Platelet adhesion to multimerin 1 in vitro: Influences of platelet membrane receptors, von Willebrand factor and shear

Journal of Thrombosis and Haemostasis

Volumn 7, Issue 4, 2009, Pages 685-692

  Tasneem, S ^a   Adam, F ^a   Minullina, I ^a   Pawlikowska, M ^a   Hui, S K ^b   Zheng, S ^a   Miller, J L ^b   Hayward, Catherine P M ^a,c,d  

^a MCMASTER UNIVERSITY   (Canada)

^b UNIVERSITY OF CHICAGO   (United States)

^c HAMILTON REGIONAL LABORATORY MEDICINE PROGRAM   (Canada)

^d MCMASTER UNIVERSITY MEDICAL CENTRE   (Canada)

Author keywords

v 3; Collagen; Glycoprotein Ib multimerin 1; Platelet adhesion; von Willebrand factor

Indexed keywords

ALPHA5 INTEGRIN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; GLYCOPROTEIN IB ALPHA; MEMBRANE RECEPTOR; MULTIMERIN PROTEIN; UNCLASSIFIED DRUG; VASCULAR ADHESION PROTEIN 1; VON WILLEBRAND FACTOR;

ARTICLE; CONTROLLED STUDY; GLANZMANN DISEASE; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; REGULATORY MECHANISM; SHEAR RATE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; THROMBOCYTE AGGREGATION; THROMBOCYTE MEMBRANE; VON WILLEBRAND DISEASE;

BLOOD PLATELETS; BLOOD PROTEINS; CASE-CONTROL STUDIES; COLLAGEN TYPE I; COLLAGEN TYPE III; HUMANS; PERFUSION; PLATELET ADHESIVENESS; RECEPTORS, CELL SURFACE; THROMBASTHENIA; VON WILLEBRAND DISEASE; VON WILLEBRAND FACTOR;

EID: 63049084005     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1111/j.1538-7836.2009.03284.x     Document Type: Article

References (45)

