EPC adhesion to arteries from diabetic and non-diabetic patients: Effect of pioglitazone

Frontiers in Bioscience

Volumn 14, Issue 9, 2009, Pages 3608-3618

  Ruiz, Emilio ^a   Redondo, Santiago ^a   Gordillo Moscoso, Antonio ^a   Rodriguez, Enrique ^b   Reguillo, Fernando ^b   Martinez Gonzalez, Jose ^c   Tejerina, Teresa ^a  

^a SCHOOL OF MEDICINE   (Spain)

^b HOSPITAL CLÍNICO SAN CARLOS   (Spain)

^c HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

Author keywords

Cyclooxygenase 2; Diabetes mellitus; Endothelial progenitor cells; SDF 1

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTIDIABETIC AGENT; PIOGLITAZONE;

ARTICLE; CASE CONTROL STUDY; CELL ADHESION; CELL CULTURE; CYTOLOGY; DIABETES MELLITUS; DRUG EFFECT; FLOW CYTOMETRY; HUMAN; IMMUNOHISTOCHEMISTRY; PATHOLOGY; STEM CELL; VASCULAR ENDOTHELIUM;

CASE-CONTROL STUDIES; CELL ADHESION; CELLS, CULTURED; DIABETES MELLITUS; ENDOTHELIUM, VASCULAR; FLOW CYTOMETRY; HUMANS; HYPOGLYCEMIC AGENTS; IMMUNOHISTOCHEMISTRY; STEM CELLS; THIAZOLIDINEDIONES;

EID: 63849295679     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2735/3475     Document Type: Article

References (40)

