Displacement effect during HPLC preparative purification of human insulin

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 877, Issue 11-12, 2009, Pages 1216-1220

  Gusarov, D ^a   Nekipelova, V ^a   Gusarova, V ^a   Lasman, V ^a   Bairamashvili, D ^a  

^a SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

Author keywords

A21 desamidoinsulin; Displacement; Human insulin; Preparative chromatography

Indexed keywords

A21-DESAMIDOINSULIN; DISPLACEMENT; HUMAN INSULIN; MOBILE PHASE; MONOCARBOXYLIC ACIDS; ORGANIC MODIFIERS; PREPARATIVE CHROMATOGRAPHY; REVERSED-PHASE HPLC;

CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ESTERIFICATION; ESTERS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PURIFICATION; SORPTION;

INSULIN;

A21 DESAMIDOINSULIN; CARBOXYLIC ACID; ESTER DERIVATIVE; HUMAN INSULIN; INSULIN DERIVATIVE; ORGANIC COMPOUND; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; COMPETITIVE INHIBITION; DRUG PURIFICATION; DRUG SYNTHESIS; ELUTION; ESTERIFICATION; PRIORITY JOURNAL; RELIABILITY; REPRODUCIBILITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SEPARATION TECHNIQUE;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; HUMANS; HYDROGEN-ION CONCENTRATION; HYPOGLYCEMIC AGENTS; INDICATORS AND REAGENTS; INSULIN;

EID: 63449084925     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2009.02.062     Document Type: Article

References (19)

1. Bairamashvili D.I., and Rabinovich M.L. Biotechnol. J. 2 (2007) 801
2. British Pharmacopoeia 1988, H.M. Stationary Office, London, 1988, p. 312.
3. The United States Pharmacopeia, Philadelphia, PA, USA, 2000 (USP24) (Suppl. 3).
4. Nilsson J., Jonasson P., Samuelsson E., Stahl S., and Uhlen M. J. Biotechnol. 48 (1996) 241
5. Kroeff E.P., Owens R.A., Campbell E.L., Johnson R.D., and Marks H.I. J. Chromatogr. 461 (1989) 45
6. Gusarov D., Lasman V., and Bayramashvili D. J. Chromatogr. B 853 (2007) 354
7. Petrides D., Sapidou E., and Calandranis J. Biotechnol. Bioeng. 48 (1995) 529
8. Degerman M., Jakobsson N., and Nilsson B. J. Chromatogr. A 1162 (2007) 41
9. Gusarov D., Vostrikov V.V., Ruchko E.A., Lasman V.A., Mikhalev A.V., and Bairamashvili D.I. Russ. J. Biotechnol. 2 (2006) 44 (Russian text)
10. L.I. Patrushev, D.I. Bayramashvili, A.I. Miroshnikov, Russ. Fed. Pat. 2267534 (2006).
11. Yomota C., Yoshii Y., Takahata T., and Okada S. J. Chromatogr. A 721 (1996) 89
12. Whittinham J.L., Scott D.J., Chance K., Wilson A., Finch J., Brange J., and Dodson G.G. J. Mol. Biol. 318 (2002) 479
13. Yu C.-M., Chin C.Y., Franses E.I., and Wang N.-H.L. J. Colloid Interface Sci. 299 (2006) 733
14. Wellings D.A. A Practical Handbook of Preparative HPLC (2006), Elsevier, Amsterdam
15. Colin H., and Cox G.B. Large-Scale Liquid Chromatography, Encyclopedia of Separation Science (2000), Elsevier, Acad. Press p. 685
16. Swadesh J.K. HPLC: Practical and Industrial Applications. second ed. (2001), CRC Press, Florida, USA
17. Cox G.B., and Snyder L.R. J. Chromatogr. 590 (1992) 17
18. Horvath C., Nahum A., and Frenz J.H. J. Chromatogr. 218 (1981) 365
19. Vigh Gy., Varga-Puchony Z., Szepesi G., and Gazdag M. J. Chromatogr. 386 (1987) 353