1. Jeimy SB, Tasneem S, Cramer EM, Hayward CP. Multimerin 1. Platelets 2008; 19: 83-95.
2. Hayward CP, Hassell JA, Denomme GA, Rachubinski RA, Brown C, Kelton JG. The cDNA sequence of human endothelial cell multimerin. A unique protein with RGDS, coiled-coil, and epidermal growth factor-like domains and a carboxyl terminus similar to the globular domain of complement C1q and collagens type VIII and X. J Biol Chem 1995; 270: 18246-51.
3. Adam F, Zheng S, Joshi N, Kelton DS, Sandhu A, Suehiro Y, Jeimy SB, Santos AV, Masse JM, Kelton JG, Cramer EM, Hayward CP. Analyses of cellular multimerin 1 receptors: In vitro evidence of binding mediated by alphaIIbbeta3 and alphavbeta3. Thromb Haemost 2005; 94: 1004-11.
4. Hayward CP, Cramer EM, Song Z, Zheng S, Fung R, Masse JM, Stead RH, Podor TJ. Studies of multimerin in human endothelial cells. Blood 1998; 91: 1304-17.
5. Hayward CP, Bainton DF, Smith JW, Horsewood P, Stead RH, Podor TJ, Warkentin TE, Kelton JG. Multimerin is found in the alpha-granules of resting platelets and is synthesized by a megakaryocytic cell line. J Clin Invest 1993; 91: 2630-9.
6. Ruggeri ZM, Mendolicchio GL. Adhesion mechanisms in platelet function. Circ Res 2007; 100: 1673-85.
7. Beumer S, Heijnen HF, IJsseldijk MJ, Orlando E, de Groot PG, Sixma JJ. Platelet adhesion to fibronectin in flow: The importance of von Willebrand factor and glycoprotein Ib. Blood 1995; 86: 3452-60.
8. Saelman EU, Nieuwenhuis HK, Hese KM, de Groot PG, Heijnen HF, Sage EH, Williams S, McKeown L, Gralnick HR, Sixma JJ. Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (alpha 2 beta 1-integrin). Blood 1994; 83: 1244-50.
9. Jurk K, Clemetson KJ, de Groot PG, Brodde MF, Steiner M, Savion N, Varon D, Sixma JJ, Van Aken H, Kehrel BE. Thrombospondin-1 mediates platelet adhesion at high shear via glycoprotein Ib (GPIb): An alternative/backup mechanism to von Willebrand factor. FASEB J 2003; 17: 1490-2.
10. Savage B, Saldivar E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell 1996; 84: 289-97.
11. Hindriks G, IJsseldijk MJ, Sonnenberg A, Sixma JJ, de Groot PG. Platelet adhesion to laminin: Role of Ca2+ and Mg2+ ions, shear rate, and platelet membrane glycoproteins. Blood 1992; 79: 928-35.
12. Farndale RW, Sixma JJ, Barnes MJ, de Groot PG. The role of collagen in thrombosis and hemostasis. J Thromb Haemost 2004; 2: 561-73.
13. Denis C, Methia N, Frenette PS, Rayburn H, Ullman-Cullere M, Hynes RO, Wagner DD. A mouse model of severe von Willebrand disease: Defects in hemostasis and thrombosis. Proc Natl Acad Sci USA 1998; 95: 9524-9.
14. Ni H, Denis CV, Subbarao S, Degen JL, Sato TN, Hynes RO, Wagner DD. Persistence of platelet thrombus formation in arterioles of mice lacking both von Willebrand factor and fibrinogen. J Clin Invest 2000; 106: 385-92.
15. Bergmeier W, Piffath CL, Goerge T, Cifuni SM, Ruggeri ZM, Ware J, Wagner DD. The role of platelet adhesion receptor GPIbalpha far exceeds that of its main ligand, von Willebrand factor, in arterial thrombosis. Proc Natl Acad Sci USA 2006; 103: 16900-5.
16. Shen Y, Romo GM, Dong JF, Schade A, McIntire LV, Kenny D, Whisstock JC, Berndt MC, Lopez JA, Andrews RK. Requirement of leucine-rich repeats of glycoprotein (GP) Ibalpha for shear-dependent and static binding of von Willebrand factor to the platelet membrane GP Ib-IX-V complex. Blood 2000; 95: 903-10.
17. Hayward CP, Smith JW, Horsewood P, Warkentin TE, Kelton JG. p-155, a multimeric platelet protein that is expressed on activated platelets. J Biol Chem 1991; 266: 7114-20.
18. Hayward CP, Song Z, Zheng S, Fung R, Pai M, Masse JM, Cramer EM. Multimerin processing by cells with and without pathways for regulated protein secretion. Blood 1999; 94: 1337-47.
19. Hayward CP, Fuller N, Zheng S, Adam F, Jeimy SB, Horsewood I, Quinn-Allen MA, Kane WH. Human platelets contain forms of factor V in disulfide-linkage with multimerin. Thromb Haemost 2004; 92: 1349-57.
20. Miller JL, Cunningham D, Lyle VA, Finch CN. Mutation in the gene encoding platelet glycoprotein Ibα in platelet-type von Willebrand disease. Proc Natl Acad Sci USA 1991; 88: 4761-5.
21. Russell SD, Roth GJ. Pseudo-von Willebrand disease: A mutation in the platelet glycoprotein Ibα gene associated with a hyperactive surface receptor. Blood 1993; 81: 1787-91.
22. Miller JL, Castella A. Platelet-type von Willebrand's disease: characterization of a new bleeding disorder. Blood 1982; 60: 790-4.
23. Weiss HJ, Meyer D, Rabinowitz R, Pietu G, Girma JP, Vicic WJ, Rogers J. Pseudo von Willebrand's disease: An intrinsic platelet defect with aggregation by unmodified human factor VIII/von Willebrand factor and enhanced adsorption of its high-molecular-weight multimers. N Engl J Med 1982; 306: 326-62.
