-
2
-
-
0030734345
-
Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells
-
Cong L.N., Chen H., Li Y., Zhon L., McGibbon M.A., Taylor S.I., and Quon M.J. Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. Mol. Endocrinol. 11 (1997) 1881-1890
-
(1997)
Mol. Endocrinol.
, vol.11
, pp. 1881-1890
-
-
Cong, L.N.1
Chen, H.2
Li, Y.3
Zhon, L.4
McGibbon, M.A.5
Taylor, S.I.6
Quon, M.J.7
-
3
-
-
0036797873
-
Regulation of insulin signal transduction pathway by a small-molecule insulin receptor activator
-
Ding V.D.H., Qureshi S.A., Szalkowski D., Li Z., Biazzo-Ashnault D.E., Xie D., Liu K., Jones A.B., Moller D.E., and Zhang B.B. Regulation of insulin signal transduction pathway by a small-molecule insulin receptor activator. Biochem. J. 367 (2002) 301-306
-
(2002)
Biochem. J.
, vol.367
, pp. 301-306
-
-
Ding, V.D.H.1
Qureshi, S.A.2
Szalkowski, D.3
Li, Z.4
Biazzo-Ashnault, D.E.5
Xie, D.6
Liu, K.7
Jones, A.B.8
Moller, D.E.9
Zhang, B.B.10
-
4
-
-
0026526138
-
123I-labeled insulin and scintigraphic scanning in severe insulin resistance
-
123I-labeled insulin and scintigraphic scanning in severe insulin resistance. Diabetes Care 15 (1992) 651-656
-
(1992)
Diabetes Care
, vol.15
, pp. 651-656
-
-
Dozio, N.1
Micossi, P.2
Galimberti, G.3
Sartori, S.4
Pozza, G.5
Dosio, F.6
Savi, A.7
Gerundini, P.G.8
Fazio, F.9
Chiumello, G.10
-
5
-
-
0025874250
-
Evidence supporting a passive role for the insulin receptor transmembrane domain in insulin-dependent signal transduction
-
Frattali A.L., Treadway J.L., and Pessin J.E. Evidence supporting a passive role for the insulin receptor transmembrane domain in insulin-dependent signal transduction. J. Biol. Chem. 266 (1991) 9829-9834
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 9829-9834
-
-
Frattali, A.L.1
Treadway, J.L.2
Pessin, J.E.3
-
6
-
-
0023392635
-
The insulin receptor: molecular biology and transmembrane signaling
-
Goldfine I.D. The insulin receptor: molecular biology and transmembrane signaling. Endocrin. Rev. 8 (1987) 235-255
-
(1987)
Endocrin. Rev.
, vol.8
, pp. 235-255
-
-
Goldfine, I.D.1
-
7
-
-
0033180116
-
Unraveling the riddle of insulin resistance
-
Goldfine I.D. Unraveling the riddle of insulin resistance. J. Lab. Clin. Med. 134 (1999) 100-102
-
(1999)
J. Lab. Clin. Med.
, vol.134
, pp. 100-102
-
-
Goldfine, I.D.1
-
8
-
-
0028903232
-
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips for obese subjects
-
Goodyear L.J., Giorgino F., Sherman L.A., Carey J., Smith R.J., and Dohm G.L. Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips for obese subjects. J. Clin. Inv. 95 (1995) 2195-2204
-
(1995)
J. Clin. Inv.
, vol.95
, pp. 2195-2204
-
-
Goodyear, L.J.1
Giorgino, F.2
Sherman, L.A.3
Carey, J.4
Smith, R.J.5
Dohm, G.L.6
-
9
-
-
0031782480
-
Constitutive activation of protein kinase Bα by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells
-
Hajduch E., Alessi D.R., Hemmings B.A., and Hundal H.S. Constitutive activation of protein kinase Bα by membrane targeting promotes glucose and system A amino acid transport, protein synthesis, and inactivation of glycogen synthase kinase 3 in L6 muscle cells. Diabetes 47 (1998) 1006-1019
-
(1998)
Diabetes
, vol.47
, pp. 1006-1019
-
-
Hajduch, E.1
Alessi, D.R.2
Hemmings, B.A.3
Hundal, H.S.4
-
10
-
-
34247115917
-
Insulin-mimetic and insulin-sensitizing activities of a pentacyclic triterpenoid insulin receptor activator
-
Jung S.H., Ha Y.J., Shim E.K., Choi S.Y., Jin J.L., Yun-Choi H.S., and Lee J.R. Insulin-mimetic and insulin-sensitizing activities of a pentacyclic triterpenoid insulin receptor activator. Biochem. J. 403 (2007) 243-250
-
(2007)
Biochem. J.
