-
1
-
-
0024789208
-
Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells
-
Pelchen-Matthews, A., J. E. Armes, and M. Marsh. 1989. Internalization and recycling of CD4 transfected into HeLa and NIH3T3 cells. EMBO J. 8:3641.
-
(1989)
EMBO J.
, vol.8
, pp. 3641
-
-
Pelchen-Matthews, A.1
Armes, J.E.2
Marsh, M.3
-
2
-
-
0025089942
-
Structural features of the cytoplasmic region of CD4 required for internalization
-
Shin, J., C. Doyle, Z. Yang, D. Kappes, and J. L. Strominger. 1990. Structural features of the cytoplasmic region of CD4 required for internalization. EMBO J. 9:425.
-
(1990)
EMBO J.
, vol.9
, pp. 425
-
-
Shin, J.1
Doyle, C.2
Yang, Z.3
Kappes, D.4
Strominger, J.L.5
-
3
-
-
0025779089
-
Phosphorylation-dependent down-modulation of CD4 requires a specific structure within the cytoplasmic domain of CD4
-
Shin, J., R. L. Dunbrack, Jr., S. Lee, and J. L. Strominger. 1991. Phosphorylation-dependent down-modulation of CD4 requires a specific structure within the cytoplasmic domain of CD4. J. Biol. Chem. 266:10658.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 10658
-
-
Shin, J.1
Dunbrack Jr., R.L.2
Lee, S.3
Strominger, J.L.4
-
4
-
-
0344286482
-
Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation
-
Pitcher, C., S. Honing, A. Fingerhut, K. Bowers, and M. Marsh. 1999. Cluster of differentiation antigen 4 (CD4) endocytosis and adaptor complex binding require activation of the CD4 endocytosis signal by serine phosphorylation. Mol. Biol. Cell 10:677.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 677
-
-
Pitcher, C.1
Honing, S.2
Fingerhut, A.3
Bowers, K.4
Marsh, M.5
-
5
-
-
0027321454
-
Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting
-
Pelchen-Matthews, A., I. J. Parsons, and M. Marsh. 1993. Phorbol ester-induced downregulation of CD4 is a multistep process involving dissociation from p56lck, increased association with clathrin-coated pits, and altered endosomal sorting. J. Exp. Med. 178:1209.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1209
-
-
Pelchen-Matthews, A.1
Parsons, I.J.2
Marsh, M.3
-
6
-
-
0029655728
-
Endocytic and exocytic regulation of CD4 expression and function
-
Marsh, M., and A. Pelchen-Matthews. 1996. Endocytic and exocytic regulation of CD4 expression and function. Curr. Top. Microbiol. Immunol. 205:107.
-
(1996)
Curr. Top. Microbiol. Immunol.
, vol.205
, pp. 107
-
-
Marsh, M.1
Pelchen-Matthews, A.2
-
7
-
-
0028173343
-
The role of Nef in the replication cycle of the human and simian immunodeficiency viruses
-
Cullen, B. R. 1994. The role of Nef in the replication cycle of the human and simian immunodeficiency viruses. Virology 205:1.
-
(1994)
Virology
, vol.205
, pp. 1
-
-
Cullen, B.R.1
-
8
-
-
0025743306
-
Importance of the nef gene for maintenance of high virus loads and for development of AIDS
-
Kestler, H. W., III, D. J. Ringler, K. Mori, D. L. Panicali, P. K. Sehgal, M. D. Daniel, and R. C. Desrosiers. 1991. Importance of the nef gene for maintenance of high virus loads and for development of AIDS. Cell 65:651.
-
(1991)
Cell
, vol.65
, pp. 651
-
-
Kestler III, H.W.1
Ringler, D.J.2
Mori, K.3
Panicali, D.L.4
Sehgal, P.K.5
Daniel, M.D.6
Desrosiers, R.C.7
-
9
-
-
0028804160
-
Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients
-
Deacon, N. J., A. Tsykin, A. Solomon, K. Smith, M. Ludford-Menting, D. J. Hooker, D. A. McPhee, A. L. Greenway, A. Ellett, C. Chatfield, et al. 1995. Genomic structure of an attenuated quasi species of HIV-1 from a blood transfusion donor and recipients. Science 270:988.
