Synthesis and biological evaluation of new enantiomerically pure azole derivatives as inhibitors of Mycobacterium tuberculosis

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 8, 2009, Pages 2203-2205

  Castagnolo, Daniele ^a   Radi, Marco ^a   Dessì, Filippo ^a   Manetti, Fabrizio ^a   Saddi, Manuela ^b   Meleddu, Rita ^b   Logu, Alessandro De ^b   Botta, Maurizio ^a,c  

^a UNIVERSITY OF SIENA   (Italy)

^b UNIVERSITY OF CAGLIARI   (Italy)

^c TEMPLE UNIVERSITY   (United States)

Author keywords

Antifungal agents; Azole; Click chemistry; Tuberculosis

Indexed keywords

ANTIFUNGAL AGENT; CLOTRIMAZOLE; ECONAZOLE; ISONIAZID; PYRROLE DERIVATIVE; RIFAMPICIN;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG PURIFICATION; DRUG STRUCTURE; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROWAVE IRRADIATION; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; ONE POT SYNTHESIS;

ANTITUBERCULAR AGENTS; AZOLES; DRUG EVALUATION, PRECLINICAL; MICROBIAL SENSITIVITY TESTS; MYCOBACTERIUM TUBERCULOSIS; STEREOISOMERISM;

MYCOBACTERIUM TUBERCULOSIS;

EID: 63149142769     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.02.101     Document Type: Article

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