Inhibition of cerebral vasoconstriction by dantrolene and nimodipine

Neurocritical Care

Volumn 10, Issue 1, 2009, Pages 93-102

  Salomone, Salvatore ^a   Soydan, Guray ^a   Moskowitz, Michael A ^a   Sims, John Randall ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Basilar artery; Calcium; Dantrolene; Endothelin 1; Nimodipine; Phenylephrine; Ryanodine receptor; Sarco endoplasmic reticulum; Serotonin; Vasospasm

Indexed keywords

CALCIUM; DANTROLENE; ENDOTHELIN 1; NIMODIPINE; PHENYLEPHRINE; RYANODINE RECEPTOR 3; SEROTONIN; CENTRAL MUSCLE RELAXANT; RYANODINE RECEPTOR; VASODILATOR AGENT;

ANIMAL TISSUE; ARTICLE; BASILAR ARTERY; BRAIN ARTERY; BRAIN VASOSPASM; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; EX VIVO STUDY; FEMORAL ARTERY; IMMUNOFLUORESCENCE; ISOLATED ARTERY; MALE; MYOGRAPHY; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TISSUE CULTURE TECHNIQUE; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION;

ANIMALS; BASILAR ARTERY; DANTROLENE; FEMORAL ARTERY; MALE; MUSCLE RELAXANTS, CENTRAL; MUSCLE, SMOOTH, VASCULAR; NIMODIPINE; RATS; RATS, SPRAGUE-DAWLEY; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; TISSUE CULTURE TECHNIQUES; VASOCONSTRICTION; VASODILATOR AGENTS;

EID: 63249126018     PISSN: 15416933     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12028-008-9153-0     Document Type: Article

References (57)

