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Volumn 41, Issue 4, 2009, Pages 430-437

The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOSE TISSUE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHROMOSOME SIZE; CONTROLLED STUDY; GENE EXPRESSION; GENE MAPPING; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; GENOME; HEMATOPOIETIC STEM CELL; HYPOTHALAMUS; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL;

EID: 63449086972     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.350     Document Type: Article
Times cited : (103)

References (47)
  • 1
    • 33846614650 scopus 로고    scopus 로고
    • A high-resolution map of segmental DNA copy number variation in the mouse genome
    • Graubert, T.A. et al. A high-resolution map of segmental DNA copy number variation in the mouse genome. PLoS Genet. 3, e3 (2007).
    • (2007) PLoS Genet , vol.3
    • Graubert, T.A.1
  • 2
    • 4444242992 scopus 로고    scopus 로고
    • Genomic segmental polymorphisms in inbred mouse strains
    • Li, J. et al. Genomic segmental polymorphisms in inbred mouse strains. Nat. Genet. 36, 952-954 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 952-954
    • Li, J.1
  • 3
    • 33744455443 scopus 로고    scopus 로고
    • Hotspots for copy number variation in chimpanzees and humans
    • Perry, G.H. et al. Hotspots for copy number variation in chimpanzees and humans. Proc. Natl. Acad. Sci. USA 103, 8006-8011 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 8006-8011
    • Perry, G.H.1
  • 4
    • 33751329250 scopus 로고    scopus 로고
    • Global variation in copy number in the human genome
    • Redon, R. et al. Global variation in copy number in the human genome. Nature 444, 444-454 (2006).
    • (2006) Nature , vol.444 , pp. 444-454
    • Redon, R.1
  • 5
    • 20044371978 scopus 로고    scopus 로고
    • Mapping segmental and sequence variations among laboratory mice using BAC array CGH
    • Snijders, A. et al. Mapping segmental and sequence variations among laboratory mice using BAC array CGH. Genome Res. 15, 302-311 (2005).
    • (2005) Genome Res , vol.15 , pp. 302-311
    • Snijders, A.1
  • 6
    • 38049150491 scopus 로고    scopus 로고
    • A portrait of copy-number polymorphism in Drosophila melanogaster
    • Dopman, E.B. & Hartl, D.L. A portrait of copy-number polymorphism in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 104, 19920-19925 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 19920-19925
    • Dopman, E.B.1    Hartl, D.L.2
  • 7
    • 46249105777 scopus 로고    scopus 로고
    • Natural selection shapes genome-wide patterns of copy-number polymorphism in Drosophila melanogaster
    • Emerson, J.J., Cardoso-Moreira, M., Borevitz, J.O. & Long, M. Natural selection shapes genome-wide patterns of copy-number polymorphism in Drosophila melanogaster. Science 320, 1629-1631 (2008).
    • (2008) Science , vol.320 , pp. 1629-1631
    • Emerson, J.J.1    Cardoso-Moreira, M.2    Borevitz, J.O.3    Long, M.4
  • 8
    • 42649117472 scopus 로고    scopus 로고
    • Distribution and functional impact of DNA copy number variation in the rat
    • Guryev, V. et al. Distribution and functional impact of DNA copy number variation in the rat. Nat. Genet. 40, 538-545 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 538-545
    • Guryev, V.1
  • 9
    • 4444291843 scopus 로고    scopus 로고
    • Detection of large-scale variation in the human genome
    • Iafrate, A.J. et al. Detection of large-scale variation in the human genome. Nat. Genet. 36, 949-951 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 949-951
    • Iafrate, A.J.1
  • 10
    • 3242808027 scopus 로고    scopus 로고
    • Large-scale copy number polymorphism in the human genome
    • Sebat, J. et al. Large-scale copy number polymorphism in the human genome. Science 305, 525-528 (2004).
    • (2004) Science , vol.305 , pp. 525-528
    • Sebat, J.1
  • 11
    • 32844460938 scopus 로고    scopus 로고
    • Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans
    • Aitman, T.J. et al. Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. Nature 439, 851-855 (2006).
    • (2006) Nature , vol.439 , pp. 851-855
    • Aitman, T.J.1
  • 12
    • 50449091647 scopus 로고    scopus 로고
    • Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
    • McCarroll, S.A. et al. Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat. Genet. 40, 1107-1112 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 1107-1112
    • McCarroll, S.A.1
  • 13
    • 0242300619 scopus 로고    scopus 로고
    • α-Synuclein locus triplication causes Parkinson's disease
    • Singleton, A.B. et al. α-Synuclein locus triplication causes Parkinson's disease. Science 302, 841 (2003).
