Identification of Igf2, Igfbp2 and Enpp2 as estrogen-responsive genes in rat hippocampus

Endocrine Journal

Volumn 56, Issue 1, 2009, Pages 113-120

  Takeo, Chikari ^a   Ikeda, Kazuhiro ^a   Horje Inoue, Kuniko ^a   Inoue, Satoshi ^b  

^a SAITAMA MEDICAL UNIVERSITY   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Brain; Estrogen; Hippocampus; Microarray

Indexed keywords

AUTOTAXIN; CONNECTIVE TISSUE GROWTH FACTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; PROGESTERONE RECEPTOR; SOMATOMEDIN B;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL STRAIN GH3; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE CONTROL; GENE EXPRESSION REGULATION; HIPPOCAMPUS; HYPOTHALAMUS; NONHUMAN; OVARIECTOMY; POLYMERASE CHAIN REACTION; RAT;

ANIMALS; CELL LINE; ESTRADIOL; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HIPPOCAMPUS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 2; INSULIN-LIKE GROWTH FACTOR II; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN SPECIFICITY; PHOSPHORIC DIESTER HYDROLASES; PITUITARY GLAND; PYROPHOSPHATASES; RATS; RATS, WISTAR; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; SIGNAL TRANSDUCTION;

EID: 62549129109     PISSN: 09188959     EISSN: 13484540     Source Type: Journal    
DOI: 10.1507/endocrj.K08E-220     Document Type: Article

References (29)