1. T Krause MU Gerbershagen M Fiege R Weisshorn F Wappler 2004 Dantrolene-a review of its pharmacology, therapeutic use and new developments Anaesthesia 59 4 364 73 10.1111/j.1365-2044.2004.03658.x 10.1111/j.1365-2044.2004.03658.x 1:CAS:528:DC%2BD2cXktVOhsrY%3D 15023108 (Pubitemid 38489297)
2. M Endo 2006 Calcium ion as a second messenger with special reference to excitation-contraction coupling J Pharmacol Sci 100 5 519 24 10.1254/jphs.CPJ06004X 10.1254/jphs.CPJ06004X 1:CAS:528:DC%2BD28XmvVajsrY%3D 16702757 (Pubitemid 44609541)
3. F Zhao P Li SR Chen CF Louis BR Fruen 2001 Dantrolene inhibition of ryanodine receptor Ca2+ release channels. Molecular mechanism and isoform selectivity J Biol Chem 276 17 13810 6 1:CAS:528:DC%2BD3MXjt12kurk%3D 11278295
4. NW Dorsch 1995 Cerebral arterial spasm-a clinical review Br J Neurosurg 9 3 403 12 10.1080/02688699550041403 10.1080/02688699550041403 1:STN:280:BymD3s7mt1A%3D 7546361
5. E Tani T Matsumoto 2004 Continuous elevation of intracellular Ca2+ is essential for the development of cerebral vasospasm Curr Vasc Pharmacol 2 1 13 21 10.2174/1570161043476492 10.2174/1570161043476492 1:CAS:528:DC%2BD2cXpvVeg 15320829 (Pubitemid 38855011)
6. SS Beg JA Hansen-Schwartz PJ Vikman CB Xu LI Edvinsson 2007 Protein kinase C inhibition prevents upregulation of vascular ET(B) and 5-HT(1B) receptors and reverses cerebral blood flow reduction after subarachnoid haemorrhage in rats J Cereb Blood Flow Metab 27 1 21 32 10.1038/sj.jcbfm.9600313 10.1038/sj.jcbfm.9600313 1:CAS:528:DC%2BD2sXptlekuw%3D%3D 16736053 (Pubitemid 46006581)
7. S Ansar NA Svendgaard L Edvinsson 2007 Neurokinin-1 receptor antagonism in a rat model of subarachnoid hemorrhage: prevention of upregulation of contractile ETB and 5-HT1B receptors and cerebral blood flow reduction J Neurosurg 106 5 881 6 10.3171/jns.2007.106.5.881 10.3171/jns.2007.106.5.881 1:CAS:528:DC%2BD2sXlsF2msbc%3D 17542534 (Pubitemid 46698675)
8. C Alafaci I Jansen MA Arbab Y Shiokawa NA Svendgaard L Edvinsson 1990 Enhanced vasoconstrictor effect of endothelin in cerebral arteries from rats with subarachnoid haemorrhage Acta Physiol Scand 138 3 317 9 10.1111/j.1748-1716.1990.tb08852.x 1:CAS:528:DyaK3cXhslejsbw%3D 2183539
9. Dorhout Mees SM, Rinkel GJ, Feigin VL, et al. Calcium antagonists for aneurysmal subarachnoid haemorrhage. Cochrane Database Syst Rev. 2007;(3):CD000277.
10. T Godfraind R Miller M Wibo 1986 Calcium antagonism and calcium entry blockade Pharmacol Rev 38 4 321 416 1:CAS:528:DyaL2sXpsFersA%3D%3D 2432624
11. AY Zhang PL Li 2006 Vascular physiology of a Ca2+ mobilizing second messenger - cyclic ADP-ribose J Cell Mol Med 10 2 407 22 10.1111/j.1582-4934. 2006.tb00408.x 10.1111/j.1582-4934.2006.tb00408.x 1:CAS:528:DC%2BD2sXlvFCltbo%3D 16796808 (Pubitemid 44870188)
12. P Pacaud G Loirand 1995 Release of Ca2+ by noradrenaline and ATP from the same Ca2+ store sensitive to both InsP3 and Ca2+ in rat portal vein myocytes J Physiol 484 Pt 3 549 55 1:CAS:528:DyaK2MXls1Kqu7k%3D 7623275
13. T Kamishima JG McCarron 1997 Regulation of the cytosolic Ca2+ concentration by Ca2+ stores in single smooth muscle cells from rat cerebral arteries J Physiol 501 Pt 3 497 508 10.1111/j.1469-7793.1997.497bm.x 10.1111/j.1469-7793.1997.497bm.x 1:CAS:528:DyaK2sXkt1eqsL0%3D 9218210 (Pubitemid 27300004)
14. M Asano M Kuwako Y Nomura, et al. 1996 Possible mechanism of the potent vasoconstrictor responses to ryanodine in dog cerebral arteries Eur J Pharmacol 311 1 53 60 10.1016/0014-2999(96)00408-6 10.1016/0014-2999(96)00408-6 1:CAS:528:DyaK28XlsFWksro%3D 8884236 (Pubitemid 26298499)
15. R Loch Macdonald 2006 Management of cerebral vasospasm Neurosurg Rev 29 3 179 93 10.1007/s10143-005-0013-5 10.1007/s10143-005-0013-5 1:STN:280: DC%2BD28zmtFalug%3D%3D 16501930