    • (2003) Science , vol.302 , pp. 841
    • Singleton, A.B.1
  • 14
    • 42349088634 scopus 로고    scopus 로고
    • Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia
    • Walsh, T. et al. Rare structural variants disrupt multiple genes in neurodevelopmental pathways in schizophrenia. Science 320, 539-543 (2008).
    • (2008) Science , vol.320 , pp. 539-543
    • Walsh, T.1
  • 15
    • 7744221326 scopus 로고    scopus 로고
    • The Mouse Phenome Project
    • Bogue, M.A. & Grubb, S.C. The Mouse Phenome Project. Genetica. 122, 71-74 (2004).
    • (2004) Genetica , vol.122 , pp. 71-74
    • Bogue, M.A.1    Grubb, S.C.2
  • 16
    • 42449115721 scopus 로고    scopus 로고
    • wuHMM: A robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data
    • Cahan, P. et al. wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data. Nucleic. Acids Res. 36, e41 (2008).
    • (2008) Nucleic. Acids Res , vol.36
    • Cahan, P.1
  • 19
    • 35348988679 scopus 로고    scopus 로고
    • Paired-end mapping reveals extensive structural variation in the human genome
    • Korbel, J.O. et al. Paired-end mapping reveals extensive structural variation in the human genome. Science 318, 420-426 (2007).
    • (2007) Science , vol.318 , pp. 420-426
    • Korbel, J.O.1
  • 20
    • 46249114293 scopus 로고    scopus 로고
    • Mouse segmental duplication and copy number variation
    • She, X., Cheng, Z., Zollner, S., Church, D.M. & Eichler, E.E. Mouse segmental duplication and copy number variation. Nat. Genet. 40, 909-914 (2008).
    • (2008) Nat. Genet , vol.40 , pp. 909-914
    • She, X.1    Cheng, Z.2    Zollner, S.3    Church, D.M.4    Eichler, E.E.5
  • 21
    • 38849101781 scopus 로고    scopus 로고
    • Significant gene content variation characterizes the genomes of inbred mouse strains
    • Cutler, G., Marshall, L.A., Chin, N., Baribault, H. & Kassner, P.D. Significant gene content variation characterizes the genomes of inbred mouse strains. Genome Res. 17, 1743-1754 (2007).
    • (2007) Genome Res , vol.17 , pp. 1743-1754
    • Cutler, G.1    Marshall, L.A.2    Chin, N.3    Baribault, H.4    Kassner, P.D.5
  • 22
    • 35649018206 scopus 로고    scopus 로고
    • Recurrent DNA copy number variation in the laboratory mouse
    • Egan, C.M., Sridhar, S.,Wigler, M. & Hall, I.M. Recurrent DNA copy number variation in the laboratory mouse. Nat. Genet. 39, 1384-1389 (2007).
    • (2007) Nat. Genet , vol.39 , pp. 1384-1389
    • Egan, C.M.1    Sridhar, S.2    Wigler, M.3    Hall, I.M.4
  • 23
    • 38049055222 scopus 로고    scopus 로고
    • Genomic copy number and expression variation within the C57BL/6J inbred mouse strain
    • Watkins-Chow, D.E. & Pavan, W.J. Genomic copy number and expression variation within the C57BL/6J inbred mouse strain. Genome Res. 18, 60-66 (2008).
    • (2008) Genome Res , vol.18 , pp. 60-66
    • Watkins-Chow, D.E.1    Pavan, W.J.2
  • 24
    • 0031731487 scopus 로고    scopus 로고
    • Genomic disorders: Structural features of the genome can lead to DNA rearrangements and human disease traits
    • Lupski, J.R. Genomic disorders: structural features of the genome can lead to DNA rearrangements and human disease traits. Trends Genet. 14, 417-422 (1998).
    • (1998) Trends Genet , vol.14 , pp. 417-422
    • Lupski, J.R.1
  • 25
    • 20544462642 scopus 로고    scopus 로고
    • Segmental duplications and copy-number variation in the human genome
    • Sharp, A.J. et al. Segmental duplications and copy-number variation in the human genome. Am. J. Hum. Genet. 77, 78-88 (2005).
