메뉴 건너뛰기




Volumn 11, Issue 2, 2009, Pages 143-149

The role of statins in the treatment of the metabolic syndrome

Author keywords

[No Author keywords available]

Indexed keywords

ATORVASTATIN; FENOFIBRATE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; PRAVASTATIN;

EID: 62549153138     PISSN: 15226417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11906-009-0025-6     Document Type: Review
Times cited : (16)

References (51)
  • 1
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven GM: Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988, 37:1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 2
    • 0031851293 scopus 로고    scopus 로고
    • Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a who consultation
    • Alberti KG, Zimmet PZ: Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus provisional report of a who consultation. Diabet Med 1998, 15:539-553.
    • (1998) Diabet Med , vol.15 , pp. 539-553
    • Alberti, K.G.1    Zimmet, P.Z.2
  • 3
    • 0035897696 scopus 로고    scopus 로고
    • Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III)
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
    • Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults: Executive summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001, 285:2486-2497.
    • (2001) JAMA , vol.285 , pp. 2486-2497
  • 4
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome - A new worldwide definition
    • Alberti KG, Zimmet P, Shaw J: The metabolic syndrome - a new worldwide definition. Lancet 2005, 366:1059-1062.
    • (2005) Lancet , vol.366 , pp. 1059-1062
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 6
    • 30944451953 scopus 로고    scopus 로고
    • Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus
    • Wilson PW, D'Agostino RB, Parise H, et al.: Metabolic syndrome as a precursor of cardiovascular disease and type 2 diabetes mellitus. Circulation 2005, 112:3066-3072.
    • (2005) Circulation , vol.112 , pp. 3066-3072
    • Wilson, P.W.1    D'Agostino, R.B.2    Parise, H.3
  • 7
    • 33846365989 scopus 로고    scopus 로고
    • Metabolic syndrome and risk of incident cardiovascular events and death: A systematic review and meta-analysis of longitudinal studies
    • Gami AS, Witt BJ, Howard DE, et al.: Metabolic syndrome and risk of incident cardiovascular events and death: A systematic review and meta-analysis of longitudinal studies. J Am Coll Cardiol 2007, 49:403-414.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 403-414
    • Gami, A.S.1    Witt, B.J.2    Howard, D.E.3
  • 8
    • 27444443876 scopus 로고    scopus 로고
    • Diagnosis and management of the metabolic syndrome: An American heart association/national heart, lung, and blood institute scientific statement
    • Grundy SM, Cleeman JI, Daniels SR, et al.: Diagnosis and management of the metabolic syndrome: An American heart association/national heart, lung, and blood institute scientific statement. Circulation 2005, 112:2735-2752.
    • (2005) Circulation , vol.112 , pp. 2735-2752
    • Grundy, S.M.1    Cleeman, J.I.2    Daniels, S.R.3
  • 9
    • 33846970555 scopus 로고    scopus 로고
    • Metabolic syndrome: A multiplex cardiovascular risk factor
    • Grundy SM: MetAbolic syndrome: a multiplex cardiovascular risk factor. J Clin Endocrinol Metab 2007, 92:399-404.
    • (2007) J Clin Endocrinol Metab , vol.92 , pp. 399-404
    • Grundy, S.M.1
  • 10
    • 33746355566 scopus 로고    scopus 로고
    • Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy
    • Cannon CP, Steinberg BA, Murphy SA, et al.: Meta-analysis of cardiovascular outcomes trials comparing intensive versus moderate statin therapy. J Am Coll Cardiol 2006, 48:438-445.
    • (2006) J Am Coll Cardiol , vol.48 , pp. 438-445
    • Cannon, C.P.1    Steinberg, B.A.2    Murphy, S.A.3
  • 11
    • 3142729178 scopus 로고    scopus 로고
    • Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines
    • Grundy SM, Cleeman JI, Merz CN, et al.: Implications of recent clinical trials for the National Cholesterol Education Program Adult Treatment Panel III guidelines. Circulation 2004, 110:227-239.