-
(1995)
Science
, vol.270
, pp. 988
-
-
Deacon, N.J.1
Tsykin, A.2
Solomon, A.3
Smith, K.4
Ludford-Menting, M.5
Hooker, D.J.6
McPhee, D.A.7
Greenway, A.L.8
Ellett, A.9
Chatfield, C.10
-
10
-
-
0028835788
-
Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
-
Kirchhoff, F., T. C. Greenough, D. B. Brettler, J. L. Sullivan, and R. C. Desrosiers. 1995. Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N. Engl. J. Med. 332:228.
-
(1995)
N. Engl. J. Med.
, vol.332
, pp. 228
-
-
Kirchhoff, F.1
Greenough, T.C.2
Brettler, D.B.3
Sullivan, J.L.4
Desrosiers, R.C.5
-
11
-
-
0033519616
-
Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1: A report from the Sydney Blood Bank Cohort
-
Learmont, J. C., A. F. Geczy, J. Mills, L. J. Ashton, C. H. Raynes-Greenow, R. J. Garsia, W. B. Dyer, L. McIntyre, R. B. Oelrichs, D. I. Rhodes, et al. 1999. Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1: a report from the Sydney Blood Bank Cohort. N. Engl. J. Med. 340:1715.
-
(1999)
N. Engl. J. Med.
, vol.340
, pp. 1715
-
-
Learmont, J.C.1
Geczy, A.F.2
Mills, J.3
Ashton, L.J.4
Raynes-Greenow, C.H.5
Garsia, R.J.6
Dyer, W.B.7
McIntyre, L.8
Oelrichs, R.B.9
Rhodes, D.I.10
-
12
-
-
0025733252
-
Serine phosphorylation-independent down-regulation of cell-surface CD4 by nef
-
Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent down-regulation of cell-surface CD4 by nef. Nature 350:508.
-
(1991)
Nature
, vol.350
, pp. 508
-
-
Garcia, J.V.1
Miller, A.D.2
-
13
-
-
0027158904
-
Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection
-
Benson, R. E., A. Sanfridson, J. S. Ottinger, C. Doyle, and B. R. Cullen. 1993. Downregulation of cell-surface CD4 expression by simian immunodeficiency virus Nef prevents viral super infection. J. Exp. Med. 177:1561.
-
(1993)
J. Exp. Med.
, vol.177
, pp. 1561
-
-
Benson, R.E.1
Sanfridson, A.2
Ottinger, J.S.3
Doyle, C.4
Cullen, B.R.5
-
14
-
-
0027315870
-
CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type I-infected individuals
-
Mariani, R., and J. Skowronski. 1993. CD4 down-regulation by nef alleles isolated from human immunodeficiency virus type I-infected individuals. Proc. Natl. Acad. Sci. USA 90:5549.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 5549
-
-
Mariani, R.1
Skowronski, J.2
-
15
-
-
0033578072
-
Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner
-
Lama, J., A. Mangasarian, and D. Trono. 1999. Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Env incorporation in a Nef- and Vpu-inhibitable manner. Curr. Biol. 9:622.
-
(1999)
Curr. Biol.
, vol.9
, pp. 622
-
-
Lama, J.1
Mangasarian, A.2
Trono, D.3
-
16
-
-
0033578016
-
Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
-
Ross, T. M., A. E. Oran, and B. R. Cullen. 1999. Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein. Curr. Biol. 9:613.
-
(1999)
Curr. Biol.
