Pain on injection with microemulsion propofol

British Journal of Clinical Pharmacology

Volumn 67, Issue 3, 2009, Pages 316-325

  Sim, Ji Yeon ^a   Lee, Soo Han ^a   Park, Do Yang ^a   Jung, Jin Ah ^a   Ki, Kyoung Ho ^a   Lee, Dong Ho ^a   Noh, Gyu Jeong ^a  

^a University of Ulsan College of Medicine   (South Korea)

Author keywords

Injection pain; Microemulsion propofol

Indexed keywords

AQUAFOL; BRADYKININ; EPHEDRINE; KETAMINE; LIDOCAINE; LIPID EMULSION; MACPERAN; MACROGOL; METOCLOPRAMIDE; ONDANSETRON; PENTOTAL; POLYETHYLENEGLYCOL 660 HYDROXYSTEARATE; PROPOFOL; THIOPENTAL; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BLOOD LEVEL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DISEASE SEVERITY; DRUG EFFECT; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; INCIDENCE; INJECTION SITE PAIN; MAJOR CLINICAL STUDY; MALE; MICROEMULSION; MULTICENTER STUDY; NORMAL HUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; VISUAL ANALOG SCALE;

ADULT; AGED; AGED, 80 AND OVER; BRADYKININ; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; EMULSIONS; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; PAIN; PAIN MEASUREMENT; PROPOFOL; SINGLE-BLIND METHOD; YOUNG ADULT;

EID: 62949129172     PISSN: 03065251     EISSN: 13652125     Source Type: Journal    
DOI: 10.1111/j.1365-2125.2008.03358.x     Document Type: Article

References (42)

