Synthesis of novel halogenated 4(1H)-quinolones by thermolysis of arylaminomethylene-1,3-dioxane-4,6-diones

Synthesis

Volumn , Issue 1, 2009, Pages 69-78

  Rotzoll, Sven ^a   Reinke, Helmut ^a   Fischer, Christine ^a   Langer, Peter ^a  

^a UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Cyclizations; N heterocycles; Quinolones

Indexed keywords

CYCLIZATIONS; MELDRUM'S ACIDS; N-HETEROCYCLES; QUINOLONE; QUINOLONES;

ETHERS; THERMOLYSIS;

CYCLIZATION;

2,2 DIMETHYL 5 [(((2 (TRIFLUOROMETHYL)PHENYL)AMINO)METHYLENE] 1,3 DIOXANE 4,6 DIONE; 2,2 DIMETHYL 5 [((2,4,5-TRICHLOROPHENYL)AMINO)METHYLENE] 1,3 DIOXANE 4,6 DIONE; 2,2 DIMETHYL 5 [(NAPHTHALEN 1 YLAMINO)METHYLENE] 1,3 DIOXANE 4,6 DIONE; 2,2 DIMETHYL 5 [[(2,4,5 TRIMETHYLPHENYL)AMINO]METHYLENE] 1,3 DIOXANE 4,6 DIONE; 5 [((2 BROMOPHENYL)AMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [((2,3 DICHLOROPHENYL)AMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [((2,4 DIBROMOPHENYL)AMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [((2,4 DICHLOROPHENYL)AMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [((2,5 DICHLOROPHENYL)AMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [((3 BROMOPHENYL)AMINO)METHYLENE] 1,3 DIOXANE 4,6 DIONE; 5 [((4 CHLORO 2 METHYLPHENYL)AMINO)METHYLENE]2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [((4 IODOPHENYL)AMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [(BIPHENYL 2 YLAMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(2,5 DIMETHYLPHENYL)AMINO]METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(3,5 DIMETHYLPHENYL)AMINO]METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5 [[(4-TERT-BUTYLPHENYL)AMINO]METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 5,6,8 TRIMETHYLQUINOLIN 4(1H) ONE; 5,7 DIMETHYLQUINOLIN 4(1H) ONE; 5,8 DIMETHYLQUINOLIN 4(1H) ONE; 5-[((2 CHLORO 4 METHYLPHENYL)AMINO)METHYLENE] 2,2 DIMETHYL 1,3 DIOXANE 4,6 DIONE; 6 CHLORO 8 METHYLQUINOLIN 4(1H) ONE; 6 TERT BUTYLQUINOLIN 4(1H) ONE; 7 BROMOQUINOLIN 4(1H) ONE; 8 CHLORO 6 METHYLQUINOLIN 4(1H) ONE; 8 PHENYLQUINOLIN 4(1H) ONE; BENZO[H]QUINOLIN 4(1H) ONE; CIPROFLOXACIN; NORFLOXACIN; NORFLUXX; QUINOLINE DERIVED ANTIINFECTIVE AGENT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ARTICLE; CYCLIZATION; DRUG STRUCTURE; DRUG SYNTHESIS; HALOGENATION;

EID: 63849329381     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0028-1083237     Document Type: Article

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