    • (2005) Am. J. Hum. Genet , vol.77 , pp. 78-88
    • Sharp, A.J.1
  • 26
    • 44849120649 scopus 로고    scopus 로고
    • Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition
    • Akagi, K., Li, J., Stephens, R.M., Volfovsky, N. & Symer, D.E. Extensive variation between inbred mouse strains due to endogenous L1 retrotransposition. Genome Res. 18, 869-880 (2008).
    • (2008) Genome Res , vol.18 , pp. 869-880
    • Akagi, K.1    Li, J.2    Stephens, R.M.3    Volfovsky, N.4    Symer, D.E.5
  • 27
    • 35848943273 scopus 로고    scopus 로고
    • Chambers, S.M. et al. Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem. Cell 1, 578-591 (2007).
    • Chambers, S.M. et al. Hematopoietic fingerprints: an expression database of stem cells and their progeny. Cell Stem. Cell 1, 578-591 (2007).
  • 28
    • 34548433923 scopus 로고    scopus 로고
    • Genomewide association analysis in diverse inbred mice: Power and population structure
    • McClurg, P. et al. Genomewide association analysis in diverse inbred mice: power and population structure. Genetics 176, 675-683 (2007).
    • (2007) Genetics , vol.176 , pp. 675-683
    • McClurg, P.1
  • 29
    • 44949147109 scopus 로고    scopus 로고
    • Wu, C. et al. Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet. 4, e1000070 (2008).
    • Wu, C. et al. Gene set enrichment in eQTL data identifies novel annotations and pathway regulators. PLoS Genet. 4, e1000070 (2008).
  • 30
    • 11144339384 scopus 로고    scopus 로고
    • Long-range control of gene expression: Emerging mechanisms and disruption in disease
    • Kleinjan, D.A. & van Heyningen, V. Long-range control of gene expression: emerging mechanisms and disruption in disease. Am. J. Hum. Genet. 76, 8-32 (2005).
    • (2005) Am. J. Hum. Genet , vol.76 , pp. 8-32
    • Kleinjan, D.A.1    van Heyningen, V.2
  • 31
    • 20044394908 scopus 로고    scopus 로고
    • Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse
    • Pletcher, M.T. et al. Use of a dense single nucleotide polymorphism map for in silico mapping in the mouse. PLoS Biol. 2, e393 (2004).
    • (2004) PLoS Biol , vol.2
    • Pletcher, M.T.1
  • 32
  • 33
    • 0002294347 scopus 로고
    • A simple sequentially rejective multiple test procedure
    • Holm, S. A simple sequentially rejective multiple test procedure. Scand. J. Stat. 6, 65-70 (1979).
    • (1979) Scand. J. Stat , vol.6 , pp. 65-70
    • Holm, S.1
  • 34
    • 20144383240 scopus 로고    scopus 로고
    • Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'
    • Bystrykh, L. et al. Uncovering regulatory pathways that affect hematopoietic stem cell function using 'genetical genomics'. Nat. Genet. 37, 225-232 (2005).
    • (2005) Nat. Genet , vol.37 , pp. 225-232
    • Bystrykh, L.1
  • 35
    • 0022505464 scopus 로고
    • Isolation of a rat liver delta-aminolevulinate dehydrase (ALAD) cDNA clone: Evidence for unequal ALAD gene dosage among inbred mouse strains
    • Bishop, T.R., Cohen, P.J., Boyer, S.H., Noyes, A.N. & Frelin, L.P. Isolation of a rat liver delta-aminolevulinate dehydrase (ALAD) cDNA clone: evidence for unequal ALAD gene dosage among inbred mouse strains. Proc. Natl. Acad. Sci. USA 83, 5568-5572 (1986).
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 5568-5572
    • Bishop, T.R.1    Cohen, P.J.2    Boyer, S.H.3    Noyes, A.N.4    Frelin, L.P.5
  • 36
    • 0032033108 scopus 로고    scopus 로고
    • Multiple copies of the ALA-D gene are located at the Lv locus in Mus domesticus mice
    • Bishop, T.R., Miller, M.W., Wang, A. & Dierks, P.M. Multiple copies of the ALA-D gene are located at the Lv locus in Mus domesticus mice. Genomics 48, 221-231 (1998).
    • (1998) Genomics , vol.48 , pp. 221-231
    • Bishop, T.R.1    Miller, M.W.2    Wang, A.3    Dierks, P.M.4
  • 37
    • 0037456823 scopus 로고    scopus 로고
    • Genetics of gene expression surveyed in maize, mouse and man
    • Schadt, E.E. et al. Genetics of gene expression surveyed in maize, mouse and man. Nature 422, 297-302 (2003).