1. American Diabetes Association. Standards of medical care in diabetes-2008. Diabetes Care 31 Suppl 1, S12-S54 (2008)
2. S. Redondo, E. Ruiz, C. G. Santos-Gallego, E. Padilla and T. Tejerina. Pioglitazone induces vascular smooth muscle cell apoptosis through a peroxisome proliferatormechanism. Diabetes 54, 811-817(2005)
3. E. B. Okon, A. W. Chung, P. Rauniyar, E. Padilla, T. Tejerina, B. M. McManus, H. Luo and C. van Breemen. Compromised arterial function in human type 2 diabetic patients. Diabetes 54, 2415-2423(2005) (Pubitemid 41134270)
4. G. P. Fadini, M. Miorin, M. Facco, S. Bonamico, I. Baesso, F. Grego, M. Menegolo, S. V. de Kreutzenberg, A. Tiengo, C. Agostini and C. Avogaro. Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus. J Am Coll Cardiol 1449-1457 (2005) (Pubitemid 40615617)
5. G. P. Fadini, S. Sartore, M. Schiavon, M. Albiero, I. Baesso, A. Cabrelle, C. Agostini and A. Avogaro. Diabetes impairs progenitor cell mobilisation after hindlimb ischaemia reperfusion injury in rats. Diabetologia 49, 3075-3084(2006) (Pubitemid 44730312)
6. M. Hristov, A. Zernecke, E. A. Liehn and C. Weber. Regulation of endothelial progenitor cell homing after arterial injury. Thromb Haemost 98, 274-277(2007) (Pubitemid 47250227)
7. D. A. Ingram, N. M. Caplice and M. C. Yoder MC. Unresolved questions, changing definitions, and novel paradigms for defining endothelial progenitor cells. Blood 106, 1525-1531(2005) (Pubitemid 41208561)
8. D. Y. Yoon, J. Hur, K. W. Park, J. H. Kim, C. S. Lee, I. Y. Oh, T. Y. Kim, H. J. Cho, H. J. Kang, I. H. Chae, H. K. Yang, B. H. Oh, Y. B. Park and H. S. Kim. Synergistic neovascularization by mixed transplantation of early endothelial progenitor cells and late outgrowth endothelial cells: the role of angiogenic cytokines and matrix metalloproteinases. Circulation 112, 1618-1627(2005) (Pubitemid 41324524)
9. G. P. Meyer, K. C. Wollert, J. Lotz, J. Steffens, P. Lippolt, S. Fichtner, H. Hecker, A. Schaefer, L. Arseniev, B. Hertenstein, A. Ganser and H. Drexler. Intracoronary bone marrow cell transfer after myocardial infarction: eighteen months' follow-up data from the randomized, controlled BOOST (BOne marrOw transfer to enhance ST-elevation infarct regeneration) trial. Circulation 113, 1287-1294(2006) (Pubitemid 43739450)
10. M. Hristov, N. Heussen, A. Schober and C. Weber. Intracoronary infusion of autologous bone marrow cells and left ventricular function after acute myocardial infarction: a meta-analysis. J Cell Mol Med 10, 727-33(2006) (Pubitemid 44874281)
11. R. Wilcox, S. Kupfer, E. Erdmann, PROactive Study investigators. Effects of pioglitazone on major adverse cardiovascular events in high-risk patients with type 2 diabetes: results from PROspective pioglitAzone Clinical Trial In macro Vascular Events (PROactive 10). Am Heart J 155, 712-17(2008)
12. G. Orasanu, O. Ziouzenkova, P. R. Devchand, V. Nehra, O. Hamdy, E. S. Horton and J. Plutzky. The peroxisome proliferator-activated receptor-gamma agonist pioglitazone represses inflammation in a peroxisome proliferator- activated receptor-alphadependent manner in vitro and in vivo in mice. J Am Coll Cardiol 52, 869-881(2008)
13. M. Davidson, P. M. Meyer, S. Haffner, S. Feinstein, R. Sr. D'Agostino, G. T. Kondos, A. Perez, Z. Chen and T. Mazzone. Increased high-density lipoprotein cholesterol predicts the pioglitazone-mediated reduction of carotid intima-media thickness progression in patients with type 2 diabetes mellitus. Circulation 117, 2123-2130(2008) (Pubitemid 351572171)
14. C. Gensch, Y. P. Clever, C. Werner, M. Hanhoun, M. Böhm and U. Laufs. The PPAR-gamma agonist pioglitazone increases neoangiogenesis and prevents apoptosis of endothelial progenitor cells. Atherosclerosis 192, 67-74(2007) (Pubitemid 46628806)
15. D. H. Walter, J. Haendeler, J. Reinhold, U. Rochwalsky, F. Seeger, J. Honold, J. Hoffmann, C. Urbich, R. Lehmann, F. Arenzana-Seisdesdos, A. Aicher, C. Heeschen, S. Fichtlscherer, A. M. Zeiher and S. Dimmeler. Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease. Circ Res 97, 1142-1151(2005)
16. D. J. Ceradini, A. R. Kulkarni, M. J. Callaghan, O. M. Tepper, N. Bastidas, M. E. Kleinman, J. M. Capla, R. D. Galiano, J. P. Levine and G. C. Gurtner. Progenitor cell trafficking is regulated by hypoxic gradients through HIF-1 induction of SDF-1. Nat Med 10, 858-864(2004) (Pubitemid 39070860)
17. S. Redondo, M. Hristov, D. Gümbel, T. Tejerina and C. Weber. Biphasic effect of pioglitazone on isolated human endothelial progenitor cells: involvement of peroxisome proliferator-activated receptor-gamma and transforming growth factor-beta1. Thromb Haemost 97, 979-987(2007) (Pubitemid 46939212)
18. E. W. Koo and A. I. Gotlieb. Endothelial stimulation of intimal cell proliferation in a porcine aortic organ culture. Am J Pathol 134, 497-503(1989) (Pubitemid 19082844)
19. J. M. Ramirez, A. Triviño, A. I. Ramirez, J. J. Salazar and J. Garcia-Sanchez. Immunohistochemical study of human retinal astroglia. Vis Res 34, 1935-1946(1994)
20. C. Werner, C. H. Kamani, C. Gensch, M. Bohm and U. Laufs. The peroxisome proliferator-activated receptorgamma agonist pioglitazone increases number and function of endothelial progenitor cells in patients with coronary artery disease and normal glucose tolerance. Diabetes 56, 2609-2615(2007) (Pubitemid 47523269)
