Adjustment of L-T4 substitutive therapy in pregnant women with subclinical, overt or post-ablative hypothyroidism

Clinical Endocrinology

Volumn 70, Issue 5, 2009, Pages 798-802

  Verga, Uberta ^b   Bergamaschi, Silvia ^b   Cortelazzi, Donatella ^b   Ronzoni, Stefania ^b   Marconi, Anna Maria ^b   Beck Peccoz, Paolo ^a,b  

^a Endocrinology and Diabetology Unit   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

LEVOTHYROXINE; THYROTROPIN; THYROXINE;

ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; FEMALE; GESTATION PERIOD; HUMAN; HYPOTHYROIDISM; MAJOR CLINICAL STUDY; PREGNANCY; PRIORITY JOURNAL; ADULT; BLOOD; PREGNANCY COMPLICATION; RETROSPECTIVE STUDY;

ADULT; FEMALE; HUMANS; HYPOTHYROIDISM; PREGNANCY; PREGNANCY COMPLICATIONS; PREGNANCY TRIMESTERS; RETROSPECTIVE STUDIES; THYROTROPIN; THYROXINE;

EID: 63149146127     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/j.1365-2265.2008.03398.x     Document Type: Article

References (26)

1. Stagnaro-Green, A., Roman, S.H., Cobin, R.H. et al. (1990) Detection of at-risk pregnancy by means of highly sensitive assays for thyroid autoantibodies. Journal of the American Medical Association, 264, 1422 1425.
2. Glinoer, D. (1997) The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology to pathology. Endocrine Review, 18, 404 433.
3. Lazarus, J.H. Kokandi, A. (2000) Thyroid disease in relation to pregnancy: a decade of change. Clinical Endocrinology, 53, 265 278.
4. Chopra, I.J. Barber, K. (2003) Treatment of primary hypothyroidism during pregnancy: is there an increase in thyroxine dose requirement in pregnancy? Metabolism, 52, 122 128.
5. Gharib, H., Tuttle, R.M., Baskin, H.J. et al. (2005) Subclinical thyroid dysfunction: a joint statement on management from the American Association of Clinical Endocrinologists, the American Thyroid Association, and The Endocrine Society. Journal of Clinical Endocrinology and Metabolism, 90, 581 585.
6. Becks, G.P. Burrow, G.N. (1991) Thyroid disease and pregnancy. Medical Clinics of North America, 75, 121 150.
7. Kaplan, M.M. (1992) Monitoring thyroxine treatment during pregnancy. Thyroid, 2, 147 152.
8. Burrow, G.N., Fisher, D.A. Larsen, P.R. (1994) Maternal and fetal thyroid function. New England Journal of Medicine, 331, 1072 1078.
9. Haddow, J.E., Palomaki, G.E., Allan, W.C. et al. (1999) Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. New England Journal of Medicine, 341, 549 555.
10. Glinoer, D. (2000) Potential repercussions for the progeny of maternal hypothyroxinemia during pregnancy. Thyroid, 10, 59 62.
11. Abalovich, M., Gutierrez, S., Alcaraz, G. et al. (2002) Overt and subclinical hypothyroidism complicating pregnancy. Thyroid, 12, 63 68.
12. Pop, V.J., Brouwers, E.P., Vader, H.L. et al. (2003) Maternal hypothyroxinaemia during early pregnancy and subsequent child development: a 3-year follow-up study. Clinical Endocrinology, 59, 282 288.
13. LaFranchi, S.H., Haddow, J.E. Hollowell, J.G. (2005) Is thyroid inadequacy during gestation a risk factor for adverse pregnancy and developmental outcomes? Thyroid, 15, 60 71.
14. Surks, M.I., Ortiz, E., Daniels, G.H. et al. (2004) Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. Journal of the American Medical Association, 291, 228 238.
15. Mandel, S.J. (2004) Hypothyroidism and chronic autoimmune thyroiditis in the pregnant state: maternal aspects. Best Practice and Research. Clinical Endocrinology and Metabolism, 18, 213 224.
16. Col, N.F., Surks, M.I. Daniels, G.H. (2004) Subclinical thyroid disease: clinical applications. Journal of the American Medical Association, 291, 239 243.
17. Negro, R., Formoso, G., Mangieri, T. et al. (2006) Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. Journal of Clinical Endocrinology and Metabolism, 91, 2587 2591.
18. Casey, B.M., Dashe, J.S., Wells, C.E. et al. (2005) Subclinical hypothyroidism and pregnancy outcomes. Obstetrics and Gynecology, 105, 239 245.
19. Smallridge, R.C., Glinoer, D., Hollowell, J.G. et al. (2005) Thyroid function inside and outside of pregnancy: what do we know and what don't we know? Thyroid, 15, 54 59.
20. Mandel, S.J., Spencer, C.A. Hollowell, J.G. (2005) Are detection and treatment of thyroid insufficiency in pregnancy feasible? Thyroid, 15, 44 53.
21. Lazarus, J.H. (2005) Thyroid disorders associated with pregnancy: etiology, diagnosis, and management. Treatments in Endocrinology, 4, 31 41.
22. Dickey, R.A., Wartofsky, L. Feld, S. (2005) Optimal thyrotropin level: normal ranges and references intervals are not equivalent. Thyroid, 15, 1035 1039.
23. Alexander, E.K., Marqusee, E., Lawrence, J. et al. (2004) Timing and magnitude of increases in levothyroxine requirements during pregnancy in women with hypothyroidism. New England Journal of Medicine, 351, 241 249.
24. Rotondi, M., Mazziotti, G., Sorvillo, F. et al. (2004) Effects of increased thyroxine dosage pre-conception on thyroid function during early pregnancy. European Journal of Endocrinology, 151, 695 700.
25. Abalovich, M., Amino, N., Barbour, L.A. et al. (2007) Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism, 92, s1 s7.
26. Zigman, J.M., Cohen, S.E. Garber, J.R. (2003) Impact of thyroxine-binding globulin on thyroid hormone economy during pregnancy. Thyroid, 13, 1169 1175.