Extragonadal luteinizing hormone receptors in the reproductive tract of domestic animals

Biology of Reproduction

Volumn 71, Issue 5, 2004, Pages 1412-1418

  Fields, Michael J ^a   Shemesh, Mordechai ^b  

^a UNIVERSITY OF FLORIDA   (United States)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Cervix; Female reproductive tract; Luteinizing hormone; Oviduct; Uterus

Indexed keywords

LUTEINIZING HORMONE RECEPTOR; MESSENGER RNA; PROSTAGLANDIN F2 ALPHA;

CATTLE; ENDOMETRIUM; ESTRUS CYCLE; HORMONAL REGULATION; HUMAN; IMMUNOHISTOCHEMISTRY; MYOMETRIUM; NIDATION; NONHUMAN; OVIDUCT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR DENSITY; SHEEP; SHORT SURVEY; SPECIES DIFFERENCE; SWINE; UTERINE CERVIX;

ANIMALS; ANIMALS, DOMESTIC; CERVIX UTERI; ENDOMETRIUM; FALLOPIAN TUBES; FEMALE; GENITALIA, FEMALE; HUMANS; MICE; MICE, KNOCKOUT; MYOMETRIUM; RECEPTORS, LH;

ANIMALIA; BOS TAURUS; BOVINAE; OVIS; OVIS ARIES; PRIMATES; SUIDAE; SUS SCROFA;

EID: 6344246231     PISSN: 00063363     EISSN: None     Source Type: Journal    
DOI: 10.1095/biolreprod.104.027201     Document Type: Short Survey

References (85)

