A new scale measuring psychologic impact of genetic susceptibility testing for Alzheimer disease

Alzheimer Disease and Associated Disorders

Volumn 23, Issue 1, 2009, Pages 50-56

  Chung, Winston W ^a   Chen, Clara A ^c   Cupples, L Adrienne ^a   Roberts, J Scott ^d   Hiraki, Susan C ^a   Nair, Anil K ^a   Green, Robert C ^a,b   Stern, Robert A ^a,b  

^a Department of Neurology ^*

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF MICHIGAN SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Alzheimer disease genetics; Alzheimer disease risk assessment; Genetic testing

Indexed keywords

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CONSTRUCT VALIDITY; CRONBACH ALPHA COEFFICIENT; DISEASE COURSE; FEMALE; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PSYCHOLOGICAL ASPECT; PSYCHOMETRY; RELIABILITY; RISK ASSESSMENT; SELF REPORT;

ALZHEIMER DISEASE; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; QUESTIONNAIRES;

EID: 62949089253     PISSN: 08930341     EISSN: None     Source Type: Journal    
DOI: 10.1097/WAD.0b013e318188429e     Document Type: Article

References (31)

1. Green RC. Diagnosis and Management of Ahheimer's Disease and Other Dementias. 2nd ed. Caddo OK: Professional Communications Inc; 2005.
2. Hebert LE, Scherr PA, Bienias JL, et al. Alzheimer disease in the US population: prevalence estimates using the 2000 census. Arch Neurol. 2003;60:1119-1122.
3. Sloane PD, Zimmerman S, Suchindran C, et al. The public health impact of Alzheimer's disease, 2000-2050: potential implication of treatment advances. Annu Rev Public Health. 2002;23:213-231.
4. Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA. 1997; 278:1349-1356.
5. Rogaeva E, Meng Y, Lee JH, et al. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nat Genet. 2007;39:168-177.
6. Brodaty H, Conneally M, Gauthier S, et al. Consensus statement on predictive testing for Alzheimer disease. Alzheimer Dis Assoc Disord. 1995;9:182-187.
7. Farrer LA, Brin MF, Elsas L, et al. Statement on use of apolipoprotein E testing for Alzheimer's disease. JAMA. 1995; 274:1627-1629.
8. Post SG, Whitehouse PJ, Binstock RH, et al. The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective. JAMA. 1997;277:832-836.
9. Relkin NR, Kwon YJ, Tsai J, et al. The National Institute on Aging/Alzheimer's Association recommendations on the application of apolipoprotein E genotyping to Alzheimer's disease. Ann N Y Acad Sci. 1996;802:149-176.
10. Brown T, Roberts JS, LaRusse S, et al. Impact of genetic risk assessment for Alzheimer's disease. J Genet Couns. 2002;11: 446-447.
11. Roberts JS, Green RC, Relkin NR, et al. How do participants rate the impact of genetic susceptibility testing for Alzheimer's disease? Neurology. 2003;60:A453.
12. Roberts JS, Lock M, Prest J, et al. How does genetic testing affect anxiety about developing AD? Neurobiol Aging. 2004; 25(suppl 2):509.
13. Gooding HC, Linnenbringer EL, Burack J, et al. Genetic susceptibility testing for Alzheimer disease: motivation to obtain information and control as precursors to coping with increased risk. Patient Educ Couns. 2006;64:259-267.
14. Cella D, Hughes C, Peterman A, et al. A brief assessment of concerns associated with genetic testing for cancer: the Multidimensional Impact of Cancer Risk Assessment (MICRA) questionnaire. Health Psychol. 2002;21:564-572.
15. Leyfer OT, Ruberg JL, Woodruff-Borden J. Examination of the utility of the Beck Anxiety Inventory and its factors as a screener for anxiety disorders. J Anxiety Disord. 2006;20: 444-458.
16. Radloff L. The CES-D Scale: A Self-Report Depression Scale for Research in the General Population. Appl Psychol Meas. 1977;1:385-401.
17. Horowitz M, Wilner N, Alvarez W. Impact of Event Scale: a measure of subjective stress. Psychosom Med. 1979;41: 209-218.
18. Broadstock M, Michie S, Marteau T. Psychological consequences of predictive genetic testing: a systematic review. Eur J Hum Genet. 2000;8:731-738.
19. Sundin EC, Horowitz MJ. Impact of Event Scale: psychometric properties. Br J Psychiatry. 2002;180:205-209.
20. Read CY, Perry DJ, Duffy ME. Design and psychometric evaluation of the Psychological Adaptation to Genetic Information Scale. J Nurs Scholarsh. 2005;37:203-208.
21. Green RC, Roberts JS, Chen C, et al. Comparing the impact of a condensed vs extended protocol for disclosure of APOE to relatives of patients with AD: The REVEAL Study. Alzheimer Dement. 2007;3:S184.
22. Cattell RB. The Scree test for the number of factors. Multivariate Behav Res. 1966;1:245-276.
23. Cronbach LJ, Warrington WG. Time-limit tests: estimating their reliability and degree of speeding. Psychometrika. 1951; 16:167-188.
24. Zilberg NJ, Weiss DS, Horowitz MJ. Impact of Event Scale: a cross-validation study and some empirical evidence supporting a conceptual model of stress response syndromes. J Consult Clin Psychol. 1982;50:407-414.
25. Tennen H, Herzberger S. Impact of Events Scale. In: Sweetland RC, Keyser DJ, eds. Test Critiques. Kansas City, MO: Test Corporation of America; 1985:358-366.
26. Reichelt JG, Dahl AA, Heimdal K, et al. Uptake of genetic testing and pre-test levels of mental distress in Norwegian families with known BRCA1 mutations. Dis Markers. 1999;15:139-143.
27. Vernon SW, Gritz ER, Peterson SK, et al. Correlates of psychologic distress in colorectal cancer patients undergoing genetic testing for hereditary colon cancer. Health Psychol. 1997;16:73-86.
28. Corcoran K, Fisher J. Measures for Clinical Practice: A Source Book. New York: Free Press; 1987.
29. Santor DA, Zuroff DC, Ramsay JO, et al. Examining scale discriminability in the BDI and CES-D as a function of depressive severity. Psvchol Assess. 1995;7: 131-139.
30. Beck AT, Epstein N, Brown G, et al. An inventory for measuring clinical anxiety: psychometric properties. J Consult Clin Psychol. 1988;56:893-897.
31. Wetherell JL, Arean PA. Psychometric evaluation of the Beck Anxiety Inventory with older medical patients. Psychol Assess. 1997;9:136-144.