Induction and effector phase of allergic lung inflammation is independent of 0121/0119 and LT-beta

International Journal of Medical Sciences

Volumn 6, Issue 2, 2009, Pages 85-92

  Ploix, Corinne ^a   Zuberi, Riaz I ^b   Liu, Fu Tong ^c   Carson, Monica J ^d   Lo, David D ^d  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b LA JOLLA INSTITUTE FOR MOLECULAR MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Asthma; Chemokine; Dendritic cell; Th2

Indexed keywords

CD11 ANTIGEN; LYMPHOTOXIN BETA; MACROPHAGE INFLAMMATORY PROTEIN 3BETA; SECONDARY LYMPHOID TISSUE CHEMOKINE;

AIRWAY RESISTANCE; ALLERGIC LUNG INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTING CELL; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL INFILTRATION; CELL TRANSFER; DENDRITIC CELL; EOSINOPHILIA; MOUSE; NONHUMAN; PNEUMONIA; PROTEIN FUNCTION; TH2 CELL;

EID: 63549128344     PISSN: None     EISSN: 14491907     Source Type: Journal    
DOI: 10.7150/ijms.6.85     Document Type: Article

References (46)

1. Alimzhanov MB, Kuprash DV, Kosco-Vilbois MH, Luz A, Turetskaya RL, Tarakhovsky A, Rajewsky K, Nedospasov SA, Pfeffer K. Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice. Proc Natl Acad Sci USA 1997; 94:9302-7.
2. Gunn MD, Kyuwa S, Tam C, Kakiuchi T, Matsuzawa A, Williams LT, Nakano H. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J Exp Med 1999; 189: 451-60.
3. Cyster JG. Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs. J Exp Med 1999; 189: 447-50.
4. Lucas R, Tacchini-Cottier F, Guler R, Vesin D, Jemelin S, Olleros ML, Marchal G, Browning JL, Vassalli P, Garcia I. A role for lymphotoxin beta receptor in host defense against Mycobacte- rium bovis BCG infection. Eur J Immunol 1999; 29: 4002-10.
5. Berger DP, Naniche D, Crowley MT, Koni PA, Flavell RA, Old-stone MB. Lymphotoxin-beta-deficient mice show defective antiviral immunity. Virology 1999; 260: 136-47.
6. Futterer A, Mink K, Luz A, Kosco-Vilbois MH, Pfeffer K. The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 1998; 9:59-70.
7. Mori S, Nakano H, Aritomi K, Wang CR, Gunn MD, Kakiuchib T. Mice lacking expression of the chemokines CC21-ser and CCL19 (plt mice) demonstrate delayed but enhanced T cell immune responses. J Exp Med 2001; 193: 207-18.
8. Tamada K, Tamura H, Flies D, Fu YX, Celis E, Pease LR, Blazar BR, Chen L. Blockade of LIGHT/LTbeta and CD40 signaling induces allospecific T cell anergy, preventing graft-versus-host disease. J Clin Invest 2002; 109: 549-57.
9. Wu Q, Fu YX, Sontheimer RD. Blockade of lymphotoxin sig- nalin inhibits the clinical expression of murine graft-versus-host skin disease. J Immunol 2004; 172: 1630-6.
10. Mackay F, Browning JL, Lawton P, Shah SA, Comiskey M, Bhan AK, Mizoguchi E, Terhorst C, Simpson SJ. Both the lym- photoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis. Gastroenterology 1998; 115: 1464-75.
11. Stopfer P, Obermeier F, Dunger N, Falk W, Farkas S, Janotta M, Moller A, Mannel DN, Hehlgans T. Blocking lymphotoxin-beta receptor activation diminishes inflammation via reduced mu- cosal addressin cell adhesion molecule-1 (MAdCAM-1) expression and leucocyte margination in chronic DSS-induced colitis. Clin Exp Immunol 2004; 136: 21-9.
12. Wu Q, Salomon B, Chen M, Wang Y, Hoffman LM, Bluestone JA, Fu YX. Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor. J Exp Med 2001; 193: 1327-32.
13. Hjelmstrom P, Fjell J, Nakagawa T, Sacca R, Cuff CA, Ruddle NH. Lymphoid tissue homing chemokines are expressed in chronic inflammation. Am J Pathol 2000; 156: 1133-8.