1. Devlin JW, Lau AK, Tanios MA. Propofol-associated hypertriglyceridemia and pancreatitis in the intensive care unit: an analysis of frequency and risk factors. Pharmacotherapy 2005 25 : 1348 52.
2. Baker MT, Naguib M. Propofol: the challenges of formulation. Anesthesiology 2005 103 : 860 76.
3. Picard P, Tramer MR. Prevention of pain on injection with propofol: a quantitative systematic review. Anesth Analg 2000 90 : 963 9.
4. Kim KM, Choi BM, Park SW, Lee SH, Christensen LV, Zhou J, Yoo BH, Shin HW, Bae KS, Kern SE, Kang SH, Noh GJ. Pharmacokinetics and pharmacodynamics of propofol microemulsion and lipid emulsion after an intravenous bolus and variable rate infusion. Anesthesiology 2007 106 : 924 34.
5. Klement W, Arndt JO. Pain on injection of propofol: effects of concentration and diluent. Br J Anaesth 1991 67 : 281 4.
6. Doenicke AW, Roizen MF, Rau J, Kellermann W, Babl J. Reducing pain during propofol injection: the role of the solvent. Anesth Analg 1996 82 : 472 4.
7. Scott RP, Saunders DA, Norman J. Propofol: clinical strategies for preventing the pain of injection. Anaesthesia 1988 43 : 492 4.
8. Dubey PK, Kumar A. Pain on injection of lipid-free propofol and propofol emulsion containing medium-chain triglyceride: a comparative study. Anesth Analg 2005 101 : 1060 2.
9. Iwama H, Nakane M, Ohmori S, Kaneko T, Kato M, Watanabe K, Okuaki A. Nafamostat mesilate, a kallikrein inhibitor, prevents pain on injection with propofol. Br J Anaesth 1998 81 : 963 4.
10. Song D, Hamza M, White PF, Klein K, Recart A, Khodaparast O. The pharmacodynamic effects of a lower-lipid emulsion of propofol: a comparison with the standard propofol emulsion. Anesth Analg 2004 98 : 687 91.
11. Soltesz S, Silomon M, Graf G, Mencke T, Boulaadass S, Molter GP. Effect of a 0.5% dilution of propofol on pain on injection during induction of anesthesia in children. Anesthesiology 2007 106 : 80 4.
12. Brazeau GA, Cooper B, Svetic KA, Smith CL, Gupta P. Current perspectives on pain upon injection of drugs. J Pharm Sci 1998 87 : 667 77.
13. Agarwal A, Ansari MF, Gupta D, Pandey R, Raza M, Singh PK, Shiopriye, Dhiraj S, Singh U. Pretreatment with thiopental for prevention of pain associated with propofol injection. Anesth Analg 2004 98 : 683 6.
14. Koo SW, Cho SJ, Kim YK, Ham KD, Hwang JH. Small-dose ketamine reduces the pain of propofol injection. Anesth Analg 2006 103 : 1444 7.
15. Apiliogullari S, Keles B, Apiliogullari B, Balasar M, Yilmaz H, Duman A. Comparison of diphenhydramine and lidocaine for prevention of pain after injection of propofol: a double-blind, placebo-controlled, randomized study. Eur J Anaesthesiol 2007 24 : 235 8.
16. Fujii Y, Uemura A. Effect of metoclopramide on pain on injection of propofol. Anaesth Intensive Care 2004 32 : 653 6.
17. Ambesh SP, Dubey PK, Sinha PK. Ondansetron pretreatment to alleviate pain on propofol injection: a randomized, controlled, double-blinded study. Anesth Analg 1999 89 : 197 9.
18. Cheong MA, Kim KS, Choi WJ. Ephedrine reduces the pain from propofol injection. Anesth Analg 2002 95 : 1293 6.
19. Larsen B, Beerhalter U, Biedler A, Brandt A, Doege F, Brun K, Erdkonig R, Larsen R Less pain on injection by a new formulation of propofol? A comparison with propofol LCT Anaesthesist 2001 50 : 842 5.
20. Collins SL, Moore RA, McQuay HJ. The visual analogue pain intensity scale: what is moderate pain in millimetres? Pain 1997 72 : 95 7.
21. Yamakage M, Iwasaki S, Satoh J, Namiki A. Changes in concentrations of free propofol by modification of the solution. Anesth Analg 2005 101 : 385 8.
22. Tan LH, Hwang NC. The effect of mixing lidocaine with propofol on the dose of propofol required for induction of anesthesia. Anesth Analg 2003 97 : 461 4.
23. Ruzilawati AB, Wahab MS, Imran A, Ismail Z, Gan SH. Method development and validation of repaglinide in human plasma by HPLC and its application in pharmacokinetic studies. J Pharm Biomed Anal 2007 43 : 1831 5.
24. Shimamoto K, Iimura O. Measurement of circulating kinins, their changes by inhibition of kininase II and their possible blood pressure lowering effect. Agents Actions 1987 22 : 297 307.
25. Ohmizo H, Obara S, Iwama H. Mechanism of injection pain with long and long-medium chain triglyceride emulsive propofol. Can J Anaesth 2005 52 : 595 9.
26. Lee EH, Lee SH, Park DY, Ki KH, Lee EK, Lee DH, Noh GJ. Physicochemical properties, pharmacokinetics, and pharmacodynamics of a reformulated microemulsion propofol in rats. Anesthesiology 2008 109 : 436 47.
27. Macario A, Weinger M, Truong P, Lee M. Which clinical anesthesia outcomes are both common and important to avoid? The perspective of a panel of expert anesthesiologists. Anesth Analg 1999 88 : 1085 91.
28. Briggs LP, Clarke RS, Dundee JW, Moore J, Bahar M, Wright PJ. Use of di-isopropyl phenol as main agent for short procedures. Br J Anaesth 1981 53 : 1197 202.
29. Nakane M, Iwama H. A potential mechanism of propofol-induced pain on injection based on studies using nafamostat mesilate. Br J Anaesth 1999 83 : 397 404.
30. Tan CH, Onsiong MK. Pain on injection of propofol. Anaesthesia 1998 53 : 468 76.
31. Wang H, Cork R, Rao A. Development of a new generation of propofol. Curr Opin Anaesthesiol 2007 20 : 311 5.
32. Moreau ME, Garbacki N, Molinaro G, Brown NJ, Marceau F, Adam A. The kallikrein-kinin system: current and future pharmacological targets. J Pharmacol Sci 2005 99 : 6 38.
33. Kaplan AP, Joseph K, Shibayama Y, Reddigari S, Ghebrehiwet B, Silverberg M. The intrinsic coagulation/kinin-forming cascade: assembly in plasma and cell surfaces in inflammation. Adv Immunol 1997 66 : 225 72.
34. Kaplan AP, Joseph K, Silverberg M. Pathways for bradykinin formation and inflammatory disease. J Allergy Clin Immunol 2002 109 : 195 209.
35. Zhao Y, Qiu Q, Mahdi F, Shariat-Madar Z, Rojkjaer R, Schmaier AH. Assembly and activation of HK-PK complex on endothelial cells results in bradykinin liberation and NO formation. Am J Physiol Heart Circ Physiol 2001 280 : H1821 9.
36. Eriksson M, Englesson S, Niklasson F, Hartvig P. Effect of lignocaine and pH on propofol-induced pain. Br J Anaesth 1997 78 : 502 6.
37. Knibbe CA, Voortman HJ, Aarts LP, Kuks PF, Lange R, Langemeijer HJ, Danhof M. Pharmacokinetics, induction of anaesthesia and safety characteristics of propofol 6% SAZN vs propofol 1% SAZN and Diprivan-10 after bolus injection. Br J Clin Pharmacol 1999 47 : 653 60.
38. McCrirrick A, Hunter S. Pain on injection of propofol: the effect of injectate temperature. Anaesthesia 1990 45 : 443 4.
39. Fletcher GC, Gillespie JA, Davidson JA. The effect of temperature upon pain during injection of propofol. Anaesthesia 1996 51 : 498 9.
40. McCulloch MJ, Lees NW. Assessment and modification of pain on induction with propofol (Diprivan). Anaesthesia 1985 40 : 1117 20.
41. Suzuki H, Miyazaki H, Andoh T, Yamada Y. Propofol formulated with long-/medium-chain triglycerides reduces the pain of injection by target controlled infusion. Acta Anaesthesiol Scand 2006 50 : 568 71.
42. Klement W, Arndt JO. Pain on i. Br J Anaesth 1991 66 : 189 95.