메뉴 건너뛰기




Volumn 15, Issue 3, 2004, Pages 240-246

Expression of an interleukin-6 - Interleukin-2 fusion protein (pIL-6-IL-2) in P. pastoris

Author keywords

Fusion protein; Pichia pastoris; Porcine interleukin 2; Porcine interleukin 6

Indexed keywords

GLYCOPROTEIN; GLYCYLGLYCYLGLYCYLGLYCYLSERYLGLUTAMINYLPHENYLALANYLGLYCYLSERYLGLYCYLGLYCINE; HYBRID PROTEIN; INTERLEUKIN 6; INTERLEUKIN 8; METHANOL; PEPTIDE; UNCLASSIFIED DRUG; VACCINE; VETERINARY DRUG;

EID: 6344247478     PISSN: 11485493     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (11)

References (29)
  • 1
    • 0023230069 scopus 로고
    • The IL-2 receptor β chain (p70): Role in mediating signals for LAK, NK, and proliferative activities
    • Siegel JP, Sharon M, Smith PL, Leonard WJ. 1987. The IL-2 receptor β chain (p70): role in mediating signals for LAK, NK, and proliferative activities. Science 238: 75.
    • (1987) Science , vol.238 , pp. 75
    • Siegel, J.P.1    Sharon, M.2    Smith, P.L.3    Leonard, W.J.4
  • 2
    • 0023907493 scopus 로고
    • Interleukin-2: Inception, impact, and implications
    • Smith KA. 1988. Interleukin-2: inception, impact, and implications. Science 240: 1169.
    • (1988) Science , vol.240 , pp. 1169
    • Smith, K.A.1
  • 3
    • 0027511151 scopus 로고
    • Recombinant human interleukin 2 induces proliferation and immunoglobulin secretion by bovine B-cells: Tissue differences and preferential enhancement of immunoglobulin A
    • Collins RA, Oldham G. 1993. Recombinant human interleukin 2 induces proliferation and immunoglobulin secretion by bovine B-cells: tissue differences and preferential enhancement of immunoglobulin A. Vet Immunol Immunopathol 36: 31.
    • (1993) Vet Immunol Immunopathol , vol.36 , pp. 31
    • Collins, R.A.1    Oldham, G.2
  • 4
    • 0027421831 scopus 로고
    • Interleukin-6 in biology and medicine
    • Akira S, Taga T, Kishimoto T. 1993. Interleukin-6 in biology and medicine. Adv Immunol 54: 1.
    • (1993) Adv Immunol , vol.54 , pp. 1
    • Akira, S.1    Taga, T.2    Kishimoto, T.3
  • 5
    • 0008925462 scopus 로고    scopus 로고
    • Biology and characterization of hematopoietic cytokines
    • Chapman, Hall Eds, New York
    • Silvennoinnson O, Ihne JN. 1996. Biology and characterization of hematopoietic cytokines. In: Chapman, Hall Eds. The hematopoietic cytokine receptors, New York: 13.
    • (1996) The Hematopoietic Cytokine Receptors , pp. 13
    • Silvennoinnson, O.1    Ihne, J.N.2
  • 8
    • 0030940081 scopus 로고    scopus 로고
    • The anti-human tumor effect and generation of human cytotoxic T cells in SCID mice given human peripheral blood lymphocytes by the in vivo transfer of the Interleukin-6 gene using adenovirus vector
    • Tanaka F, Abe M, Akiyoshi T, Nomura T, Sugimachi K, Kishimoto T, Suzuki T, Okada M. 1997. The anti-human tumor effect and generation of human cytotoxic T cells in SCID mice given human peripheral blood lymphocytes by the in vivo transfer of the Interleukin-6 gene using adenovirus vector. Cancer Res 57: 1335.
    • (1997) Cancer Res , vol.57 , pp. 1335
    • Tanaka, F.1    Abe, M.2    Akiyoshi, T.3    Nomura, T.4    Sugimachi, K.5    Kishimoto, T.6    Suzuki, T.7    Okada, M.8
  • 9
    • 0023847979 scopus 로고
    • B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes
    • Takai Y, Wang GG, Clark SC, Burakoff SJ, Hermann SH. 1988. B cell stimulatory factor-2 is involved in the differentiation of cytotoxic T lymphocytes. J Immunol 140: 508.
    • (1988) J Immunol , vol.140 , pp. 508
    • Takai, Y.1    Wang, G.G.2    Clark, S.C.3    Burakoff, S.J.4    Hermann, S.H.5
  • 10
    • 0028062060 scopus 로고
    • Cytokines as potential Vaccine Adjuvants
    • Nohria A, Rubin RH. 1994. Cytokines as potential Vaccine Adjuvants. Biotherapy 7: 261-269.