    • (2003) Nature , vol.422 , pp. 297-302
    • Schadt, E.E.1
  • 38
    • 28444445972 scopus 로고    scopus 로고
    • Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice
    • Hovatta, I. et al. Glyoxalase 1 and glutathione reductase 1 regulate anxiety in mice. Nature 438, 662-666 (2005).
    • (2005) Nature , vol.438 , pp. 662-666
    • Hovatta, I.1
  • 39
    • 43449127511 scopus 로고    scopus 로고
    • Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6
    • Ohtsuka, M., Inoko, H., Kulski, J.K. & Yoshimura, S. Major histocompatibility complex (Mhc) class Ib gene duplications, organization and expression patterns in mouse strain C57BL/6. BMC Genomics 9, 178 (2008).
    • (2008) BMC Genomics , vol.9 , pp. 178
    • Ohtsuka, M.1    Inoko, H.2    Kulski, J.K.3    Yoshimura, S.4
  • 40
    • 33845871732 scopus 로고    scopus 로고
    • Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus
    • Kumar, P.P. et al. Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nat. Cell Biol. 9, 45-56 (2007).
    • (2007) Nat. Cell Biol , vol.9 , pp. 45-56
    • Kumar, P.P.1
  • 41
    • 29444450702 scopus 로고    scopus 로고
    • Common deletions and SNPs are in linkage disequilibrium in the human genome
    • Hinds, D.A., Kloek, A.P., Jen, M., Chen, X. & Frazer, K.A. Common deletions and SNPs are in linkage disequilibrium in the human genome. Nat. Genet. 38, 82-85 (2006).
    • (2006) Nat. Genet , vol.38 , pp. 82-85
    • Hinds, D.A.1    Kloek, A.P.2    Jen, M.3    Chen, X.4    Frazer, K.A.5
  • 42
    • 33846978695 scopus 로고    scopus 로고
    • Relative impact of nucleotide and copy number variation on gene expression phenotypes
    • Stranger, B.E. et al. Relative impact of nucleotide and copy number variation on gene expression phenotypes. Science 315, 848-853 (2007).
    • (2007) Science , vol.315 , pp. 848-853
    • Stranger, B.E.1
  • 43
    • 44949159619 scopus 로고    scopus 로고
    • The current excitement about copy-number variation: How it relates to gene duplications and protein families
    • Korbel, J.O. et al. The current excitement about copy-number variation: how it relates to gene duplications and protein families. Curr. Opin. Struct. Biol. 18, 366-374 (2008).
    • (2008) Curr. Opin. Struct. Biol , vol.18 , pp. 366-374
    • Korbel, J.O.1
  • 44
    • 14644441018 scopus 로고    scopus 로고
    • The Collaborative Cross, a community resource for the genetic analysis of complex traits
    • Churchill, G.A. et al. The Collaborative Cross, a community resource for the genetic analysis of complex traits. Nat. Genet 36, 1133-1137 (2004).
    • (2004) Nat. Genet , vol.36 , pp. 1133-1137
    • Churchill, G.A.1
  • 45
    • 25844494223 scopus 로고    scopus 로고
    • Analysis of chromosome breakpoints in neuroblastoma at subkilobase resolution using fine-tiling oligonucleotide array CGH
    • Selzer, R.R. et al. Analysis of chromosome breakpoints in neuroblastoma at subkilobase resolution using fine-tiling oligonucleotide array CGH. Genes Chromosom. Cancer 44, 305-319 (2005).
    • (2005) Genes Chromosom. Cancer , vol.44 , pp. 305-319
    • Selzer, R.R.1
  • 46
    • 52449135524 scopus 로고    scopus 로고
    • An imputed genotype resource for the laboratory mouse
    • Szatkiewicz, J.P. et al. An imputed genotype resource for the laboratory mouse. Mamm. Genome 19, 199-208 (2008).
    • (2008) Mamm. Genome , vol.19 , pp. 199-208
    • Szatkiewicz, J.P.1
  • 47
    • 51349155028 scopus 로고    scopus 로고
    • Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes
    • Tian, D. et al. Single-nucleotide mutation rate increases close to insertions/deletions in eukaryotes. Nature 455, 105-108 (2008).
    • (2008) Nature , vol.455 , pp. 105-108
    • Tian, D.1


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