24. Jeimy SB, Fuller N, Tasneem S, Segers K, Stafford AR, Weitz JI, Camire RM, Nicolaes GA, Hayward CP. Multimerin 1 binds factor V and activated factor V with high affinity and inhibits thrombin generation. Thromb Haemost 2008; 100: 1058-67.
25. Kinlough-Rathbone RL, Perry DW, Rand ML, Packham MA. Responses to aggregating agents after cleavage of GPIb of human platelets by the O-sialoglycoprotein endoprotease from Pasteurella haemolytica-potential surrogates for Bernard-Soulier platelets? Thromb Res 2000; 99: 165-72.
26. Konstantopoulos K, Kamat SG, Schafer AI, Banez EI, Jordan R, Kleiman NS, Hellums JD. Shear-induced platelet aggregation is inhibited by in vivo infusion of an anti-glycoprotein IIb/IIIa antibody fragment, c7E3 Fab, in patients undergoing coronary angioplasty. Circulation 1995; 91: 1427-31.
27. Nesbitt WS, Giuliano S, Kulkarni S, Dopheide SM, Harper IS, Jackson SP. Intercellular calcium communication regulates platelet aggregation and thrombus growth. J Cell Biol 2003; 160: 1151-61.
28. Kulkarni S, Nesbitt WS, Dopheide SM, Hughan SC, Harper IS, Jackson SP. Techniques to examine platelet adhesive interactions under flow. Methods Mol Biol 2004; 272: 165-86.
29. van der Plas RM, Gomes L, Marquart JA, Vink T, Meijers JC, de Groot PG, Sixma JJ, Huizinga EG. Binding of von Willebrand factor to collagen type III: Role of specific amino acids in the collagen binding domain of vWF and effects of neighboring domains. Thromb Haemost 2000; 84: 1005-11.
30. Jeimy SB, Woram RA, Fuller N, Quinn-Allen MA, Nicolaes GA, Dahlback B, Kane WH, Hayward CP. Identification of the MMRN1 binding region within the C2 domain of human factor V. J Biol Chem 2004; 279: 51466-71.
31. Romijn RA, Bouma B, Wuyster W, Gros P, Kroon J, Sixma JJ, Huizinga EG. Identification of the collagen-binding site of the von Willebrand factor A3-domain. J Biol Chem 2001; 276: 9985-91.
32. Bergmeier W, Chauhan AK, Wagner DD. Glycoprotein Ibalpha and von Willebrand factor in primary platelet adhesion and thrombus formation: lessons from mutant mice. Thromb Haemost 2008; 99: 264-70.
33. Romo GM, Dong JF, Schade AJ, Gardiner EE, Kansas GS, Li CQ, McIntire LV, Berndt MC, Lopez JA. The glycoprotein Ib-IX-V complex is a platelet counterreceptor for P-selectin. J Exp Med 1999; 190: 803-14.
34. Kulkarni S, Dopheide SM, Yap CL, Ravanat C, Freund M, Mangin P, Heel KA, Street A, Harper IS, Lanza F, Jackson SP. A revised model of platelet aggregation. J Clin Invest 2000; 105: 783-91.
35. Inoue O, Suzuki-Inoue K, Ozaki Y. Redundant mechanism of platelet adhesion to laminin and collagen under flow: Involvement of von Willebrand factor and glycoprotein Ib-IX-V. J Biol Chem 2008; 283: 16279-82.
36. Merten M, Chow T, Hellums JD, Thiagarajan P. A new role for P-selectin in shear-induced platelet aggregation. Circulation 2000; 102: 2045-50.
37. Coller BS, Cheresh DA, Asch E, Seligsohn U. Platelet vitronectin receptor expression differentiates Iraqi-Jewish from Arab patients with Glanzmann thrombasthenia in Israel. Blood 1991; 77: 75-83.
38. Kasirer-Friede A, Kahn ML, Shattil SJ. Platelet integrins and immunoreceptors. Immunol Rev 2007; 218: 247-64.
39. Ni H, Freedman J. Platelets in hemostasis and thrombosis: Role of integrins and their ligands. Transfus Apher Sci 2003; 28: 257-64.
40. Sixma JJ, van Zanten GH, Huizinga EG, van der Plas RM, Verkley M, Wu YP, Gros P, de Groot PG. Platelet adhesion to collagen: An update. Thromb Haemost 1997; 78: 434-8.
41. Cho J, Mosher DF. Impact of fibronectin assembly on platelet thrombus formation in response to type I collagen and von Willebrand factor. Blood 2006; 108: 2229-36.
42. Ni H, Yuen PS, Papalia JM, Trevithick JE, Sakai T, Fassler R, Hynes RO, Wagner DD. Plasma fibronectin promotes thrombus growth and stability in injured arterioles. Proc Natl Acad Sci USA 2003; 100: 2415-9.
43. Hayward CP, Rivard GE, Kane WH, Drouin J, Zheng S, Moore JC, Kelton JG. An autosomal dominant, qualitative platelet disorder associated with multimerin deficiency, abnormalities in platelet factor V, thrombospondin, von Willebrand factor, and fibrinogen and an epinephrine aggregation defect. Blood 1996; 87: 4967-78.
44. Hayward CP, Weiss HJ, Lages B, Finlay M, Hegstad AC, Zheng S, Cowie A, Masse JM, Harrison P, Cramer EM. The storage defects in grey platelet syndrome and alphadelta-storage pool deficiency affect alpha-granule factor V and multimerin storage without altering their proteolytic processing. Br J Haematol 2001; 113: 871-7.
45. Specht CG, Schoepfer R. Deletion of multimerin-1 in alpha-synuclein-deficient mice. Genomics 2004; 83: 1176-8.