1. Pierce J, Parsons T. Glycoprotein hormones: structure and function. Annu Rev Biochem 1981; 50:465-495.
2. Catt K, Dufau ML. Gonadotropic hormones: biosynthesis secretion, receptors and actions. In: Yen SCC, Jeffe RB (eds.), Reproductive Endocrinology. Philadelphia: Saunders; 1991:105-155.
3. Huhtaniemi IT, Catt KJ. Differential binding affinities of rat testis luteinizing hormone (LH) receptors for human chorionic gonadotropin, human LH, and ovine LH. Endocrinology 1981; 108:1931-1938.
4. Csapo AI, Pulkkinen MO, Runner B, Savauge JP, Wiest WG. The significance of the human corpus luteum in pregnancy maintenance. I. Preliminary studies. Am J Obstet Gynecol 1972; 112:1061-1067.
5. Lei ZM, Toth P, Rao ChV, Pridham D. Novel coexpression of human chorionic gonadotropin (hCG)/human luteinizing hormone receptors and their ligand hCG in human fallopian tubes. J Clin Endocrinol Metab 1993; 77:863-872.
6. Han SW, Lei ZM, Rao ChV. Up-regulation of cyclooxygenase-2 gene expression by chorionic gonadotropin in mucosal cells from human fallopian tubes. Endocrinology 1996; 137:2929-2937.
7. Sun T, Lei ZM, Rao ChV. A novel regulation of the oviductal glycoprotein gene expression by luteinizing hormone in bovine tubal epithelial cells. Mol Cell Endo 1997; 131:97-108.
8. Mishra S, Lei ZM, Rao ChV. A novel role of luteinizing hormone in the embryo development in cocultures. Biol Reprod 2003; 68:1455-1462.
9. Derecka K, Pietila EM, Rajaniemi HJ, Ziecik AJ. Cycle-dependent LH/hCG receptor gene expression in porcine nongonadal reproductive tissues. J Physiol Pharmacol 1995; 46:77-85.
10. Gawronska B, Paukku T, Huhtaniemi I, Wasowicz G, Ziecik AJ. Estrogen-dependent expression of LH/hCG receptors in pig fallopian tube and their role in relaxation of the oviduct. J Reprod Fertil 1999; 115:293-301.
11. Gawronska B, Stepien A, Ziecik AJ. Effect of estradiol and progesterone on oviductal LH-receptors and LH-dependent relaxation of the porcine oviduct. Theriogenology 2000; 53:659-672.
12. Gawronska B, Stepien A, Ziecik AJ. Role of luteinizing hormone in control of oviduct function. Reprod Domest Anim 2000; 35:129-133.
13. You S, Kim H, Hsu CC, El Halawani ME, Foster DN. Three different turkey luteinizing hormone receptor (tLH-R) isoforms 1: characterization of alternative spliced tLH-R isoforms and their regulated expression in diverse tissues. Biol Reprod 2000; 62:108-116.
14. Zheng M, Shi H, Segaloff DL, Van Voorhis BJ. Expression and localization of luteinizing hormone receptor in the female mouse reproductive tract. Biol Reprod 2001; 64:179-187.
15. Woodruff JD, Pauerstein CJ. The Fallopian Tube: Structure, Function, Pathology and Management. Baltimore: Williams and Wilkins; 1969.
16. Wijayagunawardane MPB, Miyamoto A, Taquahashi Y, Gabler C, Acosta TJ, Nishimura M, Killian G, Sato K. In vitro regulation of local secretion and contraction of the bovine oviduct: stimulation by luteinizing hormone, endothelin-1 and prostaglandins and inhibition by oxytocin. J Endocrinol 2001; 168:117-130.
17. 2α and endothelin-1 production by cow oviductal epithelial cell monolayers: effect of progesterone, estradiol 17β, oxytocin and luteinizing hormone. Theriogenology 1999; 52:791-801.
18. Nancarrow CD, Hill JL. Oviduct proteins in fertilization and early embryo development. J Reprod Fertil Suppl 1995; 49:3-13.
19. Friedman S, Gurevich M, Shemesh M. Bovine cyclic endometrium contains high-affinity luteinizing hormone/human chorionic gonadotropin binding sites. Biol Reprod 1995; 92:1020-1026.
20. Ziecik AJ, Stanchev PD, Tilton JE. Evidence for the presence of luteinizing hormone/human chorionic gonadotropin-binding sites in the porcine uterus. Endocrinology 1986; 119:1159-1163.