    • (2004) Circulation , vol.110 , pp. 227-239
    • Grundy, S.M.1    Cleeman, J.I.2    Merz, C.N.3
  • 12
    • 29044441589 scopus 로고    scopus 로고
    • Implications from the Air Force/Texas Coronary Atherosclerosis Prevention Study for the Adult Treatment Panel III guidelines
    • Clearfield M, Downs JR, Lee M, et al.: Implications from the Air Force/ Texas Coronary Atherosclerosis Prevention Study for the Adult Treatment Panel III guidelines. Am J Cardiol 2005, 96:1674-1680.
    • (2005) Am J Cardiol , vol.96 , pp. 1674-1680
    • Clearfield, M.1    Downs, J.R.2    Lee, M.3
  • 13
    • 0042665536 scopus 로고    scopus 로고
    • Metabolic syndrome with and without c-reactive protein as a predictor of coronary heart disease and diabetes in the west of Scotland coronary prevention study
    • Sattar N, Gaw A, Scherbakova O, et al.: Metabolic syndrome with and without c-reactive protein as a predictor of coronary heart disease and diabetes in the west of Scotland coronary prevention study. Circulation 2003, 108:414-419.
    • (2003) Circulation , vol.108 , pp. 414-419
    • Sattar, N.1    Gaw, A.2    Scherbakova, O.3
  • 14
    • 3042755369 scopus 로고    scopus 로고
    • Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: Subgroup analyses of the Scandinavian simvastatin survival study (4s)
    • Pyorala K, Ballantyne CM, Gumbiner B, et al.: Reduction of cardiovascular events by simvastatin in nondiabetic coronary heart disease patients with and without the metabolic syndrome: Subgroup analyses of the Scandinavian simvastatin survival study (4s). Diabetes Care 2004, 27:1735-1740.
    • (2004) Diabetes Care , vol.27 , pp. 1735-1740
    • Pyorala, K.1    Ballantyne, C.M.2    Gumbiner, B.3
  • 15
    • 33748303084 scopus 로고    scopus 로고
    • Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: Analysis of the treating to new targets study
    • Deedwania P, Barter P, Carmena R, et al.: Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: Analysis of the treating to new targets study. Lancet 2006, 368:919-928.
    • (2006) Lancet , vol.368 , pp. 919-928
    • Deedwania, P.1    Barter, P.2    Carmena, R.3
  • 16
    • 0037083163 scopus 로고    scopus 로고
    • Effects of atorvastatin on oxidized low-density lipoprotein, lowdensity lipoprotein subfraction distribution, and remnant lipoprotein in patients with mixed hyperlipoproteinemia
    • Sasaki S, Kuwahara N, Kunitomo K, et al.: Effects of atorvastatin on oxidized low-density lipoprotein, lowdensity lipoprotein subfraction distribution, and remnant lipoprotein in patients with mixed hyperlipoproteinemia. Am J Cardiol 2002, 89:386-389.
    • (2002) Am J Cardiol , vol.89 , pp. 386-389
    • Sasaki, S.1    Kuwahara, N.2    Kunitomo, K.3
  • 17
    • 0035572718 scopus 로고    scopus 로고
    • Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors
    • Takemoto M, Liao JK: Pleiotropic effects of 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitors. Arterioscler Thromb Vasc Biol 2001, 21:1712-1719.
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 1712-1719
    • Takemoto, M.1    Liao, J.K.2
  • 18
    • 0033552883 scopus 로고    scopus 로고
    • Atherosclerosis - An inflammatory disease
    • Ross R: Atherosclerosis - an inflammatory disease. N Engl J Med 1999, 340:115-126.
    • (1999) N Engl J Med , vol.340 , pp. 115-126
    • Ross, R.1
  • 19
    • 0037078969 scopus 로고    scopus 로고
    • Comparison of c-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events
    • Ridker PM, Rifai N, Rose L, et al.: Comparison of c-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. N Engl J Med 2002, 347:1557-1565.
