GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: The case of hERG K+ channel blockers

European Journal of Medicinal Chemistry

Volumn 44, Issue 5, 2009, Pages 1926-1932

  Ermondi, Giuseppe ^a   Visentin, Sonja ^a   Caron, Giulia ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

3D QSAR; ALMOND; GRIND; hERG; Molecular modelling

Indexed keywords

POTASSIUM CHANNEL HERG;

ARTICLE; CHEMOMETRIC ANALYSIS; COMPARATIVE MOLECULAR FIELD ANALYSIS; COMPARATIVE STUDY; METHODOLOGY; MOLECULAR MODEL; PREDICTION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; THREE DIMENSIONAL IMAGING;

ETHER-A-GO-GO POTASSIUM CHANNELS; HUMANS; HYDROPHOBICITY; MODELS, MOLECULAR; POTASSIUM CHANNEL BLOCKERS; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 62549129820     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2008.11.009     Document Type: Article

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