16. Muehlschlegel S, Sims JR. Dantrolene: mechanisms of neuroprotection and possible clinical applications in the neurointensive care unit. Neurocrit Care. 2008. doi: 10.1007/s12028-008-9133-4.
17. MJ Mulvany W Halpern 1977 Contractile properties of small arterial resistance vessels in spontaneously hypertensive and normotensive rats Circ Res 41 1 19 26 1:STN:280:CSiC1czovFQ%3D 862138
18. KD Ramsch G Ahr D Tettenborn LM Auer 1985 Overview on pharmacokinetics of nimodipine in healthy volunteers and in patients with subarachnoid hemorrhage Neurochirurgia (Stuttg) 28 Suppl 1 74 8
19. L Schilling H Vatter K Mursch H Ehrenreich P Schmiedek 2000 Characterization of the contractile and relaxant action of the endothelin-1 precursor, big endothelin-1, in the isolated rat basilar artery Peptides 21 1 91 9 10.1016/S0196-9781(99)00179-5 10.1016/S0196-9781(99)00179-5 1:CAS:528:DC%2BD3cXhsVantbs%3D 10704724 (Pubitemid 30126047)
20. S Salomone N Morel T Godfraind 1997 Role of nitric oxide in the contractile response to 5-hydroxytryptamine of the basilar artery from Wistar Kyoto and stroke-prone rats Br J Pharmacol 121 6 1051 8 10.1038/sj.bjp.0701227 10.1038/sj.bjp.0701227 1:CAS:528:DyaK2sXkvFeqsrk%3D 9249238 (Pubitemid 27303571)
21. Y Nishimura 1996 Characterization of 5-hydroxytryptamine receptors mediating contractions in basilar arteries from stroke-prone spontaneously hypertensive rats Br J Pharmacol 117 6 1325 33 1:CAS:528:DyaK28XitVemsrY%3D 8882632
22. A Jackowski A Crockard G Burnstock J Lincoln 1989 Alterations in serotonin and neuropeptide Y content of cerebrovascular sympathetic nerves following experimental subarachnoid hemorrhage J Cereb Blood Flow Metab 9 3 271 9 1:CAS:528:DyaL1MXksFGitb8%3D 2497110
23. L Cambj-Sapunar M Yu DR Harder RJ Roman 2003 Contribution of 5-hydroxytryptamine1B receptors and 20-hydroxyeiscosatetraenoic acid to fall in cerebral blood flow after subarachnoid hemorrhage Stroke 34 5 1269 75 10.1161/01.STR.0000065829.45234.69 10.1161/01.STR.0000065829.45234.69 12677022 (Pubitemid 36547527)
24. JY Chang JE Hardebo C Owman 1988 Differential vasomotor action of noradrenaline, serotonin, and histamine in isolated basilar artery from rat and guinea-pig Acta Physiol Scand 132 1 91 102 10.1111/j.1748-1716.1988.tb08302.x 1:CAS:528:DyaL1cXovVCiuw%3D%3D 2906211
25. T Kitazono FM Faraci DD Heistad 1993 Effect of norepinephrine on rat basilar artery in vivo Am J Physiol 264 1 Pt 2 H178 82 1:CAS:528: DyaK3sXhtFOgtL0%3D 8430844
26. AJ Kaumann FO Levy 2006 5-Hydroxytryptamine receptors in the human cardiovascular system Pharmacol Ther 111 3 674 706 10.1016/j.pharmthera.2005.12. 004 10.1016/j.pharmthera.2005.12.004 1:CAS:528:DC%2BD28Xns1Sks70%3D 16960982 (Pubitemid 44118434)
27. CM Villalon D Centurion 2007 Cardiovascular responses produced by 5-hydroxytriptamine: a pharmacological update on the receptors/mechanisms involved and therapeutic implications Naunyn Schmiedebergs Arch Pharmacol 376 1-2 45 63 10.1007/s00210-007-0179-1 10.1007/s00210-007-0179-1 1:CAS:528:DC%2BD2sXht1ygt7zK 17703282
28. AA Parsons ET Whalley 1989 Evidence for the presence of 5-HT1-like receptors in rabbit isolated basilar arteries Eur J Pharmacol 174 2-3 189 96 10.1016/0014-2999(89)90311-7 10.1016/0014-2999(89)90311-7 1:CAS:528: DyaK3cXpt1ertw%3D%3D 2560978 (Pubitemid 20029398)
29. AA Parsons ET Whalley W Feniuk HE Connor PP Humphrey 1989 5-HT1-like receptors mediate 5-hydroxytryptamine-induced contraction of human isolated basilar artery Br J Pharmacol 96 2 434 40 1:CAS:528:DyaL1MXhtVyrsLo%3D 2538194
