The first study on the effects of microcystin-RR on gene expression profiles of antioxidant enzymes and heat shock protein-70 in Synechocystis sp. PCC6803

Toxicon

Volumn 53, Issue 6, 2009, Pages 595-601

  Li, Huiying ^a   Xie, Ping ^a   Zhang, Dawen ^a   Chen, Jun ^a  

^a INSTITUTE OF HYDROBIOLOGY   (China)

Author keywords

Antioxidant enzymes; Cell aggregation; Microcystin RR; mRNA expression; Synechocystis sp. PCC6803

Indexed keywords

ANTIOXIDANT; ENZYME; GAMMA TOCOPHEROL METHYLTRANSFERASE; GLUTATHIONE PEROXIDASE 1; HEAT SHOCK PROTEIN 70; IRON SUPEROXIDE DISMUTASE; KATG PROTEIN; MESSENGER RNA; MICROCYSTIN RR; PROTEIN DNAK; PROTEIN DNAK2; PROTEIN SODB; UNCLASSIFIED DRUG;

ALGAL GENETICS; ARTICLE; CELL AGGREGATION; CONCENTRATION RESPONSE; DRUG EFFECT; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION PROFILING; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SYNECHOCYSTIS;

ALGAE; ANIMALIA; CYANOBACTERIA; EMBRYOPHYTA; SYNECHOCYSTIS SP.;

EID: 62649150146     PISSN: 00410101     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.toxicon.2008.11.005     Document Type: Article

References (37)

