Effect of excessive salt intake: Role of plasma sodium

Current Hypertension Reports

Volumn 11, Issue 2, 2009, Pages 91-97

  Reuter, Stefan ^a   Büssemaker, Eckhart ^a   Hausberg, Martin ^a   Pavenstädt, Hermann ^a   Hillebrand, Uta ^a  

^a UNIVERSITY HOSPITAL MÜNSTER   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

DIURETIC AGENT; SODIUM;

ARTERIAL STIFFNESS; BLOOD PRESSURE; BLOOD PRESSURE MONITORING; CARDIOVASCULAR RISK; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; ESSENTIAL HYPERTENSION; HEART LEFT VENTRICLE MASS; HUMAN; HYPERTENSION; KIDNEY FUNCTION; LIFESTYLE MODIFICATION; PATHOGENESIS; REVIEW; SALT INTAKE; SODIUM BLOOD LEVEL; SODIUM EXCRETION; SODIUM RESTRICTION; SODIUM RETENTION;

CELL SIZE; DIET, SODIUM-RESTRICTED; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; HUMANS; HYPERTENSION; MUSCLE, SMOOTH, VASCULAR; NITRIC OXIDE; RENIN-ANGIOTENSIN SYSTEM; SODIUM; SODIUM CHLORIDE, DIETARY; VASCULAR RESISTANCE; WATER-ELECTROLYTE BALANCE;

EID: 62549111753     PISSN: 15226417     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11906-009-0018-5     Document Type: Review

References (64)