30. YM Bae A Kim J Kim, et al. 2006 Serotonin depolarizes the membrane potential in rat mesenteric artery myocytes by decreasing voltage-gated K+ currents Biochem Biophys Res Commun 347 2 468 76 10.1016/j.bbrc.2006.06.116 10.1016/j.bbrc.2006.06.116 1:CAS:528:DC%2BD28XntFWktLg%3D 16828462 (Pubitemid 44041439)
31. YM Bae A Kim YJ Lee, et al. 2007 Enhancement of receptor-operated cation current and TRPC6 expression in arterial smooth muscle cells of deoxycorticosterone acetate-salt hypertensive rats J Hypertens 25 4 809 17 10.1097/HJH.0b013e3280148312 10.1097/HJH.0b013e3280148312 1:CAS:528: DC%2BD2sXislSrsbs%3D 17351373 (Pubitemid 46398876)
32. D MacMillan S Chalmers TC Muir JG McCarron 2005 IP3-mediated Ca2+ increases do not involve the ryanodine receptor, but ryanodine receptor antagonists reduce IP3-mediated Ca2+ increases in guinea-pig colonic smooth muscle cells J Physiol 569 Pt 2 533 44 10.1113/jphysiol.2005.096529 10.1113/jphysiol.2005.096529 1:CAS:528:DC%2BD28XhsVansg%3D%3D 16195318 (Pubitemid 41830120)
33. S Sakurada H Okamoto N Takuwa N Sugimoto Y Takuwa 2001 Rho activation in excitatory agonist-stimulated vascular smooth muscle Am J Physiol Cell Physiol 281 2 C571 8 1:CAS:528:DC%2BD3MXlvFymurc%3D 11443056
34. Y Kawanabe SM Nauli 2005 Involvement of extracellular Ca2+ influx through voltage-independent Ca2+ channels in endothelin-1 function Cell Signal 17 8 911 6 10.1016/j.cellsig.2005.01.001 10.1016/j.cellsig.2005.01.001 1:CAS:528:DC%2BD2MXkt1Ohu74%3D 15894164 (Pubitemid 40719112)
35. Y Kawanabe T Masaki N Hashimoto 2006 Involvement of phospholipase C in endothelin 1-induced stimulation of Ca++ channels and basilar artery contraction in rabbits J Neurosurg 105 2 288 93 10.3171/jns.2006.105.2.288 10.3171/jns.2006.105.2.288 1:CAS:528:DC%2BD28XovFyrt7Y%3D 17219836
36. AM Evans HJ Cobban GFET Nixon 1999 (A) receptors are the primary mediators of myofilament calcium sensitization induced by ET-1 in rat pulmonary artery smooth muscle: a tyrosine kinase independent pathway Br J Pharmacol 127 1 153 60 10.1038/sj.bjp.0702548 10.1038/sj.bjp.0702548 1:CAS:528: DyaK1MXjtVGltrk%3D 10369468 (Pubitemid 29213244)
37. AP Somlyo AV Somlyo 1998 From pharmacomechanical coupling to G-proteins and myosin phosphatase Acta Physiol Scand 164 4 437 48 10.1046/j.1365-201X.1998. 00454.x 10.1046/j.1365-201X.1998.00454.x 1:CAS:528:DyaK1MXltFCitA%3D%3D 9887967 (Pubitemid 29015663)
38. L Miao Y Dai J Zhang 2002 Mechanism of RhoA/Rho kinase activation in endothelin-1-induced contraction in rabbit basilar artery Am J Physiol Heart Circ Physiol 283 3 H983 9 1:CAS:528:DC%2BD38XntFOgtb8%3D 12181127
39. EQ Scherer M Herzog P Wangemann 2002 Endothelin-1-induced vasospasms of spiral modiolar artery are mediated by rho-kinase-induced Ca(2+) sensitization of contractile apparatus and reversed by calcitonin gene-related peptide Stroke 33 12 2965 71 10.1161/01.STR.0000043673.22993.FD 10.1161/01.STR.0000043673. 22993.FD 1:CAS:528:DC%2BD38XptVSht7k%3D 12468798 (Pubitemid 35462873)
40. GC Churchill A Galione 2001 NAADP induces Ca2+ oscillations via a two-pool mechanism by priming IP3- and cADPR-sensitive Ca2+ stores EMBO J 20 11 2666 71 10.1093/emboj/20.11.2666 10.1093/emboj/20.11.2666 1:CAS:528: DC%2BD3MXksFGrsLg%3D 11387201 (Pubitemid 32938551)
41. H Higashida 1997 ADP-ribosyl cyclase coupled with receptors via G proteins FEBS Lett 418 3 355 6 10.1016/S0014-5793(97)01410-5 10.1016/S0014-5793(97)01410-5 1:CAS:528:DyaK2sXnsVyjsLg%3D 9428744 (Pubitemid 27515956)
42. HL Wilson M Dipp JM Thomas C Lad A Galione AM Evans 2001 Adp-ribosyl cyclase and cyclic ADP-ribose hydrolase act as a redox sensor. a primary role for cyclic ADP-ribose in hypoxic pulmonary vasoconstriction J Biol Chem 276 14 11180 8 10.1074/jbc.M004849200 10.1074/jbc.M004849200 1:CAS:528: DC%2BD3MXjvFGjsL8%3D 11116136 (Pubitemid 38089302)