, vol.403
, pp. 243-250
-
-
Jung, S.H.1
Ha, Y.J.2
Shim, E.K.3
Choi, S.Y.4
Jin, J.L.5
Yun-Choi, H.S.6
Lee, J.R.7
-
11
-
-
0027953703
-
Banting lecture: insulin action, diabetogenes, and the cause of type II diabetes
-
Kahn C.R. Banting lecture: insulin action, diabetogenes, and the cause of type II diabetes. Diabetes 43 (1994) 1066-1084
-
(1994)
Diabetes
, vol.43
, pp. 1066-1084
-
-
Kahn, C.R.1
-
12
-
-
33645564707
-
Induction of cytochrome P450-dependent monooxygenase by extracts of the medicinal herb Salvia miltiorrhiza
-
Kuo Y.H., Lin Y.L., Don M.J., Chen R.M., and Ueng Y.F. Induction of cytochrome P450-dependent monooxygenase by extracts of the medicinal herb Salvia miltiorrhiza. J. Pharm. Pharmcol. 58 (2006) 521-527
-
(2006)
J. Pharm. Pharmcol.
, vol.58
, pp. 521-527
-
-
Kuo, Y.H.1
Lin, Y.L.2
Don, M.J.3
Chen, R.M.4
Ueng, Y.F.5
-
13
-
-
0035081517
-
A novel small molecule that directly sensitizes the insulin receptor in vitro and in vivo
-
Manchem V.P., Goldfine I.D., Kohanski R.A., Cristobal C.P., Lum R.T., Schow S.R., Shi S., Spevak W.R., Laborde E., Toavs D.K., Villar H.O., Wick M.M., and Kozlowski M.R. A novel small molecule that directly sensitizes the insulin receptor in vitro and in vivo. Diabetes 50 (2001) 824-830
-
(2001)
Diabetes
, vol.50
, pp. 824-830
-
-
Manchem, V.P.1
Goldfine, I.D.2
Kohanski, R.A.3
Cristobal, C.P.4
Lum, R.T.5
Schow, S.R.6
Shi, S.7
Spevak, W.R.8
Laborde, E.9
Toavs, D.K.10
Villar, H.O.11
Wick, M.M.12
Kozlowski, M.R.13
-
14
-
-
0025945012
-
Insulin resistance - mechanisms, syndromes, and implications
-
Moller D.E., and Flier J.S. Insulin resistance - mechanisms, syndromes, and implications. New Eng. J. Med. 325 (1991) 938-948
-
(1991)
New Eng. J. Med.
, vol.325
, pp. 938-948
-
-
Moller, D.E.1
Flier, J.S.2
-
15
-
-
0037113863
-
Regulation of insulin receptor function by a small molecule insulin receptor activator
-
Pender C., Goldfine I.R., Manchem V.P., Evans J.L., Spevak W.R., Shi S., Rao S., Bajjalieh S., Maddux B.A., and Youngren J.F. Regulation of insulin receptor function by a small molecule insulin receptor activator. J. Biol. Chem. 277 (2002) 43565-43571
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 43565-43571
-
-
Pender, C.1
Goldfine, I.R.2
Manchem, V.P.3
Evans, J.L.4
Spevak, W.R.5
Shi, S.6
Rao, S.7
Bajjalieh, S.8
Maddux, B.A.9
Youngren, J.F.10
-
16
-
-
0033913213
-
Signaling pathways in insulin action: molecular target of insulin resistance
-
Pessin J.E., and Saltiel A.R. Signaling pathways in insulin action: molecular target of insulin resistance. J. Clin. Inv. 106 (2000) 165-169
-
(2000)
J. Clin. Inv.
, vol.106
, pp. 165-169
-
-
Pessin, J.E.1
Saltiel, A.R.2
-
17
-
-
0031058699
-
Two novel abietane diterpenes from Salvia miltiorrhiza
-
Ryu S.Y., No Z., Kim S.H., and Ahn J.W. Two novel abietane diterpenes from Salvia miltiorrhiza. Planta Med. 63 (1997) 44-46
-
(1997)
Planta Med.
, vol.63
, pp. 44-46
-
-
Ryu, S.Y.1
No, Z.2
Kim, S.H.3
Ahn, J.W.4
-
18
-
-
0035787076
-
Discovery of a small molecule insulin receptor activator
-
Salituro G.M., Pelaez F., and Zhang B.B. Discovery of a small molecule insulin receptor activator. Rec. Prog. Hor. Res. 56 (2001) 107-126
-
(2001)
Rec. Prog. Hor. Res.
, vol.56
, pp. 107-126
-
-
Salituro, G.M.1
Pelaez, F.2
Zhang, B.B.3
-
19
-
-
0032143284
-
Phosphoinositide 3-kinase: the key switch mechanism in insulin signaling
-
Shepherd P.R., Withers D.J., and Siddle K. Phosphoinositide 3-kinase: the key switch mechanism in insulin signaling. Biochem. J. 333 (1998) 471-490
-
(1998)
Biochem. J.