1. World Health OrganizRtion: World health report 2002: reducing risks, promoting healthy life. Available at http://www.who.int/whr/2002. Accessed January 2009.
2. Lewington S, Whitlock G, Clarke R, et al.: Blood cholesterol and vascular mortality by age, sex, and blood pressure: A meta-analysis of individual data from 61 prospective studies with 55,000 vascular deaths. Lancet 2007, 370:1829-1839.
3. Meneton P, Jeunemaitre X, de Wardener HE, MacGregor GA: Links between dietary salt intake, renal salt handling, blood pressure, and cardiovascular diseases. Physiol Rev 2005, 85:679-715.
4. He FJ, MaIkandu ND, Sagnella GA, et al.: Plasma sodium: ignored and underestimated. Hypertension 2005, 45:98-102.
5. Ritz E: The history of salt - aspects of interest to the nephrologist. Nephrol Dial Transplant 1996, 11:969-975.
6. Frassetto L, Morris RC Jr, Sellmeyer DE, et al.: Diet, evolution and aging - the pathophysiologic effects of the post-agricultural inversion of the potassium-to-sodium and base-to-chloride ratios in the human diet. Eur J Nutr 2001, 40:200-213.
7. Geerling JC, Loewy AD: Central regulation of sodium appetite. Exp Physiol 2008, 93:177-209.
8. Geleijnse JM, Hofman A, Witteman JC, et al.: Long-term effects of neonatal sodium restriction on blood pressure. Hypertension 1997, 29:913-917.
9. Appel LJ, Brands MW, Daniels SR, et al.: Dietary approaches to prevent and treat hypertension: A scientific statement from the American Heart Association. Hypertension 2006, 47:296-308.
10. Titze J, Lang R, Ilies C, et al.: Osmotically inactive skin Na+ storage in rats. Am J Physiol Renal Physiol 2003, 285:F1108-F1117.
11. Titze J, Krause H, Hecht H, et al.: Reduced osmotically inactive Na storage capacity and hypertension in the Dahl model. Am J Physiol Renal Physiol 2002, 283:F134-F141.
12. Hamlyn JM, Blaustein MP: Sodium chloride, extracellular fluid volume, and blood pressure regulation. Am J Physiol 1986, 251:F563-F575.
13. Kurtz TW, Al-Bander HA, Morris RC Jr: "Salt-sensitive" essential hypertension in men. Is the sodium ion alone important? N Engl J Med 1987, 317:1043-1048.
14. de Wardener HE, He FJ, MacGregor GA: Plasma sodium and hypertension. Kidney Int 2004, 66:2454-2466.
15. Lago RM, Pencina MJ, Wang TJ, et al.: Interindividual variation in serum sodium and longitudinal blood pressure tracking in the Framingham Heart Study. J Hypertens 2008, 26:2121-2125.
16. Oberleithner H, Riethmuller C, Schillers H, et al.: Plasma sodium stiffens vascular endothelium and reduces nitric oxide release. Proc Natl Acad Sci U S A 2007, 104:16281-16286.
17. Kupari M, Koskinen P, Virolainen J: Correlates of left ventricular mass in a population sample aged 36 to 37 years. Focus on lifestyle and salt intake. Circulation 1994, 89:1041-1050.
18. Safar ME, Thuilliez C, Richard V, Benetos A: Pressure- independent contribution of sodium to large artery structure and function in hypertension. Cardiovasc Res 2000, 46:269-276.
19. Sanders PW: Salt intake, endothelial cell signaling, and progression of kidney disease. Hypertension 2004, 43:142-146.
20. Tuomilehto J, Jousilahti P, Rastenyte D, et al.: Urinary sodium excretion and cardiovascular mortality in Finland: A prospective study. Lancet 2001, 357:848-851.
21. Blackburn H, PrinAas R: Diet and hypertension: anthropology, epidemiology, and public health implications. Prog Biochem Pharmacol 1983, 19:31-79.
22. Stamler J, Rose G, Elliott P, et al.: Findings of the International Cooperative INTERSALT study. Hypertension 1991, 17:I9-I15.
23. Rikimaru T, Fujita Y, Okuda T, et al.: Responses of sodium balance, blood pressure, and other variables to sodium loading in Papua New Guinea highlanders. Am J Clin Nutr 1988, 47:502-508.
24. Poulter N, Khaw KT, Hopwood BE, et al.: Blood pressure and associated factors in a rural Kenyan community. Hypertension 1984, 6:810-813.
25. Forte JG, Miguel JMA Miguel MJ, et al.: Salt and blood pressure: a community trial. J Hum Hypertens 1989, 3:179-184.
26. Kemper W: Treatment of hypertensive vascular disease with rice diet. Am J Med 1948, 4:545-577.
27. Morgan T, Carney S, Myers J: Sodium and hypertension. A review of the role of sodium in pathogenesis and the action of diuretic drugs. Pharmacol Ther 1980, 9:395-418.
28. He FJ, Markandu ND, MacGregor GA: Importance of the renin system for determining blood pressure fall with acute salt restriction in hypertensive and normotensive whites. Hypertension 2001, 38:321-325.
29. Winer BM: The antihypertensive mechanisms of salt depletion induced by hydrochlorothiazide. Circulation 1961, 24:788-796.
30. Guyton AC: Kidneys and fluids in pressure regulation. Small volume but large pressure changes. Hypertension 1992, 19:I2-I8.
31. Charra B, Bergstrom J, Scribner BH: Blood pressure control in dialysis patients: Importance of the lag phenomenon. Am J Kidney Dis 1998, 32:720-724.
32. Montanari A, Vallisa D, Ragni G, et al.: Abnormal renal responses to calcium entry blockade in normotensive offspring of hypertensive parents. Hypertension 1988, 12:498-505.
