Determinants flanking the CD4 binding loop modulate macrophage tropism of human immunodeficiency virus type 1 R5 envelopes

Journal of Virology

Volumn 83, Issue 6, 2009, Pages 2575-2583

  Duenas Decamp, Maria José ^a   Peters, Paul J ^a   Burton, Dennis ^b   Clapham, Paul R ^a  

^a UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^b SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; IMMUNOGLOBULIN G; NEUTRALIZING ANTIBODY; THREONINE; VIRUS ENVELOPE PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING AFFINITY; BINDING SITE; BRAIN TISSUE; CHIMERA; GENETIC CONSERVATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; IMMUNE SYSTEM; IMMUNOMODULATION; LYMPH NODE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; VIRUS ENVELOPE; VIRUS INFECTIVITY; AMINO ACID SEQUENCE; COMPARATIVE STUDY; GENETIC RECOMBINATION; GENETICS; METABOLISM; MISSENSE MUTATION; MOLECULAR GENETICS; PHYSIOLOGY; PROTEIN BINDING; SEQUENCE ALIGNMENT; VIROLOGY; VIRUS ENTRY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIGENS, CD4; ENV GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; HIV-1; HUMANS; MACROPHAGES; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION, MISSENSE; PROTEIN BINDING; RECOMBINATION, GENETIC; SEQUENCE ALIGNMENT; VIRUS INTERNALIZATION;

EID: 62749141506     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.02133-08     Document Type: Article

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