, vol.9
, pp. 613
-
-
Ross, T.M.1
Oran, A.E.2
Cullen, B.R.3
-
18
-
-
0037127303
-
Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells
-
Cortes, M. J., F. Wong-Staal, and J. Lama. 2002. Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells. J. Biol. Chem. 277:1770.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 1770
-
-
Cortes, M.J.1
Wong-Staal, F.2
Lama, J.3
-
19
-
-
0036231461
-
Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes
-
Lundquist, C. A., M. Tobiume, J. Zhou, D. Unutmaz, and C. Aiken. 2002. Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes. J. Virol. 76:4625.
-
(2002)
J. Virol.
, vol.76
, pp. 4625
-
-
Lundquist, C.A.1
Tobiume, M.2
Zhou, J.3
Unutmaz, D.4
Aiken, C.5
-
20
-
-
0037302331
-
Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis
-
Stoddart, C. A., R. Geleziunas, S. Ferrell, V. Linquist-Stepps, M. E. Moreno, C. Bare, W. Xu, W. Yonemoto, P. A. Bresnahan, J. M. McCune, et al. 2003. Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. J. Virol. 77:2124.
-
(2003)
J. Virol.
, vol.77
, pp. 2124
-
-
Stoddart, C.A.1
Geleziunas, R.2
Ferrell, S.3
Linquist-Stepps, V.4
Moreno, M.E.5
Bare, C.6
Xu, W.7
Yonemoto, W.8
Bresnahan, P.A.9
McCune, J.M.10
-
21
-
-
0028180868
-
Nef induces CD4 endocytosis: Requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain
-
Aiken, C., J. Konner, N. R. Landau, M. E. Lenburg, and D. Trono. 1994. Nef induces CD4 endocytosis: requirement for a critical dileucine motif in the membrane-proximal CD4 cytoplasmic domain. Cell 76:853.
-
(1994)
Cell
, vol.76
, pp. 853
-
-
Aiken, C.1
Konner, J.2
Landau, N.R.3
Lenburg, M.E.4
Trono, D.5
-
22
-
-
0028216346
-
The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef
-
Anderson, S. J., M. Lenburg, N. R. Landau, and J. V. Garcia. 1994. The cytoplasmic domain of CD4 is sufficient for its down-regulation from the cell surface by human immunodeficiency virus type 1 Nef. J. Virol. 68:3092.
-
(1994)
J. Virol.
, vol.68
, pp. 3092
-
-
Anderson, S.J.1
Lenburg, M.2
Landau, N.R.3
Garcia, J.V.4
-
23
-
-
0030614819
-
The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane
-
Mangasarian, A., M. Foti, C. Aiken, D. Chin, J. L. Carpentier, and D. Trono. 1997. The HIV-1 Nef protein acts as a connector with sorting pathways in the Golgi and at the plasma membrane. Immunity 6:67.
-
(1997)
Immunity
, vol.6
, pp. 67
-
-
Mangasarian, A.1
Foti, M.2
Aiken, C.3
Chin, D.4
Carpentier, J.L.5
Trono, D.6
-
25
-
-
0028128822
-
Myristoylation-dependent binding of HIV-1 Nef to CD4
-
Harris, M. P., and J. C. Neil. 1994. Myristoylation-dependent binding of HIV-1 Nef to CD4. J. Mol. Biol. 241:136.
-
(1994)
J. Mol. Biol.
, vol.241
, pp. 136
-
-
Harris, M.P.1
Neil, J.C.2
-
26
-
-
0029795040
-
The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef: Mapping of the Nef binding surface by NMR
-
Grzesiek, S., S. J. Stahl, P. T. Wingfield, and A. Bax. 1996. The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef: mapping of the Nef binding surface by NMR. Biochemistry 35:10256.
-
(1996)
Biochemistry
, vol.35
, pp. 10256
-
-
Grzesiek, S.1
Stahl, S.J.2
Wingfield, P.T.3
Bax, A.4
-
27
-
-
0033013962
-
Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal α helix and proline repeat of Nef selectively regulate MHC-I trafficking
-
Mangasarian, A., V. Piguet, J. K. Wang, Y. L. Chen, and D. Trono. 1999. Nef-induced CD4 and major histocompatibility complex class I (MHC-I) down-regulation are governed by distinct determinants: N-terminal α helix and proline repeat of Nef selectively regulate MHC-I trafficking. J. Virol. 73:1964.