1. Arrigo A.P. Small stress proteins: chaperones that act as regulators of intracellular redox state and programmed cell death. Biol. Chem. 379 1 (1998) 19-26
2. Bulera S.J., Eddy S.M., Ferguson E., Jatkoe T.A., Reindel J.F., Bleavins M.R., and De La Iglesia F.A. RNA expression in the early characterization of hepatotoxicants in Wistar rats by high-density DNA microarrays. Hepatology 33 5 (2001) 1239-1258
3. Collins M.D., and Jones D. Distribution of isoprenoid quinone structural types in bacteria and their taxonomic implications. Microbiol. Rev. 45 2 (1981) 316-354
4. Corrido C., Curbuxani S., Ravagnan L., and Kroemer G. Heat shock proteins: endogenous modulators of apoptotic cell death. Biochem. Biophys. Res. Commun. 286 3 (2001) 433-442
5. Currie R., and Tanguay R. Analysis of RNA for transcripts for catalase and SP71 in rat hearts after in vivo hyperthermia. Biochem. Cell Biol. 69 5-6 (1991) 375-382
6. Ding W.X., Shen H., and Ong C. Critical role of reactive oxygen species and mitochondrial permeability transition in microcystin induced rapid apoptosis in rat hepatocytes. Hepatology 32 3 (2000) 547-555
7. Eriksson J.E., Toivola D., Meriluoto J.A.O., Karaki H., Han Y., and Hartshorne D. Hepatocyte deformation induced by cyanobacterial toxins reflects inhibition of protein phosphatases. Biochem. Biophys. Res. Commun. 173 3 (1990) 1347-1353
8. Fastner J., Codd G.A., Metcalf J.S., Woitke P., Wiedner C., and Utkilen H. An international intercomparison exercise for the determination of purified microcystin-LR and microcystins in cyanobacterial field material. Anal. Bioanal. Chem. 374 3 (2002) 437-444
9. Fu J., and Xie P. The acute effects of microcystin LR on the transcription of nine glutathione S-transferase genes in common carp Cyprinus carpio L. Aquat. Toxicol. 80 3 (2006) 261-266
10. Gautier J.P., Holzhaeuser D., Markovic J., Germaud E., Schilter B., and Ad Turesky R.J. Oxidative damage and stress response from ochratoxin A exposure in rats. Free Radic. Biol. Med. 30 10 (2001) 1089-1098
11. Gehringer M.M., Shephard E.G., Downing T.G., Wiegand C., and Neilan B.A. An investigation into the detoxification of microcystin-LR by the glutathione pathway in BALB/C mice. Int. J. Biochem. Cell Biol. 36 5 (2004) 931-941
12. Halliwell B. Oxidants and human disease: some new concepts. FASEB J. 1 5 (1987) 358-364
13. Hihara Y., Kamei A., Kanehisa M., Kaplan A., and Ikeuchi M. DNA microarray analysis of cyanobacterial gene expression during acclimation to high light. Plant Cell 13 4 (2001) 793-806
14. Hu Z.Q., Liu Y.D., and Li D.H. Physiological and biochemical analyses of microcystin-RR toxicity on the cyanobacterium Synechococcus elongatus. Environ. Toxicol. 19 6 (2004) 571-577
15. Hu Z.Q., Liu Y.D., Li D.H., and Dauta A. Growth and antioxidant system of the cyanobacterium Synechococcus elongatus in response to microcystin-RR. Hydrobiologia 534 1 (2005) 23-29
16. Jakopitsch C., Ruker F., Regelsberger G., Dockal M., Peschek G.A., and Obinger C. Catalase-peroxidase from the cyanobacterium Synechocystis PCC 6803: cloning, overexpression in Escherichia coli, and kinetic characterization. Biol. Chem. 380 9 (1999) 1087-1096
17. Jayaraj R., Anand T., and Rao P.V. Activity and gene expression profile of certain antioxidant enzymes to microcystin-LR induced oxidative stress in mice. Toxicology 220 2-3 (2006) 136-146
18. Jones G.J., and Orr P.T. Release and degradation of microcystin following algicide treatment of a Microcystis aeruginosa bloom in a recreational lake, as determined by HPLC and protein phosphatase inhibition assay. Water Res. 28 4 (1994) 871-876
19. Kurmayer R., Christiansen G., and Chorus I. The abundance of microcystin-producing genotypes correlates positively with colony size in Microcystis sp. and determines its microcystin net production in Lake Wannsee. Appl. Environ. Microbiol. 69 2 (2003) 787-795
20. MacKintosh C., Beattie K.A., Klumpp S., Cohen P., and Codd G.A. Cyanobacterial microcystin-LR is a potent and specific inhibitor of protein phosphatases 1 and 2A from both mammals and higher plants. FEBS Lett. 264 2 (1990) 187-192
21. Maeda H., Sakuragi Y., Bryant D.A., and DellaPenna D. Tocopherols protect Synechocystis sp. strain PCC 6803 from lipid peroxidation. Plant Physiol. 138 3 (2005) 1422-1435
22. Mehlen P., Kretz-Remy C., Preville X., and Arrigo A. Human Hsp 27, Drosophila Hsp 27 and human alpha B crystallin expression-mediated increase in glutathione is essential for the protective activity of these proteins against TNFalpha-induced cell death. EMBO J. 15 11 (1996) 2695-2706
23. Munné-Bosch S. The role of alpha-tocopherol in plant stress tolerance. J. Plant Physiol. 162 7 (2005) 743-748
24. Paerl H.W., Fulton R.S., Moisander P.H., and Dyble J. Harmful freshwater algal blooms, with an emphasis on cyanobacteria. Sci. World J. 1 (2001) 76-113
25. Park H.D., and Lwami C. Temporal variabilities of the concentrations of intra- and extracellular microcystin and toxic Microcystis species in a hypereutrophic lake, Lake Suwa, Japan (1991-1994. Environ. Toxicol. Water Qual. 13 (1998) 61-72
26. Pflugmacher S. Promotion of oxidative stress in the aquatic macrophyte Ceratophyllum demersum during biotransformation of the cyanobacterial toxin microcystin-LR. Aquat. Toxicol. 70 3 (2004) 169-178
27. Rouault T.A., and Klausner R.D. Iron-sulfur clusters as biosensors of oxidants and iron. Trends Biochem. Sci. 21 5 (1996) 174-177
28. Sedmak B., and Elersek T. Microcystins induce morphological and physiological changes in selected representative phytoplanktons. Microb. Ecol. 50 2 (2005) 298-305
29. Singh D.P., Tyagi M.B., Kumar A., Thakur J.K., and Kumar A. Antialgal activity of a hepatotoxin-producing cyanobacterium, Microcystis aeruginosa. World J. Microbiol. Biotechnol. 17 1 (2001) 15-22
30. Suchy F.J. Hepatocellular transport of bile acids. Semin. Liver Dis. 13 3 (1993) 235-247
31. Ushimaru T., Nishiyama Y., Hayashi H., and Murata N. No coordinated transcriptional regulation of the sod-kat antioxidative system in Synechocystis sp. PCC6803. J. Plant Physiol. 159 7 (2002) 805-807
32. Vassilakaki M., and Pflugmacher S. Oxidative stress response of Synechocystis sp. (PCC6803) due to exposure to microcystin-LR and cell-free cyanobacterial crude extract containing microcystin-LR. J. Appl. Phycol. 20 3 (2008) 219-225
33. Wang L., Liang X.F., Liao W.Q., Lei L.M., and Han B.P. Structural and functional characterization of microcystin detoxification-related liver genes in a phytoplanktivorous fish, Nile tilapia (Oreochromis niloticus). Comp. Biochem. Physiol. C Toxicol. Pharmacol. 144 3 (2006) 216-227
34. Yin L.Y., Huang J.Q., Huang W.M., Li D.H., and Liu Y.D. Responses of antioxidant system in Arabidopsis thaliana suspension cells to the toxicity of microcystin-RR. Toxicon 46 8 (2005) 859-864
35. Yin L.Y., Huang J.Q., Huang W.M., Li D.H., Wang G.H., and Liu Y.D. Microcystin-RR-induced accumulation of reactive oxygen species and alteration of antioxidant systems in tobacco BY-2 cells. Toxicon 46 5 (2005) 507-512
36. Zhang D.W., Xie P., Liu Y.Q., Chen J., and Liang G.D. Bioaccumulation of the hepatotoxic microcystins in various organs of a freshwater snail from a subtropical Chinese lake, Taihu lake, with dense toxic Microcystis blooms. Environ. Toxicol. Chem. 26 1 (2007) 171-176
37. Žegura B., Zajc I., Lah T.T., and Filipič M. Patterns of microcystin-LR induced alteration of the expression of genes involved in response to DNA damage and apoptosis. Toxicon 51 4 (2008) 615-623