Preferential brain homing following intranasal administration of trypanosoma cruzi

Infection and Immunity

Volumn 77, Issue 4, 2009, Pages 1349-1356

  Caradonna, Kacey ^a   Pereiraperrin, Mercio ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DYE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BASAL GANGLION; BRAIN; BRAIN INFECTION; CHAGAS DISEASE; CONTROLLED STUDY; DISEASE COURSE; FEMALE; INTESTINE INNERVATION; LOCOMOTION; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; NOSE CAVITY; NOSE MUCOSA; PARASITEMIA; PRIORITY JOURNAL; SURVIVAL RATE; TRYPANOSOMA CRUZI; ANIMAL; BAGG ALBINO MOUSE; C57BL MOUSE; DISEASE MODEL; EVALUATION; GENETICS; HUMAN; IMMUNOHISTOCHEMISTRY; INTRANASAL DRUG ADMINISTRATION; ISOLATION AND PURIFICATION; METHODOLOGY; MORTALITY; PARASITOLOGY; PATHOGENICITY; PATHOLOGY; POLYMERASE CHAIN REACTION;

ADMINISTRATION, INTRANASAL; ANIMALS; BASAL GANGLIA; BRAIN; CHAGAS DISEASE; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NASAL CAVITY; PARASITEMIA; POLYMERASE CHAIN REACTION; TRYPANOSOMA CRUZI;

EID: 63149194222     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.01434-08     Document Type: Article

References (45)

