Immune stimulation in urethane-exposed pregnant mice increases expression level of spleen leukocyte genes for TGFβ3 GM-CSF and other cytokines that may play a role in reduced chemical-induced birth defects

International Immunopharmacology

Volumn 2, Issue 10, 2002, Pages 1477-1489

  Sharova, L V ^a   Gogal Jr , R M ^a   Sharov, A A ^b   Chrisman, M V ^a   Holladay, S D ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

GM CSF; Immune stimulation; Spleen leukocyte gene; TGF 3; Urethane exposed pregnant mice

Indexed keywords

CYCLOPHOSPHAMIDE; FREUND ADJUVANT; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; GROWTH FACTOR; INTERLEUKIN 2; SOMATOMEDIN B; SOMATOMEDIN C; TERATOGENIC AGENT; TRANSFORMING GROWTH FACTOR BETA3; URETHAN; CYTOKINE; IMMUNOLOGICAL ADJUVANT; MEMBRANE ANTIGEN; TGFB3 PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BIRTH DEFECT; CELL CYCLE; CELL DIFFERENTIATION; CLEFT PALATE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOWN REGULATION; FEMALE; GENE EXPRESSION; IMMUNE SYSTEM; IMMUNOSTIMULATION; MACROPHAGE; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PLACENTA; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; SPLEEN; T LYMPHOCYTE; THYMUS; ANIMAL; BREEDING; CONGENITAL MALFORMATION; DNA MICROARRAY; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INSTITUTE FOR CANCER RESEARCH MOUSE; LYMPHOCYTE COUNT; PREGNANCY;

ABNORMALITIES, DRUG-INDUCED; ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, SURFACE; CYTOKINES; FEMALE; GENE EXPRESSION REGULATION; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; LYMPHOCYTE COUNT; MALE; MICE; MICE, INBRED ICR; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; PREGNANCY, ANIMAL; THYMUS GLAND; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA3; URETHANE;

EID: 0036710890     PISSN: 15675769     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1567-5769(02)00094-2     Document Type: Article

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