    • (2002) N Engl J Med , vol.347 , pp. 1557-1565
    • Ridker, P.M.1    Rifai, N.2    Rose, L.3
  • 20
    • 6944237757 scopus 로고    scopus 로고
    • Adipokines: Inflammation and the pleiotropic role of white adipose tissue
    • TrayhuIn P, Wood IS: Adipokines: inflammation and the pleiotropic role of white adipose tissue. Br J Nutr 2004, 92:347-355.
    • (2004) Br J Nutr , vol.92 , pp. 347-355
    • Trayhurn, P.1    Wood, I.S.2
  • 21
    • 0348230958 scopus 로고    scopus 로고
    • Obesity is associated with macrophage accumulation in adipose tissue
    • Weisberg SP, McCann D, Desai M, et al.: Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 2003, 112:1796-1808.
    • (2003) J Clin Invest , vol.112 , pp. 1796-1808
    • Weisberg, S.P.1    McCann, D.2    Desai, M.3
  • 22
    • 36049004221 scopus 로고    scopus 로고
    • Inflamed adipose tissue: A culprit underlying the metabolic syndrome and atherosclerosis
    • Gustafson B, Hammarstedt A, Andersson CX, Smith U: Inflamed adipose tissue: A culprit underlying the metabolic syndrome and atherosclerosis. Arterioscler Thromb Vasc Biol 2007, 27:2276-2283.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2276-2283
    • Gustafson, B.1    Hammarstedt, A.2    Andersson, C.X.3    Smith, U.4
  • 23
    • 31344443020 scopus 로고    scopus 로고
    • Justification for the use of statins in primary prevention: An intervention trial evaluating rosuvastatin (JUPITER)-can c-reactive protein be used to target statin therapy in primary prevention?
    • Mora S, Ridker PM: Justification for the use of statins in primary prevention: An intervention trial evaluating rosuvastatin (JUPITER)-can c-reactive protein be used to target statin therapy in primary prevention? Am J Cardiol 2006, 97:33A-41A.
    • (2006) Am J Cardiol , vol.97
    • Mora, S.1    Ridker, P.M.2
  • 24
    • 2942670689 scopus 로고    scopus 로고
    • Should c-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk?
    • Ridker PM, Wilson PW, Grundy SM: Should c-reactive protein be added to metabolic syndrome and to assessment of global cardiovascular risk? Circulation 2004, 109:2818-2825.
    • (2004) Circulation , vol.109 , pp. 2818-2825
    • Ridker, P.M.1    Wilson, P.W.2    Grundy, S.M.3
  • 25
    • 33751519338 scopus 로고    scopus 로고
    • Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome
    • Devaraj S, Chan E, Jialal I: Direct demonstration of an antiinflammatory effect of simvastatin in subjects with the metabolic syndrome. J Clin Endocrinol Metab 2006, 91:4489-4496.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 4489-4496
    • Devaraj, S.1    Chan, E.2    Jialal, I.3
  • 26
    • 51749103102 scopus 로고    scopus 로고
    • Comparison effect of atorvastatin (10 versus 80 mg) on biomarkers of inflammation and oxidative stress in subjects with metabolic syndrome
    • Singh U, Devaraj S, Jialal I, Siegel D: Comparison effect of atorvastatin (10 versus 80 mg) on biomarkers of inflammation and oxidative stress in subjects with metabolic syndrome. Am J Cardiol 2008, 102:321-325.
    • (2008) Am J Cardiol , vol.102 , pp. 321-325
    • Singh, U.1    Devaraj, S.2    Jialal, I.3    Siegel, D.4
  • 27
    • 0142119459 scopus 로고    scopus 로고
    • Effects of statins on nonlipid serum markers associated with cardiovascular disease: A systematic review
    • Balk EM, Lau J, Goudas LC, et al.: Effects of statins on nonlipid serum markers associated with cardiovascular disease: A systematic review. Ann Intern Med 2003, 139:670-682.
