Perinatal regulation of the ClC-2 chloride channel in lung is mediated by Sp1 and Sp3

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 276, Issue 4 20-4, 1999, Pages

  Chu, Shijian ^a,b   Blaisdell, Carol J ^a   Liu, Min Zhi M ^a   Zeitlin, Pamela L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Development; Epithelial cell; Gene expression; Ribonucleic acid polymerase II; Transcription

Indexed keywords

CHLORIDE CHANNEL; CHLORIDE ION; CYTOSINE; GUANINE; LUCIFERASE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL IMMORTALIZATION; CONTROLLED STUDY; ELECTROPHORETIC MOBILITY; FETUS; FETUS DEVELOPMENT; GENETIC TRANSCRIPTION; LUNG ALVEOLUS CELL TYPE 2; LUNG ALVEOLUS EPITHELIUM; LUNG DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRIORITY JOURNAL; PROMOTER REGION; RAT; TATA BOX;

EID: 0032924826     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.1999.276.4.l614     Document Type: Article

References (35)

1. Apt, D., R. M. Watts, G. Suske, and H.-U. Bernard. High Sp1/Sp3 ratios in epithelial cells during epithelial differentiation and cellular transformation correlate with the activation of the HPV-16 promoter. Virology 224: 281-291, 1997.
2. Armstrong, S. A., D. A. Barry, R. W. Leggett, and C. R. Mueller. Casein kinase II-mediated phosphorylation of the C terminus of Sp1 decreases its DNA binding activity. J. Biol. Chem. 272: 13489-13495, 1997.
3. Azizkhan, J. C., D. E. Jensen, A. J. Pierce, and M. Wade. Transcription from TATA-less promoters: dihydrofolate reductase as a model. Crit. Rev. Eukaryot. Gene Expr. 3: 229-254, 1993.
4. Chou, J.-L., R. Rozmahel, and L.-C. Tsui. Characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene. J. Biol. Chem. 266: 24471-24476, 1991.
5. Chu, S., and P. L. Zeitlin. Alternative mRNA splice variants of the rat ClC-2 chloride channel gene are expressed in lung: genomic sequence and organization of ClC-2. Nucleic Acids Res. 25: 4153-4159, 1997.
6. Cid, L. P., C. Montrose-Rafizadeh, D. I. Smith, W. B. Guggino, and G. R. Cutting. Cloning of a putative human voltage-gated chloride channel (ClC-2) cDNA widely expressed in human tissues. Hum. Mol. Genet. 4: 407-413, 1995.
7. Cooke, J., M. A. Nowak, M. Boerlijst, and J. Maynard-Smith. Evolutionary origins and maintenance of redundant gene expression during matazoan development. Trends Genet. 13: 360-364, 1997.
8. D'Angelo, D. D., B. G. Oliver, M. G. Davis, T. S. McCluskey, and G. W. Dorn. Novel role for Sp1 in phorbol ester enhancement of human platelet thromboxane receptor gene expression. J. Biol. Chem. 271: 19696-19704, 1996.
9. Dennig, J., G. Hagen, M. Beato, and G. Suske. Members of the Sp transcription factor family control transcription from the uteroglobin promoter. J. Biol. Chem. 270: 12737-12744, 1995.
10. Dynan, W. S., and R. Tjian. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell 35: 79-87, 1983.
11. Hagen, G., S. Muller, M. Beato, and G. Suske. Cloning by recognition site screening of two novel GT box binding proteins: a family of Sp1 related genes. Nucleic Acids Res. 20: 5519-5525, 1992.
12. Jackson, S. P., J. J. MacDonald, S. Lees-Miller, and R. Tjian. GC box binding induces phosphorylation of Sp1 by a DNA-dependent protein kinase. Cell 63: 155-165, 1990.
13. Kawasaki, M., S. Uchida, T. Monkawa, A. Miyawaki, K. Mikoshiba, F. Marumo, and S. Sasaki. Cloning and expression of a protein kinase C-regulated chloride channel abundantly expressed in rat brain neuronal cells. Neuron 12: 597-604, 1994.
14. Kingsley, C., and A. Winoto. Cloning of GT box-binding proteins: a novel Sp1 multigene family regulating T-cell receptor gene expression. Mol. Cell. Biol. 12: 4251-4261, 1992.
15. Koh, J., T. J. Sferra, and F. S. Collins. Characterization of the cystic fibrosis transmembrane conductance regulator promoter region. J. Biol. Chem. 268: 15912-15921, 1993.
16. Kramer, A., and W. Keller. Preparation and fractionation of mammalian extracts active in pre-mRNA splicing. Methods Enzymol. 181: 3-19, 1990.
