Angiotensin AT2 receptor agonists act as anti-opioids via EP3 receptor in mice

Peptides

Volumn 30, Issue 4, 2009, Pages 735-739

  Yamada, Yuko ^a   Ohinata, Kousaku ^a   Lipkowski, Andrzej W ^b   Yoshikawa, Masaaki ^a,c  

^a KYOTO UNIVERSITY   (Japan)

^b MOSSAKOWSKI MEDICAL RESEARCH CENTRE   (Poland)

^c OSAKA UNIVERSITY   (Japan)

Author keywords

Angiotensin II; Anti opioid effect; AT2 receptor; EP3 receptor; Prostaglandin E2; Tail pinch test

Indexed keywords

1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; [4 AMINOPHENYLALANINE 6] ANGIOTENSIN II; ANGIOTENSIN 2 RECEPTOR ANTAGONIST; ANGIOTENSIN II; DELTA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR AGONIST; MORPHINE; MU OPIATE RECEPTOR; NOVOKININ; PROSTAGLANDIN E RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINOCICEPTION; AREA UNDER THE CURVE; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG ANTAGONISM; DRUG INHIBITION; LABORATORY TEST; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANGIOTENSIN II; ANIMALS; MALE; MICE; NARCOTIC ANTAGONISTS; OPIOID PEPTIDES; PROSTAGLANDIN ANTAGONISTS; RECEPTORS, ANGIOTENSIN; RECEPTORS, PROSTAGLANDIN E;

MUS;

EID: 62749168906     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2008.11.011     Document Type: Article

References (31)

1. Bhargava H.N., and Das S. Evidence for opiate action at the brain receptors for thyrotropin-releasing hormone. Brain Res 368 (1986) 262-267
2. Bley K.R., Hunter J.C., Eglen R.M., and Smith J.A. The role of IP prostanoid receptors in inflammatory pain. Trends Pharmacol Sci 19 (1998) 141-147
3. Häuser W., Jöhren O., and Saavedra J.M. Characterization and distribution of angiotensin II receptor subtypes in the mouse brain. Eur J Pharmacol 348 (1998) 101-114
4. 2. Ann N Y Acad Sci 917 (2000) 106-120
5. 2 in the brain. Ann N Y Acad Sci 840 (1998) 269-281
6. 3 subtype is involved in thermal hyperalgesia through its actions in the preoptic hypothalamus and the diagonal band of Broca in rats. Pain 71 (1997) 303-311
7. Kaneko S., Mori A., Tamura S., Satoh M., and Takagi H. Intracerebroventricular administration of angiotensin II attenuates morphine-induced analgesia in mice. Neuropharmacology 24 (1985) 1131-1134
8. Kaneko S., Tamura S., and Takagi H. Purification and identification of endogenous anti-opioid substances from bovine brain. Biochem Biophys Res Commun 126 (1985) 587-593
9. 2 receptor in the brain in regulation of blood pressure and water intake. Am J Physiol Heart Circ Physiol 284 (2003) 116-121
10. 2 receptor affinity. Bioorg Med Chem 11 (2003) 2947-2954
11. 3 receptor knockout mice. Br J Pharmacol 133 (2001) 438-444
12. Mogi M., Li J.M., Iwanami J., Min L.J., Tsukuda K., Iwai M., et al. Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2. Hypertension 48 (2006) 141-148
13. Narumiya S., and FitzGerald G.A. Genetic and pharmacological analysis of prostanoid receptor function. J Clin Invest 108 (2001) 25-30
14. Narumiya S., Sugimoto Y., and Ushikubi F. Prostanoid receptors: structures, properties, and functions. Physiol Rev 79 (1999) 1193-1226
15. 2-induced thermal hyperalgesia and its reversal by morphine in the warm-water tail-withdrawal procedure in rhesus monkeys. J Pharmacol Exp Ther 266 (1993) 1355-1363
16. 4 receptor in mice. FEBS Lett 5 (2008) 773-777
17. 3 receptors. Brain Res 663 (1994) 287-292
18. Pan W., and Kastin A.J. From MIF-1 to endomorphin: the Tyr-MIF-1 family of peptides. Peptides 28 (2007) 2411-2434
19. Pecchi E., Dallaporta M., Thirion S., Salvat C., Berenbaum F., Jean A., et al. Involvement of central microsomal prostaglandin E synthase-1 in IL-1β-induced anorexia. Physiol Genomics 25 (2006) 485-492
20. Pulichino A.M., Rowland S., Wu T., Clark P., Xu D., Mathieu M.C., et al. Audoly LP Prostacyclin antagonism reduces pain and inflammation in rodent models of hyperalgesia and chronic arthritis. J Pharmacol Exp Ther 319 (2006) 1043-1050
21. Saavedra J.M. Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities. Cell Mol Neurobiol 25 (2005) 485-512
22. Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ. Interleukin-1β-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity.
23. 6 angiotensin II. Biochem Biophys Res Commun 169 (1990) 997-1006
24. Takenaka Y., Nakamura F., Usui H., Lipkowski A.W., Toth G., and Yoshikawa M. Anti-analgesic activity of enterostatin (VPDPR) is mediated by corticosterone. Peptides 24 (2003) 735-829
25. von Bohlen und Halbach O., and Albrecht D. The CNS renin-angiotensin system. Cell Tissue Res 326 (2006) 599-616
26. Wiesenfeld-Hallin Z., de Araúja Lucas G., Alster P., Xu X.J., and Hökfelt T. Cholecystokinin/opioid interactions. Brain Res 848 1-2 (1999 Nov 27) 78-89
27. Wright J.W., and Harding J.W. The brain angiotensin system and extracellular matrix molecules in neural plasticity, learning, and memory. Prog Neurobiol 72 (2004) 263-293
28. Yamada Y., Matoba N., Usui H., Onishi K., and Yoshikawa M. Design of a highly potent anti-hypertensive peptide based on ovokinin(2-7). Biosci Biotechnol Biochem 66 (2002) 1213-1217
29. 2 receptor and prostaglandin IP receptor. Peptides 29 (2008) 412-418
30. 2- and IP-receptor-dependent mechanism in mesenteric artery from SHRs. Biosci Biotechnol Biochem 72 (2008) 257-259
31. Zhao M., Li Z., Peng L., Tang Y.R., Wang C., Zhang Z., et al. A new class of analgesic agents toward prostacyclin receptor inhibition: synthesis, biological studies and QSAR analysis of 1-hydroxyl-2-substituted phenyl-4,4,5,5- tetramethylimidazolines. Eur J Med Chem 43 (2008) 1048-1058