5-FU pretreatment potentiates cisplatin-induced apoptosis through up-regulation of thrombospondin-1 in head and neck squamous cell carcinomas

Cancer Chemotherapy and Pharmacology

Volumn 63, Issue 6, 2009, Pages 1181-1183

  Xu, Bei ^a   Liu, Peng ^a  

^a NANJING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CISPLATIN; FLUOROURACIL; MESSENGER RNA; SHORT HAIRPIN RNA; THROMBOSPONDIN 1;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; CANCER CELL CULTURE; CANCER COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; EXTRACELLULAR MATRIX; GENE SILENCING; HEAD AND NECK CARCINOMA; HUMAN; HUMAN CELL; LETTER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SQUAMOUS CELL CARCINOMA; TRANSCRIPTION REGULATION; UPREGULATION;

APOPTOSIS; CELL LINE, TUMOR; CISPLATIN; DRUG SYNERGISM; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLUOROURACIL; HEAD AND NECK NEOPLASMS; HUMANS; THROMBOSPONDIN 1; TRANSFECTION; UP-REGULATION;

EID: 63949083023     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-008-0880-x     Document Type: Letter

References (12)

1. K Ijichi M Adachi Y Hasegawa T Ogawa H Nakamura A Kudoh 2008 Pretreatment with 5-FU enhances cisplatin cytotoxicity in head and neck squamous cell carcinoma cells Cancer Chemother Pharmacol 62 5 745 752
2. A Saumet MB Slimane M Lanotte J Lawler V Dubernard 2005 Type 3 repeat/C-terminal domain of thrombospondin-1 triggers caspase-independent cell death through CD47/alphavbeta3 in promyelocytic leukemia NB4 cells Blood 106 2 658 667
3. P Liu Y Wang YH Li C Yang YL Zhou B Li 2003 Adenovirus-mediated gene therapy with an antiangiogenic fragment of thrombospondin-1 inhibits human leukemia xenograft growth in nude mice Leuk Res 27 8 701 708
4. H Chen ME Herndon J Lawler 2000 The cell biology of thrombospondin-1 Matrix Biol 19 7 597 614
5. CB Carlson J Lawler DF Mosher 2008 Structures of thrombospondins Cell Mol Life Sci 65 5 672 686
6. K Li M Yang PM Yuen KW Chik CK Li MM Shing 2003 Thrombospondin-1 induces apoptosis in primary leukemia and cell lines mediated by CD36 and Caspase-3 Int J Mol Med 12 6 995 1001
7. G Roue N Bitton VJ Yuste T Montange M Rubio F Dessauge 2003 Mitochondrial dysfunction in CD47-mediated caspase-independent cell death: ROS production in the absence of cytochrome c and AIF release Biochimie 85 8 741 746
8. V Mateo EJ Brown G Biron M Rubio A Fischer FL Deist 2002 Mechanisms of CD47-induced caspase-independent cell death in normal and leukemic cells: link between phosphatidylserine exposure and cytoskeleton organization Blood 100 8 2882 2890
9. PP Manna WA Frazier 2004 CD47 mediates killing of breast tumor cells via Gi-dependent inhibition of protein kinase A Cancer Res 64 3 1026 1036
10. A Weber UR Hengge I Stricker I Tischoff A Markwart K Anhalt 2007 Protein microarrays for the detection of biomarkers in head and neck squamous cell carcinomas Hum Pathol 38 2 228 238
11. HY Zhao A Ooyama M Yamamoto R Ikeda M Haraguchi S Tabata 2008 Down regulation of c-Myc and induction of an angiogenesis inhibitor, thrombospondin-1, by 5-FU in human colon cancer KM12C cells Cancer Lett 270 1 156 163
12. HY Zhao A Ooyama M Yamamoto R Ikeda M Haraguchi S Tabata 2008 Molecular basis for the induction of an angiogenesis inhibitor, thrombospondin-1, by 5-fluorouracil Cancer Res 68 17 7035 7041