Prostaglandin E receptor EP3 subtype is involved in thermal hyperalgesia through its actions in the preoptic hypothalamus and the diagonal band of Broca in rats

Pain

Volumn 71, Issue 3, 1997, Pages 303-311

  Hosoi, M ^a   Oka, T ^a   Hori, T ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

Diagonal band of Broca; EP3 receptor; Hyperalgesia; M and B28767; Preoptic hypothalamus; Prostaglandin E2

Indexed keywords

11 DEOXY 16 PHENOXY 17,18,19,20 TETRANORPROSTAGLANDIN E1; BUTAPROST; PROSTAGLANDIN E; PROSTAGLANDIN E2; PROSTAGLANDIN E2 DERIVATIVE; PROSTAGLANDIN RECEPTOR; PROSTAGLANDIN RECEPTOR STIMULATING AGENT; PROSTANOID RECEPTOR; RECEPTOR SUBTYPE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DOSE RESPONSE; HYPERALGESIA; INFLAMMATION; INTRACEREBRAL DRUG ADMINISTRATION; MALE; MEDIAL PREOPTIC AREA; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0030743541     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3959(97)03380-0     Document Type: Article

References (41)

1. 1 receptor gene, Eur. J. Biochem., 231 (1995) 809–814.
2. Carstens, E., MacKinnon, J.D. and Guinan, M.J., Inhibition of spinal dorsal horn neuronal responses to noxious skin heating by medial preoptic and septal stimulation in the cat, J. Neurophysiol., 48 (1982) 981–991.
3. Davies, P., Bailey, P.J. and Goldenberg, M.M., The role of arachidonic acid oxygenation products in pain and inflammation, Annu. Rev. Immunol., 2 (1984) 335–357.
4. Gaudet, R.J., Alam, I. and Levine, L., Accumulation of cyclooxygenase products of arachidonic acid metabolism in gerbil brain during reperfusion after bilateral common carotid artery occlusion, J. Neurochem., 35 (1980) 653–658.
5. Giesler, G.J., Jr, Katter, J.T. and Dado, R.J., Direct spinal pathways to the limbic system for nociceptive information, Trends Neurosci., 17 (1994) 244–250.
6. 2 subtype, J. Biol. Chem., 268 (1993) 7759–7762.
7. Hori, T., Nakashima, T., Take, S., Kaizuka, Y., Mori, T. and Katafuchi, T., Immune cytokines and regulation of body temperature, food intake and cellular immunity, Brain Res. Bull., 27 (1994) 309–313.
8. 2-induced fever and changes in nociception in rats are mediated by different types of EP receptors, Abstract of the 26th Annual Meeting of Society for Neuroscience, Vol. 22–1 (1996) 88.
9. 2 α to conscious mice, Eur. J. Pharmacol., 122 (1986) 173–179.
10. Krayniak, P.F., Weiner, S. and Siegel, A., An analysis of the efferent connections of the septal area in the cat, Brain Res., 189 (1980) 15–29.
11. Kuehl, F.A. Jr. and Egan, R.W., Prostaglandins, arachidonic acid, and inflammation, Science, 210 (1980) 978–984.
12. 2 receptors in rat renal medulla, Arch. Biochem. Bio., 259 (1987) 89–97.
13. Martin, H.A., Basbaum, A.I., Kwiat, G.C., Goetzl, E.J. and Levine, J.D., Leukotriene and prostaglandin sensitization of cutaneous high-threshold C- and A- δ mechanonociceptors in the hairy skin of rat hindlimbs, Neuroscience, 22 (1987) 651–659.
14. 2 sensitivity of the organum vasculosum lamina terminalis region and preoptic area in rat brain slices, J. Physiol. (Lond.), 454 (1992) 213–230.
15. 2 microinjected into the preoptic area of rats, Brain Res., 444 (1988) 265–272.
16. 2 binding sites in rat brain using quantitative autoradiography, Brain Res., 581 (1992) 292–298.
17. 2 to mice, Br. J. Pharmacol., 112 (1994a) 735–740.
18. 2 to conscious mice, Pain, 57 (1994b) 217–223.
19. Mokha, S.S., Goldsmith, G.E., Hellon, R.F. and Puri, R., Hypothalamic control of nocireceptive and other neurones in the marginal layer of the dorsal horn of the medulla (trigeminal nucleus caudalis) in the rat, Exp. Brain Res., 65 (1987) 427–436.
20. 2 from rat hypothalamic explants in vitro, Neuroendocrinology, 56 (1992) 61–68.
21. 3 subtype, J. Biol. Chem., 268 (1993) 9517–9521.
22. 2 α and related enzymes in postmortem human brain, J. Neurochem., 43 (1984) 71–82.
23. 2 on pain and inflammation, Nippon Yakurigaku Zasshi, 33 (1983) 264–266.
24. 2-induced hyperthermia in rats, Am. J. Physiol., 267 (1994) R289–R294.
25. 2 induces hyperthermia in the rat, Neurosci. Res. Suppl., 19 (1994a) S233.
26. 3 receptors, Brain Res., 663 (1994b) 287–292.
27. Oka, T., Oka, K., Hosoi, M., Aou, S. and Hori, T., The opposing effects of interleukin-1 β microinjected into the preoptic hypothalamus and the ventromedial hypothalamus on nociceptive behavior in rats, Brain Res., 700 (1995) 271–278.
28. 2 induces bimodal effects on nociceptive neuronal responses in the trigeminal nucleus caudalis in rats: the possible involvement of different types of EP-receptors, Neurosci. Res. Suppl., 20 (1996) S218.
29. 2 in rats, Brain Res. (1997) in press.
30. Paxinos, G. and Watson, C., The Rat Brain in Stereotaxic Coordinates, Academic Press, 1986.
31. 2 α in the rat. I. Behavioral, antinociceptive and anticonvulsant actions of intraventricular prostaglandins in the rat, Psychopharmacology, 50 (1976) 89–94.
32. Rizvi, T.A., Ennis, M. and Shipley, M.T., Reciprocal connections between the medial preoptic area and the midbrain periaqueductal gray in rat: a WGA-HRP and PHA-L study, J. Comp. Neurol., 315 (1992) 1–15.
33. Robertson, R.P. and Little, S.A., Down-regulation of prostaglandin E receptors and homologous desensitization of isolated adipocytes, Endocrinology, 113 (1983) 1732–1738.
34. 2 subtype, Biochem. Biophys. Res. Commun., 200 (1994) 1329–1333.
35. 3 in the mouse nervous system, Neuroscience, 62 (1994) 919–928.
36. Swanson, L.W. and Cowan, W.M., The connections of the septal region in the rat, J. Comp. Neurol., 186 (1979) 621–656.
37. 2 α , Brain Res., 373 (1986) 81–84.
38. Ushikubi, F., Hirata, M. and Narumiya, S., Molecular biology of prostanoid receptors; an overview, J. Lipid Mediat., 12 (1995) 343–359.
39. Veening, J.G., Stroeken, P.C., Posthuma, P. and Steinbusch, H.W.M., A comparison of the descending hypothalamic and some other diencephalic projections to the nucleus raphe magnus and the mesencephalic periaqueductal gray in the rat, Neurosci. Res. Commun., 7 (1990) 123–132.
40. 2 binding sites in monkey diencephalon, J. Neurosci., 8 (1988) 2003–2010.
41. 2 α binding sites in monkey brain, Brain Res., 478 (1989) 143–148.