1. Adad, S. J., C. G. Cancado, R. M. Etchebehere, V. P. Teixeira, U. A. Gomes, E. Chapadeiro, and E. R. Lopes. 2001. Neuron count reevaluation in the myenteric plexus of chagasic megacolon after morphometric neuron analysis. Virchows Arch. 438:254-258.
2. Akpan, N., K. Caradonna, M. V. Chuenkova, and M. PereiraPerrin. 2008. Chagas' disease parasite-derived neurotrophic factor activates cholinergic gene expression in neuronal PC12 cells. Brain Res. 1217:195-202.
3. Arantes, R. M., H. H. Marche, M. T. Bahia, F. Q. Cunha, M. A. Rossi, and J. S. Silva. 2004. Interferon-gamma-induced nitric oxide causes intrinsic intestinal denervation in Trypanosoma crwzi-infected mice. Am. J. Pathol. 164:1361-1368.
4. Beal, M. F., E. Brouillet, B. G. Jenkins, R. J. Ferrante, N. W. Kowall, J. M. Miller, E. Storey, R. Srivastava, B. R. Rosen, and B. T. Hyman. 1993. Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J. Neurosci. 13:4181-4192.
5. Blum, J. A., M. J. Zellweger, C. Burri, and C. Hatz. 2008. Cardiac involvement in African and American trypanosomiasis. Lancet Infect. Dis. 8:631-641.
6. Brouillet, E., F. Conde, M. F. Beal, and P. Hantraye. 1999. Replicating Huntington's disease phenotype in experimental animals. Prog. Neurobiol. 59:427-168.
7. Chimelli, L., and F. Scaravilli. 1997. Trypanosomiasis. Brain Pathol. 7:599-611.
8. Chuenkova, M., and M. E. Pereira. 1995. Trypanosoma cruzi trans-sialidase: enhancement of virulence in a murine model of Chagas' disease. J. Exp. Med. 181:1693-1703.
9. Chuenkova, M. V., and M. PereiraPerrin. 2004. Chagas' disease parasite promotes neuron survival and differentiation through TrkA nerve growth factor receptor. J. Neurochem. 91:385-394.
10. Cowan, C. M., and L. A. Raymond. 2006. Selective neuronal degeneration in Huntington's disease. Curr. Top. Dev. Biol. 75:25-71.
11. Cummings, K. L., and R. L. Tarleton. 2003. Rapid quantitation of Trypano- soma cruzi in host tissue by real-time PCR. Mol. Biochem. Parasitol. 129:53-59.
12. Da Mata, J. R., M. R. Camargos, E. Chiari, and C. R. Machado. 2000. Trypanosoma cruzi infection and the rat central nervous system: proliferation of parasites in astrocytes and the brain reaction to parasitism. Brain Res. Bull. 53:153-162.
13. da Silveira, A. B., M. A. Freitas, E. C. de Oliveira, S. G. Neto, A. O. Luquetti, J. B. Furness, R. Correa-Oliveira, and D. d'Avila Reis. 2008. Neuronal plasticity of the enteric nervous system is correlated with chagasic megacolon development. Parasitology 135:1337-1342.
14. Del Castillo, M., G. Mendoza, J. Oviedo, R. P. Perez Bianco, A. E. Anselmo, and M. Silva. 1990. AIDS and Chagas' disease with central nervous system tumor-like lesion. Am. J. Med. 88:693-694.
15. de Melo-Jorge, M., and M. PereiraPerrin. 2007. The Chagas' disease parasite Trypanosoma cruzi exploits nerve growth factor receptor TrkA to infect mammalian hosts. Cell Host Microbe 1:251-261.
16. Fernagut, P. O., E. Diguet, N. Stefanova, M. Biran, G. K. Wenning, P. Canioni, B. Bioulac, and F. Tison. 2002. Subacute systemic 3-nitropropionic acid intoxication induces a distinct motor disorder in adult C57BL/6 mice: behavioural and histopathological characterisation. Neuroscience 114:1005-1017.
17. Genovese, O., C. Ballario, R. Storino, E. Segura, and R. E. Sica. 1996. Clinical manifestations of peripheral nervous system involvement in human chronic Chagas disease. Arq. Neuropsiquiatr. 54:190-196.
18. Giddings, O. K., C. S. Eickhoff, T. J. Smith, L. A. Bryant, and D. F. Hoft. 2006. Anatomical route of invasion and protective mucosal immunity in Trypanosoma cruzi conjunctival infection. Infect. Immun. 74:5549-5560.
19. Gonzalez Cappa, S. M., O. P. Sanz, L. A. Muller, H. A. Molina, J. Fernandez, M. T. Rimoldi, and R. E. Sica. 1987. Peripheral nervous system damage in experimental chronic Chagas' disease. Am. J. Trop. Med. Hyg. 36:41-45.
20. Hoff, R., R. S. Teixeira, J. S. Carvalho, and K. E. Mott. 1978. Trypanosoma cruzi in the cerebrospinal fluid during the acute stage of Chagas' disease. N. Engl. J. Med. 298:604-606.
21. Hunter, C. A., T. Slifer, and F. Araujo. 1996. Interleukin-12-mediated resistance to Trypanosoma cruzi is dependent on tumor necrosis factor alpha and gamma interferon. Infect. Immun. 64:2381-2386.
22. Kennedy, P. G. 2008. The continuing problem of human African trypanoso- miasis (sleeping sickness). Ann. Neurol. 64:116-126.
