Expression analyses of human cleft palate tissue suggest a role for osteopontin and immune related factors in palatal development

Experimental and Molecular Medicine

Volumn 41, Issue 2, 2009, Pages 77-85

  Jakobsen, Linda P ^a,b   Borup, Rehannah ^b   Vestergaard, Janni ^a   Larsen, Lars A ^a   Lage, Kasper ^c   Maroun, Lisa Leth ^b   Kjaer, Inger ^a   Niemann, Carsten U ^b   Andersen, Mikael ^b   Knudsen, Mary A ^b   Møllgård, Kjeld ^a   Tommerup, Niels ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b University of Copenhagen   (Denmark)

^c TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

Cleft lip and palate; Congenital abnormalities; Gene expression profiling; Osteopontin; Serglycin

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; OSTEOPONTIN; SERGLYCIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ARTICLE; CHROMOSOMAL LOCALIZATION; CLEFT LIP; CLEFT PALATE; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; NUCLEOTIDE SEQUENCE; PROTEIN FUNCTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; DNA MICROARRAY; GENETICS; IMMUNOLOGY; INFANT; PRENATAL DEVELOPMENT;

CLEFT LIP; CLEFT PALATE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; INFANT; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOPONTIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 63849256443     PISSN: 12263613     EISSN: 20926413     Source Type: Journal    
DOI: 10.3858/emm.2009.41.2.010     Document Type: Article

References (24)

1. Avila JR, Jezewski PA, Vieira AR, Orioli IM, Castilla EE, Christensen K, Daack-Hirsch S, Romitti PA, Murray JC. PVRL1 variants contribute to non-syndromic cleft lip and palate in multiple populations. Am J Med Genet 2006;140:2562-2570
2. Brown NL, Knott L, Halligan E, Yarram SJ, Mansell JP, Sandy JR. Microarray analysis of murine palatogenesis: temporal expression of genes during normal palate development. Dev Growth Differ 2003;45:153-165 (Pubitemid 36566886)
3. Christensen K, Mitchell LE. Familial recurrence-pattern analysis of nonsyndromic isolated cleft palate - a Danish Registry study. Am J Hum Genet 1996;58:182-190
4. Fogh-Andersen P. Inheritance of Harelip and Cleft Palate. Arnold Busck, 1942, Copenhagen
5. Harville EW, Wilcox AJ, Lie RT, Vindenes H, Abyholm F. Cleft lip and palate versus cleft lip only: are they distinct defects? Am J Epidemiol 2005;162:448-453
6. Holladay SD, Sharova LV, Punareewattana K, Hrubec TC, Gogal RM Jr, Prater MR, Sharov AA. Maternal immune stimulation in mice decreases fetal malformations caused by teratogens. Int Immunopharmacol 2002;2:325-332 (Pubitemid 34075421)
7. Jono S, Peinado C, Giachelli CM. Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification. J Biol Chem 2005;275:20197-20203
8. Jugessur A, Murray JC. Orofacial clefting: recent insights into a complex trait. Curr Opin Genet Dev 2005;15:270-278 (Pubitemid 40726050)
9. Kolset SO, Tveit H. Serglycin - structure and biology. Cell Mol Life Sci 2008;65:1073-1085
10. Lage K, Karlberg EO, Storling ZM, Olason PI, Pedersen AG, Rigina O, Hinsby AM, Tümer Z, Pociot F, Tommerup N, Moreau Y, Brunak S. A human phenome-interactome network of protein complexes implicated in genetic disorders. Nat Biotechnol 2007;25:309-316 (Pubitemid 46402863)
11. Li C, Wong WH. Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection. Proc Natl Acad Sci USA 2001;98:31-36 (Pubitemid 32095858)
12. Metneki J, Puho E, Czeizel AE. Maternal diseases and isolated orofacial clefts in Hungary. Birth Defects Res A Clin Mol Teratol 2005;73:617-623 (Pubitemid 41428680)
13. Mukhopadhyay P, Greene RM, Zacharias W, Weinrich MC, Singh S, Young WW Jr, Pisano MM. Developmental gene expression profiling of mammalian, fetal orofacial tissue. Birth Defects Res A Clin Mol Teratol 2004;70:912-926 (Pubitemid 40030368)
14. Murray JC. Gene/environment causes of cleft lip and/or palate. Clin Genet 2002;61:248-256 (Pubitemid 36372641)
15. Niemann CU, Cowland JB, Klausen P, Askaa J, Calafat J, Borregaard N. Localization of serglycin in human neutrophil granulocytes and their precursors. J Leukoc Biol 2004;76:406-415 (Pubitemid 39006955)
16. Rittling SR, Matsumoto HN, McKee MD, Nanci A, An XR, Novick KE, Kowalski AJ, Noda M, Denhardt DT. Mice lacking osteopontin show normal development and bone structure but display altered osteoclast formation in vitro. J Bone Miner Res 1998;13:1101-1111
17. Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M. Towards a proteomescale map of the human protein-protein interaction network. Nature 2005;437:1173-1178 (Pubitemid 41509356)
18. Sharova LV, Gogal RM Jr, Sharov AA, Chrisman MV, Holladay SD. Immune stimulation in urethane-exposed pregnant mice increases expression level of spleen leukocyte genes for TGFbeta3 GM-CSF and other cytokines that may play a role in reduced chemical-induced birth defects. Int Immunopharmacol 2002;2:1477-1489 (Pubitemid 35247970)
19. Suzuki K, Hu D, Bustos T, Zlotogora J, Richieri-Costa A, Helms JA, Spritz RA. Mutations of PVRL1, encoding a cell-cell adhesion molecule/herpesvirus receptor, in cleft lip/palate-ectodermal dysplasia. Nat Genet 2000;25:427-430 (Pubitemid 32983436)
20. Taniguchi T, Takaoka A. The interferon-alpha/beta system in antiviral responses: a multimodal machinery of gene regulation by the IRF family of transcription factors. Curr Opin Immunol 2002;14:111-116 (Pubitemid 34085114)
21. Theocharis AD, Seidel C, Borset M, Dobra K, Baykov V, Labropoulou V, Kanakis I, Dalas E, Karamanos NK, Sundan A, Hjerpe A. Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization in vitro. J Biol Chem 2006;281:35116-35128 (Pubitemid 46036551)
22. Wahl SM, Vazquez N, Chen W. Regulatory T cells and transcription factors: gatekeepers in allergic inflammation. Curr Opin Immunol 2004;16:768-774 (Pubitemid 39423667)
23. Walsh MC, Kim N, Kadono Y, Rho J, Lee SY, Lorenzo J, Choi Y. Osteoimmunology: interplay between the immune system and bone metabolism. Annu Rev Immunol 2006;24:33-63
24. Zucchero TM, Cooper ME, Maher BS, Daack-Hirsch S, Nepomuceno B, Ribeiro L, Caprau D, Christensen K, Suzuki Y, Machida J, Natsume N, Yoshiura K, Vieira AR, Orioli IM, Castilla EE, Moreno L, Arcos-Burgos M, Lidral AC, Field LL, Liu YE, Ray A, Goldstein TH, Schultz RE, Shi M, Johnson MK, Kondo S, Schutte BC, Marazita ML, Murray JC. Interferon regulatory factor 6 (IRF6) gene variants and the risk of isolated cleft lip or palate. N Engl J Med 2004;351:769-780 (Pubitemid 39095312)