    • (1994) Biotherapy , vol.7 , pp. 261-269
    • Nohria, A.1    Rubin, R.H.2
  • 12
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. 1. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. 1986. Two types of murine helper T cell clone. 1. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136 (7): 2348.
    • (1986) J Immunol , vol.136 , Issue.7 , pp. 2348
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 13
    • 0033563011 scopus 로고    scopus 로고
    • The absence of IL-6 does not affect Th2 cell development in vivo, but does lead to impaired proliferation, IL-2 receptor expression, and B cell responses
    • La Flamme AC, Pearce EJ. 1999. The absence of IL-6 does not affect Th2 cell development in vivo, but does lead to impaired proliferation, IL-2 receptor expression, and B cell responses. J Immunol 162: 5829.
    • (1999) J Immunol , vol.162 , pp. 5829
    • La Flamme, A.C.1    Pearce, E.J.2
  • 14
    • 14744299579 scopus 로고
    • Recent advances in the expression of foreign genes in Pichia pastoris
    • Cregg JM, Vedick TS, and Raschke WC. 1993. Recent advances in the expression of foreign genes in Pichia pastoris. Biotechnology 11:905.
    • (1993) Biotechnology , vol.11 , pp. 905
    • Cregg, J.M.1    Vedick, T.S.2    Raschke, W.C.3
  • 15
    • 0002184856 scopus 로고
    • Strategies for optimizing protein expression and secretion in the methylotrophic yeast Pichia pastoris
    • Baltz, R., Hegeman, G. and Skatrud, P. Eds. American Society for Microbiology, Washington, DC
    • Sreekrishna K. 1993. Strategies for optimizing protein expression and secretion in the methylotrophic yeast Pichia pastoris. In: Baltz, R., Hegeman, G. and Skatrud, P. Eds. Industrial microorganisms: basic and applied molecular genetics. American Society for Microbiology, Washington, DC: 119.
    • (1993) Industrial Microorganisms: Basic and Applied Molecular Genetics , pp. 119
    • Sreekrishna, K.1
  • 17
    • 6344253435 scopus 로고    scopus 로고
    • Rapid preparation of PCR template of Saccharomyces cerevislae plasmid and genomic DNA
    • Liu QY, Luo X, He KZ, Li BJ. 2001. Rapid preparation of PCR template of Saccharomyces cerevislae plasmid and genomic DNA. Microbiolgoy 28 (5): 77.
    • (2001) Microbiolgoy , vol.28 , Issue.5 , pp. 77
    • Liu, Q.Y.1    Luo, X.2    He, K.Z.3    Li, B.J.4
  • 18
    • 0038010152 scopus 로고    scopus 로고
    • Expression, purification, and characterization of recombinant human neurturin secreted from the yeast Pichia pastoris
    • Li HJ, Ma YB, Su T, Che YC, Dai C, Sun M. 2003. Expression, purification, and characterization of recombinant human neurturin secreted from the yeast Pichia pastoris. Pro Exp Pur 30: 11.
    • (2003) Pro Exp Pur , vol.30 , pp. 11
    • Li, H.J.1    Ma, Y.B.2    Su, T.3    Che, Y.C.4    Dai, C.5    Sun, M.6
  • 19
    • 6344233923 scopus 로고    scopus 로고
    • The introduction of interleukin-2 and interleukin-6
    • Sun WM, Wang HQ Eds. People's medical publishing house. Beijing, China
    • Sun WM, Wang HQ. 1997. The introduction of interleukin-2 and interleukin-6. In: Sun WM, Wang HQ Eds. The methods of cytokine research. People's medical publishing house. Beijing, China.
    • (1997) The Methods of Cytokine Research
    • Sun, W.M.1    Wang, H.Q.2
  • 21
    • 0033955337 scopus 로고    scopus 로고
    • Heterologous protein expression in the methylotrophic yeast Pichia pastoris
    • Cereghino JL, Cregg JM. 2000. Heterologous protein expression in the methylotrophic yeast Pichia pastoris. FEMS Microbiol Rev 24(1): 45
    • (2000) FEMS Microbiol Rev , vol.24 , Issue.1 , pp. 45
    • Cereghino, J.L.1    Cregg, J.M.2
  • 22
    • 0003149190 scopus 로고
    • Protocol for efficient secretion of HAS developed from Pichia pastoris