-
(1999)
J. Virol.
, vol.73
, pp. 1964
-
-
Mangasarian, A.1
Piguet, V.2
Wang, J.K.3
Chen, Y.L.4
Trono, D.5
-
28
-
-
0029989195
-
Nef-CD4 physical interaction sensed with the yeast two-hybrid system
-
Rossi, F., A. Gallina, and G. Milanesi. 1996. Nef-CD4 physical interaction sensed with the yeast two-hybrid system. Virology 217:397.
-
(1996)
Virology
, vol.217
, pp. 397
-
-
Rossi, F.1
Gallina, A.2
Milanesi, G.3
-
29
-
-
0035088131
-
Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain
-
Preusser, A., L. Briese, A. S. Baur, and D. Willbold. 2001. Direct in vitro binding of full-length human immunodeficiency virus type 1 Nef protein to CD4 cytoplasmic domain. J. Virol. 75:3960.
-
(2001)
J. Virol.
, vol.75
, pp. 3960
-
-
Preusser, A.1
Briese, L.2
Baur, A.S.3
Willbold, D.4
-
30
-
-
0032488055
-
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
-
Greenberg, M., L. DeTulleo, I. Rapoport, J. Skowronski, and T. Kirchhausen. 1998. A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4. Curr. Biol. 8:1239.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1239
-
-
Greenberg, M.1
DeTulleo, L.2
Rapoport, I.3
Skowronski, J.4
Kirchhausen, T.5
-
31
-
-
0033568211
-
Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4
-
Bresnahan, P. A., W. Yonemoto, and W. C. Greene. 1999. Cutting edge: SIV Nef protein utilizes both leucine- and tyrosine-based protein sorting pathways for down-regulation of CD4. J. Immunol. 163:2977.
-
(1999)
J. Immunol.
, vol.163
, pp. 2977
-
-
Bresnahan, P.A.1
Yonemoto, W.2
Greene, W.C.3
-
32
-
-
0032530773
-
Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity
-
Craig, H. M., M. W. Pandori, and J. C. Guatelli. 1998. Interaction of HIV-1 Nef with the cellular dileucine-based sorting pathway is required for CD4 down-regulation and optimal viral infectivity. Proc. Natl. Acad. Sci. USA 95:11229.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 11229
-
-
Craig, H.M.1
Pandori, M.W.2
Guatelli, J.C.3
-
33
-
-
0038795645
-
Signals for sorting of transmembrane proteins to endosomes and lysosomes
-
Bonifacino, J. S., and L. M. Traub. 2003. Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu. Rev. Biochem. 72:395.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 395
-
-
Bonifacino, J.S.1
Traub, L.M.2
-
34
-
-
1842556279
-
Adaptable adaptors for coated vesicles
-
Robinson, M. S. 2004. Adaptable adaptors for coated vesicles. Trends Cell. Biol. 14:167.
-
(2004)
Trends Cell. Biol.
, vol.14
, pp. 167
-
-
Robinson, M.S.1
-
35
-
-
0030684068
-
Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation
-
Greenberg, M. E., S. Bronson, M. Lock, M. Neumann, G. N. Pavlakis, and J. Skowronski. 1997. Co-localization of HIV-1 Nef with the AP-2 adaptor protein complex correlates with Nef-induced CD4 down-regulation. EMBO J. 16:6964.
-
(1997)
EMBO J.
, vol.16
, pp. 6964
-
-
Greenberg, M.E.1
Bronson, S.2
Lock, M.3
Neumann, M.4
Pavlakis, G.N.5
Skowronski, J.6
-
36
-
-
0034713437
-
Interactions of HIV-1 nef with the μ subunits of adaptor protein complexes 1, 2, and 3: Role of the dileucine-based sorting motif
-
Craig, H. M., T. R. Reddy, N. L. Riggs, P. P. Dao, and J. C. Guatelli. 2000. Interactions of HIV-1 nef with the μ subunits of adaptor protein complexes 1, 2, and 3: role of the dileucine-based sorting motif. Virology 271:9.