21. Shemesh M, Mizrachi D, Gurevich M, Shore LS, Reed J, Chang SMT, Thatcher WW, Fields MJ. Expression of functional luteinizing hormone (LH) receptor and its messenger ribonucleic acid in bovine endometrium: LH augmentation of cAMP and inositol phosphate in vitro and human chorionic gonadotropin (hCG) augmentation of peripheral prostaglandin in vivo. Reprod Biol 2001; 1:13-32.
22. Stepien A, Derecka K, Gawronska B, Bodek G, Zwierzchowski L, Shemesh M, Ziecik AJ. LH/hCG receptors in the porcine uterus - a new evidence of their presence in the cervix and myometrium. J Physiol Pharmacol 2000; 51:917-931.
23. Rosemblit N, Ascoli M, Segaloff DL. Characterization of an antiserum to the rat luteal luteinizing hormone/chorionic gonadotropin receptor. Endocrinology 1988; 128:2284-2290.
24. Lin J, Lei ZM, Lojun S, Rao ChV, Satyaswaroop PG, Day TG. Increased expression of luteinizing hormone/human chorionic gonadotropin receptor gene in human endometrial carcinomas. J Clin Endocrinol Metab 1994; 79:1483-1491.
25. Han SW, Lei ZM, Rao ChV. Homologous down-regulation of luteinizing hormone/chorionic gonadotropin receptors by increasing the degradation of receptor transcripts in human uterine endometrial stromal cells. Biol Reprod 1997; 57:158-164.
26. Pietila EM, Aatsinki JT, Rajaniemi HJ. Expression of the LH/CG-receptor gene in various rat tissues. J Physiol Pharmacol 1996; 47(suppl 1):5-14.
27. Arosh JA, Parent J, Chapdelaine P, Sirios J, Fortier MA. Expression of cyclooxygenases 1 and 2 and prostaglandin E synthase in bovine endometrial tissue during the estrous cycle. Biol Reprod 2002; 67:161-169.
28. Shemesh M, Gurevich M, Shore LS, Davidson I, Friedman S, Dombrovski L. Regulation of cyclooxygenase and products of the cyclooxygenase pathway in the bovine uterus. Reprod Domest Anim 1996; 31:431-436.
29. Stepien A, Shemesh M, Ziecik AJ. Luteinizing hormone-receptor kinetic and LH-induced prostaglandin production throughout the estrous cycle in porcine endometrium. J Reprod Nutr Dev 1999; 39:663-674.
30. Shemesh M, Freidman S, Harel-Markowitz E, Gurevich M. Induction and regulation of cyclooxygenase in the bovine endometrium. In: Zor M (ed.), Lipid Mediators in Health and Disease. Tel Aviv, Israel: Freund Publishing House Ltd.; 1994:71-78.
31. Behrman HR. Prostaglandins in hypothalamo-pituitary and ovarian function. Annu Rev Physiol 1979; 41:685-700.
32. Rahe CH, Owens RE, Fleeger JL, Newton HJ, Harms PG. Pattern of plasma luteinizing hormone in the cyclic cow: dependence upon the period of the cycle. Endocrinology 1980; 107:498-503.
33. Canino CJ, Reed J, Shemesh M, Chang SMT, Marion VK, Hiers EA, Binta H, Luce BR, Thatcher WW, Fields MJ. Induction of prostaglandin synthesis via LH/hCG receptors in the bovine uterus. Biol Reprod 1999; 60(suppl 1):262.
34. Ziecik AJ, Kotwica G. Involvement of gonadotropins in induction of luteolysis in pigs. Reprod Biol 2001; 1:33-50.
35. 2α) and progesterone in vitro. Prostaglandins 2003; 71:55-73.
36. Ziecik AJ, Stepien A, Gawronska B. Importance of endometrial luteinizing hormone receptors in induction of luteolysis and maternal recognition of pregnancy in the pig. Reprod Domest Anim 2000; 35:190-192.
37. Ziecik AJ, Derecka K, Gawronska B, Stepien A, Bodek G. Nongonadal LH/hCG receptors in pig: functional importance and parallels to human. Semin Reprod Med 2001; 19:19-30.
38. Zhou X-L, Lei ZM, Rao ChV. Treatment of human endometrial gland epithelial cells with chorionic gonadotropin/luteinizing hormone increases the expression of the cyclooxygenase-2 gene. J Clin Endocrinol Metab 1999; 84:3364-3377.
39. Srisuparp S, Strakova Z, Brudney A, Mukherjee S, Reierstad S, Hunzicker-Dunn M, Fazleabas AT. Signal transduction pathways activated by chorionic gonadotropin in the primate endometrial epithelial cells. Biol Reprod 2003; 68:457-464.
40. Ziecik AJ, Derecka-Reszka KA, Rzucidlo SJ. Extragonadal gonadotropin receptors, their distribution and function. J Physiol Pharmacol 1992; 43(suppl 1):33-49.