    • Barr KA, Hopkins SA, Sreekrishna K. 1992. Protocol for efficient secretion of HAS developed from Pichia pastoris. Pharm Eng 1248.
    • (1992) Pharm Eng , pp. 1248
    • Barr, K.A.1    Hopkins, S.A.2    Sreekrishna, K.3
  • 23
    • 15444377148 scopus 로고
    • Yeast systems for the commercial production of heterologous proteins
    • Buckholz RG, Gleeson MAG. 1991. Yeast systems for the commercial production of heterologous proteins. Bio & Techonlogy 9: 1067.
    • (1991) Bio & Techonlogy , vol.9 , pp. 1067
    • Buckholz, R.G.1    Gleeson, M.A.G.2
  • 24
    • 0034702793 scopus 로고    scopus 로고
    • Expression of a TGF-β superfamily protein, macrophage inhibitory cytokines-1 in the yeast Pichia pastoris
    • Fairlie WD, Zhang HP, Brown PK, Russell PK, Bauskin AR, Breit SN. 2000. Expression of a TGF-β superfamily protein, macrophage inhibitory cytokines-1 in the yeast Pichia pastoris. Gene 254: 67.
    • (2000) Gene , vol.254 , pp. 67
    • Fairlie, W.D.1    Zhang, H.P.2    Brown, P.K.3    Russell, P.K.4    Bauskin, A.R.5    Breit, S.N.6
  • 25
    • 0032029756 scopus 로고    scopus 로고
    • Expression of human interleukin-17 in Pichia pastoris: Purification and characterization
    • Murphy KP Jr, Gagne P, Pazmany C, Moody MD. 1998. Expression of human interleukin-17 in Pichia pastoris: purification and characterization. Pro Exp Puri 12: 208.
    • (1998) Pro Exp Puri , vol.12 , pp. 208
    • Murphy Jr., K.P.1    Gagne, P.2    Pazmany, C.3    Moody, M.D.4
  • 26
    • 0026094226 scopus 로고
    • Production of mouse epidermal growth factor in yeast: High-level secretion using Pichia pastoris strains containing multiple gene copies
    • Clare JJ, Romanes MA, Rayment FB, Rowedder JE, Smith MA, Payne MM, Sreekrishna K, Henwood CA. 1991. Production of mouse epidermal growth factor in yeast: high-level secretion using Pichia pastoris strains containing multiple gene copies. Gene 105: 205.
    • (1991) Gene , vol.105 , pp. 205
    • Clare, J.J.1    Romanes, M.A.2    Rayment, F.B.3    Rowedder, J.E.4    Smith, M.A.5    Payne, M.M.6    Sreekrishna, K.7    Henwood, C.A.8
  • 27
    • 0024505731 scopus 로고
    • High level expression, purification and characterization of recombinant human tumor necrosis factor synthesized in the methylotrophic yeast Pichia pastoris
    • Sreekrishna K, Nelles L, Potenz R, Cruze J, Mazzaferro P, Fish W, Fuke M, Holden K, Phelps D, Wood P. 1989. High level expression, purification and characterization of recombinant human tumor necrosis factor synthesized in the methylotrophic yeast Pichia pastoris. Biochemistry 28: 4117.
    • (1989) Biochemistry , vol.28 , pp. 4117
    • Sreekrishna, K.1    Nelles, L.2    Potenz, R.3    Cruze, J.4    Mazzaferro, P.5    Fish, W.6    Fuke, M.7    Holden, K.8    Phelps, D.9    Wood, P.10
  • 28
    • 6344259012 scopus 로고    scopus 로고
    • Construction of expression vector of secretory rhGM-CSF/IL-2 fusion protein
    • Liu DM, Zhang ZY, Wang Y. 2002. Construction of expression vector of secretory rhGM-CSF/IL-2 fusion protein. Chi J Bio 15(4): 197.
    • (2002) Chi J Bio , vol.15 , Issue.4 , pp. 197
    • Liu, D.M.1    Zhang, Z.Y.2    Wang, Y.3
  • 29
    • 0032878101 scopus 로고    scopus 로고
    • Rat tumour necrosis factor-alpha: Expression in recombinant Pichia pastoris, purification, characterisation, and development of a novel ELISA
    • Rees GS, Gee CK, Ward HL, Ball C, Tarrant GM, Poole S, Bristow AF. 1999. Rat tumour necrosis factor-alpha: expression in recombinant Pichia pastoris, purification, characterisation, and development of a novel ELISA. Eur Cyt Net 10 (3): 383.
    • (1999) Eur Cyt Net , vol.10 , Issue.3 , pp. 383
    • Rees, G.S.1    Gee, C.K.2    Ward, H.L.3    Ball, C.4    Tarrant, G.M.5    Poole, S.6    Bristow, A.F.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.