Potential role of the estrogen receptor gene (ESR1) in anxiety

Molecular Psychiatry

Volumn 4, Issue 4, 1999, Pages 374-377

  Comings, D E ^a   Muhleman, D ^a   Johnson, P ^b   MacMurray, J P ^c  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

^b Jerry L Pettis VA Hospital   (United States)

^c LOMA LINDA UNIVERSITY   (United States)

Author keywords

Estrogen; Genetics; Polymorphism; SCL 90

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; HORMONE; NEUROTRANSMITTER;

ADULT; ALLELE; ANXIETY NEUROSIS; ARTICLE; BEHAVIOR; DINUCLEOTIDE REPEAT; GENOTYPE; HORMONE BLOOD LEVEL; HUMAN; HYPOTHESIS; MAJOR CLINICAL STUDY; MALE; PHOBIA; PRIORITY JOURNAL; RECEPTOR GENE; SCORING SYSTEM; STATISTICAL ANALYSIS; SUBSTANCE ABUSE;

EID: 0032861341     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000503     Document Type: Article

References (14)

1. Pert CB. Molecules of Emotion. Schribner: New York. NY, 1997. pp 1-368.
2. Weischer ML. On the antiaggressive effect of lithium, Psychophormacologia 1969; 15: 245-254.
3. Comings DE, Chen C, Wu S, Muhleman D. Association of trinucleotide repeat polymorphisms of the androgen receptor gene (AR) with externalizing disorders (ADHD, CD, ODD, novelty seeking). A study and replication. Mol Psychiatry 1999 (submitted).
4. Ogawa S, Lubahn DB, Korach KS, Pfaff DW, Aggressive behaviors of transgenic estrogen-receptor knockout male mice. Ann N Y Acad Sci 1996; 794: 384-385.
5. Giguere Y, Dodin S, Blather C, Dumon M, Morgan K, Rousseau F. Common polymorphisms in vitamin D receptor and estrogen receptor in the prediction of bone mineral density and stiffness index in a cohort of postmenopausal women. Am J Med Genet 1997; 61: A199.
6. Kobayashi S, Inoue S, Hosoi T, Ouchi Y, Shiraki M, Orimo H. Association of bone mineral density with polymorphism of estrogen receptor gene. J Bone Min Res 1996; 11: 306-311.
7. Ushiyama T, Ueyama H, Inoue K, Nishioka J, Ohkubo J, Hukuda S. Estrogen receptor gene polymorphism and generalized osteoarthritis, J Rheumatology 1998; 25: 134-137.
8. Del Senno L, Aguiari GL, Piva R. Dinucleotide repeat polymorphism in the human estrogen receptor (ESR) gene. Hum Mol Genet 1992; 1: 354.
9. Steer RA, Clark DR, Ranieri WF, Symptom dimensions of the SCL-90R: a test of the tripartate model of anxiety and depression. J Pers Assess 1994; 62: 525-536.
10. Cohen J. Statistical Power Analysis for the Behavioral Sciences. Lawrence Erlbaum: Hillsdale, NJ, 1988. pp 1-567.
11. Comings DE, Polygenic inheritance and micro/minisatellites. Mol Psychiatry 1998; 3: 21-31.
12. Lephout ED, A review of brain aromatase cytochrome P450. Brain Res Brain Res Rev 1996; 22: 1-26.
13. Kass F, Charles E, Klein DF, Cohen P. Discordance between SCL-90 and therapists' psychopathology ratings. Arch Gen Psychiotry 1983; 40: 389-393.
14. Robins LN, Helzer J, Croughan J, Ratclif KS. National Institute of Health diagnostic interview schedule. Arch Gen Psychiatry 1981; 38: 381-389.