, vol.333
, pp. 471-490
-
-
Shepherd, P.R.1
Withers, D.J.2
Siddle, K.3
-
20
-
-
0033515429
-
Deconstructing type 2 diabetes
-
Taylor S.I. Deconstructing type 2 diabetes. Cell 97 (1999) 9-12
-
(1999)
Cell
, vol.97
, pp. 9-12
-
-
Taylor, S.I.1
-
21
-
-
0025115342
-
Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects
-
Thies R.S., Molina J.M., Ciaraldi T.P., Freidenberg G.R., and Olefsky J.M. Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects. Diabetes 39 (1990) 250-259
-
(1990)
Diabetes
, vol.39
, pp. 250-259
-
-
Thies, R.S.1
Molina, J.M.2
Ciaraldi, T.P.3
Freidenberg, G.R.4
Olefsky, J.M.5
-
22
-
-
33845768814
-
New developments in the chemistry and biology of the bioactive constituents of Tanshen
-
Wang X., Morris-Natschke S.L., and Lee K.-H. New developments in the chemistry and biology of the bioactive constituents of Tanshen. Med. Res. Rev. 27 (2007) 133-148
-
(2007)
Med. Res. Rev.
, vol.27
, pp. 133-148
-
-
Wang, X.1
Morris-Natschke, S.L.2
Lee, K.-H.3
-
23
-
-
0033049422
-
Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts
-
Wang Q., Somwar R., Bilan P.J., Liu Z., Jin J., Woodgett J.R., and Klip A. Protein kinase B/Akt participates in GLUT4 translocation by insulin in L6 myoblasts. Mol. Cell. Biol. 19 (1999) 4008-4018
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 4008-4018
-
-
Wang, Q.1
Somwar, R.2
Bilan, P.J.3
Liu, Z.4
Jin, J.5
Woodgett, J.R.6
Klip, A.7
-
24
-
-
0028092130
-
Effects of tanshinone VI derivatives on post-hypoxic contractile dysfunction of perfused rat hearts
-
Yagi A., Okamura N., Tanonaka K., and Takeo S. Effects of tanshinone VI derivatives on post-hypoxic contractile dysfunction of perfused rat hearts. Planta Med. 60 (1994) 405-409
-
(1994)
Planta Med.
, vol.60
, pp. 405-409
-
-
Yagi, A.1
Okamura, N.2
Tanonaka, K.3
Takeo, S.4
-
25
-
-
21244483796
-
Tanshinone IIA isolated from Salvia miltiorrhiza elicits the cell death of human endothelial cells
-
Yang L.-J., Jeng C.-J., Kung H.-N., Chang C.-C., Wang A.-G., Chau G.-Y., Don M.-J., and Chau Y.-P. Tanshinone IIA isolated from Salvia miltiorrhiza elicits the cell death of human endothelial cells. J. Biomed. Sci. 12 (2005) 347-361
-
(2005)
J. Biomed. Sci.
, vol.12
, pp. 347-361
-
-
Yang, L.-J.1
Jeng, C.-J.2
Kung, H.-N.3
Chang, C.-C.4
Wang, A.-G.5
Chau, G.-Y.6
Don, M.-J.7
Chau, Y.-P.8
-
26
-
-
0033532347
-
Discovery of a small molecule insulin mimetic with antidiabetic activity in mice
-
Zhang B.B., Salituro G., Szalkowski D., Li Z.H., Zhang Y., Royo I., Vilella D., Diez M.T., Pelaez F., Ruby C., Kendall R.L., Mao X., Griffin P., Calaycay J., Zierath J.R., Heck J.V., Smith R.G., and Moller D.E. Discovery of a small molecule insulin mimetic with antidiabetic activity in mice. Science (Washington, DC) 284 (1999) 974-977
-
(1999)
Science (Washington, DC)
, vol.284
, pp. 974-977
-
-
Zhang, B.B.1
Salituro, G.2
Szalkowski, D.3
Li, Z.H.4
Zhang, Y.5
Royo, I.6
Vilella, D.7
Diez, M.T.8
Pelaez, F.9
Ruby, C.10
Kendall, R.L.11
Mao, X.12
Griffin, P.13
Calaycay, J.14
Zierath, J.R.15
Heck, J.V.16
Smith, R.G.17
Moller, D.E.18
-
27
-
-
0033866831
-
New approaches in the treatment of type 2 diabetes
-
Zhang B.B., and Moller D.E. New approaches in the treatment of type 2 diabetes. Curr. Opin. Chem. Biol. 4 (2000) 461-467
-
(2000)
Curr. Opin. Chem. Biol.
, vol.4
, pp. 461-467
-
-
Zhang, B.B.1
Moller, D.E.2
-
28
-
-
45849106891
-
Determination of tanshinones in Salvia miltiorrhiza Bunge by high-performance liquid chromatography with a coulometric electrode array system
-
Zheng X., Ma L., Zhang H., and Gan Y. Determination of tanshinones in Salvia miltiorrhiza Bunge by high-performance liquid chromatography with a coulometric electrode array system. Anal. Lett. 41 (2008) 1047-1058
-
(2008)
Anal. Lett.
, vol.41
, pp. 1047-1058
-
-
Zheng, X.1
Ma, L.2
Zhang, H.3
Gan, Y.4
-
29
-
-
27844511101
-
Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use
-
Zhou L., Zuo Z., and Chow M.S.S. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J. Clin. Pharmacol. 45 (2005) 1345-1359
-
(2005)
J. Clin. Pharmacol.
, vol.45
, pp. 1345-1359
-
-
Zhou, L.1
Zuo, Z.2
Chow, M.S.S.3
|