITHRAMYCIN; NUCLEAR FACTOR Y; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX18; TRANSCRIPTION FACTOR SP3; TRANSCRIPTION FACTOR ZBP 89; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; GENE; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; SOX 18 GENE; TATA BOX; TRANSCRIPTION REGULATION;

BASE SEQUENCE; CCAAT-BINDING FACTOR; COMPUTATIONAL BIOLOGY; DNA-BINDING PROTEINS; DOWN-REGULATION; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PLICAMYCIN; PROMOTER REGIONS, GENETIC; PROTEIN BINDING; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; SOXF TRANSCRIPTION FACTORS; SP3 TRANSCRIPTION FACTOR; TRANSCRIPTION FACTORS; UP-REGULATION;

EID: 63949085858     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-008-9272-x     Document Type: Article

References (30)

1. LH Pevny R Lovell-Badge 1997 Sox genes find their feet Curr Opin Genet Dev 7 338 344
2. M Wegner 1999 From head to toes: the multiple facets of Sox proteins Nucleic Acids Res 27 1409 1420
3. Y Kamachi M Uchikawa H Kondoh 2000 Pairing SOX off: with partners in the regulation of embryonic development Trends Genet 16 182 187
4. M Downes P Koopman 2001 SOX18 and the transcriptional regulation of blood vessel development Trends Cardiovasc Med 11 318 324
5. C Dong D Wilhelm P Koopman 2004 Sox genes and cancer Cytogenet Genome Res 105 442 447
6. S Stanojcic M Stevanovic 2000 The human SOX18 gene: cDNA cloning and high resolution mapping Biochim Biophys Acta 1492 237 241
7. M Garcia-Ramirez J Martinez-Gonzalez JO Juan-Babot C Rodriguez L Badimon 2005 Transcription factor SOX18 is expressed in human coronary atherosclerotic lesions and regulates DNA synthesis and vascular cell growth Arterioscler Thromb Vasc Biol 25 2398 2403
8. IA Darby T Bisucci S Raghoenath J Olsson GE Muscat P Koopman 2001 Sox18 is transiently expressed during angiogenesis in granulation tissue of skin wounds with an identical expression pattern to Flk-1 mRNA Lab Invest 81 937 943
9. N Young 2006 Effect of disrupted SOX18 transcription factor function on tumor growth, vascularization, and endothelial development J Natl Cancer Inst 98 1060 1067
10. A Irrthum 2003 Mutations in the transcription factor gene SOX18 underlie recessive and dominant forms of hypotrichosis-lymphedema-telangiectasia Am J Hum Genet 72 1470 1478
11. I Petrovic M Stevanovic 2007 The human SOX18 gene: expression analysis and characterization of its 5' flanking region Arch Biol Sci 59 267 272
12. N Kovacevic-Grujicic M Mojsin J Djurovic I Petrovic M Stevanovic 2008 Comparison of promoter regions of SOX3, SOX14 and SOX18 orthologs in mammals DNA Seq 19 185 194
13. S Philipsen G Suske 1999 A tale of three fingers: the family of mammalian Sp/XKLF transcription factors Nucleic Acids Res 27 2991 3000
14. JP Hapgood J Riedemann SD Scherer 2001 Regulation of gene expression by GC-rich DNA cis-elements Cell Biol Int 25 17 31
15. K Quandt K Frech H Karas E Wingender T Werner 1995 MatInd and MatInspector: new fast and versatile tools for detection of consensus matches in nucleotide sequence data Nucleic Acids Res 23 4878 4884
16. N Kovacevic Grujicic M Mojsin A Krstic M Stevanovic 2005 Functional characterization of the human SOX3 promoter: identification of transcription factors implicated in basal promoter activity Gene 344 287 297
17. JD Dignam RM Lebovitz RG Roeder 1983 Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei Nucleic Acids Res 11 1475 1489
18. BM Cons KR Fox 1990 Footprinting studies of sequence recognition by mithramycin Anticancer Drug Des 5 93 97
19. DJ Law SA Tarle JL Merchant 1998 The human ZBP-89 homolog, located at chromosome 3q21, represses gastrin gene expression Mamm Genome 9 165 167
20. JL Merchant 1996 ZBP-89, a Kruppel-like zinc finger protein, inhibits epidermal growth factor induction of the gastrin promoter Mol Cell Biol 16 6644 6653
21. GL Law H Itoh DJ Law GJ Mize JL Merchant DR Morris 1998 Transcription factor ZBP-89 regulates the activity of the ornithine decarboxylase promoter J Biol Chem 273 19955 19964
22. E Wieczorek Z Lin EB Perkins DJ Law JL Merchant ZE Zehner 2000 The zinc finger repressor, ZBP-89, binds to the silencer element of the human vimentin gene and complexes with the transcriptional activator, Sp1 J Biol Chem 275 12879 12888
23. MJ Birnbaum 1995 Sp1 trans-activation of cell cycle regulated promoters is selectively repressed by Sp3 Biochemistry 34 16503 16508
24. S Chu CJ Blaisdell MZ Liu PL Zeitlin 1999 Perinatal regulation of the ClC-2 chloride channel in lung is mediated by Sp1 and Sp3 Am J Physiol 276 L614 624
25. HS Kwon MS Kim HJ Edenberg MW Hur 1999 Sp3 and Sp4 can repress transcription by competing with Sp1 for the core cis-elements on the human ADH5/FDH minimal promoter J Biol Chem 274 20 28
26. MS Wiebe PJ Wilder D Kelly A Rizzino 2000 Isolation, characterization, and differential expression of the murine Sox-2 promoter Gene 246 383 393
27. DC Colter S Piera-Velazquez DF Hawkins MK Whitecavage SA Jimenez DG Stokes 2005 Regulation of the human Sox9 promoter by the CCAAT-binding factor Matrix Biol 24 185 197
28. J Djurovic M Stevanovic 2004 Structural and functional characterization of the human SOX14 promoter Biochim Biophys Acta 1680 53 59
29. A Krstic M Mojsin M Stevanovic 2007 Regulation of SOX3 gene expression is driven by multiple NF-Y binding elements Arch Biochem Biophys 467 163 173
30. X Li JW Xiong CS Shelley H Park MA Arnaout 2006 The transcription factor ZBP-89 controls generation of the hematopoietic lineage in zebrafish and mouse embryonic stem cells Development 133 3641 3650