41. Ziecik AJ, Jedlinska M, Rzucidlo SJ. Effect of estradiol and progesterone on myometrial LH/hCG receptors in pigs. Acta Endocrinol 1992; 127:185-188.
42. Rzucidlo SJ, Weigl RM, Tilton JE. Myometrial LH/hCG receptors during the estrous cycle and pregnancy in pigs. Anim Reprod Sci 1998; 51:249-257.
43. Bonnamy PJ, Benhaim A, Leymarie P. Human chorionic gonadotropin affects tissue levels of progesterone and cyclic adenosine 3′,5′- monophosphate in the metestrous rat uterus in vitro. Biol Reprod 1989; 40:511-516.
44. Sawitzke AL, Odell WD. Uterine binding sites for LH/hCG can be modulated by hormonal status in rabbits and rats. Acta Endocrinol 1991; 124:322-330.
45. Jensen TD, Odell WD. Identification of LH/hCG receptors in rabbit uterus. Proc Soc Exp Biol Med 1988; 189:28-30.
46. Reshef E, Lei ZM, Rao ChV, Pridham DD, Chegini N, Luborsky JL. The presence of gonadotropin receptors in nonpregnant human uterus, human placenta, fetal membranes, and decidua. J Clin Endocrinol Metab 1990; 70:421-430.
47. Zuo J, Lei ZM, Rao ChV. Human myometrial chorionic gonadotropin/ luteinizing hormone receptors in preterm and term deliveries. J Clin Endocrinol Metab 1994; 79:907-911.
48. Shemesh M, Mizrachi D, Gurevich M, Stram Y, Shore LS, Fields MJ. Functional importance of bovine myometrial and vascular LH receptors and cervical FSH receptors. Semin Reprod Med 2001; 19:87-96.
49. Shemesh M. Actions of gonadotropins on the uterus. Reproduction 2001; 121:835-842.
50. Kornyei JL, Lei ZM, Rao ChV. Human myometrial smooth muscle cells are novel targets of direct regulation by human chorionic gonadotropin. Biol Reprod 1993; 49:1149-1157.
51. Ziecik AJ, Gajewski Z, Jedruch J, Barcikowski B. Effect of human chorionic gonadotropin on myometrial electrical activity in the pig. Anim Reprod Sci 1993; 31:131-139.
52. Flowers B, Ziecik AJ, Caruolo EV. Effects of human chorionic gonadotropin on contractile activity of steroid-primed pig myometrium in vitro. J Reprod Fertil 1991; 92:425-432.
53. Ziecik AJ, Ostrowska G, Kisielewska J, Zezula-Szypyra A. Distribution and cycle phase dependency of gonadotropin receptors in musculature and blood vessels of the porcine broad ligament. Exp Clin Endocrinol Diabetes 1995; 103:44-51.
54. Ziecik AJ, Golba G, Kisielewska J. Effect of human chorionic gonadotropin on uterine blood flow in intact and ovariectomized gilts. Exp Clin Endocrinol Diabetes 1996; 104:158-163.
55. Ford SP. Maternal recognition of pregnancy in the ewe, cow and sow: vascular and immunological aspects. Theriogenology 1985; 23:145-149.
56. Lacroix MC, Kann G. Discriminating analysis of "in vitro" prostaglandin release by myometrial and luminal sides of the ewe endometrium. Prostaglandins 1983; 25:853-869.
57. Shemesh M, Hansel W. Levels of prostaglandin F (PGF) in bovine endometrium, uterine venous, ovarian arterial and jugular plasma during the estrous cycle. Proc Soc Exp Biol Med 1975; 148:123-126.
58. Shemesh M, Freidman S, Gurevich M, Stram Y, Fields M, Shore LS. Luteinizing hormone receptors and its mRNA in the bovine endometrium. J Physiol Pharmacol 1996; 47(suppl 1):15-27.
59. Basu S, Kindahl H. Prostaglandin biosynthesis and its regulation in the bovine endometrium: a comparison between nonpregnant and pregnant status. Theriogenology 1987; 28:175-193.
60. Shemesh M, Gurevich M, Mizrachi D, Dombrovski L, Stram Y, Fields MJ, Shore LS. Expression of functional luteinizing hormone (LH) receptor and its messenger ribonucleic acid in bovine uterine veins: LH induction of cyclooxygenase and augmentation of prostaglandin production in bovine uterine veins. Endocrinology 1997; 138:4844-4851.
61. Chegini N, Lei ZM, Rao ChV, Hansel W. Cellular distribution and cycle phase dependency of gonadotropin and eicosanoid binding sites in bovine corpora lutea. Biol Reprod 1991; 45:506-513.