    • (2003) Ann Intern Med , vol.139 , pp. 670-682
    • Balk, E.M.1    Lau, J.2    Goudas, L.C.3
  • 28
    • 34248342266 scopus 로고    scopus 로고
    • Low-density lipoprotein-dependent and - Independent effects of cholesterol-lowering therapies on c-reactive protein: A meta-analysis
    • Kinlay S: Low-density lipoprotein-dependent and - independent effects of cholesterol-lowering therapies on c-reactive protein: A meta-analysis. J Am Coll Cardiol 2007, 49:2003-2009.
    • (2007) J Am Coll Cardiol , vol.49 , pp. 2003-2009
    • Kinlay, S.1
  • 29
    • 0025334367 scopus 로고
    • Regulatory functions of the vascular endothelium
    • Vane JR, Anggard EE, Botting RM: Regulatory functions of the vascular endothelium. N Engl J Med 1990, 323:27-36.
    • (1990) N Engl J Med , vol.323 , pp. 27-36
    • Vane, J.R.1    Anggard, E.E.2    Botting, R.M.3
  • 30
    • 0035018871 scopus 로고    scopus 로고
    • Cellular regulation of endothelial nitric oxide synthase
    • Govers R, Rabelink TJ: Cellular regulation of endothelial nitric oxide synthase. Am J Physiol Renal Physiol 2001, 280:F193-206.
    • (2001) Am J Physiol Renal Physiol , vol.280
    • Govers, R.1    Rabelink, T.J.2
  • 31
    • 0024536929 scopus 로고
    • Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease
    • Werns SW, Walton JA, Hsia HH, et al.: Evidence of endothelial dysfunction in angiographically normal coronary arteries of patients with coronary artery disease. Circulation 1989, 79:287-291.
    • (1989) Circulation , vol.79 , pp. 287-291
    • Werns, S.W.1    Walton, J.A.2    Hsia, H.H.3
  • 32
    • 28244466397 scopus 로고    scopus 로고
    • Inflammatory markers and the metabolic syndrome: Insights from therapeutic interventions
    • Koh KK, Han SH, Quon MJ: Inflammatory markers and the metabolic syndrome: Insights from therapeutic interventions. J Am Coll Cardiol 2005, 46:1978-1985.
    • (2005) J Am Coll Cardiol , vol.46 , pp. 1978-1985
    • Koh, K.K.1    Han, S.H.2    Quon, M.J.3
  • 34
    • 0032555170 scopus 로고    scopus 로고
    • Increased bioavailability of nitric oxide after lipid-lowering therapy in hypercholesterolemic patients: A randomized, placebo-controlled, double-blind study
    • John S, Schlaich M, Langenfeld M, et al.: Increased bioavailability of nitric oxide after lipid-lowering therapy in hypercholesterolemic patients: A randomized, placebo-controlled, double-blind study. Circulation 1998, 98:211-216.
    • (1998) Circulation , vol.98 , pp. 211-216
    • John, S.1    Schlaich, M.2    Langenfeld, M.3
  • 35
    • 0033817532 scopus 로고    scopus 로고
    • Effects of atorvastatin and vitamin C on endothelial function of hypercholesterolemic patients
    • Perticone F, Ceravolo R, Maio R, et al.: Effects of atorvastatin and vitamin C on endothelial function of hypercholesterolemic patients. Atherosclerosis 2000, 152:511-518.
    • (2000) Atherosclerosis , vol.152 , pp. 511-518
    • Perticone, F.1    Ceravolo, R.2    Maio, R.3
  • 36
    • 17844408136 scopus 로고    scopus 로고
    • Lipid-independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients
    • John S, Schneider MP, Delles C, et al.: Lipid-independent effects of statins on endothelial function and bioavailability of nitric oxide in hypercholesterolemic patients. Am Heart J 2005, 149:473.