14. Grant AJ, Goddard S, Ahmed-Choudhury J, Reynolds G, Jackson DG, Briskin M, Wu L, Hubscher SG, Adams DH. Hepatic expression of secondary lymphoid chemokine (CCL21) promotes the development of portal-associated lymphoid tissue in chronic inflammatory liver disease. Am J Pathol 2002; 160:1445-55.
15. Bonacchi A, Petrai I, Defranco RM, Lazzeri E, Annunziato F, Efsen E, Cosmi L, Romagnani P, Milani S, Failli P, Batignani G, Liotta F, Laffi G, Pinzani M, Gentilini P, Marra F. The chemokine CCL21 modulates lymphocyte recruitment and fi- brosis in chronic hepatitis C. Gastroenterology 2003; 125:1060-76.
16. Pashenkov M, Soderstrom M, Link H. Secondary lymphoid organ chemokines are elevated in the cerebrospinal fluid during central nervous system inflammation. J Neuroimmunol 2003; 135: 154-60.
17. Alt C, Lashinger M, Engelhardt B. Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephalo-myelitis. Eur J Immunol 2002; 32: 2133-44.
18. Columba-Cabezas S, Serafini B, Ambrosini E, Aloisi F. Lym- phoid chemokines CCL19 and CCL21 are expressed in the central nervous system during experimental autoimmune enceph-alomyelitis: implications for the maintenance of chronic neuroinflammation. Brain Pathol. 2003; 13: 38-51.
19. Weyand CM, Goronzy JJ. Ectopic germinal center formation in rheumatoid synovitis. Ann NY Acad Sci 2003; 987: 140-9.
20. Salomonsson S, Jonsson MV, Skarstein K, Brokstad KA, Hjelm- strom P, Wahren-Herlenius M, Jonsson R. Cellular basis of ec- topic germinal center formation and autoantibody production in the target organ of patients with Sjogren's syndrome. Arthritis Rheum 2003; 48: 3187-201.
21. 2ndKW, Hood AF, Travers JB, Ramsey H, Hromas RA. Endothelial induction of the T-cell chemokine CCL21 in T-cell autoimmune diseases. Blood 2003; 101: 801-6.
22. Mitsui G, Mitsui K, Hirano T, Ohara O, Kato M, Niwano Y. Kinetic profiles of sequential gene expressions for chemokines in mice with contact hypersensitivity. Immunol Lett 2003; 86: 191-7.
23. Eberhard Y, Ortiz S, Ruiz Lascano A, Kuznitzky R, Serra HM. Up-regulation of the chemokine CCL21 in the skin of subjects exposed to irritants. BMC Immunol 2004; 5: 7.
24. Lew W, Bowcock AM, Krueger JG. Psoriasis vulgaris: cutaneous lymphoid tissue supports T-cell activation and "Type 1" inflammatory gene expression. Trends Immunol 2004; 25:295-305.
25. Serra HM, Eberhard Y, Martin AP, Gallino N, Gagliardi J, Baena-Cagnani CE, Lascano AR, Ortiz S, Mariani AL, Uguc- cioni M. Secondary lymphoid tissue chemokine (CCL21) is upregulated in allergic contact dermatitis. Int Arch Allergy Immunol 2004; 133: 64-71.
26. Ploix C, Lo D, Carson MJ. A ligand for the chemokine receptor CCR7 can influence the homeostatic proliferation of CD4 T cells and progression of autoimmunity. J Immunol 2001; 167:6724-6730.
27. Ruddle NH. Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development. Immunol Res 1999; 19: 119-25.
28. Li L, Xia Y, Nguyen A, Feng L, Lo D. Th2-induced eotaxin expression and eosinophilia coexist with Th1 responses at the effector stage of lung inflammation. J Immunol 1998; 161:3128-35.
29. Li L, Crowley M, Nguyen A, Lo D. Ability of a nondepleting anti-CD4 antibody to inhibit Th2 responses and allergic lung inflammation is independent of coreceptor function. J Immunol 1999; 163: 6557-66.
30. Hamelmann E, Schwarze J, Takeda K, Oshiba A, Larsen GL, Irvin CG, Gelfand EW. Noninvasive measurement of airway responsiveness in allergic mice using barometric plethys-mography. Am J Respir Crit Care Med 1997; 156: 766-75.