62. Lei ZM, Reshef E, Rao ChV. The expression of human chorionic gonadotropin/luteinizing hormone receptors in human endometrial and myometrial blood vessels. J Clin Endocrinol Metab 1992; 75:651-659.
63. Toth P, Li X, Rao CV Lincoln SR, Sanfilippo JS, Spinnato JA II, Yussman MA. Expression of functional human chorionic gonadotropin/human luteinizing hormone receptor gene in human uterine arteries. J Clin Endocrinol Metab 1994; 79:307-315.
64. Zondek B, Sulma F, Black R. The hyperemia effect of gonadotropins on the ovary and its use in a rapid pregnancy test. JAMA 1945; 129:939-940.
65. Ellis S. Bioassay of luteinizing hormone. Endocrinology 1961; 68:334-340.
66. Zygmunt M, Herr F, Keller-Schoenwetter S, Kunzi-Rapp K, Munstedt K, Rao CV, Lang U, Preissner KT. Characterization of human chorionic gonadotropin as a novel angiogenic factor. J Clin Endocrinol Metab 2002; 87:5290-5296.
67. Pexton JE, Weems CW, Inskeep EK. Prostaglandin F in uterine venous plasma, ovarian arterial and venous plasma and in ovarian and luteal tissue of pregnant and nonpregnant ewes. J Anim Sci 1975; 41:154-159.
68. 2α and its metabolites in uterine and jugular venous plasma and endometrium of ewes during early pregnancy. J Anim Sci 1977; 45:320-327.
69. Mizrachi D, Shemesh M. Expression of functional luteinizing hormone receptor and its messenger ribonucleic acid in bovine cervix: luteinizing hormone augmentation of intracellular cAMP, phosphate inositol and cyclooxygenase. Mol Cell Endocrinol 1999; 157:191-200.
70. Lin PC, Li X, Lei ZM, Rao ChV. Human cervix contains functional luteinizing hormone/human chorionic gonadotropin receptors. J Clin Endocrinol Metab 2003; 88:3409-3414.
71. Luck MR, Sivester LM, Zhao Y. The role of the extracellular matrix in reproductive tissues. Reprod Domest Anim 1996; 31:403-405.
72. Khalifa RME, Sayre BL, Lewis GS. Exogenous oxytocin dilates the cervix in ewes. J Anim Sci 1992; 70:38-42.
73. 2 into cervical artery. J Reprod Fertil 1983; 69:511-515.
74. 2 gel in pregnant and non-pregnant heifers. Vet Rec 1993; 133:546-549.
75. 2 release from bovine cervical mucosa in vivo. Prostaglandins Other Lipid Mediat 2002; 70:119-129.
76. 2. Prostaglandins 1984; 28:217-227.
77. Keirse MJ. Prostaglandins in preinduction cervical ripening: meta-analysis of worldwide clinical experience. J Reprod Med 1993; 38:89-100.
78. Coleman RA, Kennedy I, Humphrey PPA, Bruce K, Lunden P. Prostanoids and their receptors. In: Hausch C, Sammes PG, Taylor JB (eds.), Comprehensive Medicinal Chemistry. New York: Pergamon Press; 1989:643-714.
79. Kurtzman JT, Spinnato JA, Goldsmith LJ, Zimmerman MJ, Klem M, Lei ZM, Rao ChV. Human chorionic gonadotropin exhibits potent inhibition of preterm delivery in a small animal model. Am J Obstet Gynecol 1999; 181:853-857.
80. Than NG, Itakura A, Rao ChV, Nohira T, Toth P, Mansell JP, Isaka K, Nishi H, Takayama M, Than GN. Clinical applications of pregnancy-related proteins-a workshop report. Placenta 2003; Suppl A:560-564.
81. Lei ZM, Mishra S, Zou W, Xu B, Foltz M, Li X, Rao ChV. Targeted disruption of luteinizing hormone/human chorionic gonadotropin-receptor gene. Mol Endo 2001; 15:184-200.
82. Rao ChV. Multiple novel roles of luteinizing hormone. Fertil Steril 2001; 76:1097-1100.
83. Rao CV, Lei ZM. Consequences of targeted inactivation of LH receptors. Mol Cell Endocrinol 2002; 187:57-67.
84. Oba Y, Hirai T, Yoshiura Y, Yoshikuni M, Kawauchi H, Nagahama Y. Cloning, functional characterization, and expression of a gonadotropins receptor cDNA in the ovary and testes of Amago salmon (Oncorhynchus rhodurus). Biochem Biophys Res Commun 1999; 263:584-590.
85. Vischer HF, Bogerd J. Cloning and functional characterization of a gonadal luteinizing hormone receptor complementary DNA from the African catfish (Clarias gariepinus). Biol Reprod 2003; 68:262-271.