1. Luine VN, Richards ST, Wu VY, Beck KD (1998) Estradiol enhances learning and memory in a spatial memory task and effects levels of monoaminergic neu-rotransmitters. Horm Behav 34: 149-162.
2. Schmidt R, Fazekas F, Reinhart B, Kapeller P, Fazekas G, Offenbacher H, Eber B, Schumacher M, Freidl W (1996) Estrogen replacement therapy in older women: a neuropsychological and brain MRI study. J Am Geriatr Soc 44: 1307-1313.
3. Simpkins JW, Green PS, Gridley KE, Singh M, de Fiebre NC, Rajakumar G (1997) Role of estrogen replacement therapy in memory enhancement and the prevention of neuronal loss associated with Alzheimer's disease. Am J Med 103: 19S-25S.
4. Mulnard RA, Cotman CW, Kawas C, van Dyck CH, Sano M, Doody R, Koss E, Pfeiffer E, Jin S, Gamst A, Grundman M, Thomas R, Thai LJ (2000) Estrogen replacement therapy for treatment of mild to moderate Alzheimer disease: a randomized controlled trial. Alzheimer's Disease Cooperative Study. JAMA 283: 1007-1015.
5. Henderson VW, Paganini-Hill A, Miller BL, Elble RJ, Reyes PF, Shoupe D, McCleary CA, Klein RA, Hake AM, Farlow MR (2000) Estrogen for Alzheimer's disease in women: randomized, double-blind, placebo- controlled trial. Neurology 54: 295-301.
6. Tulving E, Markowitsch HJ (1998) Episodic and declarative memory: role of the hippocampus. Hippocampus 8: 198-204.
7. McEwen BS, Alves SE (1999) Estrogen Actions in the Central Nervous System. Endocr Rev 20: 279-307.
8. Muramatsu M, Inoue S (2000) Estrogen receptors: how do they control reproductive and nonreproductive functions? Biochem Biophys Res Commun 270: 1-10.
9. McEwen B (2002) Estrogen actions throughout the brain. Recent Prog Horm Res 57: 357-384.
10. Watanabe T, Inoue S, Hiroi H, Orimo A, Muramatsu M (1999) NMDA receptor type 2D gene as target for estrogen receptor in the brain. Brain Res Mol Brain Res 63: 375-379.
11. Malyala A, Pattee P, Nagalla SR, Kelly MJ, Ronnekleiv OK (2004) Suppression subtractive hybridization and microarray identification of estrogen-regulated hypothalamic genes. Neurochem Res 29: 1189- 1200.
12. wasaki Y, Morishita M, Asai M, Onishi A, Yoshida M, Oiso Y, Inoue K (2004) Effects of hormones targeting nuclear receptors on transcriptional regulation of the growth hormone gene in the MtT/S rat somatotrope cell line. Neuroendocrinology 79: 229-236.
13. Kilvik K, Furu K, Haug E, Gautvik KM (1985) The mechanism of 17β-estradiol uptake into prolactin- producing rat pituitary cells (GH3 cells) in culture. Endocrinology 117: 967-975.
14. Ichikawa T, Horie-Inoue K, Ikeda K, Blumberg B, Inoue S (2006) Steroid and xenobiotic receptor SXR mediates vitamin K2-activated transcription of extracellular matrix-related genes and collagen accumulation in osteoblastic cells. J Biol Chem 281: 16927- 16934.
15. Deurveilher S, Cumyn EM, Peers T, Rusak B, Semba K (2008) Estradiol replacement enhances sleep deprivation-induced c-Fos immunoreactivity in forebrain arousal regions of ovariectomized rats. Am J Physiol Regul Integr Comp Physiol, epub (Aug 2008); doi:10.1152/ajpregu.90576.2008.
16. Wang Q, Li X, Wang L, Feng YH, Zeng R, Gorodeski G. (2004) Antiapoptotic effects of estrogen in normal and cancer human cervical epithelial cells. Endocrinology 145: 5568-5579.
17. Wise PM, Dubai DB, Wilson ME, Rau SW, Bottner M (2001) Minireview: neuroprotective effects of estrogen-new insights into mechanisms of action. Endocrinology 142: 969-973.
18. Gonzales KL, Tetel MJ, Wagner CK (2008) Estrogen receptor (ER) β modulates ERα responses to estrogens in the developing rat ventromedial nucleus of the hypothalamus. Endocrinology 149: 4615-4621.
19. Simpson ER, Davis SR (2001) Minireview: aromatase and the regulation of estrogen biosynthesis-some new perspectives. Endocrinology 142: 4589-4594.
20. Rotwein P, Burgess SK, Milbrandt JD, Krause JE (1988) Differential expression of insulin-like growth factor genes in rat central nervous system. Proc Natl AcadSci USA 85: 265-269.
21. Leventhal PS, Russell JW, Feldman EL (1999) IGFs and the nervous system. In: Rosefeld RG and Roberts CT (ed) The IGF System. Humana Press. New Jersey: 425-155.
22. Couce ME, Weatherington AJ, McGinty JF (1992) Expression of insulin-like growth factor-II (IGF-II) and IGF-II/mannose-6-phosphate receptor in the rat hippocampus: an in situ hybridization and immunocy- tochemical study. Endocrinology 131: 1636-1642.
23. Chesik D, De Keyser J, Wilczak N (2007) Insulin-like growth factor binding protein-2 as a regulator of IGF actions in CNS: implications in multiple sclerosis. Cytokine Growth Factor Rev 18: 267-278.
24. Ocrant I, Fay CT, Parmelee JT (1990) Characterization of insulin-like growth factor binding proteins produced in the rat central nervous system. Endocrinology 127: 1260-1267.
25. Arai T, Busby WJ, Clemmons DR (1996) Binding of insulin-like growth factor (IGF-I) or II to IGF-binding protein-2 enables it to bind to heparin and extracellular matrix. Endocrinology 137: 4571-4575.
26. Steen E, Terry BM, Rivera EJ, Cannon JL, Neely TR, Tavares R, Xu XJ, Wands JR, de la Monte SM (2005) Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease-is this type 3 diabetes? J Alzheimers Dis 7: 63- 80.
27. Messier C, Teutenberg K (2005) The role of insulin, insulin growth factor, and insulin-degrading enzyme in brain aging and Alzheimer's disease. Neural Plast 12: 311-328.
28. Azcoitia I, Sierra A, Garcia-Segura LM (1999) Neuroprotective effects of estradiol in the adult rat hippocampus: interaction with insulin-like growth factor-I signalling. J Neurosci Res 58: 815-822.
29. Fox MA, Alexander JK, Afshari FS, Colello RJ, Fuss B (2004) Phosphodiesterase-I alpha/autotaxin controls cytoskeletal organization and FAK phosphorylation during myelination. Mol CellNeurosci 27: 140-150.