-
(2000)
Virology
, vol.271
, pp. 9
-
-
Craig, H.M.1
Reddy, T.R.2
Riggs, N.L.3
Dao, P.P.4
Guatelli, J.C.5
-
37
-
-
0346102461
-
Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ-σ1 and AP-3 δ-σ3 hemi-complexes
-
Janvier, K., Y. Kato, M. Boehm, J. R. Rose, J. A. Martina, B. Y. Kim, S. Venkatesan, and J. S. Bonifacino. 2003. Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 γ-σ1 and AP-3 δ-σ3 hemi-complexes. J. Cell Biol. 163:1281.
-
(2003)
J. Cell Biol.
, vol.163
, pp. 1281
-
-
Janvier, K.1
Kato, Y.2
Boehm, M.3
Rose, J.R.4
Martina, J.A.5
Kim, B.Y.6
Venkatesan, S.7
Bonifacino, J.S.8
-
38
-
-
0032488027
-
A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor
-
Bresnahan, P. A., W. Yonemoto, S. Ferrell, D. Williams-Herman, R. Geleziunas, and W. C. Greene. 1998. A dileucine motif in HIV-1 Nef acts as an internalization signal for CD4 downregulation and binds the AP-1 clathrin adaptor. Curr. Biol. 8:1235.
-
(1998)
Curr. Biol.
, vol.8
, pp. 1235
-
-
Bresnahan, P.A.1
Yonemoto, W.2
Ferrell, S.3
Williams-Herman, D.4
Geleziunas, R.5
Greene, W.C.6
-
39
-
-
0037438349
-
Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling
-
Fragoso, R., D. Ren, X. Zhang, M. W. Su, S. J. Burakoff, and Y. J. Jin. 2003. Lipid raft distribution of CD4 depends on its palmitoylation and association with Lck, and evidence for CD4-induced lipid raft aggregation as an additional mechanism to enhance CD3 signaling. J. Immunol. 170:913.
-
(2003)
J. Immunol.
, vol.170
, pp. 913
-
-
Fragoso, R.1
Ren, D.2
Zhang, X.3
Su, M.W.4
Burakoff, S.J.5
Jin, Y.J.6
-
40
-
-
0033515427
-
Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes
-
Piguet, V., F. Gu, M. Foti, N. Demaurex, J. Gruenberg, J. L. Carpentier, and D. Trono. 1999. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes. Cell 97:63.
-
(1999)
Cell
, vol.97
, pp. 63
-
-
Piguet, V.1
Gu, F.2
Foti, M.3
Demaurex, N.4
Gruenberg, J.5
Carpentier, J.L.6
Trono, D.7
-
41
-
-
0032499675
-
Solution structure of the cytoplasmic domain of the human CD4 glycoprotein by CD and 1H NMR spectroscopy: Implications for biological functions
-
Wray, V., D. Mertins, M. Kiess, P. Henklein, W. Trowitzsch-Kienast, and U. Schubert. 1998. Solution structure of the cytoplasmic domain of the human CD4 glycoprotein by CD and 1H NMR spectroscopy: implications for biological functions. Biochemistry 37:8527.
-
(1998)
Biochemistry
, vol.37
, pp. 8527
-
-
Wray, V.1
Mertins, D.2
Kiess, M.3
Henklein, P.4
Trowitzsch-Kienast, W.5
Schubert, U.6
-
42
-
-
0028843339
-
Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail
-
Salghetti, S., R. Mariani, and J. Skowronski. 1995. Human immunodeficiency virus type 1 Nef and p56lck protein-tyrosine kinase interact with a common element in CD4 cytoplasmic tail. Proc. Natl. Acad. Sci. USA 92:349.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 349
-
-
Salghetti, S.1
Mariani, R.2
Skowronski, J.3
|