    • (2005) Am Heart J , vol.149 , pp. 473
    • John, S.1    Schneider, M.P.2    Delles, C.3
  • 37
    • 38349120435 scopus 로고    scopus 로고
    • Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia
    • Ott C, Schlaich MP, Schmidt BM, et al.: Rosuvastatin improves basal nitric oxide activity of the renal vasculature in patients with hypercholesterolemia. Atherosclerosis 2008, 196:704-711.
    • (2008) Atherosclerosis , vol.196 , pp. 704-711
    • Ott, C.1    Schlaich, M.P.2    Schmidt, B.M.3
  • 38
    • 49449118649 scopus 로고    scopus 로고
    • Short term fluvastatin treatment lowers serum asymmetric dimethylarginine levels in patients with metabolic syndrome
    • Oguz A, Uzunlulu M: Short term fluvastatin treatment lowers serum asymmetric dimethylarginine levels in patients with metabolic syndrome. Int Heart J 2008, 49:303-311.
    • (2008) Int Heart J , vol.49 , pp. 303-311
    • Oguz, A.1    Uzunlulu, M.2
  • 39
    • 0032869042 scopus 로고    scopus 로고
    • Assessment and treatment of endothelial dysfunction in humans
    • Anderson TJ: Assessment and treatment of endothelial dysfunction in humans. J Am Coll Cardiol 1999, 34:631-638.
    • (1999) J Am Coll Cardiol , vol.34 , pp. 631-638
    • Anderson, T.J.1
  • 40
    • 0742266631 scopus 로고    scopus 로고
    • The metabolic syndrome and chronic kidney disease in US adults
    • Chen J, Muntner P, Hamm LL, et al.: The metabolic syndrome and chronic kidney disease in US adults. Ann Intern Med 2004, 140:167-174.
    • (2004) Ann Intern Med , vol.140 , pp. 167-174
    • Chen, J.1    Muntner, P.2    Hamm, L.L.3
  • 41
    • 33846023704 scopus 로고    scopus 로고
    • Effect of statin treatment on renal function and serum uric acid levels and their relation to vascular events in patients with coronary heart disease and metabolic syndrome: A subgroup analysis of the Greek atorvastatin and coronary heart disease evaluation (GREACE) study
    • Athyros VG, Mikhailidis DP, Liberopoulos EN, et al.: Effect of statin treatment on renal function and serum uric acid levels and their relation to vascular events in patients with coronary heart disease and metabolic syndrome: A subgroup analysis of the Greek atorvastatin and coronary heart disease evaluation (GREACE) study. Nephrol Dial Transplant 2007, 22:118-127.
    • (2007) Nephrol Dial Transplant , vol.22 , pp. 118-127
    • Athyros, V.G.1    Mikhailidis, D.P.2    Liberopoulos, E.N.3
  • 42
    • 26444447495 scopus 로고    scopus 로고
    • Impact of statins in microalbuminuric subjects with the metabolic syndrome: A substudy of the prevend intervention trial
    • Geluk CA, Asselbergs FW, Hillege HL, et al.: Impact of statins in microalbuminuric subjects with the metabolic syndrome: A substudy of the prevend intervention trial. Eur Heart J 2005, 26:1314-1320.
    • (2005) Eur Heart J , vol.26 , pp. 1314-1320
    • Geluk, C.A.1    Asselbergs, F.W.2    Hillege, H.L.3
  • 43
    • 16644367070 scopus 로고    scopus 로고
    • Albuminuria, not only a cardiovascular/renal risk marker, but also a target for treatment?
    • de Zeeuw D: Albuminuria, not only a cardiovascular/renal risk marker, but also a target for treatment? Kidney Int Suppl 2004:S2-S6.