43. T Godfraind 2006 Calcium-channel modulators for cardiovascular disease Expert Opin Emerg Drugs 11 1 49 73 10.1517/14728214.11.1.49 10.1517/14728214.11. 1.49 1:CAS:528:DC%2BD28XhvVKgtLs%3D 16503826
44. R Laporte A Hui I Laher 2004 Pharmacological modulation of sarcoplasmic reticulum function in smooth muscle Pharmacol Rev 56 4 439 513 10.1124/pr.56.4.1 10.1124/pr.56.4.1 1:CAS:528:DC%2BD2MXhtFWlt7o%3D 15602008 (Pubitemid 39658461)
45. H Takeshima T Ikemoto M Nishi, et al. 1996 Generation and characterization of mutant mice lacking ryanodine receptor type 3 J Biol Chem 271 33 19649 52 10.1074/jbc.271.33.19649 10.1074/jbc.271.33.19649 1:CAS:528:DyaK28XltVKkur8%3D 8702664 (Pubitemid 26281695)
46. M Lohn W Jessner M Furstenau, et al. 2001 Regulation of calcium sparks and spontaneous transient outward currents by RyR3 in arterial vascular smooth muscle cells Circ Res 89 11 1051 7 10.1161/hh2301.100250 10.1161/hh2301.100250 1:CAS:528:DC%2BD3MXovFGhs7c%3D 11717163
47. HJ Knot NB Standen MT Nelson 1998 Ryanodine receptors regulate arterial diameter and wall [Ca2+] in cerebral arteries of rat via Ca2+-dependent K+ channels J Physiol 508 Pt 1 211 21 1:CAS:528:DyaK1cXis1CqsLY%3D 9490841
48. GJ Perez AD Bonev JB Patlak MT Nelson 1999 Functional coupling of ryanodine receptors to KCa channels in smooth muscle cells from rat cerebral arteries J Gen Physiol 113 2 229 38 10.1085/jgp.113.2.229 10.1085/jgp.113.2.229 1:CAS:528:DyaK1MXht1yhtr4%3D 9925821 (Pubitemid 29219796)
49. GC Amberg AD Bonev CF Rossow MT Nelson LF Santana 2003 Modulation of the molecular composition of large conductance, Ca(2+) activated K(+) channels in vascular smooth muscle during hypertension J Clin Invest 112 5 717 24 1:CAS:528:DC%2BD3sXntlSiurY%3D 12952920
50. ML Collier G Ji Y Wang MI Kotlikoff 2000 Calcium-induced calcium release in smooth muscle: loose coupling between the action potential and calcium release J Gen Physiol 115 5 653 62 10.1085/jgp.115.5.653 10.1085/jgp.115.5.653 1:CAS:528:DC%2BD3cXjtl2gsrg%3D 10779321 (Pubitemid 30249979)
51. J Hansen-Schwartz S Ansar L Edvinsson 2008 Cerebral vasoconstriction after subarachnoid hemorrhage-role of changes in vascular receptor phenotype Front Biosci 13 2160 4 10.2741/2831 10.2741/2831 1:CAS:528:DC%2BD1cXhs1CgtLY%3D 17981699 (Pubitemid 351589242)
52. AD Mendelow TA McCalden J Hattingh A Coull C Rosendorff BH Eidelman 1981 Cerebrovascular reactivity and metabolism after subarachnoid hemorrhage in baboons Stroke 12 1 58 65 1:CAS:528:DyaL3MXotFOjsQ%3D%3D 6784284
53. C Sahlin C Owman JY Chang T Delgado LG Salford NA Svendgaard 1990 Changes in contractile response and effect of a calcium antagonist, nimodipine, in isolated intracranial arteries of baboon following experimental subarachnoid hemorrhage Brain Res Bull 24 3 355 61 10.1016/0361-9230(90)90089-I 10.1016/0361-9230(90)90089-I 1:CAS:528:DyaK3cXitFSktb4%3D 2337815 (Pubitemid 20119425)
54. LH Calabrese DW Dodick TJ Schwedt AB Singhal 2007 Narrative review: reversible cerebral vasoconstriction syndromes Ann Intern Med 146 1 34 44 17200220
55. GW Weyer CP Nolan RL Macdonald 2006 Evidence-based cerebral vasospasm management Neurosurg Focus 21 3 E8 10.3171/foc.2006.21.3.8 10.3171/foc.2006.21. 3.8 17029347
56. DW Dodick 2003 Reversible segmental cerebral vasoconstriction (Call-Fleming syndrome): the role of calcium antagonists Cephalalgia 23 3 163 5 10.1046/j.1468-2982.2003.00506.x 10.1046/j.1468-2982.2003.00506.x 1:STN:280:DC%2BD3s7osVWltw%3D%3D 12662181 (Pubitemid 36461383)
57. Muehlschlegel S, Rordorf G, Bodock M, Sims JR. Dantrolene mediates vasorelaxation in cerebral vasoconstriction: a case series. Neurocrit Care. 2008. doi: 10.1007/s12028-008-9132-5.