31. Hansen G, Berry G, DeKruyff RH, Umetsu DT. Allergen-specific Th1 cells fail to counterbalance Th2 cell-induced airway hyperreactivity but cause severe airway inflammation. J Clin Invest 1999; 103: 175-83.
32. Cohn L, Tepper JS, Bottomly K. IL-4-independent induction of airway hyperresponsiveness by Th2, but not Th1, cells. J Immunol 1998; 161: 3813-6.
33. Randolph DA, Stephens R, Carruthers CJ, Chaplin DD. Cooperation between Th1 and Th2 cells in a murine model of eosi-nophilic airway inflammation. J Clin Invest; 104: 1021-9.
34. Sallusto F, Lanzavecchia A. Mobilizing dendritic cells for tolerance, priming, and chronic inflammation. J Exp Med 1999;189: 611-4.
35. Crowley M, Lo D. Targeted gene knockouts: Insights into dendritic cell biology. In: Lotze M.T., Thomson A.W., eds. Dendritic cells: Biology and clinical application. San Diego: Academic Press. 1999: 579-593.
36. McWilliam AS, Napoli S, Marsh AM, Pemper FL, Nelson DJ, Pimm CL, Stumbles PA, Wells TN, Holt PG. Dendritic cells are recruited into the airway epithelium during the inflammatory response to a broad spectrum of stimuli. J Exp Med 1996; 184:2429-32.
37. Holt PG, Haining S, Nelson DJ, Sedgwick JD. Origin and steady-state turnover of class II MHC-bearing dendritic cells in the epithelium of the conducting airways. J Immunol 1994; 153:256-61.
38. Schon-Hegrad MA, Oliver J, McMenamin PG, Holt PG. Studies on the density, distribution, and surface phenotype of intra- epithelial class II major histocompatibility complex antigen (Ia)-bearing dendritic cells (DC) in the conducting airways. J Exp Med 1991; 173:1345-56.
39. Chvatchko Y, Kosco-Vilbois MH, Herren S, Lefort J, Bonnefoy JY. Germinal center formation and local immunoglobulin E (IgE) production in the lung after an airway antigenic challenge. J Exp Med 1996; 184: 2353-60.
40. Gajewska BU, Alvarez D, Vidric M, Goncharova S, Stampfli MR, Coyle AJ, Gutierrez-Ramos J-C, Jordana M. Generation of experimental allergic airways inflammation in the absence of draining lymph nodes. J Clin Invest 2001; 108:577-583.
41. Mathew A, Medoff BD, Carafone AD, Luster AD. Cutting edge: Th2 cell trafficking into the allergic lung is dependent on chemoattractant receptor signaling. J Immunol 2002; 169: 651-655.
42. Yamashita N, Tashimo H, Matsuo Y, Ishida H, Yoshiura K, Sato K, Yamashita N, Kakiuchi T, Ohta K. Role of CCL21 and CCL19 in allergic inflammation in the ovalbumin-specific murine asthmatic model. J Allergy Clin Immunol. 2006; 117:1040-6.
43. Grinnan D, Sung SS, Dougherty JA, Knowles AR, Allen MB, Rose CE 3rd, Nakano H, Gunn MD, Fu SM, Rose CE Jr. Enhanced allergen-induced airway inflammation in paucity of lymph node T cell (plt) mutant mice. J Allergy Clin Immunol 2006; 118:1234-41.
44. Xu B, Aoyama K, Kusumoto M, Matsuzawa A, Butcher EC, Michie SA, Matsuyama T, Takeuchi T. Lack of lymphoid chemokines CCL19 and CCL21 enhances allergic airway in flammation in mice. Int Immunol. 2007; 19:775-84.
45. Takamura K, Fukuyama S, Nagatake T, Kim DY, Kawamura A, Kawauchi H, Kiyono H. Regulatory role of lymphoid chemokine CCL19 and CCL21 in the control of allergic rhinitis. J Immunol. 2007; 179:5897-906.
46. Stumbles PA, Thomas JA, Pimm CL, Lee PT, Venaille TJ, Proksch S, Holt PG. Resting respiratory tract dendritic cells preferentially stimulate T helper cell type 2 (Th2) responses and equire obligatory cytokine signals for induction of Th1 immunity. J Exp Med 1998; 188:2019-31.