    • (2004) Kidney Int Suppl
    • de Zeeuw, D.1
  • 44
    • 0036788492 scopus 로고    scopus 로고
    • Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population
    • Hillege HL, Fidler V, Diercks GF, et al.: Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation 2002, 106:1777-1782.
    • (2002) Circulation , vol.106 , pp. 1777-1782
    • Hillege, H.L.1    Fidler, V.2    Diercks, G.F.3
  • 45
    • 0038644536 scopus 로고    scopus 로고
    • Nonalcoholic steatohepatitis: Summary of an AASLD single topic conference
    • Neuschwander-Tetri BA, Caldwell SH: Nonalcoholic steatohepatitis: summary of an AASLD single topic conference. Hepatology 2003, 37:1202-1219.
    • (2003) Hepatology , vol.37 , pp. 1202-1219
    • Neuschwander-Tetri, B.A.1    Caldwell, S.H.2
  • 46
    • 28044446543 scopus 로고    scopus 로고
    • The metabolic syndrome as a predictor of nonalcoholic fatty liver disease
    • Hamaguchi M, Kojima T, Takeda N, et al.: The metabolic syndrome as a predictor of nonalcoholic fatty liver disease. Ann Intern Med 2005, 143:722-728.
    • (2005) Ann Intern Med , vol.143 , pp. 722-728
    • Hamaguchi, M.1    Kojima, T.2    Takeda, N.3
  • 47
    • 33745046866 scopus 로고    scopus 로고
    • Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: A randomised study
    • Athyros VG, Mikhailidis DP, Didangelos TP, et al.: Effect of multifactorial treatment on non-alcoholic fatty liver disease in metabolic syndrome: A randomised study. Curr Med Res Opin 2006, 22:873-883.
    • (2006) Curr Med Res Opin , vol.22 , pp. 873-883
    • Athyros, V.G.1    Mikhailidis, D.P.2    Didangelos, T.P.3
  • 48
    • 49649106710 scopus 로고    scopus 로고
    • Statins in liver disease: A molehill, an iceberg, or neither?
    • Argo CK, Loria P, CaAdwell SH, Lonardo A: Statins in liver disease: a molehill, an iceberg, or neither? Hepatology 2008, 48:662-669.
    • (2008) Hepatology , vol.48 , pp. 662-669
    • Argo, C.K.1    Loria, P.2    Caldwell, S.H.3    Lonardo, A.4
  • 49
    • 36348987648 scopus 로고    scopus 로고
    • Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial
    • Lewis JH, Mortensen ME, Zweig S, et al.: Efficacy and safety of high-dose pravastatin in hypercholesterolemic patients with well-compensated chronic liver disease: Results of a prospective, randomized, double-blind, placebo-controlled, multicenter trial. Hepatology 2007, 46:1453-1463.
    • (2007) Hepatology , vol.46 , pp. 1453-1463
    • Lewis, J.H.1    Mortensen, M.E.2    Zweig, S.3
  • 50
    • 34249342305 scopus 로고    scopus 로고
    • Statins in non-alcoholic fatty liver disease and chronically elevated liver enzymes: A histopathological follow-up study
    • Ekstedt M, Franzen LE, Mathiesen UL, et al.: Statins in non-alcoholic fatty liver disease and chronically elevated liver enzymes: A histopathological follow-up study. J Hepatol 2007, 47:135-141.
    • (2007) J Hepatol , vol.47 , pp. 135-141
    • Ekstedt, M.1    Franzen, L.E.2    Mathiesen, U.L.3
  • 51
    • 34548016755 scopus 로고    scopus 로고
    • Cardiovascular and metabolic risk factors: How can we improve outcomes in the high-risk patient?
    • Grundy SM: Cardiovascular and metabolHc risk factors: how can we improve outcomes in the high-risk patient? Am J Med 2007, 120(9 Suppl 1):S3-S8.
    • (2007) Am J Med , vol.120 , Issue.9 SUPPL. 1
    • Grundy, S.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.