Mechanisms of serum potentiation of GM-CSF production by human airway smooth muscle cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 287, Issue 5 31-5, 2004, Pages

  Lalor, D J ^a   Truong, B ^a   Henness, S ^a   Blake, A E ^a   Ge, Q ^b   Ammit, A J ^a   Armour, C L ^a   Hughes, J M ^a  

^a UNIVERSITY OF SYDNEY   (Australia)

^b University of Sydney   (Australia)

Author keywords

Granulocyte macrophage colony stimulating factor; NF B; p38 mitogen activated protein kinase; Serum

Indexed keywords

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGENIC AGENT; PLATELET DERIVED GROWTH FACTOR; S6 KINASE; SOMATOMEDIN; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; THROMBIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; ASTHMA; CELL VIABILITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; HUMAN TISSUE; INFLAMMATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; PROTEIN SYNTHESIS; RESPIRATORY SYSTEM; RNA SYNTHESIS; SERUM; SMOOTH MUSCLE FIBER; WESTERN BLOTTING;

ANTIBODIES; BLOOD PROTEINS; CELLS, CULTURED; ENZYME INHIBITORS; EPIDERMAL GROWTH FACTOR; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; HUMANS; INSULIN-LIKE GROWTH FACTOR I; JNK MITOGEN-ACTIVATED PROTEIN KINASES; LUNG; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MITOGENS; MYOCYTES, SMOOTH MUSCLE; NF-KAPPA B; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; TRANSCRIPTION, GENETIC;

EID: 6344235007     PISSN: 10400605     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajplung.00126.2004     Document Type: Article

References (24)

