Imatinib inhibits in vitro proliferation of cells derived from a pleural solitary fibrous tumor expressing platelet-derived growth factor receptor-beta

Lung Cancer

Volumn 64, Issue 2, 2009, Pages 244-246

  Prunotto, Marco ^a   Bosco, Martino ^a   Daniele, Lorenzo ^a   Macri', Luigia ^a   Bonello, Lisa ^a   Schirosi, Laura ^b   Rossi, Giulio ^b   Filosso, Pierluigi ^a   Mussa, Baudolino ^a   Sapino, Anna ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Gleevec; Imatinib; Mutational analysis; PDGFR; Pleura; Solitary fibrous tumor

Indexed keywords

CISPLATIN; FLUOROURACIL; IMATINIB; KI 67 ANTIGEN; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SMOOTH MUSCLE ACTIN;

AGED; ANAMNESIS; ARTICLE; CANCER RADIOTHERAPY; CANCER RECURRENCE; CASE REPORT; CLINICAL FEATURE; CONTROLLED STUDY; DRUG MECHANISM; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SOLITARY FIBROUS TUMOR; THORACOTOMY;

AGED; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; BLOTTING, WESTERN; CELL PROLIFERATION; CELLS, CULTURED; CISPLATIN; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; FLUOROURACIL; HUMANS; NEOPLASM RECURRENCE, LOCAL; PIPERAZINES; PNEUMONECTOMY; PYRIMIDINES; RADIOTHERAPY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; SOLITARY FIBROUS TUMOR, PLEURAL;

EID: 63049126053     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2008.10.013     Document Type: Article

References (16)

1. Klemperer P., and Rabin L.B. Primary neoplasms of the pleura A report of five cases. Arch Pathol 11 (1931) 385-412
2. Hiraoka K., Morikawa T., Ohbuchi T., and Katoh H. Solitary fibrous tumors of the pleura: clinicopathological and immunohistochemical examination. Interact Cardiovasc Thorac Surg 2 (2003) 61-64
3. Nielsen G.P., O'Connell J.X., Dickersin G.R., and Rosenberg A.E. Solitary fibrous tumor of soft tissue: a report of 15 cases, including 5 malignant examples with light microscopic, immunohistochemical, and ultrastructural data. Mod Pathol 10 (1997) 1028-1037
4. Deniz K., Kontas O., Tucer B., and Kurtsoy A. Meningeal solitary fibrous tumor: report of a case and literature review. Folia Neuropathol 43 (2005) 178-185
5. Rodriguez I., Ayala E., Caballero C., De Miguel C., Matias-Guiu X., Cubilla A.L., et al. Solitary fibrous tumor of the thyroid gland: report of seven cases. Am J Surg Pathol 25 (2001) 1424-1428
6. Fukunaga M., Naganuma H., Nikaido T., Harada T., and Ushigome S. Extrapleural solitary fibrous tumor: a report of seven cases. Mod Pathol 10 (1997) 443-450
7. de Perrot M., Fischer S., Brundler M.A., Sekine Y., and Keshavjee S. Solitary fibrous tumors of the pleura. Ann Thorac Surg 74 (2002) 285-293
8. Cardillo G., Facciolo F., Cavazzana A.O., Capece G., Gasparri R., and Martelli M. Localized (solitary) fibrous tumors of the pleura: an analysis of 55 patients. Ann Thorac Surg 70 (2000) 1808-1812
9. de Perrot M., Kurt A.M., Robert J.H., Borisch B., and Spiliopoulos A. Clinical behavior of solitary fibrous tumors of the pleura. Ann Thorac Surg 67 (1999) 1456-1459
10. Rossi G., Schirosi L., Giovanardi F., Sartori G., Paci M., and Cavazza A. Pleural malignant solitary fibrous tumor with sarcomatous overgrowth showing PDGFRbeta mutation. Chest 130 (2006) 581-583
11. McArthur G.A., Demetri G.D., van Oosterom A., Heinrich M.C., Debiec-Rychter M., Corless C.L., et al. Molecular and clinical analysis of locally advanced dermatofibrosarcoma protuberans treated with imatinib: Imatinib Target Exploration Consortium Study B2225. J Clin Oncol 23 (2005) 866-873
12. Espana E.M., Kawakita T., Liu C.Y., and Tseng S.C. CD-34 expression by cultured human keratocytes is downregulated during myofibroblast differentiation induced by TGF-beta1. Invest Ophthalmol Vis Sci 45 (2004) 2985-2991
13. De Pas T., Toffalorio F., Colombo P., Trifiro G., Pelosi G., Vigna P.D., et al. Brief report: activity of imatinib in a patient with platelet-derived-growth-factor receptor positive malignant solitary fibrous tumor of the pleura. J Thorac Oncol 3 (2008) 938-941
14. Desmouliere A., Geinoz A., Gabbiani F., and Gabbiani G. Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol 122 (1993) 103-111
15. Thannickal V.J., Lee D.Y., White E.S., Cui Z., Larios J.M., Chacon R., et al. Myofibroblast differentiation by transforming growth factor-beta1 is dependent on cell adhesion and integrin signaling via focal adhesion kinase. J Biol Chem 278 (2003) 12384-12389
16. Rubin B.P., Singer S., Tsao C., Duensing A., Lux M.L., Ruiz R., et al. KIT activation is a ubiquitous feature of gastrointestinal stromal tumors. Cancer Res 61 (2001) 8118-8121