Determination of the EC50 of levobupivacaine for femoral and sciatic perineural infusion after total knee arthroplasty

British Journal of Anaesthesia

Volumn 102, Issue 4, 2009, Pages 528-533

  McLeod, G A ^a   Dale, J ^a,d   Robinson, D ^a   Checketts, M ^a   Columb, M O ^b   Luck, J ^a,e   Wigderowitz, C ^a   Rowley, D ^a,c  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b MANCHESTER UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^c Royal College of Surgeons   (United Kingdom)

^d BRISTOL ROYAL INFIRMARY   (United Kingdom)

^e Golden Jubilee Hospital   (United Kingdom)

Author keywords

Anaesthetic techniques, regional, knee; Anaesthetics local; Pain, postoperative

Indexed keywords

CEFUROXIME; CYCLIZINE; DEXAMETHASONE; LEVOBUPIVACAINE; MORPHINE; ONDANSETRON; OXYCODONE; PARACETAMOL; PROPOFOL; TEMAZEPAM; BUPIVACAINE; DRUG DERIVATIVE; LOCAL ANESTHETIC AGENT;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; DRUG INFUSION; FEMORAL NERVE; HUMAN; HYPOTENSION; KNEE PAIN; NAUSEA; POSTOPERATIVE NAUSEA AND VOMITING; POSTOPERATIVE PAIN; PRIORITY JOURNAL; SCIATIC NERVE; TOTAL KNEE REPLACEMENT; VOMITING; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG ADMINISTRATION; DRUG EFFECT; JOINT CHARACTERISTICS AND FUNCTIONS; KNEE; KNEE ARTHROPLASTY; METHODOLOGY; MIDDLE AGED; NERVE BLOCK; PAIN ASSESSMENT; PATHOPHYSIOLOGY;

AGED; AGED, 80 AND OVER; ANESTHETICS, LOCAL; ARTHROPLASTY, REPLACEMENT, KNEE; BUPIVACAINE; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMORAL NERVE; HUMANS; KNEE JOINT; MIDDLE AGED; NERVE BLOCK; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; RANGE OF MOTION, ARTICULAR; SCIATIC NERVE;

EID: 62549131572     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aep010     Document Type: Article

References (14)

1. Capdevila X, Barthelet Y, Biboulet P, Ryckwaert Y, Rubenovitch J, d'Athis F. Effects of perioperative analgesic technique on the surgical outcome and duration of rehabilitation after major knee surgery. Anesthesiology 1999; 91: 8-15
2. Chelly JE, Greger J, Gebhard R, et al. Continuous femoral blocks improve recovery and outcome of patients undergoing total knee arthroplasty. J Arthroplasty 2001; 16: 436-45
3. Salinas FV, Liu SS, Mulroy MF. The effect of single-injection femoral nerve block versus continuous femoral nerve block after total knee arthroplasty on hospital length of stay and long-term functional recovery within an established clinical pathway. Anesth Analg 2006; 102: 1234-9
4. Davies AF, Segar EP, Murdoch J, Wright DE, Wilson IH. Epidural infusion or combined femoral and sciatic nerve blocks as perioperative analgesia for knee arthroplasty. Br J Anaesth 2004; 93: 368-74
5. Ben-David B, Schmalenberger K, Chelly JE. Analgesia after total knee arthroplasty: is continuous sciatic blockade needed in addition to continuous femoral blockade? Anesth Analg 2004; 98: 747-9
6. Zaric D, Boysen K, Christiansen C, Christiansen J, Stephensen S, Christensen B. A comparison of epidural analgesia with combined continuous femoral-sciatic nerve blocks after total knee replacement. Anesth Analg 2006; 102: 1240-6
7. Brodner G, Buerkle H, Van Aken H, et al. Postoperative analgesia after knee surgery: a comparison of three different concentrations of ropivacaine for continuous femoral nerve blockade. Anesth Analg 2007; 105: 256-62
8. Fowler SJ, Symons J, Sabato S, Myles PS. Epidural analgesia compared with peripheral nerve blockade after major knee surgery: a systematic review and meta-analysis of randomized trials. Br J Anaesth 2008; 100: 154-64
9. Lyons G, Columb M, Wilson RC, Johnson RV. Epidural pain relief in labour: potencies of levobupivacaine and racemic bupivacaine. Br J Anaesth 1998; 81: 899-901
10. McNamee DA, Parks L, Milligan KR. Post-operative analgesia following total knee replacement: an evaluation of the addition of an obturator nerve block to combined femoral and sciatic nerve block. Acta Anaesthesiol Scand 2002; 46: 95-9
11. Macalou D, Trueck S, Meuret P, et al. Postoperative analgesia after total knee replacement: the effect of an obturator nerve block added to the femoral 3-in-1 nerve block. Anesth Analg 2004; 99: 251-4
12. Singelyn FJ, Deyaert M, Joris D, Pendeville E, Gouverneur JM. Effects of intravenous patient-controlled analgesia with morphine, continuous epidural analgesia, and continuous three-in-one block on postoperative pain and knee rehabilitation after unilateral total knee arthroplasty. Anesth Analg 1998; 87: 88-92
13. Allen HW, Liu SS, Ware PD, Nairn CS, Owens BD. Peripheral nerve blocks improve analgesia after total knee replacement surgery. Anesth Analg 1998; 87: 93-7
14. Pham Dang C, Gautheron E, Guilley J, et al. The value of adding sciatic block to continuous femoral block for analgesia after total knee replacement. Reg Anesth Pain Med 2005; 30: 128-33