21. L. Bindslev, M. Haack-Sorensen, K. Bisgaard, L. Kragh, S. Mortensen, B. Hesse, A. Kjaer and J. Kastrup. Labelling of human mesenchymal stem cells with indium-111 for SPECT imaging: effect on cell proliferation and differentiation. Eur J Nucl Med Mol Imaging 33, 1171-1177(2006) (Pubitemid 44484473)
22. V. Toschi, R. Gallo, M. Lettino, J. T. Fallon, S. D. Gertz, A. Fernandez-Ortiz, J. H. Chesebro, L. Badimon, Y. Nemerson, V. Fuster and J. J. Badimon. Tissue factor modulates the thrombogenicity of human atherosclerotic plaques. Circulation 95, 594-599(1997) (Pubitemid 27063034)
23. L. Badimon, J. Martinez-Gonzalez, T. Royo, R. Lassila and J. J. Badimon. A sudden increase in plasma epinephrine levels transiently enhances platelet deposition on severely damaged arterial wall-studies in a porcine model. Thromb Haemost 82, 1736-1742(1999)
24. Y. Aizawa, J. Kawabe, N. Hasebe, N. Takehara and K. Kikuchi. Pioglitazone enhances cytokine-induced apoptosis in vascular smooth muscle cells and reduces intimal hyperplasia. Circulation 104, 455-460(2001) (Pubitemid 32678277)
25. S. Qin, T. Liu, V. S. Kamanna, M. L. Kashyap. Pioglitazone stimulates apolipoprotein A-I production without affecting HDL removal in HepG2 cells: involvement of PPAR-alpha. Arterioscler Thromb Vasc Biol 27, 2428-2434(2007) (Pubitemid 350203960)
26. T. Thum, D. Fraccarollo, M. Schultheiss, S. Froese, P. Galuppo, J. D. Widder, D. Tsikas, G. Ertl and J. Bauersachs. Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. Diabetes 56, 666-674(2007) (Pubitemid 46348461)
27. O. M. Tepper, R. D. Galiano, J. M. Capla, C. Kalka, P. J. Gagne, G. R. Jacobowitz, J. P. Levine and G. C. Gurtner. Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 106, 2781-86(2002) (Pubitemid 35396976)
28. O. Dormond, A. Foletti, C. Paroz and C. Ruegg. NSAIDs inhibit alpha V beta 3 integrin mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. Nat Med 7, 1041-1047(2001) (Pubitemid 32937385)
29. Y. S. Kim, L. U. Bigliani, M. Fujisawa, K. Murakami, S. S. Chang, H. J. Lee, F. Y. Lee and T. A. Blaine. Stromal cell-derived factor 1 (SDF-1, CXCL12) is increased in subacromial bursitis and downregulated by steroid and nonsteroidal anti-inflammatory agents. J Orthop Res 24, 1756-1764(2006) (Pubitemid 44203307)
30. J. Yamaguchi, K. F. Kusano, O. Masuo, A. Kawamoto, M. Silver, S. Murasawa, M. Bosch-Marce, H. Masuda, D. W. Losordo, J. M. Isner and T. Asahara. Stromal cellderived factor-1 effects on ex vivo expanded endothelial progenitor cell recruitment for ischemic neovascularization. Circulation 107, 1322-1328(2003) (Pubitemid 36314418)
31. A. D. Bhatwadekar, J. V. Glenn, G. Li, T. M. Curtis, T. A. Gardiner and A. W. Stitt. Advanced glycation of fibronectin impairs vascular repair by endothelial progenitor cells: implications for vasodegeneration in diabetic retinopathy. Invest Ophthalmol Vis Sci 49, 1232-41(2008)
32. E. Chavakis, A. Hain, M. Vinci, G. Carmona, M. E. Bianchi, P. Vajkoczy, A. M. Zeiher, T. Chavakis and S. Dimmeler. High-mobility group box 1 activates integrindependent homing of endothelial progenitor cells. Circ Res 100, 204-212(2007) (Pubitemid 46208720)
33. M. L. Balestrieri, M. Rienzo, F. Felice, R. Rossiello, V. Grimaldi, L. Milone, A. Casamassimi, L. Servillo, B. Farzati, A. Giovane and C. Napoli. High glucose downregulates endothelial progenitor cell number via SIRT1. Biochim Biophys Acta 1784, 936-945(2008)
34. S. Kuki, T. Imanishi, K. Kobayashi, Y. Matsuo, M. Obana and T. Akasaka. Hyperglycemia accelerated endothelial progenitor cell senescence via the activation of p38 mitogen-activated protein kinase. Circ J 70, 1076-1081(2006) (Pubitemid 44161749)
35. S. Gadau, C. Emanueli, S. Van Linthout, G. Graiani, M. Todaro, M. Meloni, I. Campesi, G. Invernici, F. Spillmann, K. Ward and P. Madeddu. Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis. Diabetologia 49, 405-420(2006) (Pubitemid 43185412)
36. V. Marchetti, R. Menghini, S. Rizza, A. Vivanti, T. Feccia, D. Lauro, A. Fukamizu, R. Lauro, M. Federici. Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling. Diabetes 55, 2231-2237(2006) (Pubitemid 44743619)
37. Y. H. Chen, S. J. Lin, F. Y. Lin, T. C. Wu, C. R. Tsao, P. H. Huang, P. L. Liu, Y. L. Chen and J. W. Chen. High glucose impairs early and late endothelial progenitor cells by modifying nitric oxide-related but not oxidative stressmediated mechanisms. Diabetes 56, 1559-1568(2007)
38. C. Urbich, E. Dernbach, L. Rössig, A. M. Zeiher and S. Dimmeler. High glucose reduces cathepsin L activity and impairs invasion of circulating progenitor cells. J Mol Cell Cardiol 45, 429-436(2008)
39. L. M. Leesnitzer, D. J. Parks, R. K. Bledsoe, J. E. Cobb, J. L. Collins, T. G. Consler, R. G. Davis, E. A. Hull-Ryde, J. M. Lenhard, L. Patel, K. D. Plunket, J. L. Shenk, J. B. Stimmel, C. Therapontos, T. M. Willson and S. G. Blanchard. Functional consequences of cysteine modification in the ligand binding sites of peroxisome proliferator activated receptors by GW9662. Biochemistry 41, 6640-50(2002) (Pubitemid 34547354)
40. C. H. Wang, M. K. Ting, S. Verma, L. T. Kuo, N. I. Yang, I. C. Hsieh, S. Y. Wang, A. Hung and W. J. Cherng. Pioglitazone increases the numbers and improves the functional capacity of endothelial progenitor cells in patients with diabetes mellitus. Am Heart J 152, 1051.e1-1051e8(2006)