33. Weder AB: Red-cell lithium-sodium countertransport and renal lithium clearance in hypertension. N Engl J Med 1986, 314:198-201.
34. Rettig R: Does the kidney play a role in the aetiology of primary hypertension? Evidence from renal transplantation studies in rats and humans. J Hum Hypertens 1993, 7:177-180.
35. Guidi E, Bianchi G, Rivolta E, et al.: Hypertension in man with a kidney transplant: Role of familial versus other factors. Nephron 1985, 41:14-21.
36. Stockand JD, Bao HF, Schenck J, et al.: Differential effects of protein kinase C on the levels of epithelial Na+ channel subunit proteins. J Biol Chem 2000, 275:25760-25765.
37. Oberleithner H: Is the vascular endothelium under the control of aldosterone? Facts and hypothesis. Pflugers Arch 2007, 454:187-193.
38. Aerrey F, Loffing J, Zecevic M, et al.: SGK1: aldosteroneinduced relay of Na+ transport regulation in distal kidney nephron cells. Cell Physiol Biochem 2003, 13:21-28.
39. Sindic A, Schlatter E: Cellular effects of guanylin and uroguanylin. J Am Soc Nephrol 2006, 17:607-616.
40. Verhave JC, Hillege HL, Burgerhof JG, et al.: Sodium intake affects urinary albumin excretion especially in overweight subjects. J Intern Med 2004, 256:324-330.
41. Guyton AC: Dominant role of the kidneys and accessory role of whole-body autoregulation in the pathogenesis of hypertension. Am J Hypertens 1989, 2:575-585.
42. Safar ME, London GM: Venous system in essential hypertension. Clin Sci (Lond) 1985, 69:497-504.
43. Zoccali C: Endothelial dysfunctionEand the kidney: emerging risk factors for renal insufficiency and cardiovascular outcomes in essential hypertension. J Am Soc Nephrol 2006, 17:S61-S63.
44. Tracy RE, Berenson GS, Cueto-Garcia L, et al.: Nephrosclerosis and aortic atherosclerosis from age 6 to 70 years in the United States and Mexico. Virchows Arch A Pathol Anat Histopathol 1992, 420:479-488.
45. Bonetti PO, Lerman AO, Lerman A: Endothelial dysfunction: a marker of atherosclerotic risk. Arterioscler Thromb Vasc Biol 2003, 23:168-175.
46. Franco M, Martinez F, Rodriguez-Iturbe B, et al.: Angiotensin II, interstitial inflammation, and the pathogenesis of salt-sensitive hypertension. Am J Physiol Renal Physiol 2006, 291:F1281-F1287.
47. Oberleithner H, Ludwig T, Riethmuller C, et al.: Human endothelium: target for aldosterone. Hypertension 2004, 43:952-956.
48. Oberleithner H, Riethmuller C, Ludwig T, et al.: Aldosterone remodels human endothelium. Acta Physiol (Oxf) 2006, 187:305-312.
49. Oberleithner H, Schneider SW, Albermann L, et al.: Endothelial cell swelling by aldosterone. J Membr Biol 2003, 196:163-172.
50. Gorelik J, Zhang Y, Sanchez D, et al.: Aldosterone acts via an ATP autocrine/paracrine system: The Edelman ATP hypothesis revisited. Proc Natl Acad Sci U S A 2005, 102:15000-15005.
51. Golestaneh N, Klein C, Valamanesh F, et al.: Mineralocorticoid receptor-mediated signaling regulates the ion gated sodium channel in vascular endothelial cells and requires an intact cytoskeleton. Biochem Biophys Res Commun 2001, 280:1300-1306.
52. Schiffrin EL: Effects of aldosterone on the vasculature. Hypertension 2006, 47:312-318.
53. Chen W, Valamanesh F, Mirshahi T, et al.: Aldosterone signaling modifies capillary formation by human bone marrow endothelial cells. Vascul Pharmacol 2004, 40:269-277.
54. Oberleithner H, Riethmuller C, Ludwig T, et al.: Differential action of steroid hormones on human endothelium. J Cell Sci 2006, 119:1926-1932.
55. Nagata D, Takahashi M, Sawai K, et al.: Molecular mechanism of the inhibitory effect of aldosterone on endothelial NO synthase activity. Hypertension 2006, 48:165-171.
56. Duffy SJ, Biegelsen ES, Eberhardt RT, et al.: Low-renin hypertension with relative aldosterone excess is associated with impaired NO-mediated vasodilation. Hypertension 2005, 46:707-713.
57. Anantharam A, Tian Y, Palmer LG: Open probability of the epithelial sodium channel is regulated by intracellular sodium. J Physiol 2006, 574:333-347.
58. Zieman SJ, Melenovsky V, Kass DA: Mechanisms, pathophysiology, and therapy of arterial stiffness. Arterioscler Thromb Vasc Biol 2005, 25:932-943.
59. Limas C, Westrum B, Limas CJ, Cohn JN: Effect of salt on the vascular lesions of spontaneously hypertensive rats. Hypertension 1980, 2:477-489.
60. Fleming I, Busse R: Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. Am J Physiol Regul Integr Comp Physiol 2003, 284:R1-R12.
61. Villar IC, Francis S, Webb A, et al.: Novel aspects of endothelium-dependent regulation of vascular tone. Kidney Int 2006, 70:840-853.
62. Rocha R, Funder JW: The pathophysiology of aldosterone in the cardiovascular system. Ann N Y Acad Sci 2002, 970:89-100.
63. Brilla CG, Weber KT: Mineralocorticoid excess, dietary sodium, and myocardial fibrosis. J Lab Clin Med 1992, 120:893-901.
64. Bagrov AY, Lakatta EG: The dietary sodium-blood pressure plot "stiffens." Hypertension 2004, 44:22-24.