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Volumn 50, Issue 20, 2007, Pages 5039-5042

Influence of conformation on GRIND-based three-dimensional quantitative structure-activity relationship (3D-QSAR)

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; OXIDOSQUALENE CYCLASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 34948858433     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0704651     Document Type: Article
Times cited : (17)

References (9)
  • 1
    • 0034710718 scopus 로고    scopus 로고
    • GRid-INdependent descriptors (GRIND): A novel class of alignment-independent three-dimensional molecular descriptors
    • Pastor, M.; Cruciani, G.; McLay, I.; Pickett, S.; Clementi, S. GRid-INdependent descriptors (GRIND): a novel class of alignment-independent three-dimensional molecular descriptors. J. Med. Chem. 2004, 43, 3233-3243.
    • (2004) J. Med. Chem , vol.43 , pp. 3233-3243
    • Pastor, M.1    Cruciani, G.2    McLay, I.3    Pickett, S.4    Clementi, S.5
  • 3
    • 0038025347 scopus 로고    scopus 로고
    • Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase
    • Lenhart, A.; Reinert, D. J.; Aebi, J. D.; Dehmlow, H.; Morand, O. H.; Schulz, G. E. Binding structures and potencies of oxidosqualene cyclase inhibitors with the homologous squalene-hopene cyclase. J. Med. Chem. 2003, 46, 2083-2092.
    • (2003) J. Med. Chem , vol.46 , pp. 2083-2092
    • Lenhart, A.1    Reinert, D.J.2    Aebi, J.D.3    Dehmlow, H.4    Morand, O.H.5    Schulz, G.E.6
  • 4
    • 0038493664 scopus 로고    scopus 로고
    • Synthesis and structure-activity studies of novel orally active non-terpenoic 2,3-oxidosqualene cyclase inhibitors
    • Dehmlow, H.; Aebi, J. D.; Jolidon, S.; Ji, Y. H.; der Mark, E. M.; Himber, J.; Morand, O. H. Synthesis and structure-activity studies of novel orally active non-terpenoic 2,3-oxidosqualene cyclase inhibitors. J. Med. Chem. 2003, 46, 3354-3370.
    • (2003) J. Med. Chem , vol.46 , pp. 3354-3370
    • Dehmlow, H.1    Aebi, J.D.2    Jolidon, S.3    Ji, Y.H.4    der Mark, E.M.5    Himber, J.6    Morand, O.H.7
  • 5
    • 34948869163 scopus 로고    scopus 로고
    • CORINA;
    • CORINA; http://www.molecular-networks.com/online_demos/ corina_demo.html.
  • 6
    • 34948856240 scopus 로고    scopus 로고
    • OMEGA, version 2.1.0; OpenEye Science Software 3600 Cerrillos Road, Suite 1107, Santa Fe, NM, 2006
    • OMEGA, version 2.1.0; OpenEye Science Software (3600 Cerrillos Road, Suite 1107): Santa Fe, NM, 2006.
  • 8
    • 34948860937 scopus 로고    scopus 로고
    • MOE, version 2006.08; Chemical Computing Group Inc, Montreal, Quebec, Canada, 2006
    • MOE, version 2006.08; Chemical Computing Group Inc.: Montreal, Quebec, Canada, 2006.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.