Do the estrogen receptors 1 gene variants influence the temperament and character inventory scores in suicidal attempters and healthy subjects?

American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics

Volumn 150, Issue 3, 2009, Pages 434-438

  Giegling, Ina ^a   Chiesa, Alberto ^b   Calati, Raffaella ^b   Hartmann, Annette M ^a   Möller, Hans Jürgen ^a   De Ronchi, Diana ^b   Rujescu, Dan ^a   Serretti, Alessandro ^b  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

Character; ESR1; Polymorphisms; TCI; Temperament

Indexed keywords

ESTROGEN RECEPTOR; ESTROGEN RECEPTOR 1; UNCLASSIFIED DRUG;

ARTICLE; AVOIDANCE BEHAVIOR; CHARACTER; CONTROLLED STUDY; GENE LINKAGE DISEQUILIBRIUM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; PERSONALITY; PRIORITY JOURNAL; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; SUICIDE ATTEMPT; TEMPERAMENT;

CASE-CONTROL STUDIES; CHARACTER; ESTROGEN RECEPTOR ALPHA; FEMALE; GENETIC VARIATION; HAPLOTYPES; HUMANS; MALE; PERSONALITY INVENTORY; POLYMORPHISM, SINGLE NUCLEOTIDE; SUICIDE; TEMPERAMENT;

EID: 63449086919     PISSN: 15524841     EISSN: 1552485X     Source Type: Journal    
DOI: 10.1002/ajmg.b.30834     Document Type: Article

References (25)

1. Barrett JC, Fry B, Maller J, Daly MJ. 2005. Haploview: Analysis and visualization of LD and haplotype maps. Bioinformatics 21(2):263-265.
2. Cavalli Sforza L. 1994. The history and geography of human genes. Princeton, New Jersey, USA: Princeton University Press.
3. Cloninger CR. 1994. Temperament and personality. Curr Opin Neurobiol 4(2):266-273.
4. Cloninger CR, Przybeck TR, Svrakic DM, Wetzel RD. 1994. The temperament and character inventory (TCI): A guide to its development and use. St. Louis, Missouri: Center for Psychobiology of Personality, Washington University.
5. Cohen J. 1988. Statistical power analysis for the behavioral sciences. Hill-sdale, New Jersey: Lawrence Erlbaum Associates. pp. 8-14.
6. Comings DE, Muhleman D, Johnson P, MacMurray JP. 1999. Potential role of the estrogen receptor gene (ESR1) in anxiety. Mol Psychiatry 4(4):374-377.
7. Eklund M, Hansson L, Bengtsson-Tops A. 2004. The influence of temperament and character on functioning and aspects of psychological health among people with schizophrenia. Eur Psychiatry 19(1): 34-41.
8. Feng J, Yan J, Michaud S, Craddock N, Jones IR, Cook EH Jr, Goldman D, Heston LL, Peltonen L, Delisi LE. et al. 2001. Scanning of estrogen receptor alpha (ERalpha) and thyroid hormone receptor alpha (TRalpha) genes in patients with psychiatric diseases: Four missense mutations identified in ERalpha gene. Am J Med Genet 105(4):369-374.
9. First MB, Spitzer RL, Gibbon M, Williams BW, Benjamin L. 1990. Structured Clinical Interview for DSM-IV Axis II Personality Disorders (SCID-II). New York: Biometrics Research Department, State Psychiatric Institute, New York.
10. First MB, Spitzer RL, Gibbon M, Williams JB. 1995. Structured Clinical Interview for DSM-IV Axis I Disorders-Patient Edition (SCID-I/P, Version 2.0). New York: Biometrics Research Department, State Psychiatric Institute, New York.
11. Giegling I, Hartmann AM, Moller HJ, Rujescu D. 2006. Anger- and aggression-related traits are associated with polymorphisms in the 5- HT-2A gene. J Affect Disorders 96(1-2):75-81.
12. Guillem F, Bicu M, Semkovska M, Debruille JB. 2002. The dimensional symptom structure of schizophrenia and its association with temperament and character. Schizophr Res 56(1-2):137-147.
13. Jones I, Middle F, McCandless F, Coyle N, Robertson E, Brockington I, Lendon C, Craddock N. 2000. Molecular genetic studies of bipolar disorder and puerperal psychosis at two polymorphisms in the estrogen receptor alpha gene (ESR 1). Am J Med Genet 96(6):850-853.
14. Lai IC, Liao DL, Bai YM, Lin CC, Yu SC, Chen JY, Wang YC. 2002. Association study of the estrogen receptor polymorphisms with tardive dyskinesia in schizophrenia. Neuropsychobiology 46(4):173-175.
15. Osterlund MK, Grandien K, Keller E, Hurd YL. 2000. The human brain has distinct regional expression patterns of estrogen receptor? mRNA isoforms derived from alternative promoters. J Neurochem 75(4):1390-1397.
16. Ouyang WC, Wang YC, Hong CJ, Tsai SJ. 2001. Estrogen receptor alpha gene polymorphism in schizophrenia: Frequency, age;1; at onset, symptomatology and prognosis. Psychiatr Genet 11(2):95-98.
17. Perlman WR, Matsumoto M, Beltaifa S, Hyde TM, Saunders RC, Webster MJ, Rubinow DR, Kleinman JE, Weickert CS. 2005. Expression of estrogen receptor alpha exon-deleted mRNA variants in the human and non-human primate frontal cortex. Neuroscience 134(1):81-95.
18. Prichard Z, Jorm AF, Prior M, Sanson A, Smart D, Zhang Y, Huttley G, Easteal S. 2002. Association of polymorphisms of the estrogen receptor gene with anxiety-related traits in children and adolescents: A longitudinal study. Am J Med Genet 114(2):169-176.
19. Rujescu D, Giegling I, Gietl A, Hartmann AM, Moller HJ. 2003. A functional single nucleotide polymorphism (V158M) in the COMT gene is associated with aggressive personality traits. Biol Psychiatry 54(1):34-39.
20. Serretti A, Calati R, Ferrari B, De Ronchi D. 2007a. Personalityand genetics. Current Psychiatry Reviews 3.
21. Serretti A, Calati R, Giegling I, Hartmann AM, Moller HJ, Colombo C, Rujescu D. 2007b. 5-HT2A SNPs and the temperament and character inventory. Prog Neuro-Psychopharmacol Biol Psychiatry 31(6): 1275-1281.
22. StatSoft I. 1995. STATISTICA per Windows. StatSoft Italia srl.
23. Sullivan PF. 2007. Spurious genetic associations. Biol Psychiatry 61(10):1121-1126.
24. Tsai SJ, Wang YC, Hong CJ, Chiu HJ. 2003. Association study of oestrogen receptor alpha gene polymorphism and suicidal behaviours in major depressive disorder. Psychiatr Genet 13(1):19-22.
25. Wittchen H, Zaudig M, Fydrich T. 1997. Strukturiertes Klinisches Interview für DSM-IV, Achse I und II. Göttingen: Hogrefe.