Separation of B-3 monodesamidoinsulin from human insulin by high-performance liquid chromatography under alkaline conditions

Journal of Chromatography A

Volumn 721, Issue 1, 1996, Pages 89-96

  Yomota, Chikako ^a   Yoshii, Yukie ^a   Takahata, Tomoko ^a   Okada, Satoshi ^a  

^a NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HUMAN INSULIN; INSULIN A[21 DEAMIDO]; INSULIN DERIVATIVE; INSULIN[B3 DEAMIDO]; UNCLASSIFIED DRUG;

ARTICLE; DRUG CONTROL; DRUG DEGRADATION; DRUG MIXTURE; HUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; TECHNIQUE; ZONE ELECTROPHORESIS;

EID: 0030033870     PISSN: 00219673     EISSN: None     Source Type: Journal    
DOI: 10.1016/0021-9673(95)00761-X     Document Type: Article

References (9)

1. J. Brange, Galenics of Insulin, Springer, Berlin, 1987, p. 54.
2. US Pharmacopeia XXII Revision, US Pharmacopeial Convention, Rockville, MD, 1990.
3. H.W. Smith, L.M. Atkins, D.A. Brinkley, W.G. Richardson and D.J. Miner, J. Chromatogr., 8 (1985) 419.
4. D.M. Smith, R.M. Veanable and J. Collins, J. Chromatogr. Sci., 23 (1985) 81.
5. B.V. Fisher and D. Smith, J. Pharm. Biomed. Anal., 3 (1986) 377.
6. J. Brange, L. Langkjaer, S. Havelund and E. Sorensen, presented at the XII Congress of the International Diabetes Federation, Spain, 1985.
7. S. Nitta, H. Sasagawa, C. Yomota and S. Okada, Chromatographia, 13 (1992) 339.
8. R.G. Nielsen, G.S. Sittampalam and E.C. Pickard, Anal. Biochem., 177 (1989) 20.
9. Novo Nordisk Pharma, personal communication.