1. Ammit AJ and Panettieri RA Jr. Invited review: the circle of life: cell cycle regulation in airway smooth muscle. J Appl Physiol 91: 1431-1437, 2001.
2. Amrani Y, Ammit AJ, and Panettieri RA Jr. Tumor necrosis factor receptor (TNFR) 1, but not TNFR2, mediates tumor necrosis factor-alpha-induced interleukin-6 and RANTES in human airway smooth muscle cells: role of p38 and p42/44 mitogen-activated protein kinases. Mol Pharmacol 60: 646-655, 2001.
3. Bonacci JV, Harris T, Wilson JW, and Stewart AG. Collagen-induced resistance to glucocorticoid anti-mitogenic actions: a potential explanation of smooth muscle hyperplasia in the asthmatic remodelled airway. Br J Pharmacol 138: 1203-1206, 2003.
4. Chanez P, Vignola M, Stenger R, Vic P, Michel FB, and Bousquet J. Platelet-derived growth factor in asthma. Allergy 50: 878-883, 1995.
5. Chen G, Grotendorst G, Eichholtz T, and Khalil N. GM-CSF increases airway smooth muscle connective tissue expression by inducing TGF-β receptors. Am J Physiol Lung Cell Mol Physiol 284: L548-L556, 2003.
6. Davey RA, Longhurst TJ, Davey MW, Belov L, Harvie RM, Hancox D, and Wheeler H. Drug resistance mechanisms and MRP expression in response to epirubicin treatment in a human leukaemia cell line. Leuk Res 19: 275-282, 1995.
7. Djukanovic R, Wilson JW, Britten KM, Wilson SJ, Walls AF, Roche WR, Howarth PH, and Holgate ST. Quantitation of mast cells and eosinophils in the bronchial mucosa of symptomatic atopic asthmatics and healthy control subjects using immunohistochemistry. Am Rev Respir Dis 142: 863-871, 1990.
8. Hakonarson H, Maskeri N, Carter C, and Grunstein MM. Regulation of TH1- and TH2-type cytokine expression and action in atopic asthmatic sensitized airway smooth muscle. J Clin Invest 103: 1077-1087, 1999.
9. Hallsworth MP, Moir LM, Lai D, and Hirst SJ. Inhibitors of mitogen-activated protein kinases differentially regulate eosinophil-activating cytokine release from human airway smooth muscle. Am J Respir Crit Care Med 164: 688-697, 2001.
10. Hawker KM, Johnson PR, Hughes JM, and Black JL. Interleukin-4 inhibits mitogen-induced proliferation of human airway smooth muscle cells in culture. Am J Physiol Lung Cell Mol Physiol 275: L469-L477, 1998.
11. Heard B and Hossain S. Hyperplasia of bronchial muscle in asthma. J Pathol 110: 319-331, 1973.
12. Johnson PR, Roth M, Tamm M, Hughes M, Ge Q, King G, Burgess JK, and Black JL. Airway smooth muscle cell proliferation is increased in asthma. Am J Respir Crit Care Med 164: 474-477, 2001.
13. Laporte JD, Moore PE, Lahiri T, Schwartzman IN, Panettieri RA Jr, and Shore SA. p38 MAP kinase regulates IL-1β responses in cultured airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 279: L932-L941, 2000.
14. Noveral JP, Bhala A, Hintz RL, Grunstein MM, and Cohen P. Insulin-like growth factor axis in airway smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 267: L761-L765, 1994.
15. Ohba T, McDonald JK, Silver RM, Strange C, LeRoy EC, and Ludwicka A. Scleroderma bronchoalveolar lavage fluid contains thrombin, a mediator of human lung fibroblast proliferation via induction of platelet-derived growth factor alpha-receptor. Am J Respir Cell Mol Biol 10: 405-412, 1994.
16. Oltmanns U, Issa R, Sukkar MB, John M, Chung KF. Role of c-jun N-terminal kinase in the induced release of GM-CSF, RANTES and IL-8 from human airway smooth muscle cells. Br J Pharmacol 139: 1228-1234, 2003.
17. Orsini MJ, Krymskaya VP, Eszterhas AJ, Benovic JL, Panettieri RA Jr, and Penn MB. MAPK superfamily activation in human airway smooth muscle: mitogenesis requires prolonged p42/p44 activation. Am J Physiol Lung Cell Mol Physiol 277: L479-L488, 1999.
18. Scott PH, Belham CM, al-Hafidh J, Chilvers ER, Peacock AJ, Gould GW, and Plevin R. A regulatory role for cAMP in phosphatidylinositol 3-kinase/p70 ribosomal S6 kinase-mediated DNA synthesis in platelet-derived-growth-factor- stimulated bovine airway smooth-muscle cells. Biochem J 318: 965-971, 1996.
19. Shiels IA, Bowler SD, and Taylor SM. Airway smooth muscle proliferation in asthma: the potential of vascular leakage to contribute to pathogenesis. Med Hypotheses 45: 37-40, 1995.
20. Sukkar MB, Hughes JM, Johnson PR, and Armour CL. GM-CSF production from human airway smooth muscle cells is potentiated by human serum. Med Inf (Land) 9: 161-168, 2000.
21. Temkin V and Levi-Schaffer F. Mechanism of tumour necrosis factor alpha mediated eosinophil survival. Cytokine 15: 20-26, 2001.
22. Tomlinson PR, Wilson JW, and Stewart AG. Inhibition by salbutamol of the proliferation of human airway smooth muscle cells grown in culture. Br J Pharmacol 111: 641-647, 1994.
23. Vandermeeren M, Janssens S, Wouters H, Borghmans I, Borgers M, Beyaert R, and Geysen J. Dimethylfumarate is an inhibitor of cytokine-induced nuclear translocation of NF-kappa B1, but not RelA in normal human dermal fibroblast cells. J Invest Dermatol 116: 124-130, 2001.
24. Vanhee D, Gosset P, Wallaert B, Voisin C, and Tonnel AB. Mechanisms of fibrosis in coal workers' pneumoconiosis. Increased production of platelet-derived growth factor, insulin-like growth factor type I, and transforming growth factor beta and relationship to disease severity. Am J Respir Crit Care Med 150: 1049-1055, 1994.