17. Krochmal, E. M., S. T. Ballard, J. R. Yankaskas, R. C. Boucher, and J. T. Gatzy. Volume and ion transport by fetal rat alveolar and tracheal epithelia in submersion culture. Am. J. Physiol. 256 (Renal Fluid Electrolyte Physiol. 25): F397-F407, 1989.
18. Mallampalli, R. K., C. S. Floerchinger, and G. W. Hunninghake. Isolation and immortalization of rat pre-type II cell lines. In Vitro Cell. Dev. Biol. 28A: 181-187, 1992.
19. Margana, R. K., and V. Boggaram. Functional analysis of surfactant protein B (SP-B) promoter. Sp1, Sp3, TTF-1, and HNF-3α transcription factors are necessary for lung cell-specific activation of SP-B gene transcription. J. Biol. Chem. 272: 3083-3090, 1997.
20. Marin, M., A. Karis, P. Visser, F. Grosveld, and S. Philipsen. Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation. Cell 89: 619-628, 1997.
21. McGrath, S. A., A. Basu, and P. L. Zeitlin. Cystic fibrosis gene and protein expression during fetal lung development. Am. J. Respir. Cell Mol. Biol. 8: 201-208, 1993.
22. Murray, C. B., S. Chu, and P. L. Zeitlin. Gestational and tissue-specific regulation of ClC-2 chloride channel expression. Am. J. Physiol. 271 (Lung Cell. Mol. Physiol. 15): L829-L837, 1996.
23. Murray, C. B., M. M. Morales, T. R. Flotte, S. A. McGrath-Morrow, W. B. Guggino, and P. L. Zeitlin. ClC-2: a developmentally dependent chloride channel expressed in the fetal lung and downregulated after birth. Am. J. Respir. Cell Mol. Biol. 12: 597-604, 1995.
24. O'Brodovich, H. M., B. Rafii, and M. Post. Bioelectric properties of fetal alveolar epithelial monolayers. Am. J. Physiol. 258 (Lung Cell. Mol. Physiol. 2): L201-L206, 1990.
25. Quinn, J. P., J. McAllister, and S. Mendelson. Multiple protein complexes, including AP2 and Sp1, interact with a specific site within the rat preprotachykinin-A promoter. Biochim. Biophys. Acta 1263: 25-34, 1995.
26. Riordan, J. R., J. M. Rommens, B.-S. Kerem, N. Alon, R. Rozmahel, Z. Grzelczak, J. Zielenski, S. Lok, N. Plavsic, J.-L. Chou, M. L. Drumm, M. C. Iannuzzi, F. S. Collins, and L.-C. Tsui. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 245: 1066-1073, 1989.
27. Saffer, J. D., S. P. Jackson, and M. B. Annarella. Developmental expression of Sp1 in the mouse. Mol. Cell. Biol. 11: 2189-2199, 1991.
28. Schwiebert, E. M., L. P. Cid-Soto, D. Stafford, M. Carter, C. J. Blaisdell, P. L. Zeitlin, W. B. Guggino, and G. R. Cutting. Analysis of ClC-2 channels as an alternative pathway for chloride conduction in cystic fibrosis airway cells. Proc. Natl. Acad. Sci. USA 95: 3879-3884, 1998.
29. Shpakovski, G. V., J. Acker, M. Wintzerith, J.-F. Lacroix, P. Thuriaux, and M. Vigneron. Four subunits that are shared by the three classes of RNA polymerase are functionally interchangeable between Homo sapiens and Saccharomyces cerevisiae. Mol. Cell. Biol. 15: 4702-4710, 1995.
30. Steinmeyer, K., C. Ortland, and T. J. Jentsch. Primary structure and functional expression of a developmentally regulated skeletal muscle chloride channel. Nature 354: 301-304, 1991.
31. Strang, L. B. Fetal lung liquid: secretion and reabsorption. Physiol. Rev. 71: 991-1016, 1991.
32. Thiemann, A., S. Grunder, M. Pusch, and T. J. Jentsch. A chloride channel widely expressed in epithelial and non-epithelial cells. Nature 356: 57-60, 1992.
33. Toonen, R. F. G., S. Gowan, and C. D. Bingle. The lung enriched transcription factor TTF-1 and the ubiquitously expressed proteins Sp1 and Sp3 interact with elements located in the minimal promoter of the rat Clara cell secretory protein gene. Biochem. J. 316: 467-473, 1996.
34. Zeitlin, P. L., G. M. Loughlin, and W. B. Guggino. Ion transport in cultured fetal and adult rabbit tracheal epithelia. Am. J. Physiol. 254 (Cell Physiol. 23): C691-C698, 1988.
35. Zhang, S., and K.-H. Kim. Protein kinase CK2 down-regulates glucose-activated expression of the acetyl-CoA carboxylase gene. Arch. Biochem. Biophys. 338: 227-232, 1997.