23. Koberle, F. 1968. Chagas' disease and Chagas' syndromes: the pathology of American trypanosomiasis. Adv. Parasitol. 6:63-116.
24. Kohl, S., L. K. Pickering, L. S. Frankel, and R. G. Yaeger. 1982. Reactivation of Chagas' disease during therapy of acute lymphocytic leukemia. Cancer 50:827-828.
25. Kress, Y., B. R. Bloom, M. Wittner, A. Rowen, and H. Tanowitz. 1975. Resistance of Trypanosoma cruzi to killing by macrophages. Nature 257:394-396.
26. Le, W., S. Chen, and J. Jankovic. 2009. Etiopathogenesis of Parkinson disease: a new beginning? Neuroscientist 15:28-35.
27. Leiguarda, R., A. Roncoroni, A. L. Taratuto, L. Jost, M. Berthier, M. Nogues, and H. Freilij. 1990. Acute CNS infection by Trypanosoma cruzi (Chagas' disease) in immunosuppressed patients. Neurology 40:850-851.
28. Lu, B., and M. PereiraPerrin. 2008. A novel immunoprecipitation strategy identifies a unique functional mimic of the glial cell line-derived neurotro- phic factor family ligands in the pathogen Trypanosoma cruzi. Infect. Immun. 76:3530-3538.
29. Ludolph, A. C., F. He, P. S. Spencer, J. Hammerstad, and M. Sabri. 1991. 3-Nitropropionic acid-exogenous animal neurotoxin and possible human striatal toxin. Can. J. Neurol. Sci. 18:492-498.
30. Meneghelli, U. G. 1985. Chagas' disease: a model of denervation in the study of digestive tract motility. Braz. J. Med. Biol. Res. 18:255-264.
31. Michailowsky, V., N. M. Silva, C. D. Rocha, L. Q. Vieira, J. Lannes-Vieira, and R. T. Gazzinelli. 2001. Pivotal role of interleukin-12 and interferon- gamma axis in controlling tissue parasitism and inflammation in the heart and central nervous system during Trypanosoma cruzi infection. Am. J. Pathol. 159:1723-1733.
32. Olitsky, P. K., and H. R. Cox. 1934. Temporary prevention by chemical means of intranasal infection of mice with equine encephalomyelitis virus. Science 80:566-567.
33. Prioli, R. P., J. S. Mejia, and M. E. Pereira. 1990. Monoclonal antibodies against Trypanosoma cruzi neuraminidase reveal enzyme polymorphism, recognize a subset of trypomastigotes, and enhance infection in vitro. J. Immunol. 144:4384-4391.
34. Rosemberg, S., C. J. Chaves, M. L. Higuchi, M. B. Lopes, L. H. Castro, and L. R. Machado. 1992. Fatal meningoencephalitis caused by reactivation of Trypanosoma cruzi infection in a patient with AIDS. Neurology 42:640-642.
35. Schmued, L. C., C. C. Stowers, A. C. Scallet, and L. Xu. 2005. Fluoro-Jade C results in ultra high resolution and contrast labeling of degenerating neurons. Brain Res. 1035:24-31.
36. Silva, A. A., E. Roffe, A. P. Marino, P. V. dos Santos, T. Quirico-Santos, C. N. Paiva, and J. Lannes-Vieira. 1999. Chagas' disease encephalitis: intense CD8+ lymphocytic infiltrate is restricted to the acute phase, but is not related to the presence of Trypanosoma cruzi antigens. Clin. Immunol. 92:56-66.
37. Silva, A. A., E. Roffe, H. Santiago, A. P. Marino, K. Kroll-Palhares, M. M. Teixeira, R. T. Gazzinelli, and J. Lannes-Vieira. 2007. Trypanosoma cruzi- triggered meningoencephalitis is a CCR1/CCR5-independent inflammatory process. J. Neuroimmunol. 184:156-163.
38. Tanowitz, H. B., L. V. Kirchhoff, D. Simon, S. A. Morris, L. M. Weiss, and M. Wittner. 1992. Chagas' disease. Clin. Microbiol. Rev. 5:400-419.
39. Thorne, R. G., G. J. Pronk, V. Padmanabhan, and W. H. Frey II. 2004. Delivery of insulin-like growth factor-I to the rat brain and spinal cord along olfactory and trigeminal pathways following intranasal administration. Neu- roscience 127:481-496.
40. Townsend, G. C., and W. M. Scheld. 1998. Infections of the central nervous system. Adv. Intern. Med. 43:403-447.
41. Trischmann, T., H. Tanowitz, M. Wittner, and B. Bloom. 1978. Trypanosoma cruzi: role of the immune response in the natural resistance of inbred strains of mice. Exp. Parasitol. 45:160-168.
42. Vaidian, A. K., L. M. Weiss, and H. B. Tanowitz. 2004. Chagas' disease and AIDS. Kinetoplastid Biol. Dis. 3:2.
43. van Ginkel, F. W., J. R. McGhee, J. M. Watt, A. Campos-Torres, L. A. Parish, and D. E. Briles. 2003. Pneumococcal carriage results inganglioside- mediated olfactory tissue infection. Proc. Natl. Acad. Sci. USA 100:14363-14367.
44. Wiesinger, D. 1956. Importance of environmental factors for the blood sucking activity of Triatoma infestans. Acta Trop. 13:97-141.
45. Zeledon, R. 1975. Effects of triatomine behavior on trypanosoma transmission. PAHO Sci. Publ. 318:326-329.