In vivo high-resolution imaging of the injured rat spinal cord using a 3.0T clinical MR scanner

Journal of Magnetic Resonance Imaging

Volumn 29, Issue 3, 2009, Pages 725-730

  Sandner, Beatrice ^a   Pillai, Deepu R ^a   Heidemann, Robin M ^b   Schuierer, Gerhard ^c   Mueller, Matthias F ^d   Bogdahn, Ulrich ^a   Schlachetzki, Felix ^a   Weidner, Norbert ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

^b MR Applications Development   (Germany)

^c Institute for Neuroradiology   (Germany)

^d RAPID BIOMEDICAL GMBH   (Germany)

Author keywords

Magnetic resonance imaging; Small animal imaging; Spinal cord injury

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTUSION; EDEMA; FEASIBILITY STUDY; FEMALE; FISCHER 344 RAT; GRAY MATTER; HISTOLOGY; IMAGE QUALITY; IMAGING SYSTEM; IN VIVO STUDY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; RAT; SPINAL CORD HEMORRHAGE; SPINAL CORD INJURY; WHITE MATTER;

ANIMALS; DISEASE MODELS, ANIMAL; FEASIBILITY STUDIES; FEMALE; IMAGING, THREE-DIMENSIONAL; MAGNETIC RESONANCE IMAGING; RATS; RATS, INBRED F344; REPRODUCIBILITY OF RESULTS; SPINAL CORD; SPINAL CORD INJURIES; THORACIC VERTEBRAE;

EID: 63449115818     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.21477     Document Type: Article

References (22)

1. Hadley DM, Teasdale GM. Magnetic resonance imaging of the brain and spine. J Neurol 1988;235:193-206.
2. Manelfe C. Imaging of the spine and spinal cord. Curr Opin Radiol 1991;3:5-15.
3. Bilgen M, Abbe R, Liu SJ, Narayana PA. Spatial and temporal evolution of hemorrhage in the hyperacute phase of experimental spinal cord injury: in vivo magnetic resonance imaging. Magn Reson Med 2000;43:594-600.
4. Ford JC, Hackney DB, Joseph PM, et al. A method for in vivo high resolution MRI of rat spinal cord injury. Magn Reson Med 1994;31:218-223.
5. Fraidakis M, Klason T, Cheng H, Olson L, Spenger C. High-resolution MRI of intact and transected rat spinal cord. Exp Neurol 1998;153:299-312.
6. Fukuoka M, Matsui N, Otsuka T, Murakami M, Seo Y. Magnetic resonance imaging of experimental subacute spinal cord compression. Spine 1998;23:1540-1549.
7. Guizar-Sahagun G, Rivera F, Babinski E, et al. Magnetic resonance imaging of the normal and chronically injured adult rat spinal cord in vivo. Neuroradiology 1994;36:448-452.
8. Metz GA, Curt A, van de Meent H, Klusman I, Schwab ME, Dietz V. Validation of the weight-drop contusion model in rats: a comparative study of human spinal cord injury. J Neurotrauma 2000;17:1-17.
9. Narayana PA, Grill RJ, Chacko T, Vang R. Endogenous recovery of injured spinal cord: longitudinal in vivo magnetic resonance imaging. J Neurosci Res 2004;78:749-759.
10. Ohta K, Fujimura Y, Nakamura M, Watanabe M, Yato Y. Experimental studyon MRI evaluation ofthe course ofcervical spinal cord injury. Spinal Cord 1999;37:580-584.
11. Weber T, Vroemen M, Behr V, et al. In vivo high-resolution MR imaging of neuropathologic changes in the injured rat spinal cord.AJNR Am J Neuroradiol 2006;27:598-604.
12. Bilgen M, Al-Hafez B, Alrefae T, et al. Longitudinal magnetic resonance imaging of spinal cord injury in mouse: changes in signal patterns associated with the inflammatory response. Magn Reson Imaging 2007;25:657-664.
13. Flanders AE, Schaefer DM, Doan HT, Mishkin MM, Gonzalez CF, Northrup BE. Acute cervical spine trauma: correlation of MR imaging findings with degree of neurologic deficit. Radiology 1990;177:25-33.
14. Hackney DB, Asato R, Joseph PM, et al. Hemorrhage and edema in acute spinal cord compression: demonstration by MR imaging. Radiology 1986;161:387-390.
15. Kulkarni MV, McArdle CB, Kopanicky D, et al. Acute spinal cord injury: MR imaging at 1.5T. Radiology 1987;164:837-843.
16. Pfeifer K, Vroemen M, Blesch A, Weidner N. Adult neural progenitor cells provide a permissive guiding substrate for corticospinal axon growth following spinal cord injury. Eur J Neurosci 2004;20:1695-1704.
17. rang P, Muller R, Eljaouhari A, et al. The promotion of oriented axonal regrowth in the injured spinal cord byalginate-based aniso- tropic capillary hydrogels. Biomaterials 2006;27:3560-3569.
18. Deo AA, Grill RJ, Hasan KM, Narayana PA. In vivo serial diffusion tensor imaging of experimental spinal cord injury. J Neurosci Res 2006;83:801-810.
19. Kim JH, Loy DN, Liang HF, Trinkaus K, Schmidt RE, Song SK. Noninvasive diffusion tensor imaging of evolving white matter pathology in a mouse model of acute spinal cord injury. Magn Reson Med 2007;58:253-260.
20. Franconi F, Lemaire L, Marescaux L, Jallet P, Le Jeune JJ. In vivo quantitative microimaging of rat spinal cord at 7T. Magn Reson Med 2000;44:893-898.
21. Callot V, Duhamel G, Cozzone PJ. In vivo mouse spinal cord imaging using echo-planar imaging at 11.75 T. Magma 2007;20:169-173.
22. Bilgen M, Elshafiey I, Narayana PA. In vivo magnetic resonance microscopy of rat spinal cord at 7 T using implantable RF coils